-
1
-
-
33646134826
-
Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells
-
Banziger C, Soldini D, Schutt C, Zipperlen P, Hausmann G, Basler K (2006) Wntless, a conserved membrane protein dedicated to the secretion of Wnt proteins from signaling cells. Cell 125: 509-522
-
(2006)
Cell
, vol.125
, pp. 509-522
-
-
Banziger, C.1
Soldini, D.2
Schutt, C.3
Zipperlen, P.4
Hausmann, G.5
Basler, K.6
-
2
-
-
33646123992
-
Secretion of Wnt ligands requires Evi, a conserved transmembrane protein
-
Bartscherer K, Pelte N, Ingelfinger D, Boutros M (2006) Secretion of Wnt ligands requires Evi, a conserved transmembrane protein. Cell 125: 523-533
-
(2006)
Cell
, vol.125
, pp. 523-533
-
-
Bartscherer, K.1
Pelte, N.2
Ingelfinger, D.3
Boutros, M.4
-
3
-
-
37749040775
-
The retromer complex influences Wnt secretion by recycling wntless from endosomes to the trans-Golgi network
-
Belenkaya TY, Wu Y, Tang X, Zhou B, Cheng L, Sharma YV, Yan D, Selva EM, Lin X (2008) The retromer complex influences Wnt secretion by recycling wntless from endosomes to the trans-Golgi network. Dev Cell 14 120-131
-
(2008)
Dev Cell
, vol.14
, pp. 120-131
-
-
Belenkaya, T.Y.1
Wu, Y.2
Tang, X.3
Zhou, B.4
Cheng, L.5
Sharma, Y.V.6
Yan, D.7
Selva, E.M.8
Lin, X.9
-
4
-
-
0033598964
-
Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling cells
-
Burke R, Nellen D, Bellotto M, Hafen E, Senti KA, Dickson BJ, Basler K (1999) Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling cells. Cell 99: 803-815
-
(1999)
Cell
, vol.99
, pp. 803-815
-
-
Burke, R.1
Nellen, D.2
Bellotto, M.3
Hafen, E.4
Senti, K.A.5
Dickson, B.J.6
Basler, K.7
-
5
-
-
1842853184
-
Palmitoylation is required for the production of a soluble multimeric Hedgehog protein complex and longrange signaling in vertebrates
-
Chen MH, Li YJ, Kawakami T, Xu SM, Chuang PT (2004) Palmitoylation is required for the production of a soluble multimeric Hedgehog protein complex and longrange signaling in vertebrates. Genes Dev 18 641-659
-
(2004)
Genes Dev
, vol.18
, pp. 641-659
-
-
Chen, M.H.1
Li, Y.J.2
Kawakami, T.3
Xu, S.M.4
Chuang, P.T.5
-
6
-
-
47749112412
-
Lipid-independent secretion of a Drosophila Wnt protein
-
Ching W, Hang HC, Nusse R (2008) Lipid-independent secretion of a Drosophila Wnt protein. J Biol Chem 25: 17092-17098
-
(2008)
J Biol Chem
, vol.25
, pp. 17092-17098
-
-
Ching, W.1
Hang, H.C.2
Nusse, R.3
-
7
-
-
33746808398
-
Wnt/beta-catenin signaling in development and disease
-
Clevers H (2006) Wnt/beta-catenin signaling in development and disease. Cell 127: 469-480
-
(2006)
Cell
, vol.127
, pp. 469-480
-
-
Clevers, H.1
-
8
-
-
33646592268
-
Wnt gradient formation requires retromer function in Wnt-producing cells
-
Coudreuse DY, Roel G, Betist MC, Destree O, Korswagen HC (2006) Wnt gradient formation requires retromer function in Wnt-producing cells. Science 312: 921-924
-
(2006)
Science
, vol.312
, pp. 921-924
-
-
Coudreuse, D.Y.1
Roel, G.2
Betist, M.C.3
Destree, O.4
Korswagen, H.C.5
-
9
-
-
34250870665
-
Lipoprotein-heparan sulfate interactions in the Hh pathway
-
Eugster C, Panakova D, Mahmoud A, Eaton S (2007) Lipoprotein-heparan sulfate interactions in the Hh pathway. Dev Cell 13: 57-71
-
(2007)
Dev Cell
, vol.13
, pp. 57-71
-
-
Eugster, C.1
Panakova, D.2
Mahmoud, A.3
Eaton, S.4
-
10
-
-
38849106101
-
Wingless secretion requires endosome-to-Golgi retrieval of Wntless/Evi/Sprinter by the retromer complex
-
Franch-Marro X, Wendler F, Guidato S, Griffith J, Baena-Lopez A, Itasaki N, Maurice MM, Vincent JP (2008) Wingless secretion requires endosome-to-Golgi retrieval of Wntless/Evi/Sprinter by the retromer complex. Nat Cell Biol 10: 170-177
-
(2008)
Nat Cell Biol
, vol.10
, pp. 170-177
-
-
Franch-Marro, X.1
Wendler, F.2
Guidato, S.3
Griffith, J.4
Baena-Lopez, A.5
Itasaki, N.6
Maurice, M.M.7
Vincent, J.P.8
-
11
-
-
0037321854
-
Cholesterol modification of hedgehog is required for trafficking and movement, revealing an asymmetric cellular response to hedgehog
-
Gallet A, Rodriguez R, Ruel L, Therond PP (2003) Cholesterol modification of hedgehog is required for trafficking and movement, revealing an asymmetric cellular response to hedgehog. Dev Cell 4: 191-204
-
(2003)
Dev Cell
, vol.4
, pp. 191-204
-
-
Gallet, A.1
Rodriguez, R.2
Ruel, L.3
Therond, P.P.4
-
12
-
-
43049138477
-
Cellular trafficking of the glypican Dally-like is required for full-strength Hedgehog signaling and wingless transcytosis
-
Gallet AL, Staccini-Lavenant L, Therond PP (2008) Cellular trafficking of the glypican Dally-like is required for full-strength Hedgehog signaling and wingless transcytosis. Dev Cell 14: 712-725
-
(2008)
Dev Cell
, vol.14
, pp. 712-725
-
-
Gallet, A.L.1
Staccini-Lavenant, L.2
Therond, P.P.3
-
13
-
-
33846138014
-
Sprinter: A novel transmembrane protein required for Wg secretion and signaling
-
Goodman RM, Thombre S, Firtina Z, Gray D, Betts D, Roebuck J, Spana EP, Selva EM (2006) Sprinter: A novel transmembrane protein required for Wg secretion and signaling. Development 133: 4901-4911
-
(2006)
Development
, vol.133
, pp. 4901-4911
-
-
Goodman, R.M.1
Thombre, S.2
Firtina, Z.3
Gray, D.4
Betts, D.5
Roebuck, J.6
Spana, E.P.7
Selva, E.M.8
-
14
-
-
0035823004
-
Argosomes: A potential vehicle for the spread of morphogens through epithelia
-
Greco V, Hannus M, Eaton S (2001) Argosomes: A potential vehicle for the spread of morphogens through epithelia. Cell 106: 633-645
-
(2001)
Cell
, vol.106
, pp. 633-645
-
-
Greco, V.1
Hannus, M.2
Eaton, S.3
-
15
-
-
26244449664
-
loss- and gain-of-function analysis of the lipid raft proteins Reggie/Flotillin in Drosophila: They are posttranslationally regulated, and misexpression interferes with wing and eye development
-
Hoehne M, de couet HG, Stuermer CA, Fischbach KF (2005) loss- and gain-of-function analysis of the lipid raft proteins Reggie/Flotillin in Drosophila: They are posttranslationally regulated, and misexpression interferes with wing and eye development. Mol Cell Neurosci 30: 326-338
-
(2005)
Mol Cell Neurosci
, vol.30
, pp. 326-338
-
-
Hoehne, M.1
de couet, H.G.2
Stuermer, C.A.3
Fischbach, K.F.4
-
16
-
-
0030450052
-
The segment polarity gene porcupine encodes a putative multitransmembrane protein involved in Wingless processing
-
Kadowaki T, Wilder E, Klingensmith J, Zachary K, Perrimon N (1996) The segment polarity gene porcupine encodes a putative multitransmembrane protein involved in Wingless processing. Genes Dev 10: 3116-3128
-
(1996)
Genes Dev
, vol.10
, pp. 3116-3128
-
-
Kadowaki, T.1
Wilder, E.2
Klingensmith, J.3
Zachary, K.4
Perrimon, N.5
-
17
-
-
38949159320
-
Reggie-1/flotillin-2 promotes secretion of the longrange signalling forms of Wingless and Hedgehog in Drosophila
-
Katanaev VL, Solis GP, Hausmann G, Buestorf S, Katanayeva N, Schrock Y, Stuermer CA, Basler K (2008) Reggie-1/flotillin-2 promotes secretion of the longrange signalling forms of Wingless and Hedgehog in Drosophila. EMBO J 27: 509-521
-
(2008)
EMBO J
, vol.27
, pp. 509-521
-
-
Katanaev, V.L.1
Solis, G.P.2
Hausmann, G.3
Buestorf, S.4
Katanayeva, N.5
Schrock, Y.6
Stuermer, C.A.7
Basler, K.8
-
18
-
-
0036922902
-
Mouse dispatched mutants fail to distribute hedgehog proteins and are defective in hedgehog signaling
-
Kawakami T, Kawcak T, Li YJ, Zhang W, Hu Y, Chuang PT (2002) Mouse dispatched mutants fail to distribute hedgehog proteins and are defective in hedgehog signaling. Development 129: 5753-5765
-
(2002)
Development
, vol.129
, pp. 5753-5765
-
-
Kawakami, T.1
Kawcak, T.2
Li, Y.J.3
Zhang, W.4
Hu, Y.5
Chuang, P.T.6
-
19
-
-
42549164807
-
Wnt signalling and its impact on development and cancer
-
Klaus A, Birchmeier W (2008) Wnt signalling and its impact on development and cancer. Nat Rev Cancer 8: 387-398
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 387-398
-
-
Klaus, A.1
Birchmeier, W.2
-
20
-
-
0029810885
-
Molecular characterization and developmental expression of a retinoid- and fatty acid-binding glycoprotein from Drosophila. A putative lipophorin
-
Kutty RK, Kutty G, Kambadur R, Duncan T, Koonin EV, Rodriguez IR, Odenwald WF, Wiggert B (1996) Molecular characterization and developmental expression of a retinoid- and fatty acid-binding glycoprotein from Drosophila. A putative lipophorin. J Biol Chem 271: 20641-20649
-
(1996)
J Biol Chem
, vol.271
, pp. 20641-20649
-
-
Kutty, R.K.1
Kutty, G.2
Kambadur, R.3
Duncan, T.4
Koonin, E.V.5
Rodriguez, I.R.6
Odenwald, W.F.7
Wiggert, B.8
-
21
-
-
31744439979
-
Palmitoylation of the EGFR ligand Spitz by Rasp increases Spitz activity by restricting its diffusion
-
Miura GI, Buglino J, Alvarado D, Lemmon MA, Resh MD, Treisman JE (2006) Palmitoylation of the EGFR ligand Spitz by Rasp increases Spitz activity by restricting its diffusion. Dev Cell 10: 167-176
-
(2006)
Dev Cell
, vol.10
, pp. 167-176
-
-
Miura, G.I.1
Buglino, J.2
Alvarado, D.3
Lemmon, M.A.4
Resh, M.D.5
Treisman, J.E.6
-
22
-
-
37749052695
-
-
Pan CL, Baum PD, Gu M, Jorgensen EM, Clark SG, Garriga G (2008) C. elegans ap2 and retromer control Wnt signaling by regulating mig-14/Wntless. Dev Cell 14: 132-139
-
Pan CL, Baum PD, Gu M, Jorgensen EM, Clark SG, Garriga G (2008) C. elegans ap2 and retromer control Wnt signaling by regulating mig-14/Wntless. Dev Cell 14: 132-139
-
-
-
-
23
-
-
18344378499
-
Lipoprotein particles are required for Hedgehog and Wingless signalling
-
Panakova D, Sprong H, Marois E, Thiele C, Eaton S (2005) Lipoprotein particles are required for Hedgehog and Wingless signalling. Nature 435: 58-65
-
(2005)
Nature
, vol.435
, pp. 58-65
-
-
Panakova, D.1
Sprong, H.2
Marois, E.3
Thiele, C.4
Eaton, S.5
-
24
-
-
15444359695
-
Identification of a palmitic acid-modified form of human Sonic hedgehog
-
Pepinsky RB et al (1998) Identification of a palmitic acid-modified form of human Sonic hedgehog. J Biol Chem 273: 14037-14045
-
(1998)
J Biol Chem
, vol.273
, pp. 14037-14045
-
-
Pepinsky, R.B.1
-
25
-
-
0037018854
-
Producing cells retain and recycle Wingless in Drosophila embryos
-
Pfeiffer S, Ricardo S, Manneville JB, Alexandre C, Vincent JP (2002) Producing cells retain and recycle Wingless in Drosophila embryos. Curr Biol 12: 957-962
-
(2002)
Curr Biol
, vol.12
, pp. 957-962
-
-
Pfeiffer, S.1
Ricardo, S.2
Manneville, J.B.3
Alexandre, C.4
Vincent, J.P.5
-
26
-
-
31144448719
-
Arrow (LRP6) and Frizzled2 cooperate to degrade Wingless in Drosophila imaginal discs
-
Piddini E, Marshall F, Dubois L, Hirst E, Vincent JP (2005) Arrow (LRP6) and Frizzled2 cooperate to degrade Wingless in Drosophila imaginal discs. Development 132: 5479-5489
-
(2005)
Development
, vol.132
, pp. 5479-5489
-
-
Piddini, E.1
Marshall, F.2
Dubois, L.3
Hirst, E.4
Vincent, J.P.5
-
27
-
-
38849134055
-
Wingless secretion promotes and requires retromer-dependent cycling of Wntless
-
Port F, Kuster M, Herr P, Furger E, Banziger C, Hausmann G, Basler K (2008) Wingless secretion promotes and requires retromer-dependent cycling of Wntless. Nat Cell Biol 10: 178-185
-
(2008)
Nat Cell Biol
, vol.10
, pp. 178-185
-
-
Port, F.1
Kuster, M.2
Herr, P.3
Furger, E.4
Banziger, C.5
Hausmann, G.6
Basler, K.7
-
28
-
-
0029844192
-
Cholesterol modification of hedgehog signaling proteins in animal development
-
Porter JA, Young KE, Beachy PA (1996) Cholesterol modification of hedgehog signaling proteins in animal development. Science 274 255-259
-
(1996)
Science
, vol.274
, pp. 255-259
-
-
Porter, J.A.1
Young, K.E.2
Beachy, P.A.3
-
29
-
-
33744507945
-
Wnt signaling establishes anteroposterior polarity and requires retromer in C. elegans
-
Prasad BC, Clark SG (2006) Wnt signaling establishes anteroposterior polarity and requires retromer in C. elegans. Development 133 1757-1766
-
(2006)
Development
, vol.133
, pp. 1757-1766
-
-
Prasad, B.C.1
Clark, S.G.2
-
30
-
-
0033597141
-
Association of sterol-and glycosylphosphatidylinositol-linked proteins with Drosophila raft lipid microdomains
-
Rietveld A, Neutz S, Simons K, Eaton S (1999) Association of sterol-and glycosylphosphatidylinositol-linked proteins with Drosophila raft lipid microdomains. J Biol Chem 274: 12049-12054
-
(1999)
J Biol Chem
, vol.274
, pp. 12049-12054
-
-
Rietveld, A.1
Neutz, S.2
Simons, K.3
Eaton, S.4
-
31
-
-
23944448331
-
Lipoprotein-mediated lipid transport in insects: Analogy to the mammalian lipid carrier system and novel concepts for the functioning of LDL receptor family members
-
Rodenburg KW, Van der Horst DJ (2005) Lipoprotein-mediated lipid transport in insects: Analogy to the mammalian lipid carrier system and novel concepts for the functioning of LDL receptor family members. Biochim Biophys Acta 1736: 10-29
-
(2005)
Biochim Biophys Acta
, vol.1736
, pp. 10-29
-
-
Rodenburg, K.W.1
Van der Horst, D.J.2
-
32
-
-
13244275069
-
Recycle your receptors with retromer
-
Seaman MN (2005) Recycle your receptors with retromer. Trends Cell Biol 15: 68-75
-
(2005)
Trends Cell Biol
, vol.15
, pp. 68-75
-
-
Seaman, M.N.1
-
33
-
-
0034704824
-
Wingless gradient formation in the Drosophila wing
-
Strigini M, Cohen SM (2000) Wingless gradient formation in the Drosophila wing. Curr Biol 10: 293-300
-
(2000)
Curr Biol
, vol.10
, pp. 293-300
-
-
Strigini, M.1
Cohen, S.M.2
-
34
-
-
33751318469
-
Monounsaturated fatty acid modification of Wnt protein: Its role in Wnt secretion
-
Takada R, Satomi Y, Kurata Y, Ueno N, Norioka S, Kondoh H, Takao T, Takada S (2006) Monounsaturated fatty acid modification of Wnt protein: its role in Wnt secretion. Dev Cell 11: 791-801
-
(2006)
Dev Cell
, vol.11
, pp. 791-801
-
-
Takada, R.1
Satomi, Y.2
Kurata, Y.3
Ueno, N.4
Norioka, S.5
Kondoh, H.6
Takao, T.7
Takada, S.8
-
35
-
-
0027368963
-
Mutations in the segment polarity genes wingless and porcupine impair secretion of the wingless protein
-
van den Heuvel M, Harryman-Samos C, Klingensmith J, Perrimon N, Nusse R (1993) Mutations in the segment polarity genes wingless and porcupine impair secretion of the wingless protein. EMBO J 12: 5293-5302
-
(1993)
EMBO J
, vol.12
, pp. 5293-5302
-
-
van den Heuvel, M.1
Harryman-Samos, C.2
Klingensmith, J.3
Perrimon, N.4
Nusse, R.5
-
36
-
-
0037737726
-
Wnt proteins are lipid-modified and can act as stem cell growth factors
-
Willert K, Brown JD, Danenberg E, Duncan AW, Weissman IL, Reya T, Yates JR, Nusse R (2003) Wnt proteins are lipid-modified and can act as stem cell growth factors. Nature 423: 448-452
-
(2003)
Nature
, vol.423
, pp. 448-452
-
-
Willert, K.1
Brown, J.D.2
Danenberg, E.3
Duncan, A.W.4
Weissman, I.L.5
Reya, T.6
Yates, J.R.7
Nusse, R.8
-
37
-
-
37749043874
-
Wnt signaling requires retromer-dependent recycling of MIG-14/ Wntless in Wnt-producing cells
-
Yang PT, Lorenowicz MJ, Silhankova M, Coudreuse DY, Betist MC, Korswagen HC (2008) Wnt signaling requires retromer-dependent recycling of MIG-14/ Wntless in Wnt-producing cells. Dev Cell 14: 140-147
-
(2008)
Dev Cell
, vol.14
, pp. 140-147
-
-
Yang, P.T.1
Lorenowicz, M.J.2
Silhankova, M.3
Coudreuse, D.Y.4
Betist, M.C.5
Korswagen, H.C.6
-
38
-
-
0030606264
-
Direct and long-range action of a wingless morphogen gradient
-
Zecca M, Basler K, Struhl G (1996) Direct and long-range action of a wingless morphogen gradient. Cell 87: 833-844
-
(1996)
Cell
, vol.87
, pp. 833-844
-
-
Zecca, M.1
Basler, K.2
Struhl, G.3
-
39
-
-
0035822098
-
A freely diffusible form of Sonic hedgehog mediates long-range signalling
-
Zeng X, Goetz JA, Suber IM, Scott WJ, Schreiner CM, Robbins DJ (2001) A freely diffusible form of Sonic hedgehog mediates long-range signalling. Nature 411: 716-720
-
(2001)
Nature
, vol.411
, pp. 716-720
-
-
Zeng, X.1
Goetz, J.A.2
Suber, I.M.3
Scott, W.J.4
Schreiner, C.M.5
Robbins, D.J.6
-
40
-
-
4043154959
-
Drosophila wnt-1 undergoes a hydrophobic modification and is targeted to lipid rafts, a process that requires porcupine
-
Zhai L, Chaturvedi D, Cumberledge S (2004) Drosophila wnt-1 undergoes a hydrophobic modification and is targeted to lipid rafts, a process that requires porcupine. J Biol Chem 279: 33220-33227
-
(2004)
J Biol Chem
, vol.279
, pp. 33220-33227
-
-
Zhai, L.1
Chaturvedi, D.2
Cumberledge, S.3
|