The NS3 protein of hepatitis C virus induces caspase-8-mediated apoptosis independent of its protease or helicase activities

Virology

Volumn 329, Issue 1, 2004, Pages 53-67

  Prikhod'Ko, Elena A ^a   Prikhod'Ko, Grigori G ^b   Siegel, Richard M ^a   Thompson, Peter ^c   Major, Marian E ^c   Cohen, Jeffrey I ^a  

^a Natl Inst Allerg Infect Dis N   (United States)

^b AMERICAN RED CROSS   (United States)

^c Ctr for Biologics Eval and Res   (United States)

Author keywords

Apoptosis; Caspase 8; Flavivirus; Hepatitis C virus

Indexed keywords

CASPASE 8; CASPASE 8 INHIBITOR; CASPASE 9; CASPASE INHIBITOR; FAS ANTIGEN; FAS ASSOCIATED DEATH DOMAIN PROTEIN; HELICASE; NONSTRUCTURAL PROTEIN 3; PROTEIN PRECURSOR; PROTEINASE; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL LINE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME INHIBITION; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; MAMMAL CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE; STRUCTURE ANALYSIS;

ANIMALS; APOPTOSIS; CASPASE 8; CASPASES; CELL LINE; CERCOPITHECUS AETHIOPS; DNA HELICASES; ENZYME ACTIVATION; HEPACIVIRUS; HUMANS; MOLECULAR SEQUENCE DATA; PEPTIDE HYDROLASES; RNA HELICASES; SEQUENCE ANALYSIS, DNA; VERO CELLS; VIRAL NONSTRUCTURAL PROTEINS;

ANIMALIA; FLAVIVIRUS; HEPATITIS C VIRUS; MAMMALIA; RNA VIRUSES;

EID: 5144227738     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.virol.2004.08.012     Document Type: Article

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