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Volumn 52, Issue 1, 2008, Pages 1-18

Mechanosensitive channels: Insights from continuum-based simulations

Author keywords

Continuum mechanics; Mechanobiology; Mechanosensitive channel; Simulation

Indexed keywords

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 51349132613     PISSN: 10859195     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12013-008-9024-5     Document Type: Review
Times cited : (15)

References (100)
  • 1
    • 0035069134 scopus 로고    scopus 로고
    • Molecular basis of mechanotransduction in living cells
    • OP Hamill B Martinac 2001 Molecular basis of mechanotransduction in living cells Physiological Reviews 81 685 740
    • (2001) Physiological Reviews , vol.81 , pp. 685-740
    • Hamill, O.P.1    Martinac, B.2
  • 2
    • 33744488545 scopus 로고    scopus 로고
    • Cellular mechanotransduction: Putting all the pieces together again
    • DE Ingber 2006 Cellular mechanotransduction: Putting all the pieces together again FASEB Journal 20 811 827
    • (2006) FASEB Journal , vol.20 , pp. 811-827
    • Ingber, D.E.1
  • 4
    • 3042853029 scopus 로고    scopus 로고
    • Mechanosensitive ion channels: Molecules of mechanotransduction
    • B Martinac 2004 Mechanosensitive ion channels: Molecules of mechanotransduction Journal of Cell Science 117 2449 2460
    • (2004) Journal of Cell Science , vol.117 , pp. 2449-2460
    • Martinac, B.1
  • 6
    • 33746828240 scopus 로고    scopus 로고
    • A finite element framework for studying the mechanical response of macromolecules: Application to the gating of the mechanosensitive channel MscL
    • Y Tang G Cao X Chen J Yoo A Yethiraj Q Cui 2006 A finite element framework for studying the mechanical response of macromolecules: Application to the gating of the mechanosensitive channel MscL Biophysical Journal 91 1248 1263
    • (2006) Biophysical Journal , vol.91 , pp. 1248-1263
    • Tang, Y.1    Cao, G.2    Chen, X.3    Yoo, J.4    Yethiraj, A.5    Cui, Q.6
  • 7
    • 47749143970 scopus 로고    scopus 로고
    • Gating mechanisms of the mechanosensitive channels of large conductance, Part I: Theoretical and numerical framework
    • X Chen Q Cui J Yoo Y Tang A Yethiraj 2008 Gating mechanisms of the mechanosensitive channels of large conductance, Part I: Theoretical and numerical framework Biophysical Journal 95 563 580
    • (2008) Biophysical Journal , vol.95 , pp. 563-580
    • Chen, X.1    Cui, Q.2    Yoo, J.3    Tang, Y.4    Yethiraj, A.5
  • 8
    • 47749128439 scopus 로고    scopus 로고
    • Gating mechanisms of mechanosensitive channels of large conductance part II: Systematic study of conformational transitions
    • Y Tang J Yoo A Yethiraj Q Cui X Chen 2008 Gating mechanisms of mechanosensitive channels of large conductance part II: Systematic study of conformational transitions Biophysical Journal 95 581 596
    • (2008) Biophysical Journal , vol.95 , pp. 581-596
    • Tang, Y.1    Yoo, J.2    Yethiraj, A.3    Cui, Q.4    Chen, X.5
  • 9
    • 0024277933 scopus 로고
    • A mechanosensitive ion channel in the yeast plasma-membrane
    • MC Gustin XL Zhou B Martinac C Kung 1988 A mechanosensitive ion channel in the yeast plasma-membrane Science 242 762 765
    • (1988) Science , vol.242 , pp. 762-765
    • Gustin, M.C.1    Zhou, X.L.2    Martinac, B.3    Kung, C.4
  • 10
  • 12
    • 0032545321 scopus 로고    scopus 로고
    • Structure of the MscL homolog from Mycobacterium tuberculosis: A gated mechanosensitive ion channel
    • G Chang RH Spencer AT Lee MT Barclay DC Rees 1998 Structure of the MscL homolog from Mycobacterium tuberculosis: A gated mechanosensitive ion channel Science 282 2220 2226
    • (1998) Science , vol.282 , pp. 2220-2226
    • Chang, G.1    Spencer, R.H.2    Lee, A.T.3    Barclay, M.T.4    Rees, D.C.5
  • 13
    • 0035825634 scopus 로고    scopus 로고
    • The gating mechanism of the large mechanosensitive channel MscL
    • S Sukharev M Betanzos CS Chiang HR Guy 2001 The gating mechanism of the large mechanosensitive channel MscL Nature 409 720 724
    • (2001) Nature , vol.409 , pp. 720-724
    • Sukharev, S.1    Betanzos, M.2    Chiang, C.S.3    Guy, H.R.4
  • 14
    • 2542496903 scopus 로고    scopus 로고
    • Mechanosensitive channels: What can we learn from 'simple' model systems?
    • S Sukharev A Anishkin 2004 Mechanosensitive channels: What can we learn from 'simple' model systems? Trends in Neurosciences 27 345 351
    • (2004) Trends in Neurosciences , vol.27 , pp. 345-351
    • Sukharev, S.1    Anishkin, A.2
  • 16
    • 0032935824 scopus 로고    scopus 로고
    • Energetic and spatial parameters for gating of the bacterial large conductance mechanosensitive channel, MscL
    • SI Sukharev WJ Sigurdson C Kung F Sachs 1999 Energetic and spatial parameters for gating of the bacterial large conductance mechanosensitive channel, MscL Journal of General Physiology 113 525 539
    • (1999) Journal of General Physiology , vol.113 , pp. 525-539
    • Sukharev, S.I.1    Sigurdson, W.J.2    Kung, C.3    Sachs, F.4
  • 17
    • 0028224356 scopus 로고
    • A large-conductance mechanosensitive channel in E. coli encoded by Mscl alone
    • SI Sukharev P Blount B Martinac FR Blattner C Kung 1994 A large-conductance mechanosensitive channel in E. coli encoded by Mscl alone Nature 368 265 268
    • (1994) Nature , vol.368 , pp. 265-268
    • Sukharev, S.I.1    Blount, P.2    Martinac, B.3    Blattner, F.R.4    Kung, C.5
  • 19
    • 0035756772 scopus 로고    scopus 로고
    • Mechanosensitive channel of Thermoplasma, the cell wall-less Archaea-cloning and molecular characterization
    • A Kloda B Martinac 2001 Mechanosensitive channel of Thermoplasma, the cell wall-less Archaea-cloning and molecular characterization Cell Biochemistry and Biophysics 34 321 347
    • (2001) Cell Biochemistry and Biophysics , vol.34 , pp. 321-347
    • Kloda, A.1    Martinac, B.2
  • 20
    • 0036725152 scopus 로고    scopus 로고
    • Physical principles underlying the transduction of bilayer deformation forces during mechanosensitive channel gating
    • E Perozo A Kloda DM Cortes B Martinac 2002 Physical principles underlying the transduction of bilayer deformation forces during mechanosensitive channel gating Nature Structural Biology 9 696 703
    • (2002) Nature Structural Biology , vol.9 , pp. 696-703
    • Perozo, E.1    Kloda, A.2    Cortes, D.M.3    Martinac, B.4
  • 21
    • 24644491716 scopus 로고    scopus 로고
    • Assessment of potential stimuli for mechano-dependent gating of MscL: Effects of pressure, tension and lipid headgroups
    • P Moe P Blount 2005 Assessment of potential stimuli for mechano-dependent gating of MscL: Effects of pressure, tension and lipid headgroups Biochemistry 44 12239 12244
    • (2005) Biochemistry , vol.44 , pp. 12239-12244
    • Moe, P.1    Blount, P.2
  • 22
    • 2942675244 scopus 로고    scopus 로고
    • Lipid bilayer pressure profiles and mechanosensitive channel gating
    • J Gullingsrud K Schulten 2004 Lipid bilayer pressure profiles and mechanosensitive channel gating Biophysical Journal 86 3496 3509
    • (2004) Biophysical Journal , vol.86 , pp. 3496-3509
    • Gullingsrud, J.1    Schulten, K.2
  • 23
    • 0041320859 scopus 로고    scopus 로고
    • Investigating lipid composition effects on the mechanosensitive channel of large conductance (MscL) using molecular dynamics simulations
    • DE Elmore DA Dougherty 2003 Investigating lipid composition effects on the mechanosensitive channel of large conductance (MscL) using molecular dynamics simulations Biophysical Journal 85 1512 1524
    • (2003) Biophysical Journal , vol.85 , pp. 1512-1524
    • Elmore, D.E.1    Dougherty, D.A.2
  • 26
    • 19644374616 scopus 로고    scopus 로고
    • Gating-by-tilt of mechanically sensitive membrane channels
    • MS Turner P Sens 2004 Gating-by-tilt of mechanically sensitive membrane channels Physical Review Letters 93 118103
    • (2004) Physical Review Letters , vol.93 , pp. 118103
    • Turner, M.S.1    Sens, P.2
  • 27
    • 0034271962 scopus 로고    scopus 로고
    • Spatial and energetic-entropic decomposition of surface tension in lipid bilayers from molecular dynamics simulations
    • E Lindahl O Edholm 2000 Spatial and energetic-entropic decomposition of surface tension in lipid bilayers from molecular dynamics simulations Journal of Chemical Physics 113 3882 3893
    • (2000) Journal of Chemical Physics , vol.113 , pp. 3882-3893
    • Lindahl, E.1    Edholm, O.2
  • 28
    • 33244458728 scopus 로고    scopus 로고
    • Gating prokaryotic mechanosensitive channels
    • E Perozo 2006 Gating prokaryotic mechanosensitive channels Nature Reviews Molecular Cell Biology 7 109 119
    • (2006) Nature Reviews Molecular Cell Biology , vol.7 , pp. 109-119
    • Perozo, E.1
  • 29
    • 23644451510 scopus 로고    scopus 로고
    • A possible unifying principle for mechanosensation
    • C Kung 2005 A possible unifying principle for mechanosensation Nature 436 647 654
    • (2005) Nature , vol.436 , pp. 647-654
    • Kung, C.1
  • 30
    • 33748566042 scopus 로고    scopus 로고
    • Thermodynamics of mechanosensitivity: Lipid shape, membrane deformation and anesthesia
    • VS Markin F Sachs 2004 Thermodynamics of mechanosensitivity: Lipid shape, membrane deformation and anesthesia Biophysical Journal 86 370A 370A
    • (2004) Biophysical Journal , vol.86
    • Markin, V.S.1    Sachs, F.2
  • 31
    • 21244464270 scopus 로고    scopus 로고
    • Membrane-protein interactions in mechanosensitive channels
    • P Wiggins R Philips 2005 Membrane-protein interactions in mechanosensitive channels Biophysical Journal 88 880 902
    • (2005) Biophysical Journal , vol.88 , pp. 880-902
    • Wiggins, P.1    Philips, R.2
  • 33
    • 0030901623 scopus 로고    scopus 로고
    • Mechanosensitive channels of Escherichia coli: The MscL gene, protein, and activities
    • SI Sukharev P Blount B Martinac C Kung 1997 Mechanosensitive channels of Escherichia coli: The MscL gene, protein, and activities Annual Review of Physiology 59 633 657
    • (1997) Annual Review of Physiology , vol.59 , pp. 633-657
    • Sukharev, S.I.1    Blount, P.2    Martinac, B.3    Kung, C.4
  • 35
    • 0041929590 scopus 로고    scopus 로고
    • Structure and mechanism in prokaryotic mechanosensitive channels
    • E Perozo D Rees 2003 Structure and mechanism in prokaryotic mechanosensitive channels Current Opinion in Structural Biology 13 432 442
    • (2003) Current Opinion in Structural Biology , vol.13 , pp. 432-442
    • Perozo, E.1    Rees, D.2
  • 38
    • 33645962236 scopus 로고    scopus 로고
    • C-Terminal charged cluster of MscL, RKKEE, functions as a pH sensor
    • A Kloda A Ghazi B Martinac 2006 C-Terminal charged cluster of MscL, RKKEE, functions as a pH sensor Biophysical Journal 90 1992 1998
    • (2006) Biophysical Journal , vol.90 , pp. 1992-1998
    • Kloda, A.1    Ghazi, A.2    Martinac, B.3
  • 39
    • 0030477115 scopus 로고    scopus 로고
    • Towards an understanding of the structural and functional properties of MscL, a mechanosensitive channel in bacteria
    • P Blount SI Sukharev PC Moe SK Nagle C Kung 1996 Towards an understanding of the structural and functional properties of MscL, a mechanosensitive channel in bacteria Biology of the Cell 87 1 8
    • (1996) Biology of the Cell , vol.87 , pp. 1-8
    • Blount, P.1    Sukharev, S.I.2    Moe, P.C.3    Nagle, S.K.4    Kung, C.5
  • 40
    • 0031806920 scopus 로고    scopus 로고
    • Electromechanical coupling model of gating the large mechanosensitive ion channel (MscL) of Escherichia coli by mechanical force
    • LQ Gu WH Liu B Martinac 1998 Electromechanical coupling model of gating the large mechanosensitive ion channel (MscL) of Escherichia coli by mechanical force Biophysical Journal 74 2889 2902
    • (1998) Biophysical Journal , vol.74 , pp. 2889-2902
    • Gu, L.Q.1    Liu, W.H.2    Martinac, B.3
  • 41
    • 0032826458 scopus 로고    scopus 로고
    • Hydrophilicity of a single residue within MscL correlates with increased channel mechanosensitivity
    • K Yoshimura A Batiza M Schroeder P Blount C Kung 1999 Hydrophilicity of a single residue within MscL correlates with increased channel mechanosensitivity Biophysical Journal 77 1960 1972
    • (1999) Biophysical Journal , vol.77 , pp. 1960-1972
    • Yoshimura, K.1    Batiza, A.2    Schroeder, M.3    Blount, P.4    Kung, C.5
  • 42
    • 1942423623 scopus 로고    scopus 로고
    • Loss-of-function mutations at the rim of the funnel of mechanosensitive channel MscL
    • K Yoshimura T Nomura M Sokabe 2004 Loss-of-function mutations at the rim of the funnel of mechanosensitive channel MscL Biophysical Journal 86 2113 2120
    • (2004) Biophysical Journal , vol.86 , pp. 2113-2120
    • Yoshimura, K.1    Nomura, T.2    Sokabe, M.3
  • 43
    • 13544256609 scopus 로고    scopus 로고
    • Gain of function mutations reveal expanded intermediate states and a sequential action of two gates in MscL
    • A Anishkin CS Chiang S Sukharev 2005 Gain of function mutations reveal expanded intermediate states and a sequential action of two gates in MscL The Journal of General Physiology 125 155 170
    • (2005) The Journal of General Physiology , vol.125 , pp. 155-170
    • Anishkin, A.1    Chiang, C.S.2    Sukharev, S.3
  • 44
    • 0033957169 scopus 로고    scopus 로고
    • Contributions of the different extramembranous domains of the mechanosensitive ion channel MscL to its response to membrane tension
    • B Ajouz C Berrier M Besnard B Martinac A Ghazi 2000 Contributions of the different extramembranous domains of the mechanosensitive ion channel MscL to its response to membrane tension The Journal of Biological Chemistry 275 1015 1022
    • (2000) The Journal of Biological Chemistry , vol.275 , pp. 1015-1022
    • Ajouz, B.1    Berrier, C.2    Besnard, M.3    Martinac, B.4    Ghazi, A.5
  • 45
    • 1942487703 scopus 로고    scopus 로고
    • Purification and functional reconstitution of N- and C-halves of the MscL channel
    • KH Park C Berrier B Martinac A Ghazi 2004 Purification and functional reconstitution of N- and C-halves of the MscL channel Biophysical Journal 86 2129 2136
    • (2004) Biophysical Journal , vol.86 , pp. 2129-2136
    • Park, K.H.1    Berrier, C.2    Martinac, B.3    Ghazi, A.4
  • 46
    • 0037194760 scopus 로고    scopus 로고
    • Open channel structure of MscL and the gating mechanism of mechanosensitive channels
    • E Perozo DM Cortes P Sompornpisut A Kloda B Martinac 2002 Open channel structure of MscL and the gating mechanism of mechanosensitive channels Nature 418 942 948
    • (2002) Nature , vol.418 , pp. 942-948
    • Perozo, E.1    Cortes, D.M.2    Sompornpisut, P.3    Kloda, A.4    Martinac, B.5
  • 47
    • 28444478453 scopus 로고    scopus 로고
    • Conformational changes involved in MscL channel gating measured using FRET spectroscopy
    • B Corry P Rigby ZW Liu B Martinac 2005 Conformational changes involved in MscL channel gating measured using FRET spectroscopy Biophysical Journal 89 L49 L51
    • (2005) Biophysical Journal , vol.89
    • Corry, B.1    Rigby, P.2    Liu, Z.W.3    Martinac, B.4
  • 48
    • 0031463940 scopus 로고    scopus 로고
    • Mutations in a bacterial mechanosensitive channel change the cellular response to osmotic stress
    • P Blount MJ Schroeder C Kung 1997 Mutations in a bacterial mechanosensitive channel change the cellular response to osmotic stress The Journal of Biological Chemistry 272 32150 32157
    • (1997) The Journal of Biological Chemistry , vol.272 , pp. 32150-32157
    • Blount, P.1    Schroeder, M.J.2    Kung, C.3
  • 49
    • 34249651256 scopus 로고    scopus 로고
    • Cooperative gating and spatial organization of membrane proteins through elastic interactions
    • T Ursell KC Huang E Peterson R Phillips 2007 Cooperative gating and spatial organization of membrane proteins through elastic interactions Plos Computational Biology 3 803 812
    • (2007) Plos Computational Biology , vol.3 , pp. 803-812
    • Ursell, T.1    Huang, K.C.2    Peterson, E.3    Phillips, R.4
  • 50
    • 0000197372 scopus 로고    scopus 로고
    • Low amplitude motions in proteins from a single-parameter atomic analysis
    • MM Tirion 1996 Low amplitude motions in proteins from a single-parameter atomic analysis Physical Review Letters 77 1905 1908
    • (1996) Physical Review Letters , vol.77 , pp. 1905-1908
    • Tirion, M.M.1
  • 52
    • 18144418170 scopus 로고    scopus 로고
    • Protein structural change upon ligand binding: Linear response theory
    • M Ikeguchi J Ueno M Sato A Kidera 2005 Protein structural change upon ligand binding: Linear response theory Physical Review Letters 94 078102
    • (2005) Physical Review Letters , vol.94 , pp. 078102
    • Ikeguchi, M.1    Ueno, J.2    Sato, M.3    Kidera, A.4
  • 53
    • 0036786659 scopus 로고    scopus 로고
    • Molecular dynamics simulations of biomolecules (vol 9, pg 646, 2002)
    • M Karplus JA McCammon 2002 Molecular dynamics simulations of biomolecules (vol 9, pg 646, 2002) Nature Structural Biology 9 788 788
    • (2002) Nature Structural Biology , vol.9 , pp. 788-788
    • Karplus, M.1    McCammon, J.A.2
  • 54
    • 0141754098 scopus 로고    scopus 로고
    • Gating of MscL studied by steered molecular dynamics
    • J Gullingsrud K Schulten 2003 Gating of MscL studied by steered molecular dynamics Biophysical Journal 85 2087 2099
    • (2003) Biophysical Journal , vol.85 , pp. 2087-2099
    • Gullingsrud, J.1    Schulten, K.2
  • 55
    • 0035039272 scopus 로고    scopus 로고
    • Structural determinants of MscL gating studied by molecular dynamics simulations
    • J Gullingsrud D Kosztin K Schulten 2001 Structural determinants of MscL gating studied by molecular dynamics simulations Biophysical Journal 80 2074 2081
    • (2001) Biophysical Journal , vol.80 , pp. 2074-2081
    • Gullingsrud, J.1    Kosztin, D.2    Schulten, K.3
  • 56
    • 43649090741 scopus 로고    scopus 로고
    • Gating of the mechanosensitive channel protein MscL: The interplay of membrane and protein
    • J Jeon GA Voth 2008 Gating of the mechanosensitive channel protein MscL: The interplay of membrane and protein Biophysical Journal 94 3497 3511
    • (2008) Biophysical Journal , vol.94 , pp. 3497-3511
    • Jeon, J.1    Voth, G.A.2
  • 57
    • 0027794972 scopus 로고
    • Targeted molecular-dynamics simulation of conformational change-application to the T&R transition insulin
    • J Schlitter M Engels P Kruger E Jacoby A Wollmer 1993 Targeted molecular-dynamics simulation of conformational change-application to the T&R transition insulin Molecular Simulation 10 291 308
    • (1993) Molecular Simulation , vol.10 , pp. 291-308
    • Schlitter, J.1    Engels, M.2    Kruger, P.3    Jacoby, E.4    Wollmer, A.5
  • 59
    • 0037070165 scopus 로고    scopus 로고
    • Molecular simulations of the large conductance mechanosensitive (MscL) channel under mechanical loading
    • LE Bilston K Mylvaganam 2002 Molecular simulations of the large conductance mechanosensitive (MscL) channel under mechanical loading FEBS Letters 512 185 190
    • (2002) FEBS Letters , vol.512 , pp. 185-190
    • Bilston, L.E.1    Mylvaganam, K.2
  • 60
    • 33748451900 scopus 로고    scopus 로고
    • Molecular dynamics study of MscL interactions with a curved lipid bilayer
    • GR Meyer J Gullingsrud K Schulten B Martinac 2006 Molecular dynamics study of MscL interactions with a curved lipid bilayer Biophysical Journal 91 1630 1637
    • (2006) Biophysical Journal , vol.91 , pp. 1630-1637
    • Meyer, G.R.1    Gullingsrud, J.2    Schulten, K.3    Martinac, B.4
  • 61
    • 42449087270 scopus 로고    scopus 로고
    • New insights of membrane environment effects on MscL channel mechanics from theoretical approaches
    • G Debret H Valadié AM Stadler C Etchebest 2008 New insights of membrane environment effects on MscL channel mechanics from theoretical approaches Proteins 71 1183 1196
    • (2008) Proteins , vol.71 , pp. 1183-1196
    • Debret, G.1    Valadié, H.2    Stadler, A.M.3    Etchebest, C.4
  • 63
    • 33748266722 scopus 로고    scopus 로고
    • Mixed atomistic and coarse-grained molecular dynamics: Simulation of a membrane-bound ion channel
    • Q Shi S Izvekov GA Voth 2006 Mixed atomistic and coarse-grained molecular dynamics: Simulation of a membrane-bound ion channel The Journal of Physical Chemistry B 110 15045 15048
    • (2006) The Journal of Physical Chemistry B , vol.110 , pp. 15045-15048
    • Shi, Q.1    Izvekov, S.2    Voth, G.A.3
  • 66
    • 33644929350 scopus 로고    scopus 로고
    • Multiscale coarse graining of liquid-state systems
    • S Izvekov GA Voth 2005 Multiscale coarse graining of liquid-state systems Journal of Chemical Physics 123 134105
    • (2005) Journal of Chemical Physics , vol.123 , pp. 134105
    • Izvekov, S.1    Voth, G.A.2
  • 67
    • 58549090393 scopus 로고    scopus 로고
    • ABAQUS Providence, Rhode Island: ABAQUS Inc.
    • ABAQUS (2004) Abaqus 6.4 user's manual 2004. Providence, Rhode Island: ABAQUS Inc.
    • (2004) Abaqus 6.4 User's Manual 2004
  • 69
    • 36849120197 scopus 로고
    • On the stresses in a plate containing 2 circular holes
    • CB Ling 1948 On the stresses in a plate containing 2 circular holes Journal of Applied Physics 19 77 81
    • (1948) Journal of Applied Physics , vol.19 , pp. 77-81
    • Ling, C.B.1
  • 72
    • 58549102585 scopus 로고    scopus 로고
    • Stress and strain in a yeast cell under high hydrostatic pressure
    • C Hartmann A Delgado 2004 Stress and strain in a yeast cell under high hydrostatic pressure PAMM 4 316 317
    • (2004) PAMM , vol.4 , pp. 316-317
    • Hartmann, C.1    Delgado, A.2
  • 74
    • 58549118319 scopus 로고    scopus 로고
    • Sanner, M. (2008). http://Www.Scripps.Edu/~Sanner/Html/Msms-Home.Html.
    • (2008)
    • Sanner, M.1
  • 75
    • 39749171104 scopus 로고    scopus 로고
    • A finite element framework for computation of protein normal modes and mechanical response
    • M Bathe 2008 A finite element framework for computation of protein normal modes and mechanical response Proteins-Structure Function and Bioinformatics 70 1595 1609
    • (2008) Proteins-Structure Function and Bioinformatics , vol.70 , pp. 1595-1609
    • Bathe, M.1
  • 77
    • 1942456697 scopus 로고    scopus 로고
    • Recent advances in the development and application of implicit solvent models in biomolecule simulations
    • M Feig CL Brooks 2004 Recent advances in the development and application of implicit solvent models in biomolecule simulations Current Opinion in Structural Biology 14 217 224
    • (2004) Current Opinion in Structural Biology , vol.14 , pp. 217-224
    • Feig, M.1    Brooks, C.L.2
  • 78
    • 37449015088 scopus 로고    scopus 로고
    • A nonlinear elasticity model of macromolecular conformational change induced by electrostatic forces
    • YC Zhou M Holst JA McCammon 2008 A nonlinear elasticity model of macromolecular conformational change induced by electrostatic forces Journal of Mathematical Analysis and Applications 340 135 164
    • (2008) Journal of Mathematical Analysis and Applications , vol.340 , pp. 135-164
    • Zhou, Y.C.1    Holst, M.2    McCammon, J.A.3
  • 79
    • 36849026098 scopus 로고    scopus 로고
    • Straightening and sequential buckling of the pore-lining helices define the gating cycle of MscS
    • B Akitake A Anishkin N Liu S Sukharev 2007 Straightening and sequential buckling of the pore-lining helices define the gating cycle of MscS Nature Structural & Molecular Biology 14 1141 1149
    • (2007) Nature Structural & Molecular Biology , vol.14 , pp. 1141-1149
    • Akitake, B.1    Anishkin, A.2    Liu, N.3    Sukharev, S.4
  • 82
    • 33846849245 scopus 로고    scopus 로고
    • Disulfide trapping the mechanosensitive channel MscL into a gating-transition state
    • IGL Iscla R Wray P Blount 2007 Disulfide trapping the mechanosensitive channel MscL into a gating-transition state Biophysical Journal 92 1224 1232
    • (2007) Biophysical Journal , vol.92 , pp. 1224-1232
    • Iscla, I.G.L.1    Wray, R.2    Blount, P.3
  • 83
    • 40849083928 scopus 로고    scopus 로고
    • Pressure-driven water infiltration into carbon nanotube: The effect of applied charges
    • L Liu Y Qiao X Chen 2008 Pressure-driven water infiltration into carbon nanotube: The effect of applied charges Applied Physics Letters 92 101927
    • (2008) Applied Physics Letters , vol.92 , pp. 101927
    • Liu, L.1    Qiao, Y.2    Chen, X.3
  • 84
    • 47949089584 scopus 로고    scopus 로고
    • Effects of addition of electrolyte on liquid infiltration in a hydrophobic nanoporous silica gel
    • A Han X Chen Y Qiao 2008 Effects of addition of electrolyte on liquid infiltration in a hydrophobic nanoporous silica gel Langmuir 24 7044 7047
    • (2008) Langmuir , vol.24 , pp. 7044-7047
    • Han, A.1    Chen, X.2    Qiao, Y.3
  • 88
    • 34047118099 scopus 로고    scopus 로고
    • Microbial TRP channels and their mechanosensitivity
    • O. P. Hamill (Ed.) Boston: Academic Press.
    • Saimi, Y., Zhou, X. L., Loukin, S. H., Haynes, W. J., and Kung, C. (2007). Microbial TRP channels and their mechanosensitivity, In: O. P. Hamill (Ed.), Mechanosensitive Ion Channels, Part A (pp. 311-327). Boston: Academic Press.
    • (2007) Mechanosensitive Ion Channels, Part A , pp. 311-327
    • Saimi, Y.1    Zhou, X.L.2    Loukin, S.H.3    Haynes, W.J.4    Kung, C.5
  • 90
    • 23244456428 scopus 로고    scopus 로고
    • Crystal structure of a mammalian voltage-dependent Shaker family K+ channel
    • SB Long EB Campbell R MacKinnon 2005 Crystal structure of a mammalian voltage-dependent Shaker family K+ channel Science 309 897 903
    • (2005) Science , vol.309 , pp. 897-903
    • Long, S.B.1    Campbell, E.B.2    MacKinnon, R.3
  • 91
    • 23244441222 scopus 로고    scopus 로고
    • Voltage sensor of kv1.2: Structural basis of electromechanical coupling
    • SB Long EB Campbell R MacKinnon 2005 Voltage sensor of kv1.2: Structural basis of electromechanical coupling Science 309 903 908
    • (2005) Science , vol.309 , pp. 903-908
    • Long, S.B.1    Campbell, E.B.2    MacKinnon, R.3
  • 92
    • 2242431668 scopus 로고    scopus 로고
    • Crystal structure of Escherichia coli MscS, a voltage-modulated and mechanosensitive channel
    • RB Bass P Strop MT Barclay DC Rees 2002 Crystal structure of Escherichia coli MscS, a voltage-modulated and mechanosensitive channel Science 298 1582 1587
    • (2002) Science , vol.298 , pp. 1582-1587
    • Bass, R.B.1    Strop, P.2    Barclay, M.T.3    Rees, D.C.4
  • 93
    • 2142715470 scopus 로고    scopus 로고
    • Water dynamics and dewetting transition in the small mechanosensitive channel MscS
    • A Anishkin S Sukharev 2004 Water dynamics and dewetting transition in the small mechanosensitive channel MscS Biophysical Journal 86 2883 2895
    • (2004) Biophysical Journal , vol.86 , pp. 2883-2895
    • Anishkin, A.1    Sukharev, S.2
  • 94
    • 33646200263 scopus 로고    scopus 로고
    • Voltage-dependent hydration and conduction properties of the hydrophobic pore of the mechanosensitive channel of small conductance
    • SA Spronk DE Elmore DA Dougherty 2006 Voltage-dependent hydration and conduction properties of the hydrophobic pore of the mechanosensitive channel of small conductance Biophysical Journal 90 3555 3569
    • (2006) Biophysical Journal , vol.90 , pp. 3555-3569
    • Spronk, S.A.1    Elmore, D.E.2    Dougherty, D.A.3
  • 95
    • 33846828514 scopus 로고    scopus 로고
    • Ion conduction through MscS as determined by electrophysiology and simulation
    • M Sotomayor V Vasquez E Perozo K Schulten 2007 Ion conduction through MscS as determined by electrophysiology and simulation Biophysical Journal 92 886 902
    • (2007) Biophysical Journal , vol.92 , pp. 886-902
    • Sotomayor, M.1    Vasquez, V.2    Perozo, E.3    Schulten, K.4
  • 99
    • 33244458728 scopus 로고    scopus 로고
    • Gating prokaryotic mechanosensitive channels
    • E Perozo 2006 Gating prokaryotic mechanosensitive channels Nature Reviews Molecular Cell Biology 7 109 119
    • (2006) Nature Reviews Molecular Cell Biology , vol.7 , pp. 109-119
    • Perozo, E.1
  • 100
    • 0025114667 scopus 로고
    • Mechanosensitive ion channels of E. coli activated by amphipaths
    • B Martinac J Adler C Kung 1990 Mechanosensitive ion channels of E. coli activated by amphipaths Nature 348 261 263
    • (1990) Nature , vol.348 , pp. 261-263
    • Martinac, B.1    Adler, J.2    Kung, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.