A comparative study of the hepatic mitogen-activated protein kinase and Jun-NH2-terminal kinase pathways in the late-gestation fetal rat

Cell Growth and Differentiation

Volumn 7, Issue 9, 1996, Pages 1261-1269

  Boylan, Joan M ^a   Gruppuso, Philip A ^a,b  

^a BROWN UNIVERSITY   (United States)

^b RHODE ISLAND HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; TRANSFORMING GROWTH FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; ENZYME ACTIVATION; ENZYME ACTIVITY; FETUS; FETUS DEVELOPMENT; GROWTH REGULATION; LIVER CELL; LIVER DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL DIVISION; CELLS, CULTURED; ENZYME ACTIVATION; EPIDERMAL GROWTH FACTOR; FEMALE; GESTATIONAL AGE; GRB2 ADAPTOR PROTEIN; HEPATOCYTE GROWTH FACTOR; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIVER; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PREGNANCY; PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR ALPHA; TUMOR NECROSIS FACTOR-ALPHA; TYROSINE;

ANIMALIA;

EID: 0029827324     PISSN: 10449523     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Davis, R. J. MAPKs: new JNK expands the group. Trends. Biochem. Sci., 19: 470-473, 1994.
2. Hibi, M., Lin, A., Smeal, T., Minden, A., and Karin, M. Identification of an oncoprotein and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain. Genes Dev., 7: 2135-2148, 1993.
3. Derijard, B., Hibi, M., Wu, I. H., Barrett, T., Su, B., Deng, T., Karin, M., and Davis, R. J. JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell 76: 1025-1037, 1994.
4. Kyriakis, J. M., Banerjee, P., Nikolakaki, E., Dai, T., Rubie, E. A., Ahmad, M. F., Avruch, J., and Woodgett, J. R. The stress-activated protein kinase subfamily of c-Jun kinases. Nature (Lond.), 369: 156-160, 1994.
5. Crews, C. M., and Erickson, R. L. Extracellular signals and reversible protein phosphorylation: what to mek of it all. Cell, 74: 215-217, 1993.
6. Cobb, M. H., and Goldsmith, E. J. How MAP kinases are regulated. J. Biol. Chem., 270: 14843-14846, 1995.
7. Hall, A. A biochemical function for Ras - at last. Science (Washington DC), 264: 1413-1414, 1994.
8. Yao, B. Zhang, Y., Delikat, S., Mathias, S., Basu, S., and Kolesnick, R. Phosphorylation of Raf by ceramide-activated protein kinase. Nature (Lond.), 378: 307-310, 1995.
9. Coso, O. A., Chiariello, M., Yu, J-C., Teramoto, H., Crespo, P., Xu, N., Miki, T., and Gutkind, J. S. The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway. Cell, 81: 1137-1146, 1995.
10. Minden, A., Lin, A., Claret, F-X., Abo, A., and Karin, M. Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs. Cell, 87: 1147-1157, 1995.
11. Gruppuso, P. A., Curran, T. R., Mead, J. E., Fausto, N., and Oh, W. Fetal growth factors as determinants of intrauterine hepatic growth. Diabetes, 40 (Suppl. 2): 51-55, 1991.
12. Gruppuso, P. A., Curran, T. R., and Bahner, R. I. Fetal growth factors. In: E. Herrera, and R. H. Knopp, (eds.), Perinatal Biochemistry, pp. 194-210. Boca Raton, FL: CRC Press, Inc., 1992.
13. Curran, T. R., Bahner, R. I., Oh, W., and Gruppuso, P. A. Mitogen-independent DNA synthesis by fetal rat hepatocytes in primary culture. Exp. Cell. Res., 209: 53-57, 1993.
14. Boylan, J. M., and Gruppuso, P. A. In vitro and in vivo regulation of hepatic mitogen-activated protein kinases in fetal rats. Am. J. Physiol., 267: G1078-G1086, 1994.
15. Westwick, J. K., Weitzel, C., Leffert, H. L., and Brenner, D. A. Activation of Jun kinase is an early event in hepatic regeneration. J. Clin. Invest., 95: 803-810, 1995.
16. Gruppuso, P. A., Boylan, J. M., Bienieki, T. C., and Curran, T. R. Evidence for a direct hepatotrophic role for insulin in the fetal rat: implications for the impaired hepatic growth seen in fetal growth retardation. Endocrinology, 134: 769-775, 1994.
17. Stevenson, L. E., Santos-Moore, A., Clark, J. W., and Frackelton, A. R. In breast cancer cells, the Shc adapter protein is tyrosine phosphorylated in the presence of EGF-receptor neutralizing Ab. Proc. Am. Assoc. Cancer Res., 36: 60, 1995.
18. Adamson, E. D. Growth factors and their receptors in development. Dev. Genet., 14: 159-164, 1993.
19. Gruppuso, P. A. Expression of hepatic transforming growth factor receptors during late gestation in the fetal rat. Endocrinology, 125: 3037-3043, 1989.
20. Gruppuso, P. A., Walker, T. D., and Carter, P. A. Ontogeny of hepatic type I insulin-like growth factor receptors in the rat. Pediatr. Res., 29: 226-230, 1991.
21. Gruppuso, P. A., Boylan, J. M., Carter, P. A., Madden, J. A., and Raven, T. Hepatic insulin and EGF receptor phosphorylation and dephosphorylation in the fetal rat. Am. J. Physiol., 262: E6-E13, 1992.
22. Diehl, A. M., Yin, M., Fleckenstein, J., Yang, S. Q., Lin, H. Z., Brenner, D. A., Westwick, J., Bagby, G., and Nelson, S. Tumor necrosis factor-α during the regenerative response to liver injury. Am. J. Physiol., 267: G552-G561, 1994.
23. Diehl, A. M., Yang, S. Q., Yin, M., Lin, H. Z., Nelson, S., and Bagby, G. Tumor necrosis factor-α modulates CCAAT/enhancer binding proteins-DNA binding activities and promotes hepatocyte-specific gene expression during liver regeneration. Hepatology, 22: 252-261, 1995.
24. Tobe, K., Kadowaki, T., Hara, K., Gotoh, Y., Kosako, H., Matsuda, S., Tamemoto, H., Euki, K., Akanuma, Y., Nishida, E., and Yazak, Y. Sequential activation of MAP kinase activator, MAP kinases, and S6 peptide kinase in intact rat liver following insulin injection. J. Biol. Chem., 267: 21089-21097, 1992.
25. Peak, M., Yeaman, S. J., and Agius, L. Epidermal growth factor and insulin stimulate MAP kinase activity in cultured hepatocytes. Biochem. Soc. Trans., 21: 494S, 1993.
26. Pelicci, G., Lanfrancone, L., Grignani, F., McGlade, J., Cavallo, F., Forni, G., Nicoletti, I., Grignani, F., Pawson, T., and Pelicci, P. G. A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction. Cell, 70: 93-104, 1992.
27. Gotoh, N., Tojo, A., Muroya, K., Hashimoto, Y., Hattori, S., Nakamura, S., Takenawa, T., Yazaki, Y., and Shibuya, M. Epidermal growth factor-receptor mutant lacking the autophosphorylation sites induces phosphorylation of Shc protein and Shc-Grb2/ASH association and retains mitogenic activity. Proc. Natl. Acad. Sci. USA, 91: 167-171, 1994.
28. Sasaoka, T., Rose, D. W., Jhun, B. H., Saltiel, A. R., Draznin, B., and Olefsky, J. M. Evidence for a functional role of Shc proteins in mitogenic signaling induced by insulin, insulin-like growth factor-1, and epidermal growth factor. J. Biol. Chem., 269: 13689-13694, 1994.
29. Pronk, G. J., DeVries-Smits, A. M. M., Buday, L., Downward, J., Maassen, J. A., Medema, R. H., and Bos, J. L. Involvement of Shc in insulin- and epidermal growth factor-induced activation of p21ras. Mol. Cell. Biol., 14: 1575-1581, 1994.
30. Schlessinger, J., and Bar-Sagi, D. Activation of Ras and other signaling pathways by receptor tyrosine kinases. Cold Spring Harbor Symp. Quant. Biol., 59: 173-179, 1994.
31. Ravichandran, K. S., Lorenz, U., Shoelson, S. E., and Burakoff, S. J. Interaction of Shc with Grb2 regulates association of Grb2 with mSOS. Mol. Cell. Biol., 15: 593-600, 1995.
32. Minden, A., Lin, A., McMahon, M., Lange-Carter, C., Derijard, B., Davis, R. J., Johnson, G. L., and Karin, M. Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK. Science (Washington DC), 266: 1719-1723, 1994.
33. Westwick, J. D., Cox, A. D., Der, C. J., Cobb, M. H., Hibi, M., Karin, M., and Brenner, D. A. Oncogenic Ras activates c-Jun via a separate pathway from the activation of extracellular signal-regulated kinases. Proc. Natl. Acad. Sci. USA, 91: 6030-6034, 1994.
34. Smeal, T., Binetruy, B., Mercola, D. A., Birrer, M., and Karin, M. Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73. Nature (Lond.), 354: 494-496, 1991.
35. DiGuglielmo, G. M., Baass, P. C., Ou, W-J., Posner, B. I., and Bergeron, J. J. M. Compartmentalization of SHC, GRB2 and mSOS, and hyperphosphorylation of Raf-1 by EGF but not insulin in liver parenchyma. EMBO J., 13: 4269-4277, 1994.
36. Ras desensitization by insulin. J. Biol. Chem., 270: 1485-1488, 1995.
37. ras activation. J. Biol. Chem., 270: 25320-25323, 1995.
38. Buday, L., Warne, P. H., and Downward, J. Downregulation of the ras activation pathway by MAP kinase phosphorylation of Sos. Oncogene, 11: 1327-1335, 1995.
39. Rozakis-Adcock, M., Van der Geer, P., Mbamalu, G., and Pawson, T., MAP kinase phosphorylation of mSos1 promotes dissociation of mSos1Shc and mSos1-EGF receptor complexes. Oncogene, 11: 1417-1423, 1995.
40. Sun, H., Charles, C. H., Lau, L. F., and Tonks, N. K. MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo. Cell, 75: 487-493, 1993.
41. Sun, H., Tonks, N. K., and Bar-Sagi, D. Inhibition of Ras-induced DNA synthesis by expression of the phosphatase MKP-1. Science (Washington DC), 266: 285-288, 1994.
42. Kwak, S. P., and Dixon, J. E. Multiple dual specificity protein tyrosine phosphatases are expressed and regulated differentially in liver cell lines. J. Biol. Chem., 270: 1156-1160, 1995.
43. Adler, V., Franklin, C. C., and Kraft, A. S. Phorbol esters stimulate the phosphorylation of c-Jun but not v-Jun: regulation of the N-terminal δ domain. Proc. Natl. Acad. Sci. USA, 89: 5341-5345, 1992.
44. Pulverer, B. J., Hughes, K., Franklin, C. C., Kraft, A. S., Leevers, S. J., and Woodget, J. R. Co-purification of nitrogen-activated protein kinases with phorbol ester-induced c-Jun kinase activity in U937 leukemic cells. Oncogene, 8: 407-415, 1993.