Impact of retinal disease-associated RPE65 mutations on retinoid isomerization

Biochemistry

Volumn 47, Issue 37, 2008, Pages 9856-9865

  Bereta, Grzegorz ^a   Kiser, Philip D ^a   Golczak, Marcin ^a   Sun, Wenyu ^a   Heon, Elise ^b,c   Saperstein, David A ^c   Palczewski, Krzysztof ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACIDS; AMINATION; AMINES; AMINO ACIDS; ELECTRON TRANSITIONS; HEALTH; ISOMERS; NUCLEIC ACIDS; ORGANIC ACIDS; PROGRAMMING THEORY; STRUCTURAL ANALYSIS;

BICISTRONIC; BIOCHEMICAL STUDIES; CATALYTIC CENTERS; CELL SORTING; CODING REGIONS; CULTURED CELLS; DIRECT SEQUENCING; ENHANCED GREEN FLUORESCENT PROTEIN; ENZYMATIC ASSAYS; HOMOLOGY MODELING; IMMUNOBLOTTING; ISOMERASE ACTIVITY; OXYGENASE; PROMOTER REGION; RETINAL DISEASES; RETINITIS PIGMENTOSA; RETINOID; STRUCTURAL REQUIREMENTS; SYNECHOCYSTIS;

ISOMERIZATION;

CAROTENOID; ENHANCED GREEN FLUORESCENT PROTEIN; GLYCINE; ISOMERASE; OXYGENASE; RETINOID; VALINE;

AMINO ACID ANALYSIS; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; AUTOSOMAL DOMINANT INHERITANCE; AUTOSOMAL RECESSIVE INHERITANCE; CATALYSIS; CELL SELECTION; DNA SEQUENCE; DNA TEMPLATE; EMBRYO; ENZYME ACTIVITY; ENZYME ASSAY; EXON; GENE CONSTRUCT; GENE EXPRESSION; GENE FUNCTION; GENE INACTIVATION; GENE LOCATION; GENE MUTATION; GENE STRUCTURE; GENETIC MODEL; GENETIC STABILITY; GENETIC VARIABILITY; HUMAN; HUMAN CELL CULTURE; HUMAN GENOME; IMMUNOBLOTTING; INTRON; ISOMERIZATION; LEBER CONGENITAL AMAUROSIS; MAJOR CLINICAL STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RECESSIVE INHERITANCE; RETINA CONE; RETINA DYSTROPHY; RETINA ROD; RETINAL PIGMENTED EPITHELIUM 65 GENE; RETINITIS PIGMENTOSA; SEQUENCE HOMOLOGY; SYNECHOCYSTIS;

ANIMALS; CARRIER PROTEINS; CELLS, CULTURED; EXONS; EYE PROTEINS; GREEN FLUORESCENT PROTEINS; MICE; MODELS, MOLECULAR; MUTATION; NIH 3T3 CELLS; OXYGENASES; PROMOTER REGIONS (GENETICS); RETINAL DISEASES; RETINITIS PIGMENTOSA; RETINOIDS;

SYNECHOCYSTIS;

EID: 51849140512     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi800905v     Document Type: Article

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