Hereditary spastic paraplegia: clinical features and pathogenetic mechanisms

The Lancet Neurology

Volumn 7, Issue 12, 2008, Pages 1127-1138

  Salinas, Sara ^a   Proukakis, Christos ^b   Crosby, Andrew ^c   Warner, Thomas T ^b  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; AMINO ACID; CELL ADHESION MOLECULE; CELL ENZYME; CERULOPLASMIN; COPPER; CYANOCOBALAMIN; CYTOCHROME P450; CYTOCHROME P450 7B1; HEAT SHOCK PROTEIN 60; KINESIN; LIPOPROTEIN; SPASTIN; UNCLASSIFIED DRUG; VERY LONG CHAIN FATTY ACID; ZINC FINGER PROTEIN;

AMINO ACID BLOOD LEVEL; AUTOSOMAL DOMINANT INHERITANCE; AUTOSOMAL RECESSIVE INHERITANCE; CELL DEGENERATION; CERULOPLASMIN BLOOD LEVEL; CLINICAL EVALUATION; CLINICAL FEATURE; COPPER BLOOD LEVEL; DEGENERATIVE DISEASE; DIAGNOSTIC TEST; DISEASE COURSE; DISEASE MARKER; FAMILY HISTORY; FRAMESHIFT MUTATION; GENE; GENE LOCATION; GENE MAPPING; GENETIC ANALYSIS; HEREDITARY MOTOR SENSORY NEUROPATHY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN T CELL LEUKEMIA VIRUS; LIMB WEAKNESS; LIPOPROTEIN BLOOD LEVEL; NERVE CELL; NERVE FIBER TRANSPORT; NEUROLOGIC EXAMINATION; NUCLEAR MAGNETIC RESONANCE IMAGING; ONSET AGE; PATHOGENESIS; PATHOPHYSIOLOGY; PENETRANCE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRAMIDAL TRACT; REVIEW; SCHILLING TEST; SPASTIC PARAPLEGIA GENE; SPASTICITY; SPINAL CORD; SPINAL CORD MOTONEURON; X CHROMOSOME LINKAGE; ZINC FINGER MOTIF;

AXONS; CENTRAL NERVOUS SYSTEM; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INHERITANCE PATTERNS; MUTATION; NERVE DEGENERATION; NERVE TISSUE PROTEINS; NEURAL PATHWAYS; SPASTIC PARAPLEGIA, HEREDITARY;

EID: 55549094109     PISSN: 14744422     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1474-4422(08)70258-8     Document Type: Review

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