Targeting NS5B RNA-dependent RNA polymerase for anti-HCV chemotherapy

Current Drug Targets - Infectious Disorders

Volumn 3, Issue 3, 2003, Pages 207-219

  Wu, Jim Zhen ^a   Hong, Zhi ^a  

^a Ribapharm Inc   (United States)

Author keywords

Drug resistance; Genetic variability; HCV; Hepatitis C virus; Non nucleoside inhibitor; NS5B RNA dependent RNA polymerase; Nucleoside analogue

Indexed keywords

1,3 DIOXOLANE DERIVATIVE; ADENOSINE DERIVATIVE; ANTIVIRUS AGENT; BENZAMIDE DERIVATIVE; BENZIMIDAZOLE DERIVATIVE; BENZOTHIADIAZINE DERIVATIVE; BENZOTHIOPHENE DERIVATIVE; CYTIDINE DERIVATIVE; DEOXYRIBONUCLEOSIDE; DNA POLYMERASE; GEMCITABINE; HETEROCYCLIC COMPOUND; JTK 003; JTK 109; NAPHTHYRIDINE DERIVATIVE; OXOACID; PRODRUG; PYRIMIDINE DERIVATIVE; PYRIMIDIODIONE DERIVATIVE; PYRROLIDINE DERIVATIVE; RHODANINE; RIBAMIDINE; RIBAVIRIN; RIBONUCLEOSIDE DERIVATIVE; RNA DIRECTED RNA POLYMERASE; RNA DIRECTED RNA POLYMERASE INHIBITOR; RNA POLYMERASE; THIOSEMICARBAZONE DERIVATIVE; TRIAZINE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

CATALYSIS; CELLULAR DISTRIBUTION; CLINICAL TRIAL; CYTOPLASM; DRUG DESIGN; DRUG EFFICACY; DRUG INDUSTRY; DRUG SPECIFICITY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; DRUG TOLERABILITY; ENDOPLASMIC RETICULUM; ENZYME STRUCTURE; GENETIC VARIABILITY; HEPATITIS C; HUMAN; MEDICAL LITERATURE; PATENT; PREVALENCE; REVIEW; VIRUS REPLICATION;

AMINO ACID SEQUENCE; ANTIVIRAL AGENTS; CATALYSIS; DRUG DESIGN; GENOTYPE; HEPATITIS C; HUMANS; MOLECULAR SEQUENCE DATA; RNA REPLICASE; VIRAL NONSTRUCTURAL PROTEINS;

EID: 0141426816     PISSN: 15680053     EISSN: None     Source Type: Journal    
DOI: 10.2174/1568005033481114     Document Type: Review

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