Electrophysiology-based analysis of human histamine H4 receptor pharmacology using GIRK channel coupling in Xenopus oocytes

European Journal of Pharmacology

Volumn 591, Issue 1-3, 2008, Pages 52-58

  Sahlholm, Kristoffer ^a   Nilsson, Johanna ^a   Marcellino, Daniel ^a   Fuxe, Kjell ^a   Århem, Peter ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Clobenpropit; GIRK channel; Histamine H4 receptor; Thioperamide; Voltage clamp; Xenopus oocyte

Indexed keywords

ALPHA METHYLHISTAMINE; CLOBENPROPIT; COMPLEMENTARY RNA; G PROTEIN COUPLED INWARDLY RECTIFYING POTASSIUM CHANNEL; HISTAMINE; HISTAMINE H4 RECEPTOR; LIGAND; THIOPERAMIDE;

ANIMAL CELL; ARTICLE; ELECTROPHYSIOLOGY; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BINDING; RECEPTOR INTRINSIC ACTIVITY; VOLTAGE CLAMP; XENOPUS LAEVIS;

ANIMALS; ELECTROPHYSIOLOGY; G PROTEIN-COUPLED INWARDLY-RECTIFYING POTASSIUM CHANNELS; HISTAMINE AGONISTS; HISTAMINE ANTAGONISTS; HUMANS; IMIDAZOLES; METHYLHISTAMINES; OOCYTES; PATCH-CLAMP TECHNIQUES; PIPERIDINES; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, HISTAMINE; THIOUREA; XENOPUS;

EID: 48749092614     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2008.06.029     Document Type: Article

References (32)

1. + channels. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 6239-6244
2. Bradding P., Okayama Y., Kambe N., and Saito H. Ion channel gene expression in human lung, skin, and cord blood-derived mast cells. J. Leukoc. Biol. 73 (2003) 614-620
3. Breunig E., Michel K., Zeller F., Seidl S., Hann V., Weyhern C.W., and Schemann M. Histamine excites neurones in the human submucous plexus through activation of H1, H2, H3 and H4 receptors. J. Physiol. 583 (2007) 731-742
4. Buckland K.F., Williams T.J., and Conroy D.M. Histamine induces cytoskeletal changes in human eosinophils via the H(4) receptor. Br. J. Pharmacol. 140 (2003) 1117-1127
5. Dascal N. Ion-channel regulation by G proteins. Trends Endocrinol Metab. 12 (2001) 391-398
6. Doupnik C.A., Jaen C., and Zhang Q. Measuring the modulatory effects of RGS proteins on GIRK channels. Methods Enzymol. 389 (2004) 131-154
7. Esbenshade T.A., Krueger K.M., Miller T.R., Kang C.H., Denny L.I., Witte D.G., Yao B.B., Fox G.B., Faghih R., Bennani Y.L., Williams M., and Hancock A.A. Two novel and selective nonimidazole histamine H3 receptor antagonists A-304121 and A-317920: I. In vitro pharmacological effects. J. Pharmacol. Exp. Ther. 305 (2003) 887-896
8. Fuxe K., Canals M., Torvinen M., Marcellino D., Terasmaa A., Genedani S., Leo G., Guidolin D., Diaz-Cabiale Z., Rivera A., Lundstrom L., Langel U., Narvaez J., Tanganelli S., Lluis C., Ferre S., Woods A., Franco R., and Agnati L.F. Intramembrane receptor-receptor interactions: a novel principle in molecular medicine. J. Neural Transm. 114 (2007) 49-75
9. Gbahou F., Vincent L., Humbert-Claude M., Tardivel-Lacombe J., Chabret C., and Arrang J.M. Compared pharmacology of human histamine H3 and H4 receptors: structure-activity relationships of histamine derivatives. Br. J. Pharmacol. 147 (2006) 744-754
10. Gutzmer R., Diestel C., Mommert S., Kother B., Stark H., Wittmann M., and Werfel T. Histamine H4 receptor stimulation suppresses IL-12p70 production and mediates chemotaxis in human monocyte-derived dendritic cells. J. Immunol. 174 (2005) 5224-5532
11. Heusler P., Newman-Tancredi A., Castro-Fernandez A., and Cussac D. Differential agonist and inverse agonist profile of antipsychotics at D2L receptors coupled to GIRK potassium channels. Neuropharmacology 52 (2007) 1106-1113
12. Hofstra C.L., Desai P.J., Thurmond R.L., and Fung-Leung W.P. Histamine H4 receptor mediates chemotaxis and calcium mobilization of mast cells. J. Pharmacol. Exp. Ther. 305 (2003) 1212-1221
13. Kenakin T. Differences between natural and recombinant G protein-coupled receptor systems with varying receptor/G protein stoichiometry. Trends Pharmacol. Sci. 18 (1997) 456-464
14. Kenakin T. Efficacy as a vector: the relative prevalence and paucity of inverse agonism. Mol. Pharmacol. 65 (2004) 2-11
15. Kenakin T. Principles: receptor theory in pharmacology. Trends Pharmacol. Sci. 25 (2004) 186-192
16. Lim H.D., Smits R.A., Leurs R., and De Esch I.J. The emerging role of the histamine H4 receptor in anti-inflammatory therapy. Curr. Top. Med. Chem. 6 (2006) 1365-1373
17. Lim H.D., van Rijn R.M., Ling P., Bakker R.A., Thurmond R.L., and Leurs R. Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist. J. Pharmacol. Exp. Ther. 314 (2005) 1310-1321
18. Liu C., Ma X., Jiang X., Wilson S.J., Hofstra C.L., Blevitt J., Pyati J., Li X., Chai W., Carruthers N., and Lovenberg T.W. Cloning and pharmacological characterization of a fourth histamine receptor (H(4)) expressed in bone marrow. Mol. Pharmacol. 59 (2001) 420-426
19. Morse K.L., Behan J., Laz T.M., West Jr. R.E., Greenfeder S.A., Anthes J.C., Umland S., Wan Y., Hipkin R.W., Gonsiorek W., Shin N., Gustafson E.L., Qiao X., Wang S., Hedrick J.A., Greene J., Bayne M., and Monsma Jr. F.J. Cloning and characterization of a novel human histamine receptor. J. Pharmacol. Exp. Ther. 296 (2001) 1058-1066
20. Nakamura T., Itadani H., Hidaka Y., Ohta M., and Tanaka K. Molecular cloning and characterization of a new human histamine receptor, HH4R. Biochem. Biophys. Res. Commun. 279 (2000) 615-620
21. Nakaya M., Takeuchi N., and Kondo K. Immunohistochemical localization of histamine receptor subtypes in human inferior turbinates. Ann. Otol. Rhinol. Laryngol. 113 (2004) 552-557
22. Nguyen T., Shapiro D.A., George S.R., Setola V., Lee D.K., Cheng R., Rauser L., Lee S.P., Lynch K.R., Roth B.L., and O'Dowd B.F. Discovery of a novel member of the histamine receptor family. Mol. Pharmacol. 59 (2001) 427-433
23. Oda T., Morikawa N., Saito Y., Masuho Y., and Matsumoto S. Molecular cloning and characterization of a novel type of histamine receptor preferentially expressed in leukocytes. J. Biol. Chem. 275 (2000) 36781-36786
24. Persson A.S., Klement G., Almgren M., Sahlholm K., Nilsson J., Petersson S., Arhem P., Schalling M., and Lavebratt C. A truncated Kv1.1 protein in the brain of the megencephaly mouse: expression and interaction. B.M.C. Neurosci. 23 6 (2005) 65
25. Saito M., Sato R., Munoz N.M., Herrnreiter A., Oyaizu M., Kasugai H., Narahashi T., and Leff A.R. Association of granular exocytosis with Ca(2+)-activated K+ channels in human eosinophils. Am. J. Physiol. 273 (1997) L16-21
26. Sahlholm K., Nilsson J., Marcellino D., Fuxe K., and Arhem P. The human histamine H(3) receptor couples to GIRK channels in Xenopus oocytes. Eur. J. Pharmacol. 567 (2007) 206-210
27. Shankar H., Murugappan S., Kim S., Jin J., Ding Z., Wickman K., and Kunapuli S.P. Role of G protein-gated inwardly rectifying potassium channels in P2Y12 receptor-mediated platelet functional responses. Blood 104 (2004) 1335-1343
28. Tare M., Prestwich S.A., Gordienko D.V., Parveen S., Carver J.E., Robinson C., and Bolton T.B. Inwardly rectifying whole cell potassium current in human blood eosinophils. J. Physiol. 506 (1998) 303-318
29. van Rijn R.M., Chazot P.L., Shenton F.C., Sansuk K., Bakker R.A., and Leurs R. Oligomerization of recombinant and endogenously expressed human histamine H(4) receptors. Mol. Pharmacol. 70 (2006) 604-615
30. Wieland K., Bongers G., Yamamoto Y., Hashimoto T., Yamatodani A., Menge W.M., Timmerman H., Lovenberg T.W., and Leurs R. Constitutive activity of histamine h(3) receptors stably expressed in SK-N-MC cells: display of agonism and inverse agonism by H(3) antagonists. J. Pharmacol. Exp. Ther. 299 (2001) 908-914
31. Zhang M., Thurmond R.L., and Dunford P.J. The histamine H(4) receptor: a novel modulator of inflammatory and immune disorders. Pharmacol. Ther. 113 (2007) 594-606
32. Zhu Y., Michalovich D., Wu H., Tan K.B., Dytko G.M., Mannan I.J., Boyce R., Alston J., Tierney L.A., Li X., Herrity N.C., Vawter L., Sarau H.M., Ames R.S., Davenport C.M., Hieble J.P., Wilson S., Bergsma D.J., and Fitzgerald L.R. Cloning, expression, and pharmacological characterization of a novel human histamine receptor. Mol. Pharmacol. 59 (2001) 434-441