The structure of a retinal-forming carotenoid oxygenase

Science

Volumn 308, Issue 5719, 2005, Pages 267-269

  Kloer, Daniel P ^a   Ruch, Sandra ^a   Al Babili, Salim ^a   Beyer, Peter ^a   Schulz, Georg E ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL BONDS; CONFORMATIONS; CRYSTAL STRUCTURE; DERIVATIVES; ENZYMES; EYE MOVEMENTS; OXYGEN; X RAY DIFFRACTION;

BOND CLEVAGE; CAROTENOID; NONPOLAR TUNNELS; RETINA;

VISION;

APOCAROTENOID 15,15' DIOXYGENASE; CAROTENOID; DETERGENT; FERROUS ION; HISTIDINE; IONONE DERIVATIVE; ISOPRENOID; OCTYLPOLYOXYETHYLENE; OXYGEN; OXYGENASE; RETINAL; UNCLASSIFIED DRUG; RECOMBINANT PROTEIN;

BIOCHEMISTRY;

ARTICLE; CHEMICAL BOND; CONFORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ELECTRON; ENZYME ACTIVE SITE; ENZYME STRUCTURE; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; SYNECHOCYSTIS; X RAY DIFFRACTION; AMINO ACID SEQUENCE; CHEMISTRY; ENZYMOLOGY; GENETICS; HUMAN; MOLECULAR CLONING; MOLECULAR GENETICS; PROTEIN CONFORMATION; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; CLONING, MOLECULAR; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; HUMANS; MOLECULAR SEQUENCE DATA; OXYGENASES; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; RETINALDEHYDE; SYNECHOCYSTIS;

EID: 16444383613     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1108965     Document Type: Article

References (34)

1. B. Camara, F. Bouvier, Arch. Biochem. Biophys. 430, 16 (2004).
2. G. Giuliano, S. Al-Babili, J. von Lintig, Trends Plant Sci. 8, 145 (2003).
3. D. DellaPenna, Science 285, 37S (1999).
4. S. H. Schwartz, B. C. Tan, D. A. Gage, J. A. D. Zeevaart, D. R. McCarty, Science 276, 1872 (1997).
5. J. von Lintig, K. Vogt, J. Biol. Chem. 275, 1191S (2000).
6. A. Wyss et al., Biochem. Biophys. Res. Commun. 271, 334 (2000).
7. T. M. Redmond et al., J. Biol. Chem. 276, 6560 (2001).
8. C. Kiefer et al., J. Biol. Chem. 276, 14110 (2001).
9. A. B. Barua, J. A. Olson, J. Nutrit. 130, 1996 (2000).
10. J. Bastien, C. Rochette-Egly, Gene 328, 1 (2004).
11. N. L. Mata et al., J. Biol. Chem. 279, 635 (2004).
12. S. M. Gu et al., Nat. Genet. 17, 194 (1997).
13. B. C. Tan et al., Plant J. 35, 44 (2003).
14. S. Iuchi et al., Plant J. 27, 325 (2001).
15. S. H. Schwartz, X. Qin, J. A. D. Zeevaart, J. Biol. Chem. 276, 25208 (2001).
16. J. Booker et al., Curr. Biol. 14, 1232 (2004).
17. S. H. Schwartz, X. Qin, M. C. Loewen, J. Biol. Chem. 279, 46940 (2004).
18. F. Bouvier, O. Dogbo, B. Camara, Science 300, 2089 (2033).
19. F. Bouvier, C. Suire, J. Mutterer, B. Camara, Plant Cell 15, 47 (2003).
20. K. H. Jung, V. D. Trivedi, J. L. Spudich, Mol. Microbiol. 47, 1513 (2003).
21. S. Ruch, P. Beyer, H. Ernst, S. Al-Babili, Mol. Microbiol. 55, 1015 (2005).
22. Materials and methods are available as supporting material on Science Online.
23. W.-D. Woggon, Pure Appl. Chem. 74, 1397 (2002).
24. S. A. Gillmor, A. Villasenor, R. Fletterick, E. Sigal, M. F. Browner, Nat. Struct. Biol. 4, 1003 (1997).
25. C. R. Lancaster, H. Michel, J. Mol. Biol. 286, 883 (1999).
26. G. Katona, U. Andréasson, E. M. Landau, L.-E. Andréasson, R. Neutze, J. Mol. Biol. 331, 681 (2003).
27. K. N. Ferreira, T. M. Iverson, K. Maghlaoui, J. Barber, S. Iwata, Science 303, 1831 (2004).
28. J. N. Varghese, W. G. Laver, P. M. Colman, Nature 303, 35 (1983).
29. T. Kajander et al., Structure 10, 483 (2002).
30. L. Holm, C. Sander, J. Mol. Biol. 233, 123 (1993).
31. E. I. Scharff, J. Koepke, G. Fritzsch, C. Lücke, H. Rüterjans, Structure 9, 493 (2001).
32. K. U. Wendt, A. Lenhart, G. E. Schulz, J. Mol, Biol. 286, 175 (1999).
33. P. Molnar, T. Körtvelyesi, Z. Matus, J. Szabolcs, J. Chem. Res. S, 120 (1997).
34. The atomic coordinates and structure factors are deposited in the Protein Data Bank under codes 2BIW and 2BIX. We thank A. Espin for technical assistance, the team of the Swiss Light Source for help in data collection, and the Deutsche Forschungsgemeinschaft (SFB-388), HarvestPlus, and the Badische Anilin und Soda Fabrik (BASF AG) for support.