Antiatherosclerotic effects of a novel synthetic tissue-selective steroidal liver X receptor agonist in low-density lipoprotein receptor-deficient mice

Journal of Pharmacology and Experimental Therapeutics

Volumn 327, Issue 2, 2008, Pages 332-342

  Peng, Dacheng ^a   Hiipakka, Richard A ^a   Dai, Qing ^a   Guo, Jian ^c   Reardon, Catherine A ^b   Getz, Godfrey S ^b   Liao, Shutsung ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3ALPHA,6ALPHA,24 TRIHYDROXY 24,24 DI(TRIFLUOROMETHYL) 5BETA CHOLANE; ABC TRANSPORTER A1; ATI 829; DRUG VEHICLE; LIVER X RECEPTOR AGONIST; LOW DENSITY LIPOPROTEIN RECEPTOR; N (2,2,2 TRIFLUOROETHYL) N [4 [2,2,2 TRIFLUORO 1 HYDROXY 1 (TRIFLUOROMETHOXY)ETHYL]PHENYL]BENZENESULFONAMIDE; STEROL REGULATORY ELEMENT BINDING PROTEIN; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA ROOT; ARTICLE; ATHEROSCLEROSIS; BRACHIOCEPHALIC TRUNK; CONTROLLED STUDY; DRUG EFFICACY; HEPATOMA CELL; HUMAN; HUMAN CELL; HYPERTRIGLYCERIDEMIA; HYPOBETALIPOPROTEINEMIA; LEFT CORONARY ARTERY; LIPOGENESIS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TISSUE SPECIFICITY; TRIACYLGLYCEROL BLOOD LEVEL;

ANIMALS; APOLIPOPROTEINS E; ATHEROSCLEROSIS; ATP-BINDING CASSETTE TRANSPORTERS; CELL LINE; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; HUMANS; HYDROXYSTEROIDS; LIPOPROTEINS; LIPOPROTEINS, LDL; LIPOPROTEINS, VLDL; MALE; MICE; MICE, INBRED C57BL; ORGAN SPECIFICITY; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, LDL; TRIGLYCERIDES;

EID: 54349097048     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.108.142687     Document Type: Article

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