Reactive oxygen species in the plasticity of respiratory behavior elicited by chronic intermittent hypoxia

Journal of Applied Physiology

Volumn 94, Issue 6, 2003, Pages 2342-2349

  Peng, Ying Jie ^a   Prabhakar, Nanduri R ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Episodic hypoxia; Long term facilitation; Recurrent apnea; Respiratory motor output; Superoxide anions

Indexed keywords

CHLORIDE; MANGANESE; MANGANESE TETRAKIS(1 METHYL 4 PYRIDYL)PORPHYRIN PENTACHLORIDE; OXYGEN RADICAL; REACTIVE OXYGEN METABOLITE; SCAVENGER; SUPEROXIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APNEA; ARTICLE; ARTIFICIAL VENTILATION; BREATHING; CONTROLLED STUDY; HYPOXIA; MALE; NERVE CELL PLASTICITY; NERVE CONDUCTION; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PHRENIC NERVE; PRIORITY JOURNAL; RAT; RECURRENT DISEASE; RESPIRATORY NERVE CELL;

EID: 0037502896     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/japplphysiol.00613.2002     Document Type: Article

References (23)

1. Adhikary G, Kline DD, Yuan G, Kumar GK, Simonson MS, Cherniack NS, and Prabhakar NR. Gene regulation during intermittent hypoxia: evidence for the involvement of reactive oxygen species. Adv Exp Med Biol 499: 297-302, 2001.
2. Baker TL and Mitchell GS. Episodic but not continuous hypoxia elicits long-term facilitation of phrenic motor output in rats. J Physiol 529: 215-219, 2000.
3. Dyugovskaya L, Lavie P, and Lavie L. Increased adhesion molecules expression and production of reactive oxygen species in leukocytes of sleep apnea patients. Am J Respir Crit Care Med 165: 934-939, 2002.
4. Fregosi RF and Mitchell GS. Long-term facilitation of inspiratory intercostal nerve activity following carotid sinus nerve stimulation in cats. J Physiol 477: 469-479, 1994.
5. Fuller DD, Bach KB, Baker TL, Kinkead R, and Mitchell GS. Long term facilitation of phrenic motor output. Respir Physiol 121: 135-146, 2000.
6. Fuller DD, Baker TL, Behan M, and Mitchell GS. Expression of hypoglossal long-term facilitation differs between substrains of Sprague-Dawley rat. Physiol Genomics 4: 175-181, 2001.
7. Fuller DD, Zabka AG, Baker TL, and Mitchell GS. Phrenic long-term facilitation requires 5-HT receptor activation during but not following episodic hypoxia. J Appl Physiol 90: 2001-2006, 2001.
8. Hayashi F, Coles SK, Bach KB, Mitchell GS, and McCrimmon DR. Time-dependent phrenic nerve responses to carotid afferent activation: intact vs. decerebellate rats. Am J Physiol Regul Integr Comp Physiol 265: R811-R819, 1993.
9. Kline DD, Overholt JL, and Prabhakar NR. Mutant mice deficient in NOS-1 exhibit attenuated long-term facilitation and short-term potentiation in breathing. J Physiol 539: 309-315, 2002.
10. Ling L, Fuller DD, Bach KB, Kinkead R, Olson EB Jr, and Mitchell GS. Chronic intermittent hypoxia elicits serotonin-dependent plasticity in the central neural control of breathing. J Neurosci 21: 5381-5388, 2001.
11. Martin PA and Mitchell GS. Long-term modulation of the exercise ventilatory response in goats. J Physiol 470: 601-617, 1993.
12. Millhorn DE. Stimulation of raphe (obscurus) nucleus causes long-term potentiation of phrenic nerve activity in cat. J Physiol 381: 169-179, 1986.
13. Millhorn DE, Eldridge FL, and Waldrop TG. Prolonged stimulation of respiration by endogenous central serotonin. Respir Physiol 42: 171-188, 1980.
14. Millhorn DE, Eldridge FL, and Waldrop TG. Prolonged stimulation of respiration by a new central neural mechanism. Respir Physiol 41: 87-103, 1980.
15. Mitchell GS, Baker TL, Nanda SA, Fuller DD, Zabka AG, Hodgeman BA, Bavis RW, Mack KJ, and Olson EB Jr. Intermittent hypoxia and respiratory plasticity. J Appl Physiol 90: 2466-2475, 2001.
16. Olson EB Jr, Bohne CJ, Dwinell MR, Podolsky A, Vidruk EH, Fuller DD, Powell FL, and Mitchel GS. Ventilatory long-term facilitation in unanesthetized rats. J Appl Physiol 91: 709-716, 2001.
17. Peng Y, Kline DD, Hamedani A, and Prabhakar NR. Induction of long term facilitation in the carotid body activity by intermittent hypoxia (Abstract). FASEB J 15: A153, 2001.
18. Peng YJ, Kumar GK, Kline DD, and Prabhakar NR. Long-term facilitation (LTF) of carotid body sensory activity by episodic hypoxia: evidence for impaired mitochondrial respiration (Abstract). FASEB J 16: A827, 2002.
19. Powell FL, Milsom WK, and Mitchell GS. Time domains of the hypoxic ventilatory response. Respir Physiol 112: 123-134, 1998.
20. Prabhakar NR. Oxygen sensing during intermittent hypoxia: cellular and molecular mechanisms. J Appl Physiol 90: 1986-1994, 2001.
21. Prabhakar NR. Sleep apneas: an oxidative stress? Am J Respir Crit Care Med 165: 859-860, 2002.
22. Schulz R, Mahmoudi S, Hattar K, Sibelius U, Olschewski H, Mayer K, Seeger W, and Grimminger F. Enhanced release of superoxide from polymorphonuclear neutrophils in obstructive sleep apnea. Impact of continuous positive airway pressure therapy. Am J Respir Crit Care Med 162: 566-570, 2000.
23. Turner DL and Mitchell GS. Long-term facilitation of ventilation following repeated hypoxic episodes in awake goats. J Physiol 499: 543-550, 1997.