-
1
-
-
0036727746
-
Genetics, cytokines and human infectious disease: Lessons from weakly pathogenic mycobacteria and salmonellae
-
Ottenhoff, T. H., Verreck, F. A., Lichtenauer-Kaligis, E. G. Hoeve, M. A. Sanal, O. and van Dissel J. T., Genetics, cytokines and human infectious disease: lessons from weakly pathogenic mycobacteria and salmonellae. Nat. Genet 2002. 32: 97-105.
-
(2002)
Nat. Genet
, vol.32
, pp. 97-105
-
-
Ottenhoff, T.H.1
Verreck, F.A.2
Lichtenauer-Kaligis, E.G.3
Hoeve, M.A.4
Sanal, O.5
van Dissel, J.T.6
-
2
-
-
0037313578
-
Interleukin-12 and the regulation of innate resistance and adaptive immunity
-
Trinchieri, G., Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat. Rev. Immunol 2003. 3: 133-146.
-
(2003)
Nat. Rev. Immunol
, vol.3
, pp. 133-146
-
-
Trinchieri, G.1
-
3
-
-
0033638507
-
Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
-
Oppmann, B., Lesley, R., Blom, B., Timans, J. C., Xu, Y., Hunte, B., Vega, F. et al., Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12 . Immunity 2002. 13: 715-725.
-
(2002)
Immunity
, vol.13
, pp. 715-725
-
-
Oppmann, B.1
Lesley, R.2
Blom, B.3
Timans, J.C.4
Xu, Y.5
Hunte, B.6
Vega, F.7
-
4
-
-
12144288237
-
Human IL-23-producing type 1 macrophages promote but IL-10-producing type 2 macrophages subvert immunity to (myco)bacteria
-
Verreck, F. A., de Boer, T., Langenberg, D. M., Hoeve, M. A., Kramer, M., Vaisberg, M. E., Kastelein, R. et al., Human IL-23-producing type 1 macrophages promote but IL-10-producing type 2 macrophages subvert immunity to (myco)bacteria. Proc. Natl. Acad. Sci. USA 2004. 101: 4560-4565.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 4560-4565
-
-
Verreck, F.A.1
de Boer, T.2
Langenberg, D.M.3
Hoeve, M.A.4
Kramer, M.5
Vaisberg, M.E.6
Kastelein, R.7
-
5
-
-
0036604306
-
A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R
-
Parham, C., Chirica, M., Timans, J., Vaisberg, E., Travis, M., Cheung, J. and Pflanz, S., A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R. J. Immunol 2002. 168: 5699-5708.
-
(2002)
J. Immunol
, vol.168
, pp. 5699-5708
-
-
Parham, C.1
Chirica, M.2
Timans, J.3
Vaisberg, E.4
Travis, M.5
Cheung, J.6
Pflanz, S.7
-
6
-
-
0346752089
-
IL-12 receptor deficiency revisited: IL-23-mediated signaling is also impaired in human genetic IL-12 receptor beta1 deficiency
-
Hoeve, M. A., de Boer, T., Langenberg, D. M. Sanal, O., Verreck, F. A. and Ottenhoff, T. H., IL-12 receptor deficiency revisited: IL-23-mediated signaling is also impaired in human genetic IL-12 receptor beta1 deficiency. Eur. J. Immunol 2003. 33: 3393-3397.
-
(2003)
Eur. J. Immunol
, vol.33
, pp. 3393-3397
-
-
Hoeve, M.A.1
de Boer, T.2
Langenberg, D.M.3
Sanal, O.4
Verreck, F.A.5
Ottenhoff, T.H.6
-
7
-
-
0345358584
-
The IL-12 family of heterodimeric cytokines: New players in the regulation of T cell responses
-
Trinchieri, G., Pflanz, S. and Kastelein, R. A., The IL-12 family of heterodimeric cytokines: new players in the regulation of T cell responses. Immunity 2003. 19: 641-644.
-
(2003)
Immunity
, vol.19
, pp. 641-644
-
-
Trinchieri, G.1
Pflanz, S.2
Kastelein, R.A.3
-
8
-
-
0035877257
-
Ubiquitous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, routing, infertility, and premature death
-
Wiekowski, M. T., Leach, M. W., Evans, E. W., Sullivan, L., Chen, S. C., Vassileva, G., Bazan, J. F. et al., Ubiquitous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, routing, infertility, and premature death. J. Immunol 2001. 166: 7563-7570.
-
(2001)
J. Immunol
, vol.166
, pp. 7563-7570
-
-
Wiekowski, M.T.1
Leach, M.W.2
Evans, E.W.3
Sullivan, L.4
Chen, S.C.5
Vassileva, G.6
Bazan, J.F.7
-
9
-
-
0036677420
-
Experimental autoimmune encephalitis and inflammation in the absence of interleukin-12
-
Becher, B., Durell, B. G. and Noelle, R. J., Experimental autoimmune encephalitis and inflammation in the absence of interleukin-12. J. Clin. Invest 2002. 110: 493-497.
-
(2002)
J. Clin. Invest
, vol.110
, pp. 493-497
-
-
Becher, B.1
Durell, B.G.2
Noelle, R.J.3
-
10
-
-
0037434789
-
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
-
Cua, D. J., Sherlock, J., Chen, Y., Murphy, C. A., Joyce, B., Seymour, B., Lucian, L. et al., Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature 2003. 421: 744-748.
-
(2003)
Nature
, vol.421
, pp. 744-748
-
-
Cua, D.J.1
Sherlock, J.2
Chen, Y.3
Murphy, C.A.4
Joyce, B.5
Seymour, B.6
Lucian, L.7
-
11
-
-
0037114150
-
IL-12p35-deficient mice are susceptible to experimental autoimmune encephalomyelitis: Evidence for redundancy in the IL-12 system in the induction of central nervous system autoimmune demyelination
-
Gran, B., Zhang, G. X., Yu, S., Li, J., Chen, X. H., Ventura, E. S., Kamoun, M. et al., IL-12p35-deficient mice are susceptible to experimental autoimmune encephalomyelitis: evidence for redundancy in the IL-12 system in the induction of central nervous system autoimmune demyelination. J. Immunol 2002. 169: 7104-7110.
-
(2002)
J. Immunol
, vol.169
, pp. 7104-7110
-
-
Gran, B.1
Zhang, G.X.2
Yu, S.3
Li, J.4
Chen, X.H.5
Ventura, E.S.6
Kamoun, M.7
-
12
-
-
0346962972
-
Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation
-
Murphy, C. A., Langrish, C. L. Chen, Y., Blumenschein, W., McClanahan, T., Kastelein, R. A., Sedgwick, J. D. et al., Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation. J. Exp. Med 2003. 198: 1951-1957.
-
(2003)
J. Exp. Med
, vol.198
, pp. 1951-1957
-
-
Murphy, C.A.1
Langrish, C.L.2
Chen, Y.3
Blumenschein, W.4
McClanahan, T.5
Kastelein, R.A.6
Sedgwick, J.D.7
-
13
-
-
0037442020
-
Induction of experimental autoimmune encephalomyelitis in IL-12 receptor-beta 2-deficient mice: IL-12 responsiveness is not required in the pathogenesis of inflammatory demyelination in the central nervous system
-
Zhang, G. X., Gran, B., Yu, S., Li, J., Siglienti, I., Chen, X., Kamoun, M. and Rostami, A., Induction of experimental autoimmune encephalomyelitis in IL-12 receptor-beta 2-deficient mice: IL-12 responsiveness is not required in the pathogenesis of inflammatory demyelination in the central nervous system. J. Immunol 2003. 170: 2153-2160.
-
(2003)
J. Immunol
, vol.170
, pp. 2153-2160
-
-
Zhang, G.X.1
Gran, B.2
Yu, S.3
Li, J.4
Siglienti, I.5
Chen, X.6
Kamoun, M.7
Rostami, A.8
-
14
-
-
10744230574
-
Role of IL-12 receptor beta 1 in regulation of T cell response by APC in experimental autoimmune encephalomyelitis
-
Zhang, G. X., Yu, S., Gran, B., Li, J., Siglienti, I., Chen, X., Calida, D. et al., Role of IL-12 receptor beta 1 in regulation of T cell response by APC in experimental autoimmune encephalomyelitis. J. Immunol 2003. 171: 4485-4492.
-
(2003)
J. Immunol
, vol.171
, pp. 4485-4492
-
-
Zhang, G.X.1
Yu, S.2
Gran, B.3
Li, J.4
Siglienti, I.5
Chen, X.6
Calida, D.7
-
15
-
-
0037449737
-
Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17
-
Aggarwal, S., Ghilardi, N., Xie, M. H., de Sauvage, F. J. and Gurney, A. L., Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17. J. Biol. Chem 2003. 278: 1910-1914.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 1910-1914
-
-
Aggarwal, S.1
Ghilardi, N.2
Xie, M.H.3
de Sauvage, F.J.4
Gurney, A.L.5
-
16
-
-
0028858556
-
Human IL-17: A novel cytokine derived from T cells
-
Yao, Z., Painter, S. L. Fanslow, W. C., Ulrich, D., Macduff, B. M., Spriggs, M. K. and Armitage, R. J., Human IL-17: a novel cytokine derived from T cells. J. Immunol. 1995. 155: 5483-5486.
-
(1995)
J. Immunol.
, vol.155
, pp. 5483-5486
-
-
Yao, Z.1
Painter, S.L.2
Fanslow, W.C.3
Ulrich, D.4
Macduff, B.M.5
Spriggs, M.K.6
Armitage, R.J.7
-
17
-
-
0036144194
-
IL-17: Prototype member of an emerging cytokine family
-
Aggarwal, S. and Gurney, A. L., IL-17: prototype member of an emerging cytokine family. J. Leukoc. Biol. 2002. 71: 1-8.
-
(2002)
J. Leukoc. Biol.
, vol.71
, pp. 1-8
-
-
Aggarwal, S.1
Gurney, A.L.2
-
18
-
-
0037333960
-
Interleukin-17 in rheumatoid arthritis: If T cells were to contribute to inflammation and destruction through synergy
-
Miossec, P., Interleukin-17 in rheumatoid arthritis: if T cells were to contribute to inflammation and destruction through synergy. Arthritis Rheum 2003. 48: 594-601.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 594-601
-
-
Miossec, P.1
-
19
-
-
15844402155
-
T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines
-
Fossiez, F., Djossou, O., Chomarat, P., FloresRomo, L., AitYahia, S., Maat, C., Pin, J. J. et al., T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines. J. Exp. Med 1996. 183: 2593-2603.
-
(1996)
J. Exp. Med
, vol.183
, pp. 2593-2603
-
-
Fossiez, F.1
Djossou, O.2
Chomarat, P.3
FloresRomo, L.4
AitYahia, S.5
Maat, C.6
Pin, J.J.7
-
21
-
-
0033083111
-
IL-17 is produced by some proinflammatory Th1/Th0 cells but not by Th2 cells
-
Aarvak, T., Chabaud, M., Miossec, P. and Natvig, J. B., IL-17 is produced by some proinflammatory Th1/Th0 cells but not by Th2 cells. J. Immunol 1999. 162: 1246-1251.
-
(1999)
J. Immunol
, vol.162
, pp. 1246-1251
-
-
Aarvak, T.1
Chabaud, M.2
Miossec, P.3
Natvig, J.B.4
-
22
-
-
0032939560
-
IL-17 is produced by nickel-specific T lymphocytes and regulates ICAM-1 expression and chemokine production in human keratinocytes: Synergistic or antagonist effects with IFN-gamma and TNF-alpha
-
Albanesi, C., Cavani, A. and Girolomoni, G., IL-17 is produced by nickel-specific T lymphocytes and regulates ICAM-1 expression and chemokine production in human keratinocytes: Synergistic or antagonist effects with IFN-gamma and TNF-alpha. J. Immunol. 1999. 162: 494-502.
-
(1999)
J. Immunol.
, vol.162
, pp. 494-502
-
-
Albanesi, C.1
Cavani, A.2
Girolomoni, G.3
-
23
-
-
0033911218
-
Interleukin-17 is produced by both Th1 and Th2 lymphocytes, and modulates interferon-gamma- and interleukin-4-induced activation of human keratinocytes
-
Albanesi, C., Scarponi, C. S., Cavani, A., Federici, M., Nasorri, F. and Girolomoni, G., Interleukin-17 is produced by both Th1 and Th2 lymphocytes, and modulates interferon-gamma- and interleukin-4-induced activation of human keratinocytes. J. Invest. Dermatol 2000. 115: 81-87.
-
(2000)
J. Invest. Dermatol
, vol.115
, pp. 81-87
-
-
Albanesi, C.1
Scarponi, C.S.2
Cavani, A.3
Federici, M.4
Nasorri, F.5
Girolomoni, G.6
-
24
-
-
0034161692
-
High levels of IL-17 in rheumatoid arthritis patients: IL-15 triggers in vitro IL-17 production via cyclosporin A-sensitive mechanism
-
Ziolkowska, M., Koc, A., Luszczykiewicz, G., Ksiezopolska-Pietrzak, K., Klimczak, E., Chwalinska-Sadowska, H. and Maslinski, W., High levels of IL-17 in rheumatoid arthritis patients: IL-15 triggers in vitro IL-17 production via cyclosporin A-sensitive mechanism. J. Immunol 2000. 164: 2832-2838.
-
(2000)
J. Immunol
, vol.164
, pp. 2832-2838
-
-
Ziolkowska, M.1
Koc, A.2
Luszczykiewicz, G.3
Ksiezopolska-Pietrzak, K.4
Klimczak, E.5
Chwalinska-Sadowska, H.6
Maslinski, W.7
-
25
-
-
0037442137
-
IL-17, produced by lymphocytes and neutrophils, is necessary for lipopolysaccharide-induced airway neutrophilia: IL-15 as a possible trigger
-
Ferretti, S., Bonneau, O., Dubois, G. R., Jones, C. E. and Trifilieff, A., IL-17, produced by lymphocytes and neutrophils, is necessary for lipopolysaccharide-induced airway neutrophilia: IL-15 as a possible trigger. J. Immunol 2003. 170: 2106-2112.
-
(2003)
J. Immunol
, vol.170
, pp. 2106-2112
-
-
Ferretti, S.1
Bonneau, O.2
Dubois, G.R.3
Jones, C.E.4
Trifilieff, A.5
-
26
-
-
0037218610
-
Impaired accumulation and function of memory CD4 T cells in human IL-12 receptor beta 1 deficiency
-
Cleary, A. M., Tu, W. W., Enright, A., Giffon, T., De-waal-Malefyt, R., Gutierrez, K. and Lewis, D. B., Impaired accumulation and function of memory CD4 T cells in human IL-12 receptor beta 1 deficiency. J. Immunol 2003. 170: 597-603.
-
(2003)
J. Immunol
, vol.170
, pp. 597-603
-
-
Cleary, A.M.1
Tu, W.W.2
Enright, A.3
Giffon, T.4
De-waal-Malefyt, R.5
Gutierrez, K.6
Lewis, D.B.7
-
27
-
-
0033134608
-
IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis
-
Kotake, S., Udagawa, N., Takahashi, N., Matsuzaki, K., Itoh, K., Ishiyama, S., Saito, S. et al., IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis. J. Ciin. Invest 1999. 103:1345-1352.
-
(1999)
J. Ciin. Invest
, vol.103
, pp. 1345-1352
-
-
Kotake, S.1
Udagawa, N.2
Takahashi, N.3
Matsuzaki, K.4
Itoh, K.5
Ishiyama, S.6
Saito, S.7
-
28
-
-
0344585384
-
Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice
-
Nakae, S., Nambu, A., Sudo, K. and Iwakura, Y., Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice. J. Immunol 2003. 171: 6173-6177.
-
(2003)
J. Immunol
, vol.171
, pp. 6173-6177
-
-
Nakae, S.1
Nambu, A.2
Sudo, K.3
Iwakura, Y.4
-
29
-
-
0033758344
-
Increased interleukin-17 production in patients with systemic sclerosis
-
Kurasawa, K., Hirose, K., Sano, H., Endo, H., Shinkai, H., Nawata, Y., Takabayashi, K. et al., Increased interleukin-17 production in patients with systemic sclerosis. Arthritis Rheum 2000. 43: 2455-2463.
-
(2000)
Arthritis Rheum
, vol.43
, pp. 2455-2463
-
-
Kurasawa, K.1
Hirose, K.2
Sano, H.3
Endo, H.4
Shinkai, H.5
Nawata, Y.6
Takabayashi, K.7
-
30
-
-
0036105484
-
Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis
-
Lock, C., Hermans, G., Pedotti, R., Brendolan, A., Schadt, E., Garren, H., Langer-Gould, A. et al., Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis. Nat. Med. 2002. 8: 500-508.
-
(2002)
Nat. Med.
, vol.8
, pp. 500-508
-
-
Lock, C.1
Hermans, G.2
Pedotti, R.3
Brendolan, A.4
Schadt, E.5
Garren, H.6
Langer-Gould, A.7
-
32
-
-
27544465354
-
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
-
Park, H., Li, Z., Yang, X. O., Chang, S. H., Nurieva, R., Wang, Y. H., Wang, Y. et al., A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat. Immunol. 2005. 6: 1133-1141.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 1133-1141
-
-
Park, H.1
Li, Z.2
Yang, X.O.3
Chang, S.H.4
Nurieva, R.5
Wang, Y.H.6
Wang, Y.7
-
33
-
-
13244283212
-
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
-
Langrish, C. L., Chen, Y., Blumenschein, W. M., Mattson, J., Basham, B., Sedgwick, J. D., McClanahan, T. et al., IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J. Exp. Med. 2005. 201: 233-240.
-
(2005)
J. Exp. Med.
, vol.201
, pp. 233-240
-
-
Langrish, C.L.1
Chen, Y.2
Blumenschein, W.M.3
Mattson, J.4
Basham, B.5
Sedgwick, J.D.6
McClanahan, T.7
-
34
-
-
33644957200
-
Understanding the IL-23-IL-17 immune pathway
-
in press
-
McKenzie, B. S., Kastelein, R. A., Daniel, J. and Cua, D. J., Understanding the IL-23-IL-17 immune pathway. Trends Immunol. 2005, in press.
-
(2005)
Trends Immunol.
-
-
McKenzie, B.S.1
Kastelein, R.A.2
Daniel, J.3
Cua, D.J.4
-
35
-
-
27544469550
-
T(H)-17: A giant step from T(H)1 and T(H)2
-
Wynn, T. A., T(H)-17: a giant step from T(H)1 and T(H)2. Nat. Immunol. 2005. 6: 1069-1070.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 1069-1070
-
-
Wynn, T.A.1
-
36
-
-
2942720565
-
Commensal Gram-negative bacteria prime human dendritic cells for enhanced IL-23 and IL-27 expression and enhanced Th1 development
-
Smits, H. H., van Beelen, A. J., Hessle, C., Westland, R., de Jong, E., Soeteman, E., Wold, A. et al., Commensal Gram-negative bacteria prime human dendritic cells for enhanced IL-23 and IL-27 expression and enhanced Th1 development. Eur. J. Immunol 2004. 34: 1371-80.
-
(2004)
Eur. J. Immunol
, vol.34
, pp. 1371-1380
-
-
Smits, H.H.1
van Beelen, A.J.2
Hessle, C.3
Westland, R.4
de Jong, E.5
Soeteman, E.6
Wold, A.7
-
37
-
-
13544251389
-
Extracellular nucleotide signaling by P2 receptors inhibits IL-12 and enhances IL-23 expression in human dendritic cells: A novel role for the cAMP pathway
-
Schnurr, M., Toy, T., Shin, A., Wagner, M., Cebon, J. and Maraskovsky, E., Extracellular nucleotide signaling by P2 receptors inhibits IL-12 and enhances IL-23 expression in human dendritic cells: a novel role for the cAMP pathway. Blood 2005. 105: 1582-1589.
-
(2005)
Blood
, vol.105
, pp. 1582-1589
-
-
Schnurr, M.1
Toy, T.2
Shin, A.3
Wagner, M.4
Cebon, J.5
Maraskovsky, E.6
-
38
-
-
0030785504
-
Biological properties and therapeutic applications of interleukin-12
-
Trinchieri, G., Biological properties and therapeutic applications of interleukin-12. Eur. Cytokine Netw 1997. 8: 305-307.
-
(1997)
Eur. Cytokine Netw
, vol.8
, pp. 305-307
-
-
Trinchieri, G.1
|