A carboxy-terminal truncated insulin receptor substrate-1 dominant negative protein reverses the human hepatocellular carcinoma malignant phenotype

Journal of Clinical Investigation

Volumn 98, Issue 9, 1996, Pages 2100-2108

  Tanaka, Shinji ^a   Wands, Jack R ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL CANCER CENTER   (United States)

Author keywords

carcinogenesis; human hepatoma; signal transduction

Indexed keywords

INSULIN; INSULIN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; MUTANT PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN TYROSINE KINASE; SOMATOMEDIN C;

ANCHORAGE INDEPENDENT GROWTH; ANIMAL EXPERIMENT; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CARBOXY TERMINAL SEQUENCE; CARCINOGENESIS; CELL STRUCTURE; CELL TRANSFORMATION; CONTROLLED STUDY; DELETION MUTANT; DNA TRANSFECTION; ENZYME ASSAY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; LIVER CELL CARCINOMA; MITOGENESIS; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

EID: 0029998031     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119016     Document Type: Article

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