Spinal nerve ligation-induced activation of nuclear factor kappaB is facilitated by prostaglandins in the affected spinal cord and is a critical step in the development of mechanical allodynia

Neuroscience

Volumn 155, Issue 3, 2008, Pages 902-913

  O'Rielly, D D ^a   Loomis, C W ^a  

^a MEMORIAL UNIVERSITY OF NEWFOUNDLAND   (Canada)

Author keywords

allodynia; cyclooxygenase; NF B; spinal hyperexcitability; spinal nerve ligation; spinal prostaglandins

Indexed keywords

CYCLOOXYGENASE 2; IBUPROFEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROSTAGLANDIN DERIVATIVE; PYRROLIDINE DITHIOCARBAMATE;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CATHETERIZATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; ELECTROMYOGRAPHY; EVOKED RESPONSE; EXCITABILITY; FLEXOR REFLEX; IMMUNOBLOTTING; MALE; NERVE LIGATION; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SHAM PROCEDURE; SPINAL CORD DORSAL HORN; SPINAL NERVE; SPINAL ROOT;

ANALYSIS OF VARIANCE; ANIMALS; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, RADIATION; ELECTRIC STIMULATION; ELECTROMYOGRAPHY; FUNCTIONAL LATERALITY; HYPERALGESIA; IBUPROFEN; LIGATION; MALE; NF-KAPPA B; PAIN MEASUREMENT; PAIN THRESHOLD; PROSTAGLANDINS; RATS; RATS, SPRAGUE-DAWLEY; REFLEX; SPINAL CORD; SPINAL NERVES; TIME FACTORS;

EID: 49249098869     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2008.04.077     Document Type: Article

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