메뉴 건너뛰기




Volumn 20, Issue 3, 2006, Pages 466-475

Calcium signaling stimulates translation of HIF-α during hypoxia

Author keywords

Carotid body; Oxygen sensitive cells; PC12 cells; Protein kinase C; Protein translation

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 12 (2 CYANOETHYL) 6,7,12,13 TETRAHYDRO 13 METHYL 5 OXOINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CALCIUM; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 1BETA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; IONOMYCIN; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN KINASE C ALPHA; PROTEIN KINASE C ALPHA INHIBITOR; RAPAMYCIN; 1,3 BUTADIENE DERIVATIVE; ARNT PROTEIN, RAT; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; BENZYLAMINE DERIVATIVE; CAPPED RNA; CARBAZOLE DERIVATIVE; CYCLOHEXIMIDE; FLAVONOID; HYPOXIA INDUCIBLE FACTOR 2, ALPHA SUBUNIT; HYPOXIA-INDUCIBLE FACTOR 2, ALPHA SUBUNIT; INDOLE DERIVATIVE; ISOQUINOLINE DERIVATIVE; KN 92; MESSENGER RNA; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; N [2 [[N [3 (4 CHLOROPHENYL) 2 PROPENYL] N METHYLAMINO]METHYL]PHENYL] N (2 HYDROXYETHYL) 4 METHOXYBENZENESULFONAMIDE; NITRILE; PROTEIN KINASE; PROTEIN SYNTHESIS INHIBITOR; SMALL INTERFERING RNA; SULFONAMIDE;

EID: 33645835678     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.05-5086com     Document Type: Article
Times cited : (121)

References (50)
  • 1
    • 0024477188 scopus 로고
    • PO2 chemoreception in arterial chemoreceptors
    • Acker, H. (1989) PO2 chemoreception in arterial chemoreceptors. Annu. Rev. Physiol. 51, 835-844
    • (1989) Annu. Rev. Physiol. , vol.51 , pp. 835-844
    • Acker, H.1
  • 2
    • 0033991530 scopus 로고    scopus 로고
    • Expression of hypoxia-inducible factor 1: Mechanisms and consequences
    • Semenza, G. L. (2000) Expression of hypoxia-inducible factor 1: mechanisms and consequences. Biochem. Pharmacol. 59, 47-53
    • (2000) Biochem. Pharmacol. , vol.59 , pp. 47-53
    • Semenza, G.L.1
  • 3
    • 0037307858 scopus 로고    scopus 로고
    • The von Hippel-Lindau tumor suppressor protein: New insights into oxygen sensing and cancer
    • Kim, W., and Kaelin, W. G., Jr. (2003) The von Hippel-Lindau tumor suppressor protein: new insights into oxygen sensing and cancer. Curr. Opin. Genet. Dev. 13, 55-60
    • (2003) Curr. Opin. Genet. Dev. , vol.13 , pp. 55-60
    • Kim, W.1    Kaelin Jr., W.G.2
  • 4
    • 0036000028 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1alpha mRNA contains an internal ribosome entry site that allows efficient translation during normoxia and hypoxia
    • Lang, K. J. D., Kappel, A., and Goodall, G. J. (2002) Hypoxia-inducible factor-1alpha mRNA contains an internal ribosome entry site that allows efficient translation during normoxia and hypoxia. Mol. Biol. Cell 13, 1792-1801
    • (2002) Mol. Biol. Cell , vol.13 , pp. 1792-1801
    • Lang, K.J.D.1    Kappel, A.2    Goodall, G.J.3
  • 5
    • 0034307483 scopus 로고    scopus 로고
    • Internal ribosome initiation of translation and the control of cell death
    • Holcik, M., Sonenberg, N., and Korneluk, R. G. (2000) Internal ribosome initiation of translation and the control of cell death. Trends Genet. 16, 469-473
    • (2000) Trends Genet. , vol.16 , pp. 469-473
    • Holcik, M.1    Sonenberg, N.2    Korneluk, R.G.3
  • 7
    • 0027979247 scopus 로고
    • Hypoxia increases rate of transcription and stability of tyrosine hydroxylase mRNA in pheochromocytoma (PC12) cells
    • Czyzyk-Krzeska, M. F., Furnari, B. A., Lawson, E. E., and Millhorn, D. E. (1994) Hypoxia increases rate of transcription and stability of tyrosine hydroxylase mRNA in pheochromocytoma (PC12) cells. J. Biol. Chem. 269, 760-764
    • (1994) J. Biol. Chem. , vol.269 , pp. 760-764
    • Czyzyk-Krzeska, M.F.1    Furnari, B.A.2    Lawson, E.E.3    Millhorn, D.E.4
  • 8
    • 0029758188 scopus 로고    scopus 로고
    • Membrane depolarization in PC-12 cells during hypoxia is regulated by an O2-sensitive K+ current
    • Zhu, W. H., Conforti, L., Czyzyk-Krzeska, M. F., and Millhorn, D. E. (1996) Membrane depolarization in PC-12 cells during hypoxia is regulated by an O2-sensitive K+ current. Am. J. Physiol. 271, C658-C665
    • (1996) Am. J. Physiol. , vol.271
    • Zhu, W.H.1    Conforti, L.2    Czyzyk-Krzeska, M.F.3    Millhorn, D.E.4
  • 9
    • 0030764438 scopus 로고    scopus 로고
    • Selective inhibition of a slow-inactivating voltage-dependent K+ channel in rat PC12 cells by hypoxia
    • Conforti, L., and Millhorn, D. E. (1997) Selective inhibition of a slow-inactivating voltage-dependent K+ channel in rat PC12 cells by hypoxia. J. Physiol. 502, 293-305
    • (1997) J. Physiol. , vol.502 , pp. 293-305
    • Conforti, L.1    Millhorn, D.E.2
  • 11
    • 0030968261 scopus 로고    scopus 로고
    • Hypoxia-induced catecholamine release and intracellular Ca2+ increase via suppression of K+ channels in cultured rat adrenal chromaffin cells
    • Mochizuki-Oda, N., Takeuchi, Y., Matsumura, K., Oosawa, Y., and Watanabe, Y. (1997) Hypoxia-induced catecholamine release and intracellular Ca2+ increase via suppression of K+ channels in cultured rat adrenal chromaffin cells. J. Neurochem. 69, 377-387
    • (1997) J. Neurochem. , vol.69 , pp. 377-387
    • Mochizuki-Oda, N.1    Takeuchi, Y.2    Matsumura, K.3    Oosawa, Y.4    Watanabe, Y.5
  • 13
    • 0026577610 scopus 로고
    • Regulation of tyrosine hydroxylase gene expression in the rat carotid body by hypoxia
    • Czyzyk-Krzeska, M. F., Bayliss, D. A., Lawson, E. E., and Millhorn, D. E. (1992) Regulation of tyrosine hydroxylase gene expression in the rat carotid body by hypoxia. J. Neurochem. 58, 1538-1546
    • (1992) J. Neurochem. , vol.58 , pp. 1538-1546
    • Czyzyk-Krzeska, M.F.1    Bayliss, D.A.2    Lawson, E.E.3    Millhorn, D.E.4
  • 14
    • 0037389490 scopus 로고    scopus 로고
    • Regulation of tyrosine hydroxylase promoter activity by the von Hippel-Lindau tumor suppressor protein and hypoxia-inducible transcription factors
    • Schnell, P. O., Ignacak, M. L., Bauer, A. L., Striet, J. B., Paulding, W. R., and Czyzyk-Krzeska, M. F. (2003) Regulation of tyrosine hydroxylase promoter activity by the von Hippel-Lindau tumor suppressor protein and hypoxia-inducible transcription factors. J. Neurochem. 85, 483-491
    • (2003) J. Neurochem. , vol.85 , pp. 483-491
    • Schnell, P.O.1    Ignacak, M.L.2    Bauer, A.L.3    Striet, J.B.4    Paulding, W.R.5    Czyzyk-Krzeska, M.F.6
  • 17
    • 7244242390 scopus 로고    scopus 로고
    • Chelation of cellular calcium modulates hypoxia-inducible gene expression through activation of hypoxia-inducible factor-1alpha
    • Berchner-Pfannschmidt, U., Petrat, F., Doege, K., Trinidad, B., Freitag, P., Metzen, E., de Groot, H., and Fandrey, J. (2004) Chelation of cellular calcium modulates hypoxia-inducible gene expression through activation of hypoxia-inducible factor-1alpha. J. Biol. Chem. 279, 44976-44986
    • (2004) J. Biol. Chem. , vol.279 , pp. 44976-44986
    • Berchner-Pfannschmidt, U.1    Petrat, F.2    Doege, K.3    Trinidad, B.4    Freitag, P.5    Metzen, E.6    De Groot, H.7    Fandrey, J.8
  • 18
    • 4043171462 scopus 로고    scopus 로고
    • Upstream and downstream of mTOR
    • Hay, N., and Sonenberg, N. (2004) Upstream and downstream of mTOR. Genes Dev. 18, 1926-1945
    • (2004) Genes Dev. , vol.18 , pp. 1926-1945
    • Hay, N.1    Sonenberg, N.2
  • 19
    • 0028207001 scopus 로고
    • Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family
    • Jefferies, H. B., Reinhard, C., Kozma, S. C., and Thomas, G. (1994) Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family. Proc. Natl. Acad. Sci. USA 91, 4441-4445
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 4441-4445
    • Jefferies, H.B.1    Reinhard, C.2    Kozma, S.C.3    Thomas, G.4
  • 20
    • 0042031047 scopus 로고    scopus 로고
    • A novel hypoxia-inducible factor-independent hypoxic response regulating mammalian target of rapamycin and its targets
    • Arsham, A. M., Howell, J. J., and Simon, M. C. (2003) A novel hypoxia-inducible factor-independent hypoxic response regulating mammalian target of rapamycin and its targets. J. Biol. Chem. 278, 29655-29660
    • (2003) J. Biol. Chem. , vol.278 , pp. 29655-29660
    • Arsham, A.M.1    Howell, J.J.2    Simon, M.C.3
  • 21
    • 0033062412 scopus 로고    scopus 로고
    • Hypoxia increases the association of 4E-binding protein 1 with the initiation factor 4E in isolated rat hepatocytes
    • Tinton, S. A., and Buc-Calderon, P. M. (1999) Hypoxia increases the association of 4E-binding protein 1 with the initiation factor 4E in isolated rat hepatocytes. FEBS Lett. 446, 55-59
    • (1999) FEBS Lett. , vol.446 , pp. 55-59
    • Tinton, S.A.1    Buc-Calderon, P.M.2
  • 22
    • 20544465985 scopus 로고    scopus 로고
    • Regulation of transcription and translation by hypoxia
    • Liu, L., and Simon, M. C. (2004) Regulation of transcription and translation by hypoxia. Cancer Biol. Ther. 3, 492-497
    • (2004) Cancer Biol. Ther. , vol.3 , pp. 492-497
    • Liu, L.1    Simon, M.C.2
  • 24
    • 0036855463 scopus 로고    scopus 로고
    • Protein kinase C alpha (PKC alpha): Regulation and biological function
    • Nakashima, S. (2002) Protein kinase C alpha (PKC alpha): regulation and biological function. J. Biochem. (Tokyo) 132, 669-675
    • (2002) J. Biochem. (Tokyo) , vol.132 , pp. 669-675
    • Nakashima, S.1
  • 25
    • 0001686632 scopus 로고    scopus 로고
    • Endogenous voltage-gated potassium channels in human embryonic kidney (HEK293) cells
    • Yu, S. P., and Kerchner, G. A. (1998) Endogenous voltage-gated potassium channels in human embryonic kidney (HEK293) cells. J. Neurosci. Res. 52, 612-617
    • (1998) J. Neurosci. Res. , vol.52 , pp. 612-617
    • Yu, S.P.1    Kerchner, G.A.2
  • 26
    • 0032101645 scopus 로고    scopus 로고
    • Identification of endogenous outward currents in the human embryonic kidney (HEK 293) cell line
    • Zhu, G., Zhang, Y., Xu, H., and Jiang, C. (1998) Identification of endogenous outward currents in the human embryonic kidney (HEK 293) cell line. J. Neurosci. Meth. 81, 73-83
    • (1998) J. Neurosci. Meth. , vol.81 , pp. 73-83
    • Zhu, G.1    Zhang, Y.2    Xu, H.3    Jiang, C.4
  • 27
    • 0036718436 scopus 로고    scopus 로고
    • Endogenous Kv channels in human embryonic kidney (HEK-293) cells
    • Jiang, B., Sun, X., Cao, K., and Wang, R. (2002) Endogenous Kv channels in human embryonic kidney (HEK-293) cells. Mol. Cell. Biochem. 238, 69-79
    • (2002) Mol. Cell. Biochem. , vol.238 , pp. 69-79
    • Jiang, B.1    Sun, X.2    Cao, K.3    Wang, R.4
  • 28
    • 3342915708 scopus 로고    scopus 로고
    • Intramembrane charge movement associated with endogenous K+ channel activity in HEK-293 cells
    • Avila, G., Sandoval, A., and Felix, R. (2004) Intramembrane charge movement associated with endogenous K+ channel activity in HEK-293 cells. Cell. Mol. Neurobiol. 24,317-330
    • (2004) Cell. Mol. Neurobiol. , vol.24 , pp. 317-330
    • Avila, G.1    Sandoval, A.2    Felix, R.3
  • 30
    • 0036618178 scopus 로고    scopus 로고
    • Preferential transformation of human neuronal cells by human adenoviruses and the origin of HEK 293 cells
    • Shaw, G., Morse, S., Ararat, M., and Graham, F. L. (2002) Preferential transformation of human neuronal cells by human adenoviruses and the origin of HEK 293 cells. FASEB J. 16, 869-871
    • (2002) FASEB J. , vol.16 , pp. 869-871
    • Shaw, G.1    Morse, S.2    Ararat, M.3    Graham, F.L.4
  • 31
    • 0033761629 scopus 로고    scopus 로고
    • Synthesis of the translational apparatus is regulated at the translational level
    • Mayuhas, O. (2000) Synthesis of the translational apparatus is regulated at the translational level. Eur. J. Biochem. 267, 6321-6330
    • (2000) Eur. J. Biochem. , vol.267 , pp. 6321-6330
    • Mayuhas, O.1
  • 32
    • 0032956850 scopus 로고    scopus 로고
    • p70(S6K) controls selective mRNA translation during oocyte maturation and early embryogenesis in Xenopus laevis
    • Schwab, M. S., Kim, S. H., Terada, N., Edfjall, C., Kozma, S. C., Thomas, G., and Maller, J. L. (1999) p70(S6K) controls selective mRNA translation during oocyte maturation and early embryogenesis in Xenopus laevis. Mol. Cell. Biol. 19, 2485-2494
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 2485-2494
    • Schwab, M.S.1    Kim, S.H.2    Terada, N.3    Edfjall, C.4    Kozma, S.C.5    Thomas, G.6    Maller, J.L.7
  • 33
    • 0033772338 scopus 로고    scopus 로고
    • An encore for ribosome biogenesis in the control of cell proliferation
    • Thomas, G. (2000) An encore for ribosome biogenesis in the control of cell proliferation. Nat. Cell Biol. 2, E71-E72
    • (2000) Nat. Cell Biol. , vol.2
    • Thomas, G.1
  • 34
    • 0032834055 scopus 로고    scopus 로고
    • eIF4 initiation factors: Effectors of mRNA recruitment to ribosomes and regulators of translation
    • Gingras, A. C., Raught, B., and Sonenberg, N. (1999) eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation. Annu. Rev. Biochem. 68, 913-963
    • (1999) Annu. Rev. Biochem. , vol.68 , pp. 913-963
    • Gingras, A.C.1    Raught, B.2    Sonenberg, N.3
  • 36
    • 19444372601 scopus 로고    scopus 로고
    • Protein kinase Calpha modulates depolarizaton-evoked changes of intracellular Ca2+ concentration in a rat pheochromocytoma cell line
    • Fontainhas, A. M., Obukhov, A. G., and Nowycky, M. C. (2005) Protein kinase Calpha modulates depolarizaton-evoked changes of intracellular Ca2+ concentration in a rat pheochromocytoma cell line. Neuroscience 133, 393-403
    • (2005) Neuroscience , vol.133 , pp. 393-403
    • Fontainhas, A.M.1    Obukhov, A.G.2    Nowycky, M.C.3
  • 37
    • 2142817395 scopus 로고
    • Stimulation of ribosomal protein S6 kinase activity by pp60v-src or by serum: Dissociation from phorbol ester-stimulated activity
    • Blenis, J., and Erikson, R. L. (1986) Stimulation of ribosomal protein S6 kinase activity by pp60v-src or by serum: dissociation from phorbol ester-stimulated activity. Proc. Natl. Acad. Sci. USA 83, 1733-1737
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 1733-1737
    • Blenis, J.1    Erikson, R.L.2
  • 38
    • 4544384577 scopus 로고    scopus 로고
    • Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase
    • Roux, P. P., Ballif, B. A., Anjum, R., Gygi, S. P., and Blenis, J. (2004) Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase. Proc. Natl. Acad. Sci. USA 101, 13489-13494
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 13489-13494
    • Roux, P.P.1    Ballif, B.A.2    Anjum, R.3    Gygi, S.P.4    Blenis, J.5
  • 39
    • 0141733228 scopus 로고    scopus 로고
    • Inactivation of the tuberous sclerosis complex-1 and -2 gene products occurs by phosphoinositide 3-kinase/Akt-dependent and -independent phosphorylation of tuberin
    • Tee, A. R., Anjum, R., and Blenis, J. (2003) Inactivation of the tuberous sclerosis complex-1 and -2 gene products occurs by phosphoinositide 3-kinase/Akt-dependent and -independent phosphorylation of tuberin. J. Biol. Chem. 278, 37288-37296
    • (2003) J. Biol. Chem. , vol.278 , pp. 37288-37296
    • Tee, A.R.1    Anjum, R.2    Blenis, J.3
  • 40
    • 0037192868 scopus 로고    scopus 로고
    • The extracellular signal-regulated kinase pathway regulates the phosphorylation of 4E-BP1 at multiple sites
    • Herbert, T. P., Tee, A. R., and Proud, C. G. (2002) The extracellular signal-regulated kinase pathway regulates the phosphorylation of 4E-BP1 at multiple sites. J. Biol. Chem. 277, 11591-11596
    • (2002) J. Biol. Chem. , vol.277 , pp. 11591-11596
    • Herbert, T.P.1    Tee, A.R.2    Proud, C.G.3
  • 41
    • 0028178928 scopus 로고
    • PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase
    • Chung, J., Grammer, T. C., Lemon, K. P., Kazlauskas, A., and Blenis, J. (1994) PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase. Nature (London) 370, 71-75
    • (1994) Nature (London) , vol.370 , pp. 71-75
    • Chung, J.1    Grammer, T.C.2    Lemon, K.P.3    Kazlauskas, A.4    Blenis, J.5
  • 42
    • 0028908804 scopus 로고
    • Activation of pp70/85 S6 kinases in interleukin-2-responsive lymphoid cells is mediated by phosphatidylinositol 3-kinase and inhibited by cyclic AMP
    • Monfar, M., Lemon, K. P., Grammer, T. C., Cheatham, L., Chung, J., Vlahos, C. J., and Blenis, J. (1995) Activation of pp70/85 S6 kinases in interleukin-2-responsive lymphoid cells is mediated by phosphatidylinositol 3-kinase and inhibited by cyclic AMP. Mol. Cell. Biol. 15, 326-337
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 326-337
    • Monfar, M.1    Lemon, K.P.2    Grammer, T.C.3    Cheatham, L.4    Chung, J.5    Vlahos, C.J.6    Blenis, J.7
  • 43
    • 0035012605 scopus 로고    scopus 로고
    • HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: Novel mechanism for HIF-1-mediated vascular endothelial growth factor expression
    • Laughner, E., Taghavi, P., Chiles, K., Mahon, P. C., and Semenza, G. L. (2001) HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression. Mol. Cell. Biol. 21, 3995-4004
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 3995-4004
    • Laughner, E.1    Taghavi, P.2    Chiles, K.3    Mahon, P.C.4    Semenza, G.L.5
  • 44
    • 0037073695 scopus 로고    scopus 로고
    • Induction of hypoxia-inducible factor-1alpha by transcriptional and translational mechanisms
    • Page, E. L., Robitaille, G. A., Pouyssegur, J., and Richard, D. E. (2002) Induction of hypoxia-inducible factor-1alpha by transcriptional and translational mechanisms. J. Biol. Chem. 277, 48403-48409
    • (2002) J. Biol. Chem. , vol.277 , pp. 48403-48409
    • Page, E.L.1    Robitaille, G.A.2    Pouyssegur, J.3    Richard, D.E.4
  • 46
    • 0028859483 scopus 로고
    • Hypoxia-induced protein binding to O2-responsive sequences on the tyrosine hydroxylase gene
    • Norris, M. L., and Millhorn, D. E. (1995) Hypoxia-induced protein binding to O2-responsive sequences on the tyrosine hydroxylase gene. J. Biol. Chem. 270, 23774-23779
    • (1995) J. Biol. Chem. , vol.270 , pp. 23774-23779
    • Norris, M.L.1    Millhorn, D.E.2
  • 48
    • 0035341268 scopus 로고    scopus 로고
    • How protein kinase C activation protects nerve cells from oxidative stress-induced cell death
    • Maher, P. (2001) How protein kinase C activation protects nerve cells from oxidative stress-induced cell death. J. Neurosci. 21, 2929-2938
    • (2001) J. Neurosci. , vol.21 , pp. 2929-2938
    • Maher, P.1
  • 49
    • 0038661168 scopus 로고    scopus 로고
    • Neuroprotection and neurorescue against Abeta toxicity and PKC-dependent release of nonamyloidogenic soluble precursor protein by green tea polyphenol (-)-epigallocatechin-3-gallate
    • Levites, Y., Amit, T., Mandel, S., and Youdim, M. B. H. (2003) Neuroprotection and neurorescue against Abeta toxicity and PKC-dependent release of nonamyloidogenic soluble precursor protein by green tea polyphenol (-)-epigallocatechin-3-gallate. FASEB J. 17, 952-954
    • (2003) FASEB J. , vol.17 , pp. 952-954
    • Levites, Y.1    Amit, T.2    Mandel, S.3    Youdim, M.B.H.4
  • 50
    • 6944242126 scopus 로고    scopus 로고
    • Neuroprotection via pro-survival protein kinase C isoforms associated with Bcl-2 family members
    • Weinreb, O., Bar-Am, O., Amit, T., Chillag-Talmor, O., and Youdim, M. B. H. (2004) Neuroprotection via pro-survival protein kinase C isoforms associated with Bcl-2 family members. FASEB J. 18, 1471-1473
    • (2004) FASEB J. , vol.18 , pp. 1471-1473
    • Weinreb, O.1    Bar-Am, O.2    Amit, T.3    Chillag-Talmor, O.4    Youdim, M.B.H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.