메뉴 건너뛰기




Volumn 5, Issue 10, 2008, Pages 1121-1138

Ultrasound targeted microbubble destruction for drug and gene delivery

Author keywords

Drug delivery; Gene therapy; Microbubble; Sonoporation; Ultrasound

Indexed keywords

ALBUMIN; BETA GALACTOSIDE; BETACELLULIN; BLEOMYCIN; CAMPTOTHECIN; CHLORAMPHENICOL ACETYLTRANSFERASE; COPOLYMER; DOXORUBICIN; GREEN FLUORESCENT PROTEIN; LIPID; LIPOPLEX; LIPOSOME; LUCIFERASE; METHOTREXATE; PACLITAXEL; PERFLUTREN; PHOSPHOLIPID; PLASMID DNA; PROTEIN P53; RESVERATROL; SCATTER FACTOR; SMAD7 PROTEIN; SMALL INTERFERING RNA; SONOVUE; TISSUE INHIBITOR OF METALLOPROTEINASE 3; TRANSCRIPTION FACTOR E2F; TRANSCRIPTION FACTOR PDX 1; UNINDEXED DRUG; VASCULOTROPIN; VIRUS VECTOR;

EID: 55149089888     PISSN: 17425247     EISSN: None     Source Type: Journal    
DOI: 10.1517/17425247.5.10.1121     Document Type: Review
Times cited : (127)

References (129)
  • 1
    • 0020672802 scopus 로고
    • Myocardial contrast echocardiography: A reproducible technique of myocardial opacification for identifying regional perfusion deficits
    • Tei C, Sakamaki T, Shah PM, et al. Myocardial contrast echocardiography: a reproducible technique of myocardial opacification for identifying regional perfusion deficits. Circulation 1983;67:585-93
    • (1983) Circulation , vol.67 , pp. 585-593
    • Tei, C.1    Sakamaki, T.2    Shah, P.M.3
  • 2
    • 12344262277 scopus 로고    scopus 로고
    • Cavitation bubble-driven cell and particle behavior in an ultrasound standing wave
    • Kuznetsova LA, Khanna S, Amso NN, et al. Cavitation bubble-driven cell and particle behavior in an ultrasound standing wave. J Acoust Soc Am 2005;117:104-12:
    • (2005) J Acoust Soc Am , vol.117 , pp. 104-112
    • Kuznetsova, L.A.1    Khanna, S.2    Amso, N.N.3
  • 3
    • 49849098427 scopus 로고    scopus 로고
    • Nonspherical oscillations of ultrasound contrast agent microbubbles
    • Dollet B, van der Meer SM, Garbin V, et al. Nonspherical oscillations of ultrasound contrast agent microbubbles. Ultrasound Med Biol 2008;34:1465-73
    • (2008) Ultrasound Med Biol , vol.34 , pp. 1465-1473
    • Dollet, B.1    van der Meer, S.M.2    Garbin, V.3
  • 4
    • 55149099699 scopus 로고    scopus 로고
    • Mathematical models for contrast bubble dynamics
    • Church CC, Allen JS. Mathematical models for contrast bubble dynamics. J Acoust Soc Am 2008;123:3111
    • (2008) J Acoust Soc Am , vol.123 , pp. 3111
    • Church, C.C.1    Allen, J.S.2
  • 6
    • 34948853399 scopus 로고    scopus 로고
    • The application of microbubbles for targeted drug delivery
    • Bull JL. The application of microbubbles for targeted drug delivery. Expert Opin Drug Deliv 2007;4:475-93
    • (2007) Expert Opin Drug Deliv , vol.4 , pp. 475-493
    • Bull, J.L.1
  • 7
    • 33745924402 scopus 로고    scopus 로고
    • Microbubble contrast agents: Targeted ultrasound imaging and ultrasound-assisted drug-delivery applications
    • Klibanov AL. Microbubble contrast agents: targeted ultrasound imaging and ultrasound-assisted drug-delivery applications. Invest Radiol 2006;41:3544-62
    • (2006) Invest Radiol , vol.41 , pp. 3544-3562
    • Klibanov, A.L.1
  • 8
    • 33847301456 scopus 로고    scopus 로고
    • Ultrasonic bubbles in medicine: Influence of the shell
    • Postema M, Schmitz G. Ultrasonic bubbles in medicine: influence of the shell. Ultrason Sonochem 2007;14:438-44
    • (2007) Ultrason Sonochem , vol.14 , pp. 438-444
    • Postema, M.1    Schmitz, G.2
  • 9
    • 34250843816 scopus 로고    scopus 로고
    • A study of the formulation design of acoustically active lipospheres as carriers for drug delivery
    • Fang JY, Hung CF, Liao MH, et al. A study of the formulation design of acoustically active lipospheres as carriers for drug delivery. Eur J Pharm Biopharm 2007;67:67-75
    • (2007) Eur J Pharm Biopharm , vol.67 , pp. 67-75
    • Fang, J.Y.1    Hung, C.F.2    Liao, M.H.3
  • 11
    • 0345600899 scopus 로고    scopus 로고
    • Development of a novel method for synthesis of a polymeric ultrasound contrast agent
    • El-Sherif DM, Wheatley MA. Development of a novel method for synthesis of a polymeric ultrasound contrast agent. J Biomed Mater Res A 2003;66:347-55
    • (2003) J Biomed Mater Res A , vol.66 , pp. 347-355
    • El-Sherif, D.M.1    Wheatley, M.A.2
  • 12
    • 0035812483 scopus 로고    scopus 로고
    • Optimization of spray drying by factorial design for production of hollow microspheres for ultrasound imaging
    • Narayan P, Marchant D, Wheatley MA. Optimization of spray drying by factorial design for production of hollow microspheres for ultrasound imaging. J Biomed Mater Res 2001;56:333-41
    • (2001) J Biomed Mater Res , vol.56 , pp. 333-341
    • Narayan, P.1    Marchant, D.2    Wheatley, M.A.3
  • 13
    • 0024368996 scopus 로고
    • Left heart opacification with peripheral venous injection of a new saccharide echo contrast agent in dogs
    • Smith MD, Elion JL, McClure RR, et al. Left heart opacification with peripheral venous injection of a new saccharide echo contrast agent in dogs. J Am Coll Cardiol 1989;13:1622-8
    • (1989) J Am Coll Cardiol , vol.13 , pp. 1622-1628
    • Smith, M.D.1    Elion, J.L.2    McClure, R.R.3
  • 14
    • 0021325853 scopus 로고
    • Superior intensity and reproducibility of SHU-454, a new right heart contrast agent
    • Smith MD, Kwan OL, Reiser HJ, et al. Superior intensity and reproducibility of SHU-454, a new right heart contrast agent. J Am Coll Cardiol 1984;3:992-8
    • (1984) J Am Coll Cardiol , vol.3 , pp. 992-998
    • Smith, M.D.1    Kwan, O.L.2    Reiser, H.J.3
  • 15
    • 0024998361 scopus 로고
    • Safety and efficacy of a new transpulmonary ultrasound contrast agent: Initial multicenter clinical results
    • Feinstein SB, Cheirif J, Ten Cate FJ, et al. Safety and efficacy of a new transpulmonary ultrasound contrast agent: initial multicenter clinical results. J Am Coll Cardiol 1990;16:316-24
    • (1990) J Am Coll Cardiol , vol.16 , pp. 316-324
    • Feinstein, S.B.1    Cheirif, J.2    Ten Cate, F.J.3
  • 16
    • 0025604521 scopus 로고
    • Lipid-coated ultrastable microbubbles as a contrast agent in neurosonography
    • Simon RH, Ho SY, D'Arrigo J, et al. Lipid-coated ultrastable microbubbles as a contrast agent in neurosonography. Invest Radiol 1990;25:1300-4
    • (1990) Invest Radiol , vol.25 , pp. 1300-1304
    • Simon, R.H.1    Ho, S.Y.2    D'Arrigo, J.3
  • 17
    • 0030874033 scopus 로고    scopus 로고
    • Gray-scale liver enhancement in VX2 tumor-bearing rabbits using BR14, a new ultrasonographic contrast agent
    • Schneider M, Broillet A, Bussat P, et al. Gray-scale liver enhancement in VX2 tumor-bearing rabbits using BR14, a new ultrasonographic contrast agent. Invest Radiol 1997;32:410-7
    • (1997) Invest Radiol , vol.32 , pp. 410-417
    • Schneider, M.1    Broillet, A.2    Bussat, P.3
  • 18
    • 0029956720 scopus 로고    scopus 로고
    • Myocardial contrast echocardiography: Reliable, safe, and efficacious myocardial perfusion assessment after intravenous injections of a new echocardiographic contrast agent
    • Meza M, Greener Y, Hunt R, et al. Myocardial contrast echocardiography: reliable, safe, and efficacious myocardial perfusion assessment after intravenous injections of a new echocardiographic contrast agent. Am Heart J 1996;132:871-81
    • (1996) Am Heart J , vol.132 , pp. 871-881
    • Meza, M.1    Greener, Y.2    Hunt, R.3
  • 19
    • 0031453226 scopus 로고    scopus 로고
    • Phase I clinical trials of MRX-115. A new ultrasound contrast agent
    • Fritz TA, Unger EC, Sutherland G, et al. Phase I clinical trials of MRX-115. A new ultrasound contrast agent. Invest Radiol 1997;32:735-40
    • (1997) Invest Radiol , vol.32 , pp. 735-740
    • Fritz, T.A.1    Unger, E.C.2    Sutherland, G.3
  • 20
    • 0029057163 scopus 로고
    • Noninvasive identification of acute myocardial ischemia and reperfusion with contrast ultrasound using intravenous perfluoropropane-exposed sonicated dextrose albumin
    • Porter TR, Xie F, Kricsfeld A, et al. Noninvasive identification of acute myocardial ischemia and reperfusion with contrast ultrasound using intravenous perfluoropropane-exposed sonicated dextrose albumin. J Am Coll Cardiol 1995;26:33-40
    • (1995) J Am Coll Cardiol , vol.26 , pp. 33-40
    • Porter, T.R.1    Xie, F.2    Kricsfeld, A.3
  • 21
    • 0032879188 scopus 로고    scopus 로고
    • Effect of filling gases on the backscatter from contrast microbubbles: Theory and in vivo measurements
    • Forsberg F, Basude R, Liu JB, et al. Effect of filling gases on the backscatter from contrast microbubbles: theory and in vivo measurements. Ultrasound Med Biol 1999;25:1203-11
    • (1999) Ultrasound Med Biol , vol.25 , pp. 1203-1211
    • Forsberg, F.1    Basude, R.2    Liu, J.B.3
  • 22
    • 0032040264 scopus 로고    scopus 로고
    • Clinical experience with AF0150 (Imagent US), a new ultrasound contrast agent
    • discussion S72-4
    • Pelura TJ. Clinical experience with AF0150 (Imagent US), a new ultrasound contrast agent. Acad Radiol 1998;5(Suppl 1):S69-71; discussion S72-4
    • (1998) Acad Radiol , vol.5 , Issue.SUPPL. 1
    • Pelura, T.J.1
  • 23
    • 33746792022 scopus 로고    scopus 로고
    • Postema M, Bouakaz A, ten Cate FJ, et al. Nitric oxide delivery by ultrasonic cracking: some limitations. Ultrasonics 2006;44(Suppl 1):e 109-13
    • Postema M, Bouakaz A, ten Cate FJ, et al. Nitric oxide delivery by ultrasonic cracking: some limitations. Ultrasonics 2006;44(Suppl 1):e 109-13
  • 24
    • 24944504409 scopus 로고    scopus 로고
    • Targeting vascular endothelium with avidin microbubbles
    • Korpanty G, Grayburn PA, Shohet RV, et al. Targeting vascular endothelium with avidin microbubbles. Ultrasound Med Biol 2005;31:1279-83
    • (2005) Ultrasound Med Biol , vol.31 , pp. 1279-1283
    • Korpanty, G.1    Grayburn, P.A.2    Shohet, R.V.3
  • 25
    • 0036020090 scopus 로고    scopus 로고
    • DNA-loaded albumin microbubbles enhance ultrasound-mediated transfection in vitro
    • Frenkel PA, Chen S, Thai T, et al. DNA-loaded albumin microbubbles enhance ultrasound-mediated transfection in vitro. Ultrasound Med Biol 2002;28:817-22
    • (2002) Ultrasound Med Biol , vol.28 , pp. 817-822
    • Frenkel, P.A.1    Chen, S.2    Thai, T.3
  • 26
    • 33748535091 scopus 로고    scopus 로고
    • Ultrasound-responsive polymer-coated microbubbles that bind and protect DNA
    • Lentacker I, De Geest BG, Vandenbroucke RE, et al. Ultrasound-responsive polymer-coated microbubbles that bind and protect DNA. Langmuir 2006;22:7273-8
    • (2006) Langmuir , vol.22 , pp. 7273-7278
    • Lentacker, I.1    De Geest, B.G.2    Vandenbroucke, R.E.3
  • 27
    • 35348919991 scopus 로고    scopus 로고
    • Ultrasound microbubble contrast agents: FundamentaLs and application to gene and drug delivery
    • Ferrara K, Pollard R, Borden M. Ultrasound microbubble contrast agents: fundamentaLs and application to gene and drug delivery. Ann Rev Biomed Eng 2007;9:415-47
    • (2007) Ann Rev Biomed Eng , vol.9 , pp. 415-447
    • Ferrara, K.1    Pollard, R.2    Borden, M.3
  • 28
    • 13244259404 scopus 로고    scopus 로고
    • Use of ultrasound contrast agents for gene or drug delivery in cardiovascular medicine
    • Bekeredjian R, Grayburn PA, Shohet RV. Use of ultrasound contrast agents for gene or drug delivery in cardiovascular medicine. J Am Coll Cardiol 2005;45:329-35
    • (2005) J Am Coll Cardiol , vol.45 , pp. 329-335
    • Bekeredjian, R.1    Grayburn, P.A.2    Shohet, R.V.3
  • 29
    • 0033795347 scopus 로고    scopus 로고
    • In vitro and in vivo transfection of plasmid DNA in the Dunning prostate tumor R3327-AT1 is enhanced by focused ultrasound
    • Huber PE, Pfisterer P. In vitro and in vivo transfection of plasmid DNA in the Dunning prostate tumor R3327-AT1 is enhanced by focused ultrasound. Gene Ther 2000;7:1516-25
    • (2000) Gene Ther , vol.7 , pp. 1516-1525
    • Huber, P.E.1    Pfisterer, P.2
  • 30
    • 0036197916 scopus 로고    scopus 로고
    • Pharmaceutical evaluation of gas-filled microparticles as gene delivery system
    • Seemann S, Hauff P, Schultze-Mosgau M, et al. Pharmaceutical evaluation of gas-filled microparticles as gene delivery system. Pharm Res 2002;19:250-7
    • (2002) Pharm Res , vol.19 , pp. 250-257
    • Seemann, S.1    Hauff, P.2    Schultze-Mosgau, M.3
  • 31
    • 33344477285 scopus 로고    scopus 로고
    • Lum AF, Borden MA, Dayton PA, et al. Ultrasound radiation force enables targeted deposition of model drug carriers loaded on microbubbles. J Control Release 2006;111:128-34
    • Lum AF, Borden MA, Dayton PA, et al. Ultrasound radiation force enables targeted deposition of model drug carriers loaded on microbubbles. J Control Release 2006;111:128-34
  • 32
    • 55149097766 scopus 로고    scopus 로고
    • Nanometerscale surface properties of mixed phopholipid monolayers and bilayers
    • Dufrene YBW, Green J, Lee G. Nanometerscale surface properties of mixed phopholipid monolayers and bilayers. Langmuir 1997;1:370-7
    • (1997) Langmuir , vol.1 , pp. 370-377
    • Dufrene, Y.B.W.1    Green, J.2    Lee, G.3
  • 33
    • 34347357709 scopus 로고    scopus 로고
    • Ultrasound-mediated gene delivery: Influence of contrast agent on transfection
    • Mehier-Humbert S, Yan F, Frinking P, et al. Ultrasound-mediated gene delivery: influence of contrast agent on transfection. Bioconjug Chem 2007;18:652-62
    • (2007) Bioconjug Chem , vol.18 , pp. 652-662
    • Mehier-Humbert, S.1    Yan, F.2    Frinking, P.3
  • 34
    • 55149112249 scopus 로고    scopus 로고
    • Available from
    • Available from: http://www.ncbi.nlm.nih.gov/books/bookres.fcgi/micad/ home.html
  • 35
    • 0032470386 scopus 로고    scopus 로고
    • Acoustically active lipospheres containing paclitaxel: A new therapeutic ultrasound contrast agent
    • Unger EC, McCreery TP, Sweitzer RH, et al. Acoustically active lipospheres containing paclitaxel: a new therapeutic ultrasound contrast agent. Invest Radiol 1998;33:886-92
    • (1998) Invest Radiol , vol.33 , pp. 886-892
    • Unger, E.C.1    McCreery, T.P.2    Sweitzer, R.H.3
  • 36
    • 34548541779 scopus 로고    scopus 로고
    • DNA and polylysine adsorption and multilayer construction onto cationic lipid-coated microbubbles
    • Borden MA, Caskey CF, Little E, et al. DNA and polylysine adsorption and multilayer construction onto cationic lipid-coated microbubbles. Langmuir 2007;23:9401-8
    • (2007) Langmuir , vol.23 , pp. 9401-9408
    • Borden, M.A.1    Caskey, C.F.2    Little, E.3
  • 37
    • 33846155891 scopus 로고    scopus 로고
    • Targeting the heart with gene therapy-optimized gene delivery methods
    • Muller OJ, Katus HA, Bekeredjian R. Targeting the heart with gene therapy-optimized gene delivery methods. Cardiovasc Res 2007;73:453-62
    • (2007) Cardiovasc Res , vol.73 , pp. 453-462
    • Muller, O.J.1    Katus, H.A.2    Bekeredjian, R.3
  • 38
    • 34547693063 scopus 로고    scopus 로고
    • Molecular ultrasound imaging using microbubble contrast agents
    • Dayton PA, Rychak JJ. Molecular ultrasound imaging using microbubble contrast agents. Front Biosci 2007;12:5124-42
    • (2007) Front Biosci , vol.12 , pp. 5124-5142
    • Dayton, P.A.1    Rychak, J.J.2
  • 39
    • 0034652031 scopus 로고    scopus 로고
    • Microbubble persistence in the microcirculation during ischemia/reperfusion and inflammation is caused by integrin- and complement-mediated adherence to activated leukocytes
    • Lindner JR, Coggins MP, Kaul S, et al. Microbubble persistence in the microcirculation during ischemia/reperfusion and inflammation is caused by integrin- and complement-mediated adherence to activated leukocytes. Circulation 2000;101:668-75
    • (2000) Circulation , vol.101 , pp. 668-675
    • Lindner, J.R.1    Coggins, M.P.2    Kaul, S.3
  • 40
    • 0034255292 scopus 로고    scopus 로고
    • Noninvasive imaging of inflammation by ultrasound detection of phagocytosed microbubbles
    • Lindner JR, Dayton PA, Coggins MP, et al. Noninvasive imaging of inflammation by ultrasound detection of phagocytosed microbubbles. Circulation 2000;102:531-8
    • (2000) Circulation , vol.102 , pp. 531-538
    • Lindner, J.R.1    Dayton, P.A.2    Coggins, M.P.3
  • 41
    • 0034727704 scopus 로고    scopus 로고
    • Noninvasive ultrasound imaging of inflammation using microbubbles targeted to activated leukocytes
    • Lindner JR, Song J, Xu F, et al. Noninvasive ultrasound imaging of inflammation using microbubbles targeted to activated leukocytes. Circulation 2000;102:2745-50
    • (2000) Circulation , vol.102 , pp. 2745-2750
    • Lindner, J.R.1    Song, J.2    Xu, F.3
  • 42
    • 0037117659 scopus 로고    scopus 로고
    • Noninvasive imaging of myocardial reperfusion injury using leukocyte-targeted contrast echocardiography
    • Christiansen JP, Leong-Poi H, Klibanov AL, et al. Noninvasive imaging of myocardial reperfusion injury using leukocyte-targeted contrast echocardiography. Circulation 2002;105:1764-67
    • (2002) Circulation , vol.105 , pp. 1764-1767
    • Christiansen, J.P.1    Leong-Poi, H.2    Klibanov, A.L.3
  • 43
    • 0032836212 scopus 로고    scopus 로고
    • Targeting and ultrasound imaging of microbubble-based contrast agents
    • Klibanov AL, Hughes MS, Villanueva FS, et al. Targeting and ultrasound imaging of microbubble-based contrast agents. Magma 1999;8:177-84
    • (1999) Magma , vol.8 , pp. 177-184
    • Klibanov, A.L.1    Hughes, M.S.2    Villanueva, F.S.3
  • 44
    • 34547396737 scopus 로고    scopus 로고
    • Ultrasound radiation force modulates ligand availability on targeted contrast agents
    • Borden MA, Sarancos MR, Stieger SM, et al. Ultrasound radiation force modulates ligand availability on targeted contrast agents. Mol Imaging 2006;5:139-47
    • (2006) Mol Imaging , vol.5 , pp. 139-147
    • Borden, M.A.1    Sarancos, M.R.2    Stieger, S.M.3
  • 45
    • 0026079627 scopus 로고
    • Echocardiographic contrast imaging of the human right heart: A multicenter study of the efficacy, safety, and reproducibility of intravenous SHU-454
    • Rovai D, Lombardi M, Cini G, et al. Echocardiographic contrast imaging of the human right heart: a multicenter study of the efficacy, safety, and reproducibility of intravenous SHU-454. J Clin Ultrasound 1991;19:523-30
    • (1991) J Clin Ultrasound , vol.19 , pp. 523-530
    • Rovai, D.1    Lombardi, M.2    Cini, G.3
  • 46
    • 0032191834 scopus 로고    scopus 로고
    • Gas-body-based contrast agent enhances vascular bioeffects of 1.09 MHz ultrasound on mouse intestine
    • Miller DL, Gies RA. Gas-body-based contrast agent enhances vascular bioeffects of 1.09 MHz ultrasound on mouse intestine. Ultrasound Med Biol 1998;24:1201-8
    • (1998) Ultrasound Med Biol , vol.24 , pp. 1201-1208
    • Miller, D.L.1    Gies, R.A.2
  • 47
    • 0034094045 scopus 로고    scopus 로고
    • The influence of ultrasound frequency and gas-body composition on the contrast agent-mediated enhancement of vascular bioeffects in mouse intestine
    • Miller DL, Gies RA. The influence of ultrasound frequency and gas-body composition on the contrast agent-mediated enhancement of vascular bioeffects in mouse intestine. Ultrasound Med Biol 2000;26:307-13
    • (2000) Ultrasound Med Biol , vol.26 , pp. 307-313
    • Miller, D.L.1    Gies, R.A.2
  • 48
    • 0034730121 scopus 로고    scopus 로고
    • Diagnostic ultrasound activation of contrast agent gas bodies induces capillary rupture in mice
    • Miller DL, Quddus J. Diagnostic ultrasound activation of contrast agent gas bodies induces capillary rupture in mice. Proc Natl Acad Sci USA 2000;97:10179-84
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 10179-10184
    • Miller, D.L.1    Quddus, J.2
  • 49
    • 0030689815 scopus 로고    scopus 로고
    • The influence of contrast agents on hemorrhage produced by lithotripter fields
    • Dalecki D, Raeman CH, Child SZ, et al. The influence of contrast agents on hemorrhage produced by lithotripter fields. Ultrasound Med Biol 1997;23:1435-9
    • (1997) Ultrasound Med Biol , vol.23 , pp. 1435-1439
    • Dalecki, D.1    Raeman, C.H.2    Child, S.Z.3
  • 50
    • 0030903747 scopus 로고    scopus 로고
    • Hemolysis in vivo from exposure to pulsed ultrasound
    • Dalecki D, Raeman CH, Child SZ, et al. Hemolysis in vivo from exposure to pulsed ultrasound. Ultrasound Med Biol 1997;23:307-13
    • (1997) Ultrasound Med Biol , vol.23 , pp. 307-313
    • Dalecki, D.1    Raeman, C.H.2    Child, S.Z.3
  • 51
    • 33751312312 scopus 로고    scopus 로고
    • Ultrasound, microbubbles and the blood-brain barrier
    • Meairs S, Alonso A. Ultrasound, microbubbles and the blood-brain barrier. Prog Biophys Mol Biol 2007;93:354-62
    • (2007) Prog Biophys Mol Biol , vol.93 , pp. 354-362
    • Meairs, S.1    Alonso, A.2
  • 52
    • 0036657984 scopus 로고    scopus 로고
    • Endothelial cell injury in venule and capillary induced by contrast ultrasonography
    • Kobayashi N, Yasu T, Yamada S, et al. Endothelial cell injury in venule and capillary induced by contrast ultrasonography. Ultrasound Med Biol 2002;28:949-56
    • (2002) Ultrasound Med Biol , vol.28 , pp. 949-956
    • Kobayashi, N.1    Yasu, T.2    Yamada, S.3
  • 53
    • 0034612205 scopus 로고    scopus 로고
    • Echocardiographic destruction of albumin microbubbles directs gene delivery to the myocardium
    • Shohet RV, Chen S, Zhou YT, et al. Echocardiographic destruction of albumin microbubbles directs gene delivery to the myocardium. Circulation 2000;101:2554-6
    • (2000) Circulation , vol.101 , pp. 2554-2556
    • Shohet, R.V.1    Chen, S.2    Zhou, Y.T.3
  • 54
    • 0034502618 scopus 로고    scopus 로고
    • Microbubble-enhanced ultrasound for vascular gene delivery
    • Lawrie A, Brisken AF, Francis SE, et al. Microbubble-enhanced ultrasound for vascular gene delivery. Gene Ther 2000;7:2023-7
    • (2000) Gene Ther , vol.7 , pp. 2023-2027
    • Lawrie, A.1    Brisken, A.F.2    Francis, S.E.3
  • 55
    • 0036227368 scopus 로고    scopus 로고
    • Development of safe and efficient novel nonviral gene transfer using ultrasound: Enhancement of transfection efficiency of naked plasmid DNA in skeletal muscle
    • Taniyama Y, Tachibana K, Hiraoka K, et al. Development of safe and efficient novel nonviral gene transfer using ultrasound: enhancement of transfection efficiency of naked plasmid DNA in skeletal muscle. Gene Ther 2002;9:372-80
    • (2002) Gene Ther , vol.9 , pp. 372-380
    • Taniyama, Y.1    Tachibana, K.2    Hiraoka, K.3
  • 56
    • 4043055869 scopus 로고    scopus 로고
    • Treatment of acute myocardial infarction by hepatocyte growth factor gene transfer: The first demonstration of myocardial transfer of a 'functional' gene using ultrasonic microbubble destruction
    • Kondo I, Ohmori K, Oshita A, et al. Treatment of acute myocardial infarction by hepatocyte growth factor gene transfer: the first demonstration of myocardial transfer of a 'functional' gene using ultrasonic microbubble destruction. J Am Coll Cardiol 2004;44:644-53
    • (2004) J Am Coll Cardiol , vol.44 , pp. 644-653
    • Kondo, I.1    Ohmori, K.2    Oshita, A.3
  • 57
    • 41149146130 scopus 로고    scopus 로고
    • Experimental research on therapeutic angiogenesis induced by hepatocyte growth factor directed by ultrasound-targeted microbubble destruction in rats
    • Li X, Wang Z, Ran H, et al. Experimental research on therapeutic angiogenesis induced by hepatocyte growth factor directed by ultrasound-targeted microbubble destruction in rats. J Ultrasound Med 2008;27:453-60
    • (2008) J Ultrasound Med , vol.27 , pp. 453-460
    • Li, X.1    Wang, Z.2    Ran, H.3
  • 58
    • 28344432329 scopus 로고    scopus 로고
    • Targeting of VEGF-mediated angiogenesis to rat myocardium using ultrasonic destruction of microbubbles
    • Korpanty G, Chen S, Shohet RV, et al. Targeting of VEGF-mediated angiogenesis to rat myocardium using ultrasonic destruction of microbubbles. Gene Ther 2005;12:1305-12
    • (2005) Gene Ther , vol.12 , pp. 1305-1312
    • Korpanty, G.1    Chen, S.2    Shohet, R.V.3
  • 59
    • 8644262429 scopus 로고    scopus 로고
    • Ultrasound-mediated microbubble destruction enhances VEGF gene delivery to the infarcted myocardium in rats
    • Zhigang W, Zhiyu L, Haitao R, et al. Ultrasound-mediated microbubble destruction enhances VEGF gene delivery to the infarcted myocardium in rats. Clin Imaging 2004;28:395-8
    • (2004) Clin Imaging , vol.28 , pp. 395-398
    • Zhigang, W.1    Zhiyu, L.2    Haitao, R.3
  • 60
    • 34548314613 scopus 로고    scopus 로고
    • Therapeutic arteriogenesis by ultrasound-mediated VEGF 165 plasmid gene delivety to chronically ischemic skeletal muscle
    • Leong-Poi H, Kuliszewski MA, Lekas M, et al. Therapeutic arteriogenesis by ultrasound-mediated VEGF 165 plasmid gene delivety to chronically ischemic skeletal muscle. Circ Res 2007;101:295-303
    • (2007) Circ Res , vol.101 , pp. 295-303
    • Leong-Poi, H.1    Kuliszewski, M.A.2    Lekas, M.3
  • 61
    • 11144356848 scopus 로고    scopus 로고
    • Local delivery of E2F decoy oligodeoxynudeotides using ultrasound with microbubble agent (Optison) inhibits intimal hyperplasia after balloon injury in rat casotid artery model
    • Hashiya N, Aoki M, Tachibana K, et al. Local delivery of E2F decoy oligodeoxynudeotides using ultrasound with microbubble agent (Optison) inhibits intimal hyperplasia after balloon injury in rat casotid artery model. Biochem Biophys Res Commun 2004;317:508-14
    • (2004) Biochem Biophys Res Commun , vol.317 , pp. 508-514
    • Hashiya, N.1    Aoki, M.2    Tachibana, K.3
  • 62
    • 10744229758 scopus 로고    scopus 로고
    • Systemic targeted delivery of antisense with perflourobutane gas microbubble carrier reduced neointimal formation in the porcine coronary restenosis model
    • Kipshidze NN, Porter TR, Dangas G, et al. Systemic targeted delivery of antisense with perflourobutane gas microbubble carrier reduced neointimal formation in the porcine coronary restenosis model. Cardiovasc Radiat Med 2003;4:152-9
    • (2003) Cardiovasc Radiat Med , vol.4 , pp. 152-159
    • Kipshidze, N.N.1    Porter, T.R.2    Dangas, G.3
  • 63
    • 0037066034 scopus 로고    scopus 로고
    • Local delivery of plasmid DNA into rat carotid artery using ultrasound
    • Taniyama Y, Tachibana K, Hiraoka K, et al. Local delivery of plasmid DNA into rat carotid artery using ultrasound. Circulation 2002;105:1233-9
    • (2002) Circulation , vol.105 , pp. 1233-1239
    • Taniyama, Y.1    Tachibana, K.2    Hiraoka, K.3
  • 64
    • 33744540646 scopus 로고    scopus 로고
    • Myocardium-targeted delivery of endothelial progenitor cells by ultrasound-mediated microbubble destruction improves cardiac function via an angiogenic response
    • Zen K, Okigaki M, Hosokawa Y, et al. Myocardium-targeted delivery of endothelial progenitor cells by ultrasound-mediated microbubble destruction improves cardiac function via an angiogenic response. J Mol Cell Cardiol 2006;40:799-809
    • (2006) J Mol Cell Cardiol , vol.40 , pp. 799-809
    • Zen, K.1    Okigaki, M.2    Hosokawa, Y.3
  • 65
    • 28444462126 scopus 로고    scopus 로고
    • Hepatocyte growth factor delivered by ultrasound-mediated destruction of microbubbles induces proliferation of cardiomyocytes and amelioration of left ventricular contractile function in Doxorubicin-induced cardiomyopathy
    • Iwasaki M, Adachi Y, Nishiue T, et al. Hepatocyte growth factor delivered by ultrasound-mediated destruction of microbubbles induces proliferation of cardiomyocytes and amelioration of left ventricular contractile function in Doxorubicin-induced cardiomyopathy. Stem Cells 2005;23:1589-97
    • (2005) Stem Cells , vol.23 , pp. 1589-1597
    • Iwasaki, M.1    Adachi, Y.2    Nishiue, T.3
  • 66
    • 0034124257 scopus 로고    scopus 로고
    • Ten-fold augmentation of endothelial uptake of vascular endothelial growth factor with ultrasound after systemic administration
    • Mukherjee D, Wong J, Griffin B, et al. Ten-fold augmentation of endothelial uptake of vascular endothelial growth factor with ultrasound after systemic administration. J Am Coll Cardiol 2000;35:1678-86
    • (2000) J Am Coll Cardiol , vol.35 , pp. 1678-1686
    • Mukherjee, D.1    Wong, J.2    Griffin, B.3
  • 67
    • 13244274387 scopus 로고    scopus 로고
    • Augmentation of cardiac protein delivery using ultrasound targeted microbubble destruction
    • Bekeredjian R, Chen S, Grayburn PA, et al. Augmentation of cardiac protein delivery using ultrasound targeted microbubble destruction. Ultrasound Med Biol 2005;31:687-91
    • (2005) Ultrasound Med Biol , vol.31 , pp. 687-691
    • Bekeredjian, R.1    Chen, S.2    Grayburn, P.A.3
  • 68
    • 12344273726 scopus 로고    scopus 로고
    • The blood-brain barrier: Bottleneck in brain drug development
    • Pardridge WM. The blood-brain barrier: bottleneck in brain drug development. NeuroRx 2005;2:3-14
    • (2005) NeuroRx , vol.2 , pp. 3-14
    • Pardridge, W.M.1
  • 69
    • 0028866665 scopus 로고
    • Scanning and transmission electron microscopic studies of microvascular pathology in the osmotically impaired blood-brain barrier
    • Lossinsky AS, Vorbrodt AW, Wisniewski HM. Scanning and transmission electron microscopic studies of microvascular pathology in the osmotically impaired blood-brain barrier. J Neurocytol 1995;24:795-806
    • (1995) J Neurocytol , vol.24 , pp. 795-806
    • Lossinsky, A.S.1    Vorbrodt, A.W.2    Wisniewski, H.M.3
  • 70
    • 0033911807 scopus 로고    scopus 로고
    • Intracarotid infusion of hypertonic mannitol changes permeability of blood-brain barrier to methotrexate in rats
    • Pan GY, Liu XD, Liu GQ. Intracarotid infusion of hypertonic mannitol changes permeability of blood-brain barrier to methotrexate in rats. Acta Pharmacol Sin 2000;21:613-6
    • (2000) Acta Pharmacol Sin , vol.21 , pp. 613-616
    • Pan, G.Y.1    Liu, X.D.2    Liu, G.Q.3
  • 71
    • 0033962411 scopus 로고    scopus 로고
    • Inflammatory mediators and modulation of blood-brain barrier permeability
    • Abbott NJ. Inflammatory mediators and modulation of blood-brain barrier permeability. Cell Mol Neurobiol 2000;20:131-47
    • (2000) Cell Mol Neurobiol , vol.20 , pp. 131-147
    • Abbott, N.J.1
  • 72
    • 0027991897 scopus 로고
    • Intracarotid infusion of bradykinin selectively increases blood-tumor permeability in 9L and C6 brain tumors
    • Nomura T, Inamura T, Black KL. Intracarotid infusion of bradykinin selectively increases blood-tumor permeability in 9L and C6 brain tumors. Brain Res 1994;659:62-6
    • (1994) Brain Res , vol.659 , pp. 62-66
    • Nomura, T.1    Inamura, T.2    Black, K.L.3
  • 73
    • 0027973489 scopus 로고
    • Intracarotid infusion of RMP-7, a bradykinin analog: A method for selective drug delivery to brain tumors
    • Inamura T, Nomura T, Bartus RT, et al. Intracarotid infusion of RMP-7, a bradykinin analog: a method for selective drug delivery to brain tumors. J Neurosurg 1994;81:752-8
    • (1994) J Neurosurg , vol.81 , pp. 752-758
    • Inamura, T.1    Nomura, T.2    Bartus, R.T.3
  • 74
    • 41849085930 scopus 로고    scopus 로고
    • Clinical utility of contrast-enhanced ultrasound in neurosonology
    • Droste DW. Clinical utility of contrast-enhanced ultrasound in neurosonology. Eur Neurol 2008;59(Suppl 1):2-8
    • (2008) Eur Neurol , vol.59 , Issue.SUPPL. 1 , pp. 2-8
    • Droste, D.W.1
  • 75
    • 0029148503 scopus 로고
    • Histologic effects of high intensity pulsed ultrasound exposure with subharmonic emission in rabbit brain in vivo
    • Vykhodtseva NI, Hynynen K, Damianou C. Histologic effects of high intensity pulsed ultrasound exposure with subharmonic emission in rabbit brain in vivo. Ultrasound Med Biol 1995;21:969-79
    • (1995) Ultrasound Med Biol , vol.21 , pp. 969-979
    • Vykhodtseva, N.I.1    Hynynen, K.2    Damianou, C.3
  • 76
    • 0034876083 scopus 로고    scopus 로고
    • Noninvasive MR imaging-guided focal opening of the blood-brain barrier: In rabbits
    • Hynynen K, McDannold N, Vykhodtseva N, et al. Noninvasive MR imaging-guided focal opening of the blood-brain barrier: in rabbits. Radiology 2001;220:640-6
    • (2001) Radiology , vol.220 , pp. 640-646
    • Hynynen, K.1    McDannold, N.2    Vykhodtseva, N.3
  • 77
    • 33748483260 scopus 로고    scopus 로고
    • Focal disruption of the blood-brain barrier due to 260-kHz ultrasound bursts: A method for molecular imaging and targeted drug delivery
    • Hynynen K, McDannold N, Vykhodtseva N, et al. Focal disruption of the blood-brain barrier due to 260-kHz ultrasound bursts: a method for molecular imaging and targeted drug delivery. J Neurosurg 2006;105:445-54
    • (2006) J Neurosurg , vol.105 , pp. 445-454
    • Hynynen, K.1    McDannold, N.2    Vykhodtseva, N.3
  • 78
    • 43849110904 scopus 로고    scopus 로고
    • Effects of acoustic parameters and ultrasound contrast agent dose on focused-ultrasound induced blood-brain barrier disruption
    • McDannold N, Vykhodtseva N, Hynynen K. Effects of acoustic parameters and ultrasound contrast agent dose on focused-ultrasound induced blood-brain barrier disruption. Ultrasound Med Biol 2008;34:930-7
    • (2008) Ultrasound Med Biol , vol.34 , pp. 930-937
    • McDannold, N.1    Vykhodtseva, N.2    Hynynen, K.3
  • 79
    • 42949140276 scopus 로고    scopus 로고
    • Blood-brain barrier disruption induced by focused ultrasound and circulating preformed microbubbles appears to be characterized by the mechanical index
    • McDannold N, Vykhodtseva N, Hynynen K. Blood-brain barrier disruption induced by focused ultrasound and circulating preformed microbubbles appears to be characterized by the mechanical index. Ultrasound Med Biol 2008;34:834-40
    • (2008) Ultrasound Med Biol , vol.34 , pp. 834-840
    • McDannold, N.1    Vykhodtseva, N.2    Hynynen, K.3
  • 80
    • 10044278240 scopus 로고    scopus 로고
    • Local and reversible blood-brain barrier disruption by noninvasive focused ultrasound at frequencies suitable for trans-skull sonications
    • Hynynen K, McDannold N, Sheikov NA, et al. Local and reversible blood-brain barrier disruption by noninvasive focused ultrasound at frequencies suitable for trans-skull sonications. Neuroimage 2005;24:12-20
    • (2005) Neuroimage , vol.24 , pp. 12-20
    • Hynynen, K.1    McDannold, N.2    Sheikov, N.A.3
  • 81
    • 55149083186 scopus 로고    scopus 로고
    • Kinoshita M, McDannold N, Jolesz FA, et al. Targeted delivery of antibodies through the blood-brain barrier by MRI-guided focused ultrasound. Biochem Biophys Res Commun 2006;340:1085-90**82 Sheikov N, McDannold N, Vykhodtseva N, et al. Cellular mechanisms of the blood-brain barrier opening induced by ultrasound in presence of microbubbles. Ultrasound Med Biol 2004;30:979-89
    • Kinoshita M, McDannold N, Jolesz FA, et al. Targeted delivery of antibodies through the blood-brain barrier by MRI-guided focused ultrasound. Biochem Biophys Res Commun 2006;340:1085-90**82 Sheikov N, McDannold N, Vykhodtseva N, et al. Cellular mechanisms of the blood-brain barrier opening induced by ultrasound in presence of microbubbles. Ultrasound Med Biol 2004;30:979-89
  • 83
    • 34547121440 scopus 로고    scopus 로고
    • Targeted delivery of doxorubicin to the rat brain at therapeutic levels using MRL-guided focused ultrasound
    • Treat LH, McDannold N, Vykhodtseva N, et al. Targeted delivery of doxorubicin to the rat brain at therapeutic levels using MRL-guided focused ultrasound. Int J Cancer 2007;121:901-7
    • (2007) Int J Cancer , vol.121 , pp. 901-907
    • Treat, L.H.1    McDannold, N.2    Vykhodtseva, N.3
  • 84
    • 34548130700 scopus 로고    scopus 로고
    • Quantitative evaluation of focused ultrasound with a contrast agent on blood-brain barrier disruption
    • Yang FY, Fu WM, Yang RS, et al. Quantitative evaluation of focused ultrasound with a contrast agent on blood-brain barrier disruption. Ultrasound Med Biol 2007;33:1421-7
    • (2007) Ultrasound Med Biol , vol.33 , pp. 1421-1427
    • Yang, F.Y.1    Fu, W.M.2    Yang, R.S.3
  • 85
    • 35848934576 scopus 로고    scopus 로고
    • Spatio-temporal analysis of molecular delivery through the blood-brain barrier using focused ultrasound
    • Choi JJ, Pernot M, Brown TR, et al. Spatio-temporal analysis of molecular delivery through the blood-brain barrier using focused ultrasound. Phys Med Biol 2007;52:5509-30
    • (2007) Phys Med Biol , vol.52 , pp. 5509-5530
    • Choi, J.J.1    Pernot, M.2    Brown, T.R.3
  • 86
    • 33845675648 scopus 로고    scopus 로고
    • Noninvasive, transcranial and localized opening of the blood-brain barrier using focused ultrasound in mice
    • Choi JJ, Pernot M, Small SA, et al. Noninvasive, transcranial and localized opening of the blood-brain barrier using focused ultrasound in mice. Ultrasound Med Biol 2007;33:9-104
    • (2007) Ultrasound Med Biol , vol.33 , pp. 9-104
    • Choi, J.J.1    Pernot, M.2    Small, S.A.3
  • 87
    • 0037138499 scopus 로고    scopus 로고
    • Influence of injection site, microvascular pressure and ultrasound variables on microbubble-mediated delivery of microspheres to muscle
    • Song J, Chappell JC, Qi M, et al. Influence of injection site, microvascular pressure and ultrasound variables on microbubble-mediated delivery of microspheres to muscle. J Am Coll Cardiol 2002;39:726-31
    • (2002) J Am Coll Cardiol , vol.39 , pp. 726-731
    • Song, J.1    Chappell, J.C.2    Qi, M.3
  • 88
    • 0032578520 scopus 로고    scopus 로고
    • Delivery of colloidal particles and red blood cells to tissue through microvessel ruptures created by targeted microbubble destruction with ultrasound
    • Price RJ, Skyba DM, Kaul S, et al. Delivery of colloidal particles and red blood cells to tissue through microvessel ruptures created by targeted microbubble destruction with ultrasound. Circulation 1998;98:1264-7
    • (1998) Circulation , vol.98 , pp. 1264-1267
    • Price, R.J.1    Skyba, D.M.2    Kaul, S.3
  • 89
    • 33947213565 scopus 로고    scopus 로고
    • Local delivery system of cytotoxic agents to tumors by focused sonoporation
    • Iwanaga K, Tominaga K, Yamamoto K, et al. Local delivery system of cytotoxic agents to tumors by focused sonoporation. Cancer Gene Ther 2007;14:354-63
    • (2007) Cancer Gene Ther , vol.14 , pp. 354-363
    • Iwanaga, K.1    Tominaga, K.2    Yamamoto, K.3
  • 91
    • 0030915257 scopus 로고    scopus 로고
    • Evaluation of lipid-coated microbubbles as a delivery vehicle for Taxol in brain tumor therapy
    • discussion 1266-8
    • Ho SY, Barbarese E, D'Arrigo JS, et al. Evaluation of lipid-coated microbubbles as a delivery vehicle for Taxol in brain tumor therapy. Neurosurgery 1997;40:1260-6; discussion 1266-8
    • (1997) Neurosurgery , vol.40 , pp. 1260-1266
    • Ho, S.Y.1    Barbarese, E.2    D'Arrigo, J.S.3
  • 92
    • 33750813534 scopus 로고    scopus 로고
    • Therapeutic effects of paclitaxel-containing ultrasound contrast agents
    • Tartis MS, McCallan J, Lum AF, et al. Therapeutic effects of paclitaxel-containing ultrasound contrast agents. Ultrasound Med Biol 2006;32:1771-80
    • (2006) Ultrasound Med Biol , vol.32 , pp. 1771-1780
    • Tartis, M.S.1    McCallan, J.2    Lum, A.F.3
  • 93
    • 33947302582 scopus 로고    scopus 로고
    • Kheirolomoom A, Dayton PA, Lum AF, et al. Acoustically active microbubbles conjugated to liposomes: characterization of a proposed drug delivery vehicle. J Control Release 2007;118:275-84
    • Kheirolomoom A, Dayton PA, Lum AF, et al. Acoustically active microbubbles conjugated to liposomes: characterization of a proposed drug delivery vehicle. J Control Release 2007;118:275-84
  • 94
    • 0343247711 scopus 로고    scopus 로고
    • Biodegradation and biocompatibility of PLA and PLGA microspheres
    • Shive MS, Anderson JM. Biodegradation and biocompatibility of PLA and PLGA microspheres. Adv Drug Deliv Rev 1997;28:5-24
    • (1997) Adv Drug Deliv Rev , vol.28 , pp. 5-24
    • Shive, M.S.1    Anderson, J.M.2
  • 95
    • 34547813763 scopus 로고    scopus 로고
    • Multifunctional nanoparticles for combining ultrasonic tumor imaging and targeted chemotherapy
    • Rapoport N, Gao Z, Kennedy A. Multifunctional nanoparticles for combining ultrasonic tumor imaging and targeted chemotherapy. J Natl Cancer Inst 2007;99:1095-106
    • (2007) J Natl Cancer Inst , vol.99 , pp. 1095-1106
    • Rapoport, N.1    Gao, Z.2    Kennedy, A.3
  • 96
    • 48149101117 scopus 로고    scopus 로고
    • Drug-loaded nano/microbubbles for combining ultrasonography and targeted chemotherapy
    • Gao Z, Kennedy AM, Christensen DA, et al. Drug-loaded nano/microbubbles for combining ultrasonography and targeted chemotherapy. Ultrasonics 2007;48:260-70
    • (2007) Ultrasonics , vol.48 , pp. 260-270
    • Gao, Z.1    Kennedy, A.M.2    Christensen, D.A.3
  • 97
    • 9644292798 scopus 로고    scopus 로고
    • Ultrasound-enhanced tumor targeting of polymeric micellar drug carriers
    • Gao Z, Fain HD, Rapoport N. Ultrasound-enhanced tumor targeting of polymeric micellar drug carriers. Mol Pharm 2004;1:317-30
    • (2004) Mol Pharm , vol.1 , pp. 317-330
    • Gao, Z.1    Fain, H.D.2    Rapoport, N.3
  • 98
    • 45049086717 scopus 로고    scopus 로고
    • Enhancing ultrasound-mediated cell membrane permeabilisation (sonoporation) using a high frequency pulse regime and implications for ultrasound-aided cancer chemotherapy
    • Li YS, Reid CN, McHale AP. Enhancing ultrasound-mediated cell membrane permeabilisation (sonoporation) using a high frequency pulse regime and implications for ultrasound-aided cancer chemotherapy. Cancer Lett 2008;266:156452
    • (2008) Cancer Lett , vol.266 , pp. 156452
    • Li, Y.S.1    Reid, C.N.2    McHale, A.P.3
  • 99
    • 34548841402 scopus 로고    scopus 로고
    • Ultrasound Targeted Microbubble Destruction Increases Capillary Permeability in Hepatomas
    • Bekeredjian R, Kroll RD, Fein E, et al. Ultrasound Targeted Microbubble Destruction Increases Capillary Permeability in Hepatomas. Ultrasound Med Biol 2007;33:1592-8
    • (2007) Ultrasound Med Biol , vol.33 , pp. 1592-1598
    • Bekeredjian, R.1    Kroll, R.D.2    Fein, E.3
  • 100
    • 34147197890 scopus 로고    scopus 로고
    • Enhancement of vascular permeability with low-frequency contrast-enhanced ultrasound in the chorioallantoic membrane model
    • Stieger SM, Caskey CF, Adamson RH, et al. Enhancement of vascular permeability with low-frequency contrast-enhanced ultrasound in the chorioallantoic membrane model. Radiology 2007;243:112-21
    • (2007) Radiology , vol.243 , pp. 112-121
    • Stieger, S.M.1    Caskey, C.F.2    Adamson, R.H.3
  • 101
    • 39749084633 scopus 로고    scopus 로고
    • Inhibition of melanoma by ultrasound-microbubble-aided drug delivery suggests membrane permeabilization
    • Sonoda S, Tachibana K, Uchino E, et al. Inhibition of melanoma by ultrasound-microbubble-aided drug delivery suggests membrane permeabilization. Cancer Biol Ther 2007;6:1276-83
    • (2007) Cancer Biol Ther , vol.6 , pp. 1276-1283
    • Sonoda, S.1    Tachibana, K.2    Uchino, E.3
  • 102
    • 5444243992 scopus 로고    scopus 로고
    • Development of efficient plasmid DNA transfer into adult rat central nervous system using microbubble-enhanced ultrasound
    • Shimamura M, Saro N, Taniyama Y, et al. Development of efficient plasmid DNA transfer into adult rat central nervous system using microbubble-enhanced ultrasound. Gene Ther 2004;11:1532-9
    • (2004) Gene Ther , vol.11 , pp. 1532-1539
    • Shimamura, M.1    Saro, N.2    Taniyama, Y.3
  • 103
    • 27944474332 scopus 로고    scopus 로고
    • Gene transfer into adult rat spinal com using naked plasmid DNA and ultrasound microbubbles
    • Shimamura M, Sato N, Taniyama Y, et al. Gene transfer into adult rat spinal com using naked plasmid DNA and ultrasound microbubbles. J Gene Med 2005;7:1468-74
    • (2005) J Gene Med , vol.7 , pp. 1468-1474
    • Shimamura, M.1    Sato, N.2    Taniyama, Y.3
  • 104
    • 33846484827 scopus 로고    scopus 로고
    • Takahashi M, Kido K, Aoi A, et al. Spinal gene transfer using ultrasound and microbubbles. J Control Release 2007;117:267-72
    • Takahashi M, Kido K, Aoi A, et al. Spinal gene transfer using ultrasound and microbubbles. J Control Release 2007;117:267-72
  • 105
    • 33644860216 scopus 로고    scopus 로고
    • Gene transfer to corneal epithelium and keratocytes mediated by ultrasound with microbubbles
    • Sonoda S, Tachibana K, Uchino E, et al. Gene transfer to corneal epithelium and keratocytes mediated by ultrasound with microbubbles. Invest Ophthalmol Vis Sci 2006;47:558-64
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 558-564
    • Sonoda, S.1    Tachibana, K.2    Uchino, E.3
  • 106
    • 36448984350 scopus 로고    scopus 로고
    • A novel bubble liposome and ultrasound-mediated gene transfer to ocular surface: RC-1 cells in vitro and conjunctiva in vivo
    • Yamashita T, Sonoda S, Suzuki R, et al. A novel bubble liposome and ultrasound-mediated gene transfer to ocular surface: RC-1 cells in vitro and conjunctiva in vivo. Exp Eye Res 2007;85:741-8
    • (2007) Exp Eye Res , vol.85 , pp. 741-748
    • Yamashita, T.1    Sonoda, S.2    Suzuki, R.3
  • 107
    • 48049096230 scopus 로고    scopus 로고
    • Ultrasound with microbubbles enhances gene expression of plasmid DNA in the liver via intraportal delivery
    • Shen ZP, Brayman AA, Chen L, et al. Ultrasound with microbubbles enhances gene expression of plasmid DNA in the liver via intraportal delivery. Gene Ther 2008;15:1147-55
    • (2008) Gene Ther , vol.15 , pp. 1147-1155
    • Shen, Z.P.1    Brayman, A.A.2    Chen, L.3
  • 108
    • 33745111263 scopus 로고    scopus 로고
    • Sustained transgene expression in intervertebral disc cells in vivo mediated by microbubble-enhanced ultrasound gene therapy
    • Nishida K, Doita M, Takada T, et al. Sustained transgene expression in intervertebral disc cells in vivo mediated by microbubble-enhanced ultrasound gene therapy. Spine 2006;31:1415-9
    • (2006) Spine , vol.31 , pp. 1415-1419
    • Nishida, K.1    Doita, M.2    Takada, T.3
  • 109
    • 12744278106 scopus 로고    scopus 로고
    • An efficient gene transfer method mediated by ultrasound and microbubbles into the kidney
    • Koike H, Tomita N, Azuma H, et al. An efficient gene transfer method mediated by ultrasound and microbubbles into the kidney. J Gene Med 2005;7:108-16
    • (2005) J Gene Med , vol.7 , pp. 108-116
    • Koike, H.1    Tomita, N.2    Azuma, H.3
  • 110
    • 36949024942 scopus 로고    scopus 로고
    • Ultrasound-contrast agent mediated naked gene delivery in the peritoneal cavity of adult rat
    • Guo H, Leung JC, Chan LY, et al. Ultrasound-contrast agent mediated naked gene delivery in the peritoneal cavity of adult rat. Gene Ther 2007;14:1712-20
    • (2007) Gene Ther , vol.14 , pp. 1712-1720
    • Guo, H.1    Leung, J.C.2    Chan, L.Y.3
  • 111
    • 34247110877 scopus 로고    scopus 로고
    • Use of ultrasound to enhance nonviral lung gene transfer in vivo
    • Xenariou S, Griesenbach U, Liang HD, et al. Use of ultrasound to enhance nonviral lung gene transfer in vivo. Gene Ther 2007;14:768-74
    • (2007) Gene Ther , vol.14 , pp. 768-774
    • Xenariou, S.1    Griesenbach, U.2    Liang, H.D.3
  • 112
    • 34249895264 scopus 로고    scopus 로고
    • Smad7 gene therapy ameliorates an autoimmune crescentic glomerulonephritis in mice
    • Ka SM, Huang XR, Lan HY, et al. Smad7 gene therapy ameliorates an autoimmune crescentic glomerulonephritis in mice. J Am Soc Nephrol 2007;18:1777-88
    • (2007) J Am Soc Nephrol , vol.18 , pp. 1777-1788
    • Ka, S.M.1    Huang, X.R.2    Lan, H.Y.3
  • 113
    • 34447100368 scopus 로고    scopus 로고
    • Reversal of streptozotocin-induced diabetes in rats by gene therapy with betacellulin and pancreatic duodenal homeobox-1
    • Chen S, Ding J, Yu C, et al. Reversal of streptozotocin-induced diabetes in rats by gene therapy with betacellulin and pancreatic duodenal homeobox-1. Gene Ther 2007;14:1102-10
    • (2007) Gene Ther , vol.14 , pp. 1102-1110
    • Chen, S.1    Ding, J.2    Yu, C.3
  • 114
    • 0036518709 scopus 로고    scopus 로고
    • Ultrasound-mediated transfection of canine myocardium by intravenous administration of cadonic microbubble-linked plasmid DNA
    • Vannan M, McCreery T, Li P, et al. Ultrasound-mediated transfection of canine myocardium by intravenous administration of cadonic microbubble-linked plasmid DNA. J Am Soc Echocardiogr 2002;15:214-8
    • (2002) J Am Soc Echocardiogr , vol.15 , pp. 214-218
    • Vannan, M.1    McCreery, T.2    Li, P.3
  • 115
    • 0037022843 scopus 로고    scopus 로고
    • Vascular gene transfer of phosphomimetic endothelial nitric oxide synthase (S1177D) using ultrasound-enhanced destruction of plasmid-loaded microbubbles improves vasoreactivity
    • Teupe C, Richter S, Fisslthaler B, et al. Vascular gene transfer of phosphomimetic endothelial nitric oxide synthase (S1177D) using ultrasound-enhanced destruction of plasmid-loaded microbubbles improves vasoreactivity. Circulation 2002;105:1104-9
    • (2002) Circulation , vol.105 , pp. 1104-1109
    • Teupe, C.1    Richter, S.2    Fisslthaler, B.3
  • 116
    • 0038826285 scopus 로고    scopus 로고
    • Optimization of ultrasound parameters for cardiac gene delivery of adenoviral or plasmid deoxyribonucleic acid by ultrasound-targeted microbubble destruction
    • Chen S, Shohet RV, Bekeredjian R, et al. Optimization of ultrasound parameters for cardiac gene delivery of adenoviral or plasmid deoxyribonucleic acid by ultrasound-targeted microbubble destruction. J Am Coll Cardiol 2003;42:30 1-8
    • (2003) J Am Coll Cardiol , vol.42 , Issue.30 , pp. 1-8
    • Chen, S.1    Shohet, R.V.2    Bekeredjian, R.3
  • 117
    • 0041857832 scopus 로고    scopus 로고
    • Ultrasound-targeted microbubble destruction can repeatedly direct highly specific plasmid expression to the heart
    • Bekeredjian R, Chen S, Frenkel PA, et al. Ultrasound-targeted microbubble destruction can repeatedly direct highly specific plasmid expression to the heart. Circulation 2003;108:1022-6
    • (2003) Circulation , vol.108 , pp. 1022-1026
    • Bekeredjian, R.1    Chen, S.2    Frenkel, P.A.3
  • 118
    • 0141426729 scopus 로고    scopus 로고
    • Optimization of ultrasound-mediated gene transfer: Comparison of contrast agents and ultrasound modalities
    • Pislaru SV, Pislaru C, Kinnick RR, et al. Optimization of ultrasound-mediated gene transfer: comparison of contrast agents and ultrasound modalities. Eur Heart J 2003;24:1690-8
    • (2003) Eur Heart J , vol.24 , pp. 1690-1698
    • Pislaru, S.V.1    Pislaru, C.2    Kinnick, R.R.3
  • 119
    • 0345862002 scopus 로고    scopus 로고
    • Targeted tissue transfection with ultrasound destruction of plasmid-bearing cationic microbubbles
    • Christiansen JP, French BA, Klibanov AL, et al. Targeted tissue transfection with ultrasound destruction of plasmid-bearing cationic microbubbles. Ultrasound Med Biol 2003;29:1759-67
    • (2003) Ultrasound Med Biol , vol.29 , pp. 1759-1767
    • Christiansen, J.P.1    French, B.A.2    Klibanov, A.L.3
  • 120
    • 0142210080 scopus 로고    scopus 로고
    • Gene transfer with echo-enhanced contrast agents: Comparison between Albunex, Optison, and Levovist in mice - initial results
    • Li T, Tachibana K, Kuroki M. Gene transfer with echo-enhanced contrast agents: comparison between Albunex, Optison, and Levovist in mice - initial results. Radiology 2003;229:423-8
    • (2003) Radiology , vol.229 , pp. 423-428
    • Li, T.1    Tachibana, K.2    Kuroki, M.3
  • 121
    • 0037344590 scopus 로고    scopus 로고
    • Microbubble ultrasound improves the efficiency of gene transduction in skeletal muscle in vivo with reduced tissue damage
    • Lu QL, Liang HD, Partridge T, et al. Microbubble ultrasound improves the efficiency of gene transduction in skeletal muscle in vivo with reduced tissue damage. Gene Ther 2003;10:396-405
    • (2003) Gene Ther , vol.10 , pp. 396-405
    • Lu, Q.L.1    Liang, H.D.2    Partridge, T.3
  • 122
    • 0037215799 scopus 로고    scopus 로고
    • Ultrasound-targeted antisense oligonucleotide attenuates ischemia/reperfusion-induced myocardial tumor necrosis factor-alpha
    • Erikson JM, Freeman GL, Chandrasekar B. Ultrasound-targeted antisense oligonucleotide attenuates ischemia/reperfusion-induced myocardial tumor necrosis factor-alpha. J Mol Cell Cardiol 2003;35:119-30
    • (2003) J Mol Cell Cardiol , vol.35 , pp. 119-130
    • Erikson, J.M.1    Freeman, G.L.2    Chandrasekar, B.3
  • 123
    • 15444362100 scopus 로고    scopus 로고
    • Ultrasound/microbubble enhances foreign gene expression in ECV304 cells and murine myocardium
    • Guo DP, Li XY, Sun P, et al. Ultrasound/microbubble enhances foreign gene expression in ECV304 cells and murine myocardium. Acta Biochim Biophys Sin (Shanghai) 2004;36:824-31
    • (2004) Acta Biochim Biophys Sin (Shanghai) , vol.36 , pp. 824-831
    • Guo, D.P.1    Li, X.Y.2    Sun, P.3
  • 124
    • 24344442393 scopus 로고    scopus 로고
    • Sonoporation using microbubble BR14 promotes pDNA/siRNA transduction to murine heart
    • Tsunoda S, Mazda O, Oda Y, et al. Sonoporation using microbubble BR14 promotes pDNA/siRNA transduction to murine heart. Biochem Biophys Res Commun 2005;336:118-27
    • (2005) Biochem Biophys Res Commun , vol.336 , pp. 118-127
    • Tsunoda, S.1    Mazda, O.2    Oda, Y.3
  • 125
    • 25144497498 scopus 로고    scopus 로고
    • Gene transfer with microbubble ultrasound and plasmid DNA into skeleral muscle of mice: Comparison between commercially available microbubble contrast agents
    • Wang X, Liang HD, Dong B, et al. Gene transfer with microbubble ultrasound and plasmid DNA into skeleral muscle of mice: comparison between commercially available microbubble contrast agents. Radiology 2005;237:224-9
    • (2005) Radiology , vol.237 , pp. 224-229
    • Wang, X.1    Liang, H.D.2    Dong, B.3
  • 126
    • 22744456826 scopus 로고    scopus 로고
    • Ultrasound-mediated delivery of TIMP-3 plasmid DNA into saphenous vein leads to increased lumen size in a porcine interposition graft model
    • Akowuah EF, Gray C, Lawrie A, et al. Ultrasound-mediated delivery of TIMP-3 plasmid DNA into saphenous vein leads to increased lumen size in a porcine interposition graft model. Gene Ther 2005;12:1154-7
    • (2005) Gene Ther , vol.12 , pp. 1154-1157
    • Akowuah, E.F.1    Gray, C.2    Lawrie, A.3
  • 127
    • 23644462711 scopus 로고    scopus 로고
    • Microbubble-enhanced ultrasound exposure promotes uptake of methotrexate into synovial cells and enhanced anti-inflammatory effects in the knees of rabbits with antigen-induced arthritis
    • Nakaya H, Shimizu T, Isobe K, et al. Microbubble-enhanced ultrasound exposure promotes uptake of methotrexate into synovial cells and enhanced anti-inflammatory effects in the knees of rabbits with antigen-induced arthritis. Arthritis Rheum 2005;52:2559-66
    • (2005) Arthritis Rheum , vol.52 , pp. 2559-2566
    • Nakaya, H.1    Shimizu, T.2    Isobe, K.3
  • 128
    • 22144476852 scopus 로고    scopus 로고
    • Ultrasound enhances gene delivery of human factor IX plasmid
    • Miao CH, Brayman AA, Loeb KR, et al. Ultrasound enhances gene delivery of human factor IX plasmid. Hum Gene Ther 2005;16:893-905
    • (2005) Hum Gene Ther , vol.16 , pp. 893-905
    • Miao, C.H.1    Brayman, A.A.2    Loeb, K.R.3
  • 129
    • 43049116901 scopus 로고    scopus 로고
    • Herpes simplex virus thymidine kinase-mediated suicide gene therapy using nano/microbubbles and ultrasound
    • Aoi A, Watanabe Y, Mori S, et al. Herpes simplex virus thymidine kinase-mediated suicide gene therapy using nano/microbubbles and ultrasound. Ultrasound Med Biol 2008;34:425-34
    • (2008) Ultrasound Med Biol , vol.34 , pp. 425-434
    • Aoi, A.1    Watanabe, Y.2    Mori, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.