Distribution of orexin/hypocretin in the rat median eminence and pituitary

Molecular Brain Research

Volumn 76, Issue 1, 2000, Pages 1-6

  Date, Yukari ^a,b   Mondal, Muhtashan S ^a   Matsukura, Shigeru ^a   Ueta, Yoichi ^c   Yamashita, Hiroshi ^c   Kaiya, Hiroyuki ^b   Kangawa, Kenji ^b   Nakazato, Masamitsu ^a  

^a UNIVERSITY OF MIYAZAKI   (Japan)

^b NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^c UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

Author keywords

Hypocretin; Immunohistochemistry; In situ hybridization; Orexin; Orexin receptor; Pituitary

Indexed keywords

MESSENGER RNA; OREXIN; OREXIN A; OREXIN B; RECEPTOR;

ADENOHYPOPHYSIS; ANIMAL TISSUE; ARTICLE; HYPOPHYSIS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MEDIAN EMINENCE; NEUROHYPOPHYSIS; NONHUMAN; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE DISTRIBUTION;

ANIMALS; CARRIER PROTEINS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MEDIAN EMINENCE; NEUROPEPTIDES; PITUITARY GLAND; RABBITS; RADIOIMMUNOASSAY; RATS; RATS, WISTAR; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NEUROPEPTIDE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 0034629016     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(99)00317-4     Document Type: Article

References (13)

1. Bernardis L.L., Bellinger L.L. The lateral hypothalamic area revisited: ingestive behavior. Neurosci. Biobehav. Rev. 20:1996;189-287.
2. Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:1987;156-159.
3. Date Y., Ueta Y., Yamashita H., Yamaguchi H., Matsukura S., Kangawa K., Sakurai T., Yanagisawa M., Nakazato M. Orexins, orexigenic hypothalamic peptides, interact with autonomic, neuroendocrine and neuroregulatory systems. Proc. Natl. Acad. Sci. U. S. A. 96:1999;748-753.
4. De Lecea L., Kilduff T.S., Peyron C., Gao X.-B., Foye P.E., Danielson P.E., Fukuhara C., Battenberg E.L.F., Gautvik V.T., Bartlett II F.S., Frankel W.N., Van den Pol A.N., Bloom F.E., Gautvik K.M., Sutcliffe J.G. The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity. Proc. Natl. Acad. Sci. U. S. A. 95:1998;322-327.
5. Mondal M.S., Nakazato M., Date Y., Murakami N., Yanagisawa M., Matsukura S. Widespread distribution of orexin in rat brain and its regulation upon fasting. Biochem. Biophys. Res. Commun. 256:1999;495-499.
6. Nambu T., Sakurai T., Mizukami K., Hosoya Y., Yanagisawa M., Goto K. Distribution of orexin neurons in the adult rat brain. Brain Res. 827:1999;243-260.
7. Peyron C., Tighe D.K., Van den Pol A.N., De Lecea L., Heller H.C., Sutcliffe J.G., Kilduff T.S. Neurons containing hypocretin (orexin) project to multiple neuronal systems. J. Neurosci. 18:1998;9996-10015.
8. Pu S., Jain M.R., Kalra P.S., Kalra S.P. Orexins, a novel family of hypothalamic neuropeptides, modulate pituitary luteinizing hormone secretion in an ovarian steroid-dependent manner. Regul. Pept. 78:1998;133-136.
9. Sakurai T., Amemiya A., Ishii M., Matsuzaki I., Chemelli R.M., Tanaka H., Williams S.C., Richardson J.A., Kozlowski G.P., Wilson S., Arch J.R.S., Buckingham R.E., Haynes A.C., Carr S.A., Annan R.S., McNulty D.E., Liu W-S., Terrett J.A., Elshourbagy N.A., Bergsma D.J., Yanagisawa M. Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell. 92:1998;573-585.
10. Samson W.K., Gosnell B., Chang J.-K., Resch Z.T., Murphy T.C. Cardiovascular regulatory actions of the hypocretins in brain. Brain Res. 831:1999;248-253.
11. L.W. Swanson, The hypothalamus, in: A. Bjorklund, T. Hökfelt, L.W. Swanson (Eds.), Handbook of Chemical Neuroanatomy, Elsevier, New York, 1987, pp. 1-124.
12. Trivedi P., Yu H., MacNeil D.J., Van der Ploeg L.H.T., Guan X.-M. Distribution of orexin receptor mRNA in the rat brain. FEBS Lett. 438:1998;71-75.
13. Ueta Y., Levy A., Chowdrey H.S., Lightman S.L. Hypothalamic nitric oxide synthase gene expression is regulated by thyroid hormones. Endocrinology. 136:1995;4182-4187.