Synergistic premalignant effects of chronic ethanol exposure and insulin receptor substrate-1 overexpression in liver

Hepatology Research

Volumn 38, Issue 9, 2008, Pages 940-953

  Longato, Lisa ^a   De La Monte, Suzanne ^a   Califano, Sophia ^a   Wands, Jack R ^a,b  

^a Liver Research Center Brown University Medical School   (United States)

^b RHODE ISLAND HOSPITAL   (United States)

Author keywords

Ethanol; Frizzled; Hepatocellular carcinoma; Insulin receptor substrate; Transgenic mice; WNT

Indexed keywords

ALCOHOL; ASPARTYLASPARAGINYL BETA HYDROXYLASE; CYCLINE; DNA; FRIZZLED 3 PROTEIN; FRIZZLED 7 PROTEIN; FRIZZLED PROTEIN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; INSULIN RECEPTOR SUBSTRATE 4; INTERLEUKIN 1BETA; INTERLEUKIN 6; OXYGENASE; RECEPTOR PROTEIN; RNA 18S; SOMATOMEDIN; SOMATOMEDIN B; SOMATOMEDIN B RECEPTOR; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; WNT PROTEIN; WNT1 PROTEIN; WNT3 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CHRONIC INFLAMMATION; CONTROLLED STUDY; DNA SYNTHESIS; FATTY LIVER; GENE OVEREXPRESSION; HISTOPATHOLOGY; INFLAMMATION; LIVER CELL CARCINOMA; LONG TERM EXPOSURE; MALE; MALIGNANT TRANSFORMATION; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRECANCER; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; WILD TYPE;

EID: 48949090759     PISSN: 13866346     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1872-034X.2008.00336.x     Document Type: Article

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