3-Amino-2(5H)furanones as inhibitors of subgenomic hepatitis C virus RNA replication

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 21, 2008, Pages 9610-9615

  Iannazzo, Daniela ^a   Piperno, Anna ^a   Romeo, Giovanni ^a   Romeo, Roberto ^a   Chiacchio, Ugo ^b   Rescifina, Antonio ^b   Balestrieri, Emanuela ^c   Macchi, Beatrice ^c   Mastino, Antonio ^a   Cortese, Riccardo ^d  

^a UNIVERSITY OF MESSINA   (Italy)

^b UNIVERSITY OF CATANIA   (Italy)

^c UNIVERSITY OF ROME TOR VERGATA   (Italy)

^d CEINGE BIOTECNOLOGIE AVANZATE   (Italy)

Author keywords

1,3 Dipolar cycloaddition; DKA; Furanones; HCV; Isoxazolidines

Indexed keywords

2,5 DIHYDRO 2 METHYL 4 (METHYLAMINO) 5 OXO N PHENYLFURAN 3 CARBOXAMIDE; 3 AMINO 2(5H) FURANONE DERIVATIVE; ALPHA INTERFERON; ISOXAZOLIDINE DERIVATIVE; OXOACID; UNCLASSIFIED DRUG; VIRUS RNA;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SYNTHESIS; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; NONHUMAN; REACTION ANALYSIS; RNA REPLICATION; STRUCTURE ACTIVITY RELATION; VIRUS GENOME;

ANTIVIRAL AGENTS; CARCINOMA, HEPATOCELLULAR; CELL PROLIFERATION; FURANS; GENOME, VIRAL; HEPACIVIRUS; HEPATITIS C; HUMANS; LIVER NEOPLASMS; MOLECULAR STRUCTURE; REPLICON; RNA, VIRAL; TUMOR CELLS, CULTURED; VIRAL NONSTRUCTURAL PROTEINS; VIRUS REPLICATION;

HEPATITIS C VIRUS;

EID: 53749105428     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.09.006     Document Type: Article

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