Vascular gene transfer of phosphomimetic endothelial nitric oxide synthase (S1177D) using ultrasound-enhanced destruction of plasmid-loaded microbubbles improves vasoreactivity

Circulation

Volumn 105, Issue 9, 2002, Pages 1104-1109

  Teupe, Claudius ^a   Richter, Sergio ^a   Fisslthaler, Beate ^a   Randriamboavonjy, Voahanginirina ^a   Ihling, Christian ^a   Fleming, Ingrid ^a   Busse, Rudi ^a   Zeiher, Andreas M ^a   Dimmeler, Stefanie ^a  

^a GOETHE UNIVERSITY   (Germany)

Author keywords

Echocardiography; Endothelium; Gene therapy; Nitric oxide synthase

Indexed keywords

ALBUMIN; ASPARTIC ACID; BRADYKININ; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; PLASMID DNA; PROSTAGLANDIN F2 ALPHA; SERINE;

ANIMAL TISSUE; ARTICLE; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; CORONARY ARTERY; ENDOTHELIUM CELL; GENE DELIVERY SYSTEM; GENE TRANSFER; GENETIC CODE; GENETIC TRANSFECTION; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION; SWINE; ULTRASOUND; WESTERN BLOTTING;

AMINO ACID SUBSTITUTION; ANIMALS; BETA-GALACTOSIDASE; BLOTTING, WESTERN; CORONARY VESSELS; DINOPROST; DRUG DELIVERY SYSTEMS; ECHOCARDIOGRAPHY; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; FEASIBILITY STUDIES; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENES, REPORTER; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE III; PLASMIDS; SERUM ALBUMIN; SONICATION; SWINE; TRANSFECTION; ULTRASONOGRAPHY, INTERVENTIONAL; VASOMOTOR SYSTEM;

EID: 0037022843     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/hc0902.104720     Document Type: Article

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