Myocardial contrast echocardiography: Reliable, safe, and efficacious myocardial perfusion assessment after intravenous injections of a new echocardiographic contrast agent

American Heart Journal

Volumn 132, Issue 4, 1996, Pages 871-881

  Meza, Mario ^a   Greener, Yigal ^b   Hunt, Roberta ^b   Perry, Bret ^a   Revall, Susan ^a   Barbee, Wayne ^a   Murgo, Joseph P ^a   Cheirif, Jorge ^a,c  

^a OCHSNER MEDICAL CENTER   (United States)

^b Dept Preclin Studs Molec B ^*  (United States)

^c OCHSNER CLINIC FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONTRAST MEDIUM; DOBUTAMINE; FS 609; OCTAFLUOROPROPANE; TRIPHENYLTETRAZOLIUM; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTICLE; CONTRAST ECHOCARDIOGRAPHY; CONTROLLED STUDY; DOG; HEART HEMODYNAMICS; HEART MUSCLE BLOOD FLOW; HEART MUSCLE NECROSIS; HEART MUSCLE PERFUSION; HYPEREMIA; INTRAVENOUS DRUG ADMINISTRATION; LUNG ARTERY PRESSURE; NONHUMAN; OXYGEN SATURATION; PRIORITY JOURNAL;

EID: 0029956720     PISSN: 00028703     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-8703(96)90324-5     Document Type: Article

References (35)

1. Feinstein S, Lang R, Dick C, Neumann A, Al-Sadir J, Chua KG, Carroll J, Feldman T, Borow KM. Contrast echocardiography during coronary arteriography in humans: perfusion and anatomic studies. J Am Coll Cardiol 1988;11:59-65.
2. Armstrong W, Mueller T, Kinney E, Tichner E, Dillon J, Feigenbaum H. Assessment of myocardial perfusion abnormalities with contrast-enhanced two-dimensional echocardiography. Circulation 1982;66:166-73.
3. Kemper A, O'Boyle J, Cohen CA, Taylor A, Parisi AF. Hydrogen peroxide contrast echocardiography: quantification in vivo of myocardial risk area during coronary occlusion and the necrotic area remaining after myocardial reperfusion. Circulation 1983;70:309-17.
4. Ten Cate J, Drury J, Meerbaum S, Noordsy J, Feinstein S, Shah P, Corday E. Myocardial contrast two-dimensional echocardiography: experimental examination at different coronary flow levels. J Am Coll Cardiol 1984;3:1219-26.
5. Ten Cate FJ, Silverman PR, Cornell JH, Serruys PW, Roelandt JRTC. Myocardial contrast echocardiography during hyperemia. Coron Artery Dis 1990;1:573-8.
6. Cheirif J, Zoghbi WA, Raizner AE, Minor ST, Winters WL, Klein MS, DeBauche TL, Lewis JM, Roberts R, Quinones MA. Assessment of myocardial perfusion in humans by contrast echocardiography, I. Evaluation of regional coronary reserve by peak contrast intensity. J Am Coll Cardiol 1988;11:735-43.
7. Cheirif J, Zoghbi WA, Bolli R, O'Neill PG, Hoyt BD, Quiñones MA. Assessment of regional myocardial perfusion by contrast echocardiography. II. Detection of changes in transmural and subendocardial perfusion during dipyridamole-induced hyperemia in a model of critical coronary stenosis. J Am Coll Cardiol 1989;14:1555-65.
8. Desir RM, Cheirif JB, Bolli R, Zoghbi WA, Hoyt BD, Quinones MA. Assessment of regional myocardial perfusion with myocardial contrast echocardiography in a canine model of varying degrees of coronary stenosis. Am Heart J 1994;127:56-63.
9. Vandenberg B, Feinstein S, Kieso R, Hunt M, Kerber R. Myocardial risk area and peak gray level measurement by contrast echocardiography: effect of microbubble size and concentration, injection rate and coronary vasodilation. Am Heart J 1988;115:733-9.
10. Porter TR, D'Sa A, Turner C, Jones LA, Minisi AJ, Mohanty PK, Ventrovec GW, Nixon JV. Myocardial contrast echocardiography for the assessment of coronary blood flow reserve: validation in humans. J Am Coll Cardiol 1993;21:349-55.
11. Grill HP, Brinker JA, Taube JC, Walford GD, Midei MG, Flaherty JT, Weiss JL. Contrast echocardiographic mapping of collateralized myocardium in humans before and after coronary angioplasty. J Am Coll Cardiol 1990;16:1594-600.
12. Lang R, Feinstein S, Feldman T, Neumann A, Chau K, Borow D. Contrast echocardiography for evaluation of myocardial perfusion: effects of coronary angioplasty. J Am Coll Cardiol 1986;8:232-5.
13. Aronson S. Intraoperative contrast echocardiography: assessment of the adequacy of revascularization during CABG surgery. Am J Card Imaging 1991;5:224-9.
14. Lim Y-J, Nanto S, Masuyama T, Kodama K, Kohama A, Kitabatake A, Kamada T. Coronary collaterals assessed with myocardial contrast echocardiography in healed myocardial infarction. Am J Cardiol 1990; 66:556-61.
15. Sabia PJ, Powers ER, Jayaweera AR, Ragosta M, Kaul S. Functional significance of collateral blood flow in patients with recent acute myocardial infarction: a study using myocardial contrast echocardiography. Circulation 1992;85:2080-9.
16. Ito H, Tomooka T, Sakai N, Yu H, Higashino Y, Fujii K, Masuyama T, Kitabatake A, Minamino T. Lack of myocardial perfusion immediately after successful thrombolysis: a predictor of poor recovery of left ventricular function in anterior myocardial infarction. Circulation 1992; 85:1699-705.
17. Ten Cate F, Feinstein S, Zwehl W. Two-dimensional contrast echocardiography. II. Transpulmonary studies. J Am Coll Cardiol 1984;3:21-7.
18. Berwing K, Schlepper M. Echocardiographic imaging of the left ventricle by peripheral intravenous injection of echo contrast agent. Am Heart J 1988;115:399-408.
19. Smith M, Elion J, McClure R, Kwan O, DeMaria A. Left heart opacification with peripheral venous injection of new saccharide echo contrast agent in dogs. J Am Coll Cardiol 1989;13:1622-8.
20. Feinstein S, Cheirif J, Ten Cate F, Silverman P, Heidenreich P, Dick C, Desir R, Armstrong W, Quiñones M, Shah P. Safety and efficacy of a new transpulmonary ultrasound contrast agent: initial multicenter clinical results. J Am Coll Cardiol 1990;16:316-24.
21. Crouse LJ, Cheirif J, Hanly DE, Kisslo JA, Labovitz AJ, Raichlen JS, Schutz RW, Shah PM, Smith MD. Opacification and border delineation improvement in patients with suboptimal endocardial border definition in routine echocardiography: results of the Phase III Albunex Multicenter Trial. J Am Coll Cardiol 1993;22:1494-500.
22. Sanders WE, Cheirif J, Desir R, Zoghbi WA, Hoyt BD, Schulz PE, Quiñones MA. Contrast opacification of left ventricular myocardium following intravenous administration of sonicated albumin microspheres. Am Heart J 1991;122:1660-5.
23. Wilson B, Shung KK, Hete B, Levene H, Barnhart JL. A feasibility study on quantitating myocardial perfusion with Albunex, an ultrasonic contrast agent. Ultrasound Med Biol 1993;19:181-91.
24. Porter TR, Xie F. Visually discernible myocardial echocardiographic contrast after intravenous injection of sonicated dextrose albumin microbubbles containing high molecular weight, less soluble gases. J Am Coll Cardiol 1995;25:509-15.
25. Villanueva FS, Glasheen WP, Sklenar J, Kaul S. Assessment of risk area during coronary occlusion and infarct size after reperfusion with myocardial contrast echocardiography using left and right atrial injection of contrast. Circulation 1993;88:596-604.
26. Meza M, Greener Y, Perry B, Hunt R, Bales G, Revall S, Murgo JP, Cheirif J. Myocardial contrast echocardiography: successful transpulmonary myocardial opacification in a canine model of occlusion-reperfusion. J Am Soc Echocardiogr 1994;7:S2.
27. Meza M, Greener Y, Aristizabal D, Perry B, Hunt R, Revall S, Murgo JP, Cheirif J. Myocardial contrast echocardiography safety of FS069, a new transpulmonary echocardiographic contrast agent. J Am Soc Echocardiogr 1994;7:S36.
28. Dittrich H, Bales G, Kuvelas T, Hunt R, McFerran B, Greener Y. Myocardial contrast echocardiography in experimental coronary artery occlusion with a new intravenously administered contrast agent. J Am Soc Echocardiogr 1995;8:465-74.
29. Xie F, Porter TR. Acute myocardial ischemia and reperfusion can be visually identified non-invasively with intravenous perfluoropropane-enhanced sonicated albumin ultrasound contrast. Circulation 1994; 90:1-555.
30. Grayburn PA, Erikson JM, Velasco CE. Assessment of myocardial risk area and infarct size by peripheral intravenous injection of a new phase-shift echo contrast agent. Circulation 1994;90:I-555.
31. Grauer S, Panteli GA, Xu J, Shiota T, Gong Z, Giraud GG, Relier MD, Sahn DJ. Aerosomes MRX 115: Echocardiographic and hemodynamic characteristics of a new echo contrast agent that produces myocardial opacification after intravenous injection in pigs. Circulation 1994;90:I-556.
32. Cheirif J, Narkiewitz-Jodko J, Bravenec J, D'Sa A, Quinones M, Mickelson J. Myocardial contrast echocardiography relation between on-line and off-line assessment of myocardial perfusion. Echocardiography 1993;10:471-84.
33. Cheirif J, Desir RM, Bolli R, Mahmarian JJ, Zoghbi WA, Verani MS, Quiñones MA. Relation of perfusion defects observed with myocardial contrast echocardiography to the severity of coronary stenosis: correlation with thallium-201 single photon emission tomography. J Am Coll Cardiol 1992;19:1343-9.
34. Quiñones MA, Pickering E, Alexander JK. Percentage of shortening of the echocardiographic left ventricular dimension. Its use in determining ejection fraction and stroke volume. Chest 1978;74:59-65.
35. Bassingthwaighte JB. Physiology and theory or tracer washout techniques for the estimation of myocardial blood flow: flow estimation from tracer washout. Prog Cardiovasc Dis 1977;20:165-88.