Spatio-temporal analysis of molecular delivery through the blood-brain barrier using focused ultrasound

Physics in Medicine and Biology

Volumn 52, Issue 18, 2007, Pages 5509-5530

  Choi, J J ^a   Pernot, M ^a   Brown, T R ^a,b   Small, S A ^b   Konofagou, E E ^a,b  

^a Columbia University ^*  (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; BRAIN; DEPOSITION; DRUG DELIVERY; GADOLINIUM;

BLOOD-BRAIN BARRIER (BBB) OPENINGS; MOLECULAR DELIVERY; THERMAL DEPOSITION SIMULATIONS;

ULTRASONIC IMAGING;

FS 069; GADODIAMIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN BLOOD VESSEL; BRAIN REGION; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG DOSE REDUCTION; EX VIVO STUDY; HIPPOCAMPUS; IN VITRO STUDY; IN VIVO STUDY; INJECTION SITE; MALE; MICROBUBBLE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; SIMULATION; TEMPERATURE; TISSUE DISTRIBUTION; ULTRASOUND;

ALBUMINS; ANIMALS; BLOOD-BRAIN BARRIER; COMPUTER SIMULATION; DRUG DELIVERY SYSTEMS; FEMALE; FLUOROCARBONS; GADOLINIUM; HIPPOCAMPUS; MALE; METABOLIC CLEARANCE RATE; MICE; MICE, INBRED C57BL; MODELS, BIOLOGICAL; SONICATION; TISSUE DISTRIBUTION;

EID: 35848934576     PISSN: 00319155     EISSN: 13616560     Source Type: Journal    
DOI: 10.1088/0031-9155/52/18/004     Document Type: Article

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