Biochemical mechanism of modulation of human P-glycoprotein (ABCB1) by curcumin I, II, and III purified from Turmeric powder

Biochemical Pharmacology

Volumn 68, Issue 10, 2004, Pages 2043-2052

  Chearwae, W ^a,b   Anuchapreeda, S ^c   Nandigama, K ^b   Ambudkar, S V ^b   Limtrakul, P ^a  

^a Faculty of Medicine Chiang Mai University   (Thailand)

^b NATIONAL CANCER INSTITUTE   (United States)

^c CHIANG MAI UNIVERSITY   (Thailand)

Author keywords

ABC transporter; ATP hydrolysis; Chemosensitizers; Curcumin; Multidrug resistance; P glycoprotein

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; ANTIINFECTIVE AGENT; CALCEIN; CURCUMIN; CURCUMIN 1; CURCUMIN 2; CURCUMIN 3; GLYCOPROTEIN P; IODINE 125; MULTIDRUG RESISTANCE PROTEIN; RHODAMINE 123; UNCLASSIFIED DRUG; VERAPAMIL; VINBLASTINE;

ARTICLE; CANCER CELL; CARCINOMA CELL; CELL LINE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CURCUMA LONGA; CYTOTOXICITY; DOSE RESPONSE; DRUG RESISTANCE; ENZYME ACTIVITY; FREQUENCY MODULATOR; HUMAN; HUMAN CELL; IC 50; MODULATION; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; UTERINE CERVIX CARCINOMA;

ADENOSINE TRIPHOSPHATASES; ANTINEOPLASTIC AGENTS; ATP-BINDING CASSETTE TRANSPORTERS; AZIDES; CELL SURVIVAL; CURCUMA; CURCUMIN; DRUG COMBINATIONS; DRUG INTERACTIONS; FLUORESCEINS; HUMANS; IODINE RADIOISOTOPES; KB CELLS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; P-GLYCOPROTEIN; PHOTOAFFINITY LABELS; PLANT EXTRACTS; PRAZOSIN; RHODAMINE 123; VINBLASTINE;

EID: 5144221545     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2004.07.009     Document Type: Article

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