A study on the fundamental factors determining the efficacy of siRNAs with high C/G contents

Cellular and Molecular Biology Letters

Volumn 13, Issue 2, 2008, Pages 283-302

  Liao, Jie Ying ^a   Yin, James Q ^a   Chen, Fang ^a   Liu, Tie Gang ^b   Yue, Jia Chang ^a  

^a INSTITUTE OF BIOPHYSICS   (China)

^b TUFTS MEDICAL CENTER   (United States)

Author keywords

Gene silencing; Local structure; mRNA; RNAi; siRNA

Indexed keywords

CALPAIN; CELL CYCLE PROTEIN 6; EPIDERMAL GROWTH FACTOR RECEPTOR 2; MESSENGER RNA; NUCLEOTIDE; OTOFERLIN; PROTEIN DERIVATIVE; SMALL INTERFERING RNA; TELOMERIC REPEAT BINDING FACTOR 2; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ARTICLE; EEF1D GENE; GENE; GENE MUTATION; GENE SILENCING; HUMAN; HUMAN CELL; RNA INTERFERENCE; RNA SEQUENCE; RNA STRUCTURE; BIOLOGICAL MODEL; CHEMISTRY; CONFORMATION; DNA BASE COMPOSITION; DOSE RESPONSE; DRUG EFFECT; GENETICS; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; TUMOR CELL LINE;

BASE COMPOSITION; BASE SEQUENCE; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE SILENCING; HUMANS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; RNA, MESSENGER; RNA, SMALL INTERFERING;

EID: 51549112629     PISSN: 14258153     EISSN: 16891392     Source Type: Journal    
DOI: 10.2478/s11658-008-0001-1     Document Type: Article

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