Rho-kinase mediates spinal nitric oxide formation by prostaglandin E 2 via EP3 subtype

Biochemical and Biophysical Research Communications

Volumn 338, Issue 1, 2005, Pages 550-557

  Matsumura, Shinji ^a   Abe, Tetsuya ^a   Mabuchi, Tamaki ^a   Katano, Tayo ^a   Takagi, Kunio ^a   Okuda Ashitaka, Emiko ^a   Tatsumi, Shinichi ^b   Nakai, Yoshihide ^a   Hidaka, Hiroyoshi ^c   Suzuki, Masaaki ^d   Sasaki, Yasuharu ^e   Minami, Toshiaki ^b   Ito, Seiji ^a  

^a KANSAI MEDICAL UNIVERSITY   (Japan)

^b OSAKA MEDICAL COLLEGE   (Japan)

^c D Western Therapeutics Institute   (Japan)

^d GIFU UNIVERSITY   (Japan)

^e KITASATO UNIVERSITY   (Japan)

Author keywords

EP1; EP3; Myristoylated alanine rich C kinase substrate; Neuropathic pain; Nitric oxide; Prostaglandin E2; Rho kinase; Spinal cord

Indexed keywords

2 [1 (3 AMIDINOTHIOPROPYL) 1H INDOL 3 YL] 3 (1 METHYL 1H INDOL 3 YL)MALEIMIDE; DIZOCILPINE; H 1152; INDOMETACIN; MARCKS PROTEIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN E1 RECEPTOR; PROSTAGLANDIN E2; PROSTAGLANDIN E3 RECEPTOR; PROSTAGLANDIN E4 RECEPTOR; PROSTAGLANDIN RECEPTOR STIMULATING AGENT; PROSTAGLANDIN SYNTHASE; RECEPTOR SUBTYPE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE; RHO KINASE; RHO KINASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME PHOSPHORYLATION; EXAMINATION; MOUSE; NEUROPATHIC PAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SPINAL CORD;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; DINOPROSTONE; INDOMETHACIN; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; NITRIC OXIDE; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, PROSTAGLANDIN E; SPINAL CORD;

ANIMALIA;

EID: 27544458201     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.09.058     Document Type: Article

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