-
1
-
-
0030805622
-
A generalised increase in protein carbonyls in the brain in Parkinson's but not incidental Lewy body disease
-
Alam, Z.I., Daniel, S.E., Lees, A.J., Marsden, C.D., Jenner, P. & Halliwell, B. (1997a) A generalised increase in protein carbonyls in the brain in Parkinson's but not incidental Lewy body disease. J. Neurochem., 69, 1326-1329.
-
(1997)
J. Neurochem.
, vol.69
, pp. 1326-1329
-
-
Alam, Z.I.1
Daniel, S.E.2
Lees, A.J.3
Marsden, C.D.4
Jenner, P.5
Halliwell, B.6
-
2
-
-
0030878073
-
Oxidative DNA damage in the parkinsonian brain: An apparent selective increase in 8-hydroxyguanine levels in substantia nigra
-
Alam, Z.I., Jenner, A., Daniel, S.E., Lees, A.J., Cairns, N., Marsden, C.D., Jenner, P. & Halliwell, B. (1997b) Oxidative DNA damage in the parkinsonian brain: an apparent selective increase in 8-hydroxyguanine levels in substantia nigra. J. Neurochem., 69, 1196-1203.
-
(1997)
J. Neurochem.
, vol.69
, pp. 1196-1203
-
-
Alam, Z.I.1
Jenner, A.2
Daniel, S.E.3
Lees, A.J.4
Cairns, N.5
Marsden, C.D.6
Jenner, P.7
Halliwell, B.8
-
3
-
-
0034520369
-
The molecular mechanism of dopamine-induced apoptosis: Identification and characterization of genes that mediate dopamine toxicity
-
Barzilai, A., Zilkha-Falb, R., Daily, D., Stern, N., Offen, D., Ziv, I., Melamed, E. & Shirvan, A. (2000) The molecular mechanism of dopamine-induced apoptosis: identification and characterization of genes that mediate dopamine toxicity. J. Neural Transm., 60 (Suppl.), 59-76.
-
(2000)
J. Neural Transm.
, vol.60
, Issue.SUPPL.
, pp. 59-76
-
-
Barzilai, A.1
Zilkha-Falb, R.2
Daily, D.3
Stern, N.4
Offen, D.5
Ziv, I.6
Melamed, E.7
Shirvan, A.8
-
4
-
-
0037378758
-
Activation of proapoptotic cascade by dopamine in renal epithelial cells is fully dependent on hydrogen peroxide generation by monoamine oxidases
-
Bianchi, P., Seguelas, M.H., Parini, A. & Cambon, C. (2003) Activation of proapoptotic cascade by dopamine in renal epithelial cells is fully dependent on hydrogen peroxide generation by monoamine oxidases. J. Am. Soc. Nephrol., 14, 855-862.
-
(2003)
J. Am. Soc. Nephrol.
, vol.14
, pp. 855-862
-
-
Bianchi, P.1
Seguelas, M.H.2
Parini, A.3
Cambon, C.4
-
5
-
-
0028364696
-
Immunocytochemical analysis of tumor necrosis factor and its receptors in Parkinson's disease
-
Boka, G., Anglade, P., Wallach, D., Javoy-Agid, F., Agid, Y. & Hirsch, E.C. (1994) Immunocytochemical analysis of tumor necrosis factor and its receptors in Parkinson's disease. Neurosci. Lett., 172, 151-154.
-
(1994)
Neurosci. Lett.
, vol.172
, pp. 151-154
-
-
Boka, G.1
Anglade, P.2
Wallach, D.3
Javoy-Agid, F.4
Agid, Y.5
Hirsch, E.C.6
-
6
-
-
0028952832
-
Effect of peroxynitrite on the mitochondrial respiratory chain: Differential susceptibility of neurones and astrocytes in primary culture
-
Bolaños, J.P., Heales, S.J.R., Land, J.M. & Clark, J.B. (1995) Effect of peroxynitrite on the mitochondrial respiratory chain: differential susceptibility of neurones and astrocytes in primary culture. J. Neurochem., 64, 1965-1972.
-
(1995)
J. Neurochem.
, vol.64
, pp. 1965-1972
-
-
Bolaños, J.P.1
Heales, S.J.R.2
Land, J.M.3
Clark, J.B.4
-
7
-
-
0028948393
-
Exposure to low concentrations of hydrogen peroxide causes delayed endothelial cell death and inhibits proliferation of surviving cells
-
de Bono, D.P. & Yang, W.D. (1995) Exposure to low concentrations of hydrogen peroxide causes delayed endothelial cell death and inhibits proliferation of surviving cells. Atherosclerosis, 114, 235-245.
-
(1995)
Atherosclerosis
, vol.114
, pp. 235-245
-
-
De Bono, D.P.1
Yang, W.D.2
-
8
-
-
0035162338
-
Mitochondria deficient in complex I activity are depolarized by hydrogen peroxide in nerve terminals: Relevance to Parkinson's disease
-
Chinopoulos, C. & Adam-Vizi, V. (2001) Mitochondria deficient in complex I activity are depolarized by hydrogen peroxide in nerve terminals: relevance to Parkinson's disease. J. Neurochem., 76, 302-306.
-
(2001)
J. Neurochem.
, vol.76
, pp. 302-306
-
-
Chinopoulos, C.1
Adam-Vizi, V.2
-
9
-
-
0034776095
-
Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: Implications for Lewy-body formation in Parkinson disease
-
Chung, K.K., Zhang, Y., Lim, K.L., Tanaka, Y., Huang, H., Gao, J., Ross, C.A., Dawson, V.L. & Dawson, T.M. (2001) Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease. Nat. Med., 7, 1144-1150.
-
(2001)
Nat. Med.
, vol.7
, pp. 1144-1150
-
-
Chung, K.K.1
Zhang, Y.2
Lim, K.L.3
Tanaka, Y.4
Huang, H.5
Gao, J.6
Ross, C.A.7
Dawson, V.L.8
Dawson, T.M.9
-
10
-
-
0037338634
-
Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death
-
Darios, F., Corti, O., Lucking, C.B., Hampe, C., Muriel, M.P., Abbas, N., Gu, W.J., Hirsch, E.C., Rooney, T., Ruberg, M. & Brice, A. (2003) Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria- dependent cell death. Hum. Mol. Genet., 12, 517-526.
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 517-526
-
-
Darios, F.1
Corti, O.2
Lucking, C.B.3
Hampe, C.4
Muriel, M.P.5
Abbas, N.6
Gu, W.J.7
Hirsch, E.C.8
Rooney, T.9
Ruberg, M.10
Brice, A.11
-
11
-
-
0141741347
-
Parkinson's disease: Mechanisms and models
-
Dauer, W. & Przedborski, S. (2003) Parkinson's disease: mechanisms and models. Neuron, 39, 889-909.
-
(2003)
Neuron
, vol.39
, pp. 889-909
-
-
Dauer, W.1
Przedborski, S.2
-
12
-
-
0024585155
-
Basal lipid peroxidation in substantia nigra is increased in Parkinson's disease
-
Dexter, D.T., Carter, C.J., Wells, F.R., Javoy-Agid, F., Agid, Y., Lees, A., Jenner, P. & Marsden, C.D. (1989) Basal lipid peroxidation in substantia nigra is increased in Parkinson's disease. J. Neurochem., 52, 381-389.
-
(1989)
J. Neurochem.
, vol.52
, pp. 381-389
-
-
Dexter, D.T.1
Carter, C.J.2
Wells, F.R.3
Javoy-Agid, F.4
Agid, Y.5
Lees, A.6
Jenner, P.7
Marsden, C.D.8
-
13
-
-
0033899176
-
Glutathione metabolism in brain metabolic interaction between astrocytes and neurons in the defense against reactive oxygen species
-
Dringen, R., Gutterer, J.M. & Hirrlinger, J. (2000) Glutathione metabolism in brain metabolic interaction between astrocytes and neurons in the defense against reactive oxygen species. Eur. J. Biochem., 267, 4912-4916.
-
(2000)
Eur. J. Biochem.
, vol.267
, pp. 4912-4916
-
-
Dringen, R.1
Gutterer, J.M.2
Hirrlinger, J.3
-
14
-
-
0038727936
-
Description of Parkinson's disease as a clinical syndrome
-
Fahn, S. (2003) Description of Parkinson's disease as a clinical syndrome. Ann. NY Acad. Sci., 991, 1-14.
-
(2003)
Ann. NY Acad. Sci.
, vol.991
, pp. 1-14
-
-
Fahn, S.1
-
15
-
-
0026484388
-
The oxidant stress hypothesis in Parkinson's disease: Evidence supporting it
-
Fahn, S. & Cohen, G. (1992) The oxidant stress hypothesis in Parkinson's disease: evidence supporting it. Ann. Neurol., 32, 804-812.
-
(1992)
Ann. Neurol.
, vol.32
, pp. 804-812
-
-
Fahn, S.1
Cohen, G.2
-
16
-
-
0038308447
-
Differential effect of nitric oxide on glutathione metabolism and mitochondrial function in astrocytes and neurones: Implications for neuroprotection/neurodegeneration?
-
Gegg, M.E., Beltran, B., Salas-Pino, S., Bolanos, J.P., Clark, J.B., Moncada, S. & Heales, S.J. (2003) Differential effect of nitric oxide on glutathione metabolism and mitochondrial function in astrocytes and neurones: implications for neuroprotection/neurodegeneration? J. Neurochem., 86, 228-237.
-
(2003)
J. Neurochem.
, vol.86
, pp. 228-237
-
-
Gegg, M.E.1
Beltran, B.2
Salas-Pino, S.3
Bolanos, J.P.4
Clark, J.B.5
Moncada, S.6
Heales, S.J.7
-
17
-
-
0141891953
-
Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons
-
Goldberg, M.S., Fleming, S.M., Palacino, J.J., Cepada, C., Lam, H.A., Bhatnagar, A., Meloni, E.G., Wu, N., Ackerson, L.C., Klapstein, G.J., Gajendiran, M., Roth, B.L., Chesselet, M.F., Maidment, N.T., Levine, M.S. & Shen, J. (2003) Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons. J. Biol. Chem., 278, 43628-43635.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 43628-43635
-
-
Goldberg, M.S.1
Fleming, S.M.2
Palacino, J.J.3
Cepada, C.4
Lam, H.A.5
Bhatnagar, A.6
Meloni, E.G.7
Wu, N.8
Ackerson, L.C.9
Klapstein, G.J.10
Gajendiran, M.11
Roth, B.L.12
Chesselet, M.F.13
Maidment, N.T.14
Levine, M.S.15
Shen, J.16
-
18
-
-
4944245967
-
Oxidative damage and cell cycle activation in Drosophila Parkin mutants
-
Greene, J.C., Whitworth, A.J., Leither, J.L., Andrews, L.A. & Pallank, L.J. (2003) Oxidative damage and cell cycle activation in Drosophila Parkin mutants. Soc. Neurosci. Abstr., 29, 132.7.
-
(2003)
Soc. Neurosci. Abstr.
, vol.29
-
-
Greene, J.C.1
Whitworth, A.J.2
Leither, J.L.3
Andrews, L.A.4
Pallank, L.J.5
-
19
-
-
17344374068
-
Lipid-mediated enhancement of transfection by a nonviral integrin-targeting vector
-
Hart, S.L., Arancibia-Carcamo, C.V., Wolfert, M.A., Mailhos, C., O'Reilly, N.J., Ali, R.R., Coutelle, C., George, A.J., Harbottle, R.P., Knight, A.M., Larkin, D.F., Levinsky, R.J., Seymour, L.W., Thrasher, A.J. & Kinnon, C. (1998) Lipid-mediated enhancement of transfection by a nonviral integrin-targeting vector. Hum. Gene Ther., 9, 575-585.
-
(1998)
Hum. Gene Ther.
, vol.9
, pp. 575-585
-
-
Hart, S.L.1
Arancibia-Carcamo, C.V.2
Wolfert, M.A.3
Mailhos, C.4
O'Reilly, N.J.5
Ali, R.R.6
Coutelle, C.7
George, A.J.8
Harbottle, R.P.9
Knight, A.M.10
Larkin, D.F.11
Levinsky, R.J.12
Seymour, L.W.13
Thrasher, A.J.14
Kinnon, C.15
-
20
-
-
12944250987
-
Caspase-3: A vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson's disease
-
Hartmann, A., Hunot, S., Michel, P.P., Muriel, M.P., Vyas, S., Faucheux, B.A., Mouatt-Prigent, A., Tunnel, H., Srinivasan, A., Ruberg, M., Evan, G.I., Agid, Y. & Hirsch, E.C. (2000) Caspase-3: a vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson's disease. Proc. Natl Acad. Sci. USA, 97, 2875-2880.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 2875-2880
-
-
Hartmann, A.1
Hunot, S.2
Michel, P.P.3
Muriel, M.P.4
Vyas, S.5
Faucheux, B.A.6
Mouatt-Prigent, A.7
Tunnel, H.8
Srinivasan, A.9
Ruberg, M.10
Evan, G.I.11
Agid, Y.12
Hirsch, E.C.13
-
21
-
-
0035313071
-
Caspase-8 is an effector in apoptotic death of dopaminergic neurons in Parkinson's disease, but pathway inhibition results in neuronal necrosis
-
Hartmann, A., Troadec, J.D., Hunot, S., Kikly, K., Faucheux, B.A., Mouatt-Prigent, A., Ruberg, M., Agid, Y. & Hirsch, E.C. (2001) Caspase-8 is an effector in apoptotic death of dopaminergic neurons in Parkinson's disease, but pathway inhibition results in neuronal necrosis. J. Neurosci., 21, 2247-2255.
-
(2001)
J. Neurosci.
, vol.21
, pp. 2247-2255
-
-
Hartmann, A.1
Troadec, J.D.2
Hunot, S.3
Kikly, K.4
Faucheux, B.A.5
Mouatt-Prigent, A.6
Ruberg, M.7
Agid, Y.8
Hirsch, E.C.9
-
22
-
-
0031715925
-
Glial cells and inflammation in Parkinson's disease: A role in neurodegeneration?
-
Hirsch, B.C., Hunot, S., Damier, P. & Faucheux, B. (1998) Glial cells and inflammation in Parkinson's disease: a role in neurodegeneration? Ann. Neurol., 44, S115-S120.
-
(1998)
Ann. Neurol.
, vol.44
-
-
Hirsch, B.C.1
Hunot, S.2
Damier, P.3
Faucheux, B.4
-
23
-
-
0033407094
-
Dopaminergic neurons degenerate by apoptosis in Parkinson's disease
-
Hirsch, E.C., Hunot, S., Faucheux, B., Agid, Y., Mizuno, Y., Mochizuki, H., Tatton, W.G., Tatton, N. & Olanow, W.C. (1999) Dopaminergic neurons degenerate by apoptosis in Parkinson's disease. Mov. Disord., 14, 383-385.
-
(1999)
Mov. Disord.
, vol.14
, pp. 383-385
-
-
Hirsch, E.C.1
Hunot, S.2
Faucheux, B.3
Agid, Y.4
Mizuno, Y.5
Mochizuki, H.6
Tatton, W.G.7
Tatton, N.8
Olanow, W.C.9
-
24
-
-
0035967883
-
An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin
-
Imai, Y., Soda, M., Inoue, H., Hattori, N., Mizuno, Y. & Takahashi, R. (2001) An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin. Cell, 105, 891-902.
-
(2001)
Cell
, vol.105
, pp. 891-902
-
-
Imai, Y.1
Soda, M.2
Inoue, H.3
Hattori, N.4
Mizuno, Y.5
Takahashi, R.6
-
25
-
-
0034680913
-
Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity
-
Imai, Y., Soda, M. & Takahashi, R. (2000) Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity. J. Biol. Chem., 275, 35661-35664.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 35661-35664
-
-
Imai, Y.1
Soda, M.2
Takahashi, R.3
-
26
-
-
10744221310
-
Parkin gene inactivation alters behaviour and dopamine neurotransmission in the mouse
-
Itier, J.-M., Ibanez, P., Mena, M.A., Abbas, N., Cohen-Salmon, C., Bohme, G.A., Laville, M., Pratt, J., Corti, O., Pradier, L., Ret, G., Joubert, C., Periquet, M., Araujo, F., Negroni, J., Casarejos, M.J., Canals, S., Solano, R., Serrano, A., Gallego, E., Sanchez, M., Denefle, P., Benavides, J., Tremp, G., Rooney, T.A., Brice, A. & Garcia de Febenes, S. (2003) Parkin gene inactivation alters behaviour and dopamine neurotransmission in the mouse. Hum. Mol. Genet., 12, 2277-2291.
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 2277-2291
-
-
Itier, J.-M.1
Ibanez, P.2
Mena, M.A.3
Abbas, N.4
Cohen-Salmon, C.5
Bohme, G.A.6
Laville, M.7
Pratt, J.8
Corti, O.9
Pradier, L.10
Ret, G.11
Joubert, C.12
Periquet, M.13
Araujo, F.14
Negroni, J.15
Casarejos, M.J.16
Canals, S.17
Solano, R.18
Serrano, A.19
Gallego, E.20
Sanchez, M.21
Denefle, P.22
Benavides, J.23
Tremp, G.24
Rooney, T.A.25
Brice, A.26
Garcia De Febenes, S.27
more..
-
27
-
-
0026635461
-
Oxidative stress as a cause of nigral cell death in Parkinson's disease and incidental Lewy body disease
-
The Royal Kings and Queens Parkinson's Disease Research Group
-
Jenner, P., Dexter, D.T., Sian, J., Schapira, A.M. & Marsden, C.D. (1992) Oxidative stress as a cause of nigral cell death in Parkinson's disease and incidental Lewy body disease. The Royal Kings and Queens Parkinson's Disease Research Group. Ann. Neurol., 32 (Suppl.), S82-S87.
-
(1992)
Ann. Neurol.
, vol.32
, Issue.SUPPL.
-
-
Jenner, P.1
Dexter, D.T.2
Sian, J.3
Schapira, A.M.4
Marsden, C.D.5
-
28
-
-
0031687793
-
Understanding cell death in Parkinson's disease
-
Jenner, P. & Olanow, C.W. (1998) Understanding cell death in Parkinson's disease. Ann. Neurol., 44, S72-S84.
-
(1998)
Ann. Neurol.
, vol.44
-
-
Jenner, P.1
Olanow, C.W.2
-
29
-
-
0034025513
-
Dopamine-induced apoptosis is mediated by oxidative stress and is enhanced by cyanide in differentiated PC12 cells
-
Jones, D.C., Gunasekar, P.O., Borowitz, J.L. & Isom, G.E. (2000) Dopamine-induced apoptosis is mediated by oxidative stress and is enhanced by cyanide in differentiated PC12 cells. J. Neurochem., 74, 2296-2304.
-
(2000)
J. Neurochem.
, vol.74
, pp. 2296-2304
-
-
Jones, D.C.1
Gunasekar, P.O.2
Borowitz, J.L.3
Isom, G.E.4
-
30
-
-
0037013277
-
Caspase-mediated parkin cleavage in apoptotic cell death
-
Kahns, S., Lykkebo, S., Jakobsen, L.D., Nielsen, M.S. & Jensen, P.H. (2002) Caspase-mediated parkin cleavage in apoptotic cell death. J. Biol. Chem., 277, 15303-15308.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 15303-15308
-
-
Kahns, S.1
Lykkebo, S.2
Jakobsen, L.D.3
Nielsen, M.S.4
Jensen, P.H.5
-
31
-
-
0030933781
-
Activation of CPP32 during apoptosis of neurons and astrocytes
-
Keane, R.W., Srinivasan, A., Foster, L.M., Testa, M.P., Ord, T., Nonner, D., Wang, H.G., Reed, J.C., Bredesen, D.E. & Kayalar, C. (1997) Activation of CPP32 during apoptosis of neurons and astrocytes. J. Neurosci. Res., 48, 168-180.
-
(1997)
J. Neurosci. Res.
, vol.48
, pp. 168-180
-
-
Keane, R.W.1
Srinivasan, A.2
Foster, L.M.3
Testa, M.P.4
Ord, T.5
Nonner, D.6
Wang, H.G.7
Reed, J.C.8
Bredesen, D.E.9
Kayalar, C.10
-
32
-
-
0035503074
-
Microglial activation and dopaminergic cell injury: An in vitro model relevant to Parkinson's disease
-
Le, W., Rowe, D., Xie, W., Ortiz, I., He, Y. & Appel, S.H. (2001) Microglial activation and dopaminergic cell injury: an in vitro model relevant to Parkinson's disease. J. Neurosci., 21, 8447-8455.
-
(2001)
J. Neurosci.
, vol.21
, pp. 8447-8455
-
-
Le, W.1
Rowe, D.2
Xie, W.3
Ortiz, I.4
He, Y.5
Appel, S.H.6
-
33
-
-
0036902707
-
Astrocytic but not neuronal increased expression and redistribution of parkin during unfolded protein stress
-
Ledesma, M.D., Galvan, C., Hellias, B., Dotti, C. & Jensen, P.H. (2002) Astrocytic but not neuronal increased expression and redistribution of parkin during unfolded protein stress. J. Neurochem., 83, 1431-1440.
-
(2002)
J. Neurochem.
, vol.83
, pp. 1431-1440
-
-
Ledesma, M.D.1
Galvan, C.2
Hellias, B.3
Dotti, C.4
Jensen, P.H.5
-
34
-
-
0032249190
-
Apoptosis versus necrosis: The shape of neuronal cell death
-
Leist, M. & Nicotera, P. (1998) Apoptosis versus necrosis: the shape of neuronal cell death. Results Probl. Cell Differ., 24, 105-135.
-
(1998)
Results Probl. Cell Differ.
, vol.24
, pp. 105-135
-
-
Leist, M.1
Nicotera, P.2
-
35
-
-
0034727885
-
Staurosporine- and H-7-induced cell death in SH-SY5Y neuroblastoma cells is associated with caspase-2 and caspase-3 activation, but not with activation of the FAS/FAS-L-caspase-8 signaling pathway
-
Lopez, E. & Ferrer, I. (2000) Staurosporine- and H-7-induced cell death in SH-SY5Y neuroblastoma cells is associated with caspase-2 and caspase-3 activation, but not with activation of the FAS/FAS-L-caspase-8 signaling pathway. Brain Res. Mol. Brain Res., 85, 61-67.
-
(2000)
Brain Res. Mol. Brain Res.
, vol.85
, pp. 61-67
-
-
Lopez, E.1
Ferrer, I.2
-
36
-
-
0032488992
-
Dopamine induces apoptosis through an oxidation-involved SAPK/JNK activation pathway
-
Luo, Y., Umegaki, H., Wang, X., Abe, R. & Roth, G.S. (1998) Dopamine induces apoptosis through an oxidation-involved SAPK/JNK activation pathway. J. Biol. Chem., 273, 3756-3764.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 3756-3764
-
-
Luo, Y.1
Umegaki, H.2
Wang, X.3
Abe, R.4
Roth, G.S.5
-
37
-
-
0035985232
-
The role of astroglia on the survival of dopamine neurons
-
Mena, M.A., de Bernardo, S., Casarejos, M.J., Canals, S. & Rodriguez-Martin, E. (2002) The role of astroglia on the survival of dopamine neurons. Mol. Neurobiol., 25, 245-263.
-
(2002)
Mol. Neurobiol.
, vol.25
, pp. 245-263
-
-
Mena, M.A.1
De Bernardo, S.2
Casarejos, M.J.3
Canals, S.4
Rodriguez-Martin, E.5
-
38
-
-
0034023082
-
Caspase activities and tumor necrosis factor receptor R1 (p55) level are elevated in the substantia nigra from parkinsonian brain
-
Mogi, M., Togari, A., Kondo, T., Mizuno, Y., Komure, O., Kuno, S., Ichinose, H. & Nagatsu, T. (2000) Caspase activities and tumor necrosis factor receptor R1 (p55) level are elevated in the substantia nigra from parkinsonian brain. J. Neural Transm., 107, 335-341.
-
(2000)
J. Neural Transm.
, vol.107
, pp. 335-341
-
-
Mogi, M.1
Togari, A.2
Kondo, T.3
Mizuno, Y.4
Komure, O.5
Kuno, S.6
Ichinose, H.7
Nagatsu, T.8
-
39
-
-
0036186039
-
Involvement of caspases and calpains in cerebrocortical neuronal cell death is stimulus-dependent
-
Moore, J.D., Rothwell, N.J. & Gibson, R.M. (2002) Involvement of caspases and calpains in cerebrocortical neuronal cell death is stimulus-dependent. Br. J. Pharmacol., 135, 1069-1077.
-
(2002)
Br. J. Pharmacol.
, vol.135
, pp. 1069-1077
-
-
Moore, J.D.1
Rothwell, N.J.2
Gibson, R.M.3
-
40
-
-
0347917234
-
Parkin is recruited into aggresomes in a stress-specific manner: Over-expression of parkin reduces aggresome formation but can be dissociated from parkin's effect on neuronal survival
-
Muqit, M.M.K., Davidson, S.M., Payne Smith, M.D., MacCormac, L.P., Kahns, S., Jensen, P.H., Wood, N.W. & Latchman, D.S. (2004) Parkin is recruited into aggresomes in a stress-specific manner: over-expression of parkin reduces aggresome formation but can be dissociated from parkin's effect on neuronal survival. Hum. Mol. Genet., 13, 117-135.
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 117-135
-
-
Muqit, M.M.K.1
Davidson, S.M.2
Payne Smith, M.D.3
MacCormac, L.P.4
Kahns, S.5
Jensen, P.H.6
Wood, N.W.7
Latchman, D.S.8
-
41
-
-
0030638249
-
Neuronal necrosis and apoptosis: Two distinct events induced by exposure to glutamate or oxidative stress
-
Nicotera, P., Ankarcrona, M., Bonfoco, E., Orrenius, S. & Lipton, S.A. (1997) Neuronal necrosis and apoptosis: two distinct events induced by exposure to glutamate or oxidative stress. Adv. Neurol., 72, 95-101.
-
(1997)
Adv. Neurol.
, vol.72
, pp. 95-101
-
-
Nicotera, P.1
Ankarcrona, M.2
Bonfoco, E.3
Orrenius, S.4
Lipton, S.A.5
-
42
-
-
0033290849
-
Apoptosis and necrosis: Different execution of the same death
-
Nicotera, P., Leist, M. & Ferrando-May, E. (1999) Apoptosis and necrosis: different execution of the same death. Biochem. Soc. Symp., 66, 69-73.
-
(1999)
Biochem. Soc. Symp.
, vol.66
, pp. 69-73
-
-
Nicotera, P.1
Leist, M.2
Ferrando-May, E.3
-
43
-
-
0032936755
-
Etiology and pathogenesis of Parkinson's disease
-
Olanow, C.W. & Tatton, W.G. (1999) Etiology and pathogenesis of Parkinson's disease. Annu. Rev. Neurosci., 22, 123-144.
-
(1999)
Annu. Rev. Neurosci.
, vol.22
, pp. 123-144
-
-
Olanow, C.W.1
Tatton, W.G.2
-
44
-
-
2442481789
-
Mitochondrial dysfunction and oxidative damage in parkin-deficient mice
-
Palacino, J.J., Sagi, D., Goldberg, M.S., Krauss, S., Motz, C., Wacker, M., Klose, J. & Shen, J. (2004) Mitochondrial dysfunction and oxidative damage in parkin-deficient mice. J. Biol. Chem., 279, 18614-18622.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 18614-18622
-
-
Palacino, J.J.1
Sagi, D.2
Goldberg, M.S.3
Krauss, S.4
Motz, C.5
Wacker, M.6
Klose, J.7
Shen, J.8
-
45
-
-
0042592947
-
MDM2 promotes ubiquitination and degradation of MDMX
-
Pan, Y. & Chen, J. (2003) MDM2 promotes ubiquitination and degradation of MDMX. Mol. Cell Biol., 23, 5113-5121.
-
(2003)
Mol. Cell Biol.
, vol.23
, pp. 5113-5121
-
-
Pan, Y.1
Chen, J.2
-
46
-
-
0037137702
-
Parkin protects against the toxicity associated with mutant alpha-synuclein: Proteasome dysfunction selectively affects catecholaminergic neurons
-
Petrucelli, L., O'Farrell, C., Lockhart, P.J., Baptista, M., Kehoe, K., Vink, L., Choi, P., Wolozin, B., Farrer, M., Hardy, J. & Cookson, M.R. (2002) Parkin protects against the toxicity associated with mutant alpha-synuclein: proteasome dysfunction selectively affects catecholaminergic neurons. Neuron, 36, 1007-1019.
-
(2002)
Neuron
, vol.36
, pp. 1007-1019
-
-
Petrucelli, L.1
O'Farrell, C.2
Lockhart, P.J.3
Baptista, M.4
Kehoe, K.5
Vink, L.6
Choi, P.7
Wolozin, B.8
Farrer, M.9
Hardy, J.10
Cookson, M.R.11
-
47
-
-
0028922186
-
Apoptotic death in an in vitro model of neuronal oxidative stress
-
Ratan, R.R. & Baraban, J.M. (1995) Apoptotic death in an in vitro model of neuronal oxidative stress. Clin. Exp. Pharmacol. Physiol., 22, 309-310.
-
(1995)
Clin. Exp. Pharmacol. Physiol.
, vol.22
, pp. 309-310
-
-
Ratan, R.R.1
Baraban, J.M.2
-
48
-
-
0030779147
-
Neuronal cell death: When, why and how
-
Rubin, L.L. (1997) Neuronal cell death: when, why and how. Br. Med., 53, 617-631.
-
(1997)
Br. Med.
, vol.53
, pp. 617-631
-
-
Rubin, L.L.1
-
49
-
-
0033899208
-
Glutathione, oxidative stress and neurodegeneration
-
Schulz, J.B., Lindenau, J., Seyfried, J. & Dichgans, J. (2000) Glutathione, oxidative stress and neurodegeneration. Eur. J. Biochem., 267, 4904-4911.
-
(2000)
Eur. J. Biochem.
, vol.267
, pp. 4904-4911
-
-
Schulz, J.B.1
Lindenau, J.2
Seyfried, J.3
Dichgans, J.4
-
50
-
-
0033933048
-
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
-
Shimura, H., Hattori, N., Kubo, S., Mizuno, Y., Asakawa, S., Minoshima, S., Shimizu, N., Iwai, K., Chiba, T., Tanaka, K. & Suzuki, T. (2000) Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase. Nat. Genet., 25, 302-305.
-
(2000)
Nat. Genet.
, vol.25
, pp. 302-305
-
-
Shimura, H.1
Hattori, N.2
Kubo, S.3
Mizuno, Y.4
Asakawa, S.5
Minoshima, S.6
Shimizu, N.7
Iwai, K.8
Chiba, T.9
Tanaka, K.10
Suzuki, T.11
-
51
-
-
0035854437
-
Ubiquitination of a new form of alpha-synuclein by parkin from human brain: Implications for Parkinson's disease
-
Shimura, H., Schlossmacher, M.G., Hattori, N., Frosch, M.P., Trockenbacher, A., Schneider, R., Mizuno, Y., Kosik, K.S. & Selkoe, D.J. (2001) Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease. Science, 293, 263-269.
-
(2001)
Science
, vol.293
, pp. 263-269
-
-
Shimura, H.1
Schlossmacher, M.G.2
Hattori, N.3
Frosch, M.P.4
Trockenbacher, A.5
Schneider, R.6
Mizuno, Y.7
Kosik, K.S.8
Selkoe, D.J.9
-
52
-
-
0037422010
-
Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity
-
Staropoli, J.F., McDermott, C., Martinat, C., Schulman, B., Demireva, E. & Abeliovich, A. (2003) Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity. Neuron, 37, 735-749.
-
(2003)
Neuron
, vol.37
, pp. 735-749
-
-
Staropoli, J.F.1
McDermott, C.2
Martinat, C.3
Schulman, B.4
Demireva, E.5
Abeliovich, A.6
-
53
-
-
1942520401
-
Astrocyte apoptosis: Implications for neuroprotection
-
Takuma, K., Baba, A. & Matsuda, T. (2004) Astrocyte apoptosis: implications for neuroprotection. Prog. Neurobiol., 72, 111-127.
-
(2004)
Prog. Neurobiol.
, vol.72
, pp. 111-127
-
-
Takuma, K.1
Baba, A.2
Matsuda, T.3
-
54
-
-
0034808577
-
Parkin is linked to the ubiquitin pathway
-
Tanaka, K., Suzuki, T., Chiba, T., Shimura, H., Hattori, N. & Mizuno, Y. (2001) Parkin is linked to the ubiquitin pathway. J. Mol. Med., 79, 482-494.
-
(2001)
J. Mol. Med.
, vol.79
, pp. 482-494
-
-
Tanaka, K.1
Suzuki, T.2
Chiba, T.3
Shimura, H.4
Hattori, N.5
Mizuno, Y.6
-
55
-
-
2442668926
-
Hereditary early onset Parkinson's disease is caused by mutations in PINK1
-
doi:10.1126/science.1096284
-
Valente, E.M., Abou-Sleiman, P.M., Caputo, V., Muqit, M.M.K., Harvey, K., Gispert, S., Ali, Z., Del Turco, D., Bentivoglio, A.R., Healy, D.G., Albanese, A., Nussbaum, R., González-Maldonado, R., Deller, T., Salvil, S., Cortelli, P., Gilks, W.P., Latchman, D.S., Harvey, R.J., Dallapiccola, B., Auburger, G. & Wood, N.W. (2004) Hereditary early onset Parkinson's disease is caused by mutations in PINK1. Science, 304, 1158-1160. doi:10.1126/science. 1096284.
-
(2004)
Science
, vol.304
, pp. 1158-1160
-
-
Valente, E.M.1
Abou-Sleiman, P.M.2
Caputo, V.3
Muqit, M.M.K.4
Harvey, K.5
Gispert, S.6
Ali, Z.7
Del Turco, D.8
Bentivoglio, A.R.9
Healy, D.G.10
Albanese, A.11
Nussbaum, R.12
González-Maldonado, R.13
Deller, T.14
Salvil, S.15
Cortelli, P.16
Gilks, W.P.17
Latchman, D.S.18
Harvey, R.J.19
Dallapiccola, B.20
Auburger, G.21
Wood, N.W.22
more..
-
56
-
-
0035107766
-
Evidence for non-oxidative dopamine cytotoxicity: Potent activation of NF-kappa B and lack of protection by anti-oxidants
-
Weingarten, P., Bermak, J. & Zhou, Q.Y. (2001) Evidence for non-oxidative dopamine cytotoxicity: potent activation of NF-kappa B and lack of protection by anti-oxidants. J. Neurochem., 76, 1794-1804.
-
(2001)
J. Neurochem.
, vol.76
, pp. 1794-1804
-
-
Weingarten, P.1
Bermak, J.2
Zhou, Q.Y.3
-
57
-
-
0035017743
-
Protection of intracellular dopamine cytotoxicity by dopamine disposition and metabolism factors
-
Weingarten, P. & Zhou, Q.Y. (2001) Protection of intracellular dopamine cytotoxicity by dopamine disposition and metabolism factors. J. Neurochem., 77, 776-785.
-
(2001)
J. Neurochem.
, vol.77
, pp. 776-785
-
-
Weingarten, P.1
Zhou, Q.Y.2
-
58
-
-
0037468831
-
Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila
-
Yang, Y., Nishimura, I., Imai, Y., Takahashi, R. & Lu, B. (2003) Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila. Neuron, 37, 911-924.
-
(2003)
Neuron
, vol.37
, pp. 911-924
-
-
Yang, Y.1
Nishimura, I.2
Imai, Y.3
Takahashi, R.4
Lu, B.5
-
59
-
-
0034700158
-
Parkin functions as an E2-dependent ubiquitin-protein ligase and promotes the degradation of the synaptic vesicle-associated protein CDCrel-1
-
Zhang, Y., Gao, J., Chung, K.K., Huang, H., Dawson, V.L. & Dawson, T.M. (2000) Parkin functions as an E2-dependent ubiquitin-protein ligase and promotes the degradation of the synaptic vesicle-associated protein CDCrel-1. Proc. Natl Acad. Sci. USA, 97, 13354-13359.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 13354-13359
-
-
Zhang, Y.1
Gao, J.2
Chung, K.K.3
Huang, H.4
Dawson, V.L.5
Dawson, T.M.6
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