Structural and functional evolution of the L1 family: Are four adhesion molecules better than one?

Molecular and Cellular Neurosciences

Volumn 15, Issue 1, 2000, Pages 1-10

  Hortsch, Michael ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ADHESION MOLECULE;

AMINO ACID ANALYSIS; CELL ADHESION; EVOLUTION; GENE EXPRESSION; HUMAN; NONHUMAN; PHYLOGENY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STRUCTURE; REVIEW; STRUCTURE ANALYSIS;

EID: 0033952114     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1006/mcne.1999.0809     Document Type: Review

References (68)

1. Amores A., Force A., Yan Y. L., Joly L., Amemiya C., Fritz A., Ho R. K., Langeland J., Prince V., Wang Y. L., Westerfield M., Ekker M., Postlethwait J. H. Zebrafish hox clusters and vertebrate genome evolution. Science. 282:1998;1711-1714.
2. Bieber A. J., Snow P. M., Hortsch M., Patel N. H., Jacobs J. R., Traquina Z. R., Schilling J., Goodman C. S. Drosophila neuroglian: A member of the immunoglobulin superfamily with extensive homology to the vertebrate neural adhesion molecule L1. Cell. 59:1989;447-460.
3. Brümmendorf T., Hubert M., Treubert U., Leuschner R., Tarnok A., Rathjen F. G. The axonal recognition molecule F11 is a multifunctional protein: Specific domains mediate interactions with Ng-CAM and restrictin. Neuron. 10:1993;711-727.
4. Brümmendorf T., Kenwrick S., Rathjen F. G. Neural cell recognition molecule L1: From cell biology to human hereditary brain malformations. Curr. Opin. Neurobiol. 8:1998;87-97.
5. Burgoon M. P., Hazan R. B., Phillips G. R., Crossin K. L., Edelman G. M., Cunningham B. A. Functional analysis of posttranslational cleavage products of the neuron-glia cell adhesion molecule, Ng-CAM. J. Cell Biol. 130:1995;733-744.
6. Chen C.-L., Lampe D. J., Robertson H. M., Nardi J. B. Neuroglian is expressed on cells destined to form the prothorastic glands of Manduca embryos as they segregate from surrounding cells and rearrange during morphogenesis. Dev. Biol. 181:1997;1-13.
7. Cohen N. R., Taylor J. S. H., Scott L. B., Guillery R. W., Soriano P., Furley A. J. W. Errors in corticospinal axon guidance in mice lacking the neural cell adhesion molecule L1. Curr. Biol. 8:1997;26-33.
8. Collinson J. M., Marshall D., Gillespie C. S., Brophy P. J. Transient expression of neurofascin by oligodendrocytes at the onset of myelinogenesis: Implications for mechanisms of axon-glial interaction. Glia. 23:1998;11-23.
9. Dahlin-Huppe K., Berglund E. O., Ranscht B., Stallcup W. B. Mutational analysis of the L1 neuronal cell adhesion molecule identifies membrane-proximal amino acids of the cytoplasmic domain that are required for cytoskeletal anchorage. Mol. Cell. Neurosci. 9:1997;144-156.
10. Dahme M., Bartsch U., Martini R., Anliker B., Schachner M., Mantei N. Disruption of the mouse L1 gene leads to malformations of the nervous system. Nat. Genet. 17:1997;346-349.
11. -) and NrCAM at nodal axon segments. J. Cell Biol. 135:1996;1355-1367.
12. Davis J. Q., McLaughlin T., Bennett V. Ankyrin-binding proteins related to nervous system cell adhesion molecules: Candidates to provide transmembrane and intercellular connections in adult brain. J. Cell Biol. 121:1993;121-133.
13. de la Rosa E. J., Kayyem J. F., Roman J. M., Stierhof Y. D., Dreyer W. J., Schwarz U. Topologically restricted appearance in the developing chick retinotectal system of Bravo, a neural surface protein: Experimental modulation by environmental cues. J. Cell Biol. 111:1990;3087-3096.
14. Debiec H., Christensen E. I., Ronco P. M. The cell adhesion molecule L1 is developmentally regulated in the renal epithelium and is involved in kidney branching morphogenesis. J. Cell Biol. 143:1998;2067-2079.
15. Di Sciullo G., Donahue T., Schachner M., Bogen S. A. L1 antibodies block lymph node fibroblastic reticular matrix remodeling in vivo. J. Exp. Med. 187:1998;1953-1963.
16. Felsenfeld D. P., Hynes M. A., Skoler K. M., Furley A. J., Jessell T. M. TAG-1 can mediate homophilic binding, but neurite outgrowth on TAG-1 requires an L1-like molecule and beta 1 integrins. Neuron. 12:1994;675-690.
17. Felsenstein J. Evolutionary trees from DNA sequences: a maximum likelihood approach. J. Mol. Evol. 17:1981;368-376.
18. Fransen E., D'Hooge R., Van Camp G., Verhoye M., Sijbers J., Reyniers E., Soriano P., Kamiguchi H., Willemsen R., Koekkoek S. K., De Zeeuw C. I., De Deyn P. P., Van der Linden A., Lemmon V., Kooy R. F., Willems P. J. L1 knockout mice show dilated ventricles, vermis hypoplasia and impaired exploration patterns. Hum. Mol. Genet. 7:1998;999-1009.
19. Fransen E., Van Camp G., Vits L., Willems P. J. L1-associated diseases: Clinical geneticists divide, molecular geneticists unite. Hum. Mol. Genet. 6:1997;1625-1632.
20. Garver T. D., Ren Q., Tuvia S., Bennett V. Tyrosine phosphorylation at a site highly conserved in the L1 family of cell adhesion molecules abolishes ankyrin binding and increases lateral mobility of neurofascin. J. Cell Biol. 137:1997;703-714.
21. Grumet M. Structure, expression, and function of Ng-CAM, a member of the immunoglobulin superfamily involved in neuron-neuron and neuron-glia adhesion. J. Neurosci. Res. 31:1992;1-13.
22. Grumet M., Mauro V., Burgoon M. P., Edelman G. M., Cunningham B. A. Structure of a new nervous system glycoprotein, Nr-CAM, and relationship to subgroups of neural cell adhesion molecules. J. Cell Biol. 113:1991;1399-1412.
23. Hall S. G., Bieber A. J. Mutations in the Drosophila neuroglian cell adhesion molecule affect motor neuron pathfinding and peripheral nervous system patterning. J. Neurobiol. 32:1997;325-340.
24. Hassel B., Rathjen F. G., Volkmer H. Organization of the neurofascin gene and analysis of developmentally regulated alternative splicing. J. Biol. Chem. 272:1997;28742-28749.
25. Hillenbrand R., Molthagen M., Montag D., Schachner M. The close homologue of the neural adhesion molecule L1 (CHL1): Patterns of expression and promotion of neurite outgrowth by heterophilic interactions. Eur. J. Neurosci. 11:1999;813-826.
26. Holm J., Hillenbrand R., Steuber V., Bartsch U., Moos M., Lubbert H., Montag D., Schachner M. Structural features of a close homologue of L1 (CHL1) in the mouse: A new member of the L1 family of neural recognition molecules. Eur. J. Neurosci. 8:1996;1613-1629.
27. Hortsch M. The L1 family of neural cell adhesion molecules: Old proteins performing new tricks. Neuron. 17:1996;587-593.
28. Hortsch M., Bieber A. J., Patel N. H., Goodman C. S. Differential splicing generates a nervous system-specific form of Drosophila neuroglian. Neuron. 4:1990;697-709.
29. Hortsch M., Homer D., Malhotra J. D., Chang S., Frankel J., Jefford G., Dubreuil R. R. Structural requirements for "outside-in" and "inside-out" signaling by Drosophila neuroglian, a member of the L1 family of cell adhesion molecules. J. Cell Biol. 142:1998a;251-261.
30. Hortsch M., O'Shea K. S., Zhao G., Kim F., Vallejo Y., Dubreuil R. R. A conserved role for L1 as a transmembrane link between neuronal adhesion and membrane cytoskeleton assembly. Cell Adhes. Commun. 5:1998b;61-73.
31. Huang Y., Jellies J., Johansen K. M., Johansen J. Differential glycosylation of tractin and LeechCAM, two novel Ig superfamily members, regulates neurite extension and fascicle formation. J. Cell Biol. 138:1997;143-157.
32. Hubbe M., Kowitz A., Schirrmacher V., Schachner M., Altevogt P. L1 adhesion molecule on mouse leukocytes: Regulation and involvement in endothelial cell binding. Eur. J. Immunol. 23:1993;2927-2931.
33. Jouet M., Rosenthal A., Kenwrick S. Exon 2 of the gene for neural cell adhesion molecule L1 is alternatively spliced in B cells. Mol. Brain Res. 30:1995;378-380.
34. Kadmon G., Altevogt P. The cell adhesion molecule L1: Species- and cell-type-dependent multiple binding mechanisms. Differentiation. 61:1997;143-150.
35. Kamiguchi H., Lemmon V. A neuronal form of the cell adhesion molecule L1 contains a tyrosine-based signal required for sorting to the axonal growth cone. J. Neurosci. 18:1998;3749-3756.
36. Kamiguchi H., Long K. E., Pendergast M., Schaefer A. W., Rapoport I., Kirchhausen T., Lemmon V. The neural cell adhesion molecule L1 interacts with the AP-2 adaptor and is endocytosed via the clathrin-mediated pathway. J. Neurosci. 18:1998;5311-5321.
37. Kayyem J. F., Roman J. M., de la Rosa E. J., Schwarz U., Dreyer W. J. Bravo/Nr-CAM is closely related to the cell adhesion molecules L1 and Ng-CAM and has a similar heterodimer structure. J. Cell Biol. 118:1992;1259-1270.
38. Krushel L. A., Prieto A. L., Cunningham B. A., Edelman G. M. Expression patterns of the cell adhesion molecule Nr-CAM during histogenesis of the chick nervous system. Neuroscience. 53:1993;797-812.
39. Kujat R., Miragall F., Krause D., Dermietzel R., Wrobel K. H. Immunolocalization of the neural cell adhesion molecule L1 in non-proliferating epithelial cells of the male urogenital tract. Histochemistry. 103:1995;311-321.
40. Kunz S., Spirig M., Ginsburg C., Buchstaller A., Berger P., Lanz R., Rader C., Vogt L., Kunz B., Sonderegger P. Neurite fasciculation mediated by complexes of axonin-1 and Ng cell adhesion molecule. J. Cell Biol. 143:1998;1673-1690.
41. Lemmon V., McLoon S. C. The appearance of an L1-like molecule in the chick primary visual pathway. J. Neurosci. 6:1986;2987-2994.
42. Malhotra J. D., Tsiotra P., Karagogeos D., Hortsch M. Cis-activation of L1-mediated ankyrin recruitment by TAG-1 homophilic cell adhesion. J. Biol. Chem. 273:1998;33354-33359.
43. Montgomery A. M. P., Becker J. C., Siu C. H., Lemmon V. P., Cheresh D. A., Pancook J. D., Zhao X. N., Reisfeld R. A. Human neural cell-adhesion molecule L1 and rat homolog NILE are ligands for integrin alpha(V)beta(3). J. Cell Biol. 132:1996;475-485.
44. Morales G., Hubert M., Brümmendorf T., Treubert U., Tarnok A., Schwarz U., Rathjen F. G. Induction of axonal growth by heterophilic interactions between the cell surface recognition proteins F11 and Nr-CAM/Bravo. Neuron. 11:1993;1113-1122.
45. Moscoso L. M., Sanes J. R. Expression of four immunoglobulin superfamily adhesion molecules (L1, Nr-CAM/Bravo, neurofascin/ABGP, and N-CAM) in the developing mouse spinal cord. J. Comp. Neurol. 352:1995;321-334.
46. Pancook J. D., Reisfeld R. A., Varki N., Vitiello A., Fox R. I., Montgomery A. M. Expression and regulation of the neural cell adhesion molecule L1 on human cells of myelomonocytic and lymphoid origin. J. Immunol. 158:1997;4413-4421.
47. Pebusque M. J., Coulier F., Birnbaum D., Pontarotti P. Ancient large-scale genome duplications: Phylogenetic and linkage analyses shed light on chordate genome evolution. Mol. Biol. Evol. 15:1998;1145-1159.
48. Rathjen F. G., Wolff J. M., Chang S., Bonhoeffer F., Raper J. A. Neurofascin: A novel chick cell-surface glycoprotein involved in neurite-neurite interactions. Cell. 51:1987;841-849.
49. Reid R. A., Hemperly J. J. Variants of human L1 cell adhesion molecule arise through alternate splicing of RNA. J. Mol. Neurosci. 3:1992;127-135.
50. Ruppert M., Aigner S., Hubbe M., Yagita H., Altevogt P. The L1 adhesion molecule is a cellular ligand for VLA-5. J. Cell Biol. 1995;1881-1891.
51. Sakurai, T, Lustig, M, and, Grumet, M. 1999, Generation and initial characterization of Nr-CAM null mice. 29th Annual Meeting of the Society for Neuroscience. p, 8, 9.3.
52. B in premyelinated axons. J. Cell Biol. 143:1998;1305-1315.
53. Suter D. M., Pollerberg G. E., Buchstaller A., Giger R. J., Dreyer W. J., Sonderegger P. Binding between the neural cell adhesion molecules axonin-1 and Nr-CAM/Bravo is involved in neuron-glia interaction. J. Cell Biol. 131:1995;1067-1081.
54. Thor G., Probstmeier R., Schachner M. Characterization of the cell adhesion molecules L1, N-CAM and J1 in the mouse intestine. EMBO J. 6:1987;2581-2586.
55. Tuvia S., Garver T. D., Bennett V. The phosphorylation state of the FIGQY tyrosine of neurofascin determines ankyrin-binding activity and patterns of cell segregation. Proc. Natl. Acad. Sci. USA. 94:1997;12957-12962.
56. Volkmer H., Hassel B., Wolff J. M., Frank R., Rathjen F. G. Structure of the axonal surface recognition molecule neurofascin and its relationship to a neural subgroup of the immunoglobulin superfamily. J. Cell Biol. 118:1992;149-161.
57. Volkmer H., Leuschner R., Zacharias U., Rathjen F. G. Neurofascin induces neurites by heterophilic interactions with axonal NrCAM while NrCAM requires F11 on the axonal surface to extend neurites. J. Cell Biol. 135:1996;1059-1069.
58. Volkmer H., Zacharias U., Nörenberg U., Rathjen F. G. Dissection of complex molecular interactions of neurofascin with axonin-1, F11, and tenascin-R, which promote attachment and neurite formation of tectal cells. J. Cell Biol. 142:1998;1083-1093.
59. Walsh F. S., Doherty P. Neural cell adhesion molecules of the immunoglobulin superfamily: Role in axon growth and guidance. Annu. Rev. Cell Dev. Biol. 13:1997;425-456.
60. Wang B., Williams H., Du J. S., Terrett J., Kenwrick S. Alternative splicing of human NrCAM in neural and nonneural tissues. Mol. Cell. Neurosci. 10:1998;287-295.
61. Wei M. H., Karavanova I., Ivanov S. V., Popescu N. C., Keck C. L., Pack S., Eisen J. A., Lerman M. I. In silico-initiated cloning and molecular characterization of a novel human member of the L1 gene family of neural cell adhesion molecules. Hum. Genet. 103:1998;355-364.
62. Weiland U. M., Ott H., Bastmeyer M., Schaden H., Giordano S., Stuermer C. A. Expression of an L1-related cell adhesion molecule on developing CNS fiber tracts in zebrafish and its functional contribution to axon fasciculation. Mol. Cell. Neurosci. 9:1997;77-89.
63. Wong E. V., Schaefer A. W., Landreth G., Lemmon V. Involvement of p90rsk in neurite outgrowth mediated by the cell adhesion molecule L1. J. Biol. Chem. 271:1996;18217-18223.
64. Yip P. M., Zhao X., Montgomery A. M., Siu C. H. The Arg-Gly-Asp motif in the cell adhesion molecule L1 promotes neurite outgrowth via interaction with the alphavbeta3 integrin. Mol. Biol. Cell. 9:1998;277-290.
65. Zhang X., Davis J. Q., Carpenter S., Bennett V. Structural requirements for association of neurofascin with ankyrin. J. Biol. Chem. 273:1998;30785-30794.
66. Zhao G., Hortsch M. The analysis of genomic structures in the L1 family of cell adhesion molecules provides no evidence for exon shuffling events after the separation of arthropod and chordate lineages. Gene. 215:1998;47-55.
67. Zhao X., Yip P. M., Siu C. H. Identification of a homophilic binding site in immunoglobulin-like domain 2 of the cell adhesion molecule L1. J. Neurochem. 71:1998;960-971.
68. Zhou D., Lambert S., Malen P. L., Carpenter S., Boland L. M., Bennett V. AnkyrinG is required for clustering of voltage-gated Na channels at axon initial segments and for normal action potential firing. J. Cell Biol. 143:1998;1295-1304.