Hepatic translation control in the late-gestation fetal rat

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 295, Issue 2, 2008, Pages

  Gruppuso, Philip A ^a,b   Tsai, Shu Whei ^a   Boylan, Joan M ^a   Sanders, Jennifer A ^a  

^a BROWN UNIVERSITY   (United States)

^b RHODE ISLAND HOSPITAL   (United States)

Author keywords

Hepatocyte; Liver; Mammalian target of rapamycin; Ribosome; Signal transduction

Indexed keywords

INITIATION FACTOR 4A; INITIATION FACTOR 4A 1; INITIATION FACTOR 4A 2; INITIATION FACTOR 4F; MAMMALIAN TARGET OF RAPAMYCIN; RAPAMYCIN; UNCLASSIFIED DRUG; INITIATION FACTOR 4G; MESSENGER RNA; PROTEIN KINASE; PROTEIN S6; PROTEIN SYNTHESIS INHIBITOR; RIBOSOME PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; FETUS; FETUS LIVER; GESTATIONAL AGE; LIVER CELL; LIVER DEVELOPMENT; MALE; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REFEEDING; RNA TRANSLATION; SIGNAL TRANSDUCTION; TERMINAL OLIGOPYRIMIDINE TRACT; TRANSLATION REGULATION; ANIMAL; COMPARATIVE STUDY; DRUG EFFECT; EATING; ENZYMOLOGY; FOOD DEPRIVATION; GENE EXPRESSION REGULATION; GENETICS; LIVER; LIVER REGENERATION; LIVER RESECTION; METABOLISM; PREGNANCY; PRENATAL DEVELOPMENT; PROTEIN SYNTHESIS; SPRAGUE DAWLEY RAT; TIME;

ANIMALS; CELL PROLIFERATION; EATING; EUKARYOTIC INITIATION FACTOR-4A; EUKARYOTIC INITIATION FACTOR-4F; EUKARYOTIC INITIATION FACTOR-4G; FEMALE; FOOD DEPRIVATION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GESTATIONAL AGE; HEPATECTOMY; LIVER; LIVER REGENERATION; MALE; PREGNANCY; PROTEIN BIOSYNTHESIS; PROTEIN KINASES; PROTEIN SYNTHESIS INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY; RIBOSOMAL PROTEIN S6; RIBOSOMAL PROTEINS; RNA 5' TERMINAL OLIGOPYRIMIDINE SEQUENCE; RNA, MESSENGER; SIGNAL TRANSDUCTION; SIROLIMUS; TIME FACTORS;

EID: 51149121232     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00091.2008     Document Type: Article

References (45)

1. Anand P, Boylan JM, Ou Y, Gruppuso PA. Insulin signaling during perinatal liver development in the rat. Am J Physiol Endocrinol Metab 283: E844-E852, 2002.
2. Anand P, Gruppuso PA. The regulation of hepatic protein synthesis during fasting in the rat. J Biol Chem 280: 16427-16436, 2005.
3. Anand P, Gruppuso PA. Rapamycin inhibits liver growth during refeeding in rats via control of ribosomal protein translation but not cap-dependent translation initiation. J Nutr 136: 27-33, 2006.
4. Awad MM, Sanders JA, Gruppuso PA. A potential role for p15(Ink4b) and p57(Kip2) in liver development. FEBS Lett 483: 160-164, 2000.
5. Bolster DR, Vary TC, Kimball SR, Jefferson LS. Leucine regulates translation initiation in rat skeletal muscle via enhanced eIF4G phosphorylation. J Nutr 134: 1704-1710, 2004.
6. Boylan JM, Anand P, Gruppuso PA. Ribosomal protein S6 phosphorylation and function during late gestation liver development in the rat. J Biol Chem 276: 44457-44463, 2001.
7. 2-terminal kinase pathways in the late-gestation fetal rat. Cell Growth Diff 7: 1261-1269, 1996.
8. Boylan JM, Gruppuso PA. Uncoupling of hepatic, epidermal growth factor-mediated mitogen-activated protein kinase activation in the fetal rat. J Biol Chem 273: 3784-3790, 1998.
9. Boylan JM, Gruppuso PA. D-type cyclins and G1 progression during liver development in the rat. Biochem Biophys Res Commun 330: 722-730, 2005.
10. Caron S, Charon M, Cramer E, Sonenberg N, Dusanter-Fourt I. Selective modification of eukaryotic initiation factor 4F (eIF4F) at the onset of cell differentiation: recruitment of eIF4GII and long-lasting phosphorylation of eIF4E. Mol Cell Biol 24: 4920-4928, 2004.
11. Castello A, Alvarez E, Carrasco L. Differential cleavage of eIF4GI and eIF4GII in mammalian cells. Effects on translation. J Biol Chem 281: 33206-33216, 2006.
12. Coldwell MJ, Morley SJ. Specific isoforms of translation initiation factor 4GI show differences in translational activity. Mol Cell Biol 26: 8448-8460, 2006.
13. Dabeva MD, Petkov PM, Sandhu J, Oren R, Laconi E, Hurston E, Shafritz DA. Proliferation and differentiation of fetal liver epithelial progenitor cells after transplantation into adult rat liver. Am J Pathol 156: 2017-2031, 2000.
14. Dolznig H, Grebien F, Sauer T, Beug H, Mullner EW. Evidence for a size-sensing mechanism in animal cells. Nat Cell Biol 6: 899-905, 2004.
15. Embree-Ku M, Gruppuso PA. The role of nuclear factor kappaB in late-gestation liver development in the rat. Hepatology 42: 326-334, 2005.
16. Fingar DC, Blenis J. Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression. Oncogene 23: 3151-3171, 2004.
17. Gingras AC, Raught B, Sonenberg N. mTOR signaling to translation. Curr Top Microbiol Immunol 279: 169-197, 2004.
18. Goggin MM, Nelsen CJ, Kimball SR, Jefferson LS, Morley SJ, Albrecht JH. Rapamycin-sensitive induction of eukaryotic initiation factor 4F in regenerating mouse liver. Hepatology 40: 537-544, 2004.
19. Grebien F, Dolznig H, Beug H, Mullner EW. Cell size control: new evidence for a general mechanism. Cell Cycle 4: 418-421, 2005.
20. Gruppuso PA, Awad M, Bienieki TC, Boylan JM, Fernando S, Faris RA. Modulation of mitogen-independent hepatocyte proliferation during the perinatal period in the rat. In Vitro Cell Dev Biol Anim 33: 562-568, 1997.
21. Gruppuso PA, Bienieki TC, Faris RA. The relationship between differentiation and proliferation in late gestation fetal rat hepatocytes. Pediatr Res 46: 14-19, 1999.
22. Gruppuso PA, Brautigan DL. Induction of hepatic glycogenesis in the fetal rat. Am J Physiol Endocrinol Metab 256: E49-E54, 1989.
23. Gruppuso PA, Vaslet CA, Boylan JM. Identification of candidate growth-regulating genes that are over-expressed in late gestation fetal liver in the rat. Biochim Biophys Acta 1494: 242-247, 2000.
24. Hamilton TL, Stoneley M, Spriggs KA, Bushell M. TOPs and their regulation. Biochem Soc Trans 34: 12-16, 2006.
25. Hay N, Sonenberg N. Upstream and downstream of mTOR. Genes Dev 18: 1926-1945, 2004.
26. Hinton TM, Coldwell MJ, Carpenter GA, Morley SJ, Pain VM. Functional analysis of individual binding activities of the scaffold protein eIF4G. J Biol Chem 282: 1695-1708, 2007.
27. Hornstein E, Tang H, Meyuhas O. Mitogenic and nutritional signals are transduced into translational efficiency of TOP mRNAs. Cold Spring Harbor Symp Quantit Biol LXVI: 477-484, 2001.
28. Hosoi H, Dilling MB, Liu LN, Danks JK, Shikata T, Sekulic A, Abraham RT, Lawrence JC, Houghton PJ. Studies on the mechanism of resistance to rapamycin in human cancer cells. Mol Pharmacol 54: 815-824, 1998.
29. s6k. EMBO J 16: 3693-3704, 1997.
30. Jiang YP, Ballou LM, Lin RZ. Rapamycin-insensitive regulation of 4E-BP1 in regenerating rat liver. J Biol Chem 276: 10943-10951, 2001.
31. Lawrence JC, Abraham RT. PHAS/4E-BPs as regulators of mRNA translation and cell proliferation. Trends Biochem Sci 22: 345-349, 1997.
32. Ling J, Morley SJ, Traugh JA. Inhibition of cap-dependent translation via phosphorylation of eIF4G by protein kinase Pak2. EMBO J 24: 4094-4105, 2005.
33. Montagne J, Stewart MJ, Stocker H, Hafen E, Kozma SC, Thomas G. Drosophila S6 kinase: a regulator of cell size. Science 285: 2126-2129, 1999.
34. Moss T. At the crossroads of growth control; making ribosomal RNA. Curr Opin Genet Dev 14: 210-217, 2004.
35. Nousch M, Reed V, Bryson-Richardson RJ, Currie PD, Preiss T. The eIF4G-homolog p97 can activate translation independent of caspase cleavage. RNA 13: 374-384, 2007.
36. Pause A, Methot N, Svitkin Y, Merrick WC, Sonenberg N. Dominant negative mutants of mammalian translation initiation factor eIF-4A define a critical role for eIF-4F in cap-dependent and cap-independent initiation of translation. EMBO J 13: 1205-1215, 1994.
37. Proud CG. Signalling to translation: how signal transduction pathways control the protein synthetic machinery. Biochem J 403: 217-234, 2007.
38. Richter JD, Sonenberg N. Regulation of cap-dependent translation by eIF4E inhibitory proteins. Nature 433: 477-480, 2005.
39. Ruggero D, Pandolfi PP. Does the ribosome translate cancer? Nat Rev Cancer 3: 179-192, 2003.
40. Ruvinsky I, Meyuhas O. Ribosomal protein S6 phosphorylation: from protein synthesis to cell size. Trends Biochem Sci 31: 342-348, 2006.
41. Ruvinsky I, Sharon N, Lerer T, Cohen H, Stolovich-Rain M, Nir T, Dor Y, Zisman P, Meyuhas O. Ribosomal protein S6 phosphorylation is a determinant of cell size and glucose homeostasis. Genes Dev 19: 2199-2211, 2005.
42. Umen JG. The elusive sizer. Curr Opin Cell Biol 17: 435-441, 2005.
43. Williams-Hill DM, Duncan RF, Nielsen PJ, Tahara SM. Differential expression of the murine eukaryotic translation initiation factor isogenes eIF4A(I) and eIF4A(II) is dependent upon cellular growth status. Arch Biochem Biophys 338: 111-120, 1997.
44. Yoo SJ, Jimenez RH, Sanders JA, Boylan JM, Brautigan DL, Gruppuso PA. The α4-containing form of protein phosphatase 2A in liver and hepatic cells. J Cell Biochem In press.
45. Zakowicz H, Yang HS, Stark C, Wlodawer A, Laronde-Leblanc N, Colburn NH. Mutational analysis of the DEAD-box RNA helicase eIF4AII characterizes its interaction with transformation suppressor Pdcd4 and eIF4GI. RNA 11: 261-274, 2005.