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Volumn 5, Issue 7, 2008, Pages 789-803

Recent developments in leishmaniasis vaccine delivery systems

Author keywords

Adjuvant; Cationic liposomes; Leishmania; Vaccine; Vaccine delivery systems

Indexed keywords

ALUMINUM POTASSIUM SULFATE; BACTERIAL VACCINE; BCG LEISHMANIA VACCINE; BCG VACCINE; CPG OLIGODEOXYNUCLEOTIDE; DENDRITIC CELL VACCINE; DIMYRISTOYLPHOSPHATIDYLCHOLINE; DIPALMITOYLPHOSPHATIDYLCHOLINE; DISTEAROYLPHOSPHATIDYLCHOLINE; DNA VACCINE; EMULSIFYING AGENT; FREUND ADJUVANT; INTERLEUKIN 2; LEISHMANIA HOMOLOG OF RECEPTOR FOR ACTIVATED C KINASE; LEISHMANIA VACCINE; LIPOSOME; LIVE VACCINE; MONTANIDE ISA 720; PHOSPHORYL LIPID A; POLOXAMER; RECOMBINANT INTERLEUKIN 2; SAPONIN; VIRUS VECTOR;

EID: 48449089960     PISSN: 17425247     EISSN: None     Source Type: Journal    
DOI: 10.1517/17425247.5.7.789     Document Type: Review
Times cited : (23)

References (118)
  • 1
    • 0344263897 scopus 로고    scopus 로고
    • homepage. Available from
    • World Health Organization [WHO], Leishmaniasis Control homepage. Available from: http://www.who.int/ctd/html/leish.html
    • Leishmaniasis Control
  • 2
    • 33846847777 scopus 로고    scopus 로고
    • Leishmania vaccines: Progress and problems
    • Kedzierski L, Zhu Y, Handman E. Leishmania vaccines: progress and problems. Parasitology 2006;133(Suppl):S87-112
    • (2006) Parasitology , vol.133 , Issue.SUPPL.
    • Kedzierski, L.1    Zhu, Y.2    Handman, E.3
  • 3
    • 17644416719 scopus 로고    scopus 로고
    • Targeting the innate immune response with improved vaccine adjuvants
    • Pashine A, Valiante NM, Ulmer JB. Targeting the innate immune response with improved vaccine adjuvants. Nat Med 2005;11:S63-8
    • (2005) Nat Med , vol.11
    • Pashine, A.1    Valiante, N.M.2    Ulmer, J.B.3
  • 4
    • 0034826521 scopus 로고    scopus 로고
    • Recent developments in adjuvants for vaccines against infectious diseases
    • O'Hagan DT, MacKichan ML, Singh M. Recent developments in adjuvants for vaccines against infectious diseases. Biomol Eng 2001;18:69-85
    • (2001) Biomol Eng , vol.18 , pp. 69-85
    • O'Hagan, D.T.1    MacKichan, M.L.2    Singh, M.3
  • 5
    • 0017577268 scopus 로고
    • Effect of treatment with BCG on the course of visceral leishmaniasis in BALB/c mice
    • Smrkovski LL, Larson CL. Effect of treatment with BCG on the course of visceral leishmaniasis in BALB/c mice. Infect Immun 1977;16:249-57
    • (1977) Infect Immun , vol.16 , pp. 249-257
    • Smrkovski, L.L.1    Larson, C.L.2
  • 6
    • 0017645481 scopus 로고
    • The effect of BCG on experimental cutaneous leishmaniasis in mice
    • Weintraub J, Weinbaum FI. The effect of BCG on experimental cutaneous leishmaniasis in mice. J Immunol 1977;118:2288-90
    • (1977) J Immunol , vol.118 , pp. 2288-2290
    • Weintraub, J.1    Weinbaum, F.I.2
  • 7
    • 0033660439 scopus 로고    scopus 로고
    • Safety and immunogenicity of a killed Leishmania (L) amazonensis vaccine against cutaneous leishmaniasis in Colombia: A randomized controlled trial
    • Vélez ID, del Pilar Agudelo S, Arbelaez MP, et al. Safety and immunogenicity of a killed Leishmania (L) amazonensis vaccine against cutaneous leishmaniasis in Colombia: a randomized controlled trial. Trans R Soc Trop Med Hyg 2000;94:698-703
    • (2000) Trans R Soc Trop Med Hyg , vol.94 , pp. 698-703
    • Vélez, I.D.1    del Pilar Agudelo, S.2    Arbelaez, M.P.3
  • 8
    • 1542360794 scopus 로고    scopus 로고
    • Safety, immunogenicity, and efficacy of an autoclaved Leishmania amazonensis vaccine plus BCG adjuvant against New World cutaneous leishmaniasis
    • Armijos RX, Weigel MM, Calvopina M, et al. Safety, immunogenicity, and efficacy of an autoclaved Leishmania amazonensis vaccine plus BCG adjuvant against New World cutaneous leishmaniasis. Vaccine 2004;22(9-10):1320-6
    • (2004) Vaccine , vol.22 , Issue.9-10 , pp. 1320-1326
    • Armijos, R.X.1    Weigel, M.M.2    Calvopina, M.3
  • 9
    • 0034605714 scopus 로고    scopus 로고
    • Autoclaved Leishmania major vaccine for prevention of visceral leishmaniasis: A randomised, double-blind, BCG-controlled trial in Sudan
    • Khalil EA, El Hassan AM, Zijlstra EE, et al. Autoclaved Leishmania major vaccine for prevention of visceral leishmaniasis: a randomised, double-blind, BCG-controlled trial in Sudan. Lancet 2000;356:1565-9
    • (2000) Lancet , vol.356 , pp. 1565-1569
    • Khalil, E.A.1    El Hassan, A.M.2    Zijlstra, E.E.3
  • 10
    • 1642458466 scopus 로고    scopus 로고
    • Immunotherapy of American cutaneous leishmaniasis in Venezuela during the period 1990-99
    • Convit J, Ulrich M, Zerpa O, et al. Immunotherapy of American cutaneous leishmaniasis in Venezuela during the period 1990-99. Trans R Soc Trop Med Hyg 2003;97:469-72
    • (2003) Trans R Soc Trop Med Hyg , vol.97 , pp. 469-472
    • Convit, J.1    Ulrich, M.2    Zerpa, O.3
  • 11
    • 1642526577 scopus 로고    scopus 로고
    • Therapy of Venezuelan patients with severe mucocutaneous or early lesions of diffuse cutaneous leishmaniasis with a vaccine containing pasteurized Leishmania promastigotes and bacillus Calmette-Guerin: Preliminary report
    • Convit J, Ulrich M, Polegre MA, et al. Therapy of Venezuelan patients with severe mucocutaneous or early lesions of diffuse cutaneous leishmaniasis with a vaccine containing pasteurized Leishmania promastigotes and bacillus Calmette-Guerin: preliminary report. Mem Inst Oswaldo Cruz 2004;99:57-62
    • (2004) Mem Inst Oswaldo Cruz , vol.99 , pp. 57-62
    • Convit, J.1    Ulrich, M.2    Polegre, M.A.3
  • 12
    • 0037456693 scopus 로고    scopus 로고
    • A Leishmania infantum multi-component antigenic protein mixed with live BCG confers protection to dogs experimentally infected with L. infantum
    • Molano I, Alonso MG, Mirón C, et al. A Leishmania infantum multi-component antigenic protein mixed with live BCG confers protection to dogs experimentally infected with L. infantum. Vet Immunol Immunopathol 2003;92:1-13
    • (2003) Vet Immunol Immunopathol , vol.92 , pp. 1-13
    • Molano, I.1    Alonso, M.G.2    Mirón, C.3
  • 13
    • 0035850989 scopus 로고    scopus 로고
    • Immunization with A2 protein results in a mixed Th1/Th2 and a humoral response which protects mice against Leishmania donovani infections
    • Ghosh A, Zhang WW, Matlashewski G. Immunization with A2 protein results in a mixed Th1/Th2 and a humoral response which protects mice against Leishmania donovani infections. Vaccine 2001;20:59-66
    • (2001) Vaccine , vol.20 , pp. 59-66
    • Ghosh, A.1    Zhang, W.W.2    Matlashewski, G.3
  • 14
    • 0035858116 scopus 로고    scopus 로고
    • Successful vaccination against Leishmania donovani infection in Indian langur using alum-precipitated autoclaved Leishmania major with BCG
    • Misra A, Dube A, Srivastava B, et al. Successful vaccination against Leishmania donovani infection in Indian langur using alum-precipitated autoclaved Leishmania major with BCG. Vaccine 2001;19:3485-92
    • (2001) Vaccine , vol.19 , pp. 3485-3492
    • Misra, A.1    Dube, A.2    Srivastava, B.3
  • 15
    • 4444327985 scopus 로고    scopus 로고
    • Alum-precipitated autoclaved Leishmania major plus bacille Calmette-Guérrin, a candidate vaccine for visceral leishmaniasis: Safety, skin-delayed type hypersensitivity response and dose finding in healthy volunteers
    • Kamil AA, Khalil EA, Musa AM, et al. Alum-precipitated autoclaved Leishmania major plus bacille Calmette-Guérrin, a candidate vaccine for visceral leishmaniasis: safety, skin-delayed type hypersensitivity response and dose finding in healthy volunteers. Trans R Soc Trop Med Hyg 2003;97(3):365-8
    • (2003) Trans R Soc Trop Med Hyg , vol.97 , Issue.3 , pp. 365-368
    • Kamil, A.A.1    Khalil, E.A.2    Musa, A.M.3
  • 16
    • 36549028707 scopus 로고    scopus 로고
    • Immunochemotherapy of persistent post-kala-azar dermal leishmaniasis: A novel approach to treatment
    • Musa AM, Khalil EA, Mahgoub FA, et al. Immunochemotherapy of persistent post-kala-azar dermal leishmaniasis: a novel approach to treatment. Trans R Soc Trop Med Hyg 2008;102:58-63
    • (2008) Trans R Soc Trop Med Hyg , vol.102 , pp. 58-63
    • Musa, A.M.1    Khalil, E.A.2    Mahgoub, F.A.3
  • 17
    • 0033522819 scopus 로고    scopus 로고
    • Vaccination of Swiss Albino mice against experimental visceral leishmaniasis with the FML antigen of Leishmania donovani
    • Santos WR, Paraguai de Souza E, Palatnik M, Palatnik de Sousa CB. Vaccination of Swiss Albino mice against experimental visceral leishmaniasis with the FML antigen of Leishmania donovani. Vaccine 1999;172554-61
    • (1999) Vaccine , pp. 172554-172561
    • Santos, W.R.1    Paraguai de Souza, E.2    Palatnik, M.3    Palatnik de Sousa, C.B.4
  • 18
    • 0037159626 scopus 로고    scopus 로고
    • Saponins, IL12 and BCG adjuvant in the FML-vaccine formulation against murine visceral leishmaniasis
    • Santos WR, de Lima VM, de Souza EP, et al. Saponins, IL12 and BCG adjuvant in the FML-vaccine formulation against murine visceral leishmaniasis. Vaccine 2002;21:30-43
    • (2002) Vaccine , vol.21 , pp. 30-43
    • Santos, W.R.1    de Lima, V.M.2    de Souza, E.P.3
  • 19
    • 33646135059 scopus 로고    scopus 로고
    • Acylated and deacylated saponins of Quillaja saponaria mixture as adjuvants for the FML-vaccine against visceral leishmaniasis
    • Oliveira-Freitas E, Casas CP, Borja-Cabrera GP et al. Acylated and deacylated saponins of Quillaja saponaria mixture as adjuvants for the FML-vaccine against visceral leishmaniasis. Vaccine 2006;24:3909-20
    • (2006) Vaccine , vol.24 , pp. 3909-3920
    • Oliveira-Freitas, E.1    Casas, C.P.2    Borja-Cabrera, G.P.3
  • 20
    • 0037055992 scopus 로고    scopus 로고
    • Long lasting protection against canine kala-azar using the FML-QuilA saponin vaccine in an endemic area of Brazil (São Gonçalo do Amarante, RN)
    • Borja-Cabrera GP, Correia Pontes NN, da Silva VO, et al. Long lasting protection against canine kala-azar using the FML-QuilA saponin vaccine in an endemic area of Brazil (São Gonçalo do Amarante, RN). Vaccine 2002;20:3277-84
    • (2002) Vaccine , vol.20 , pp. 3277-3284
    • Borja-Cabrera, G.P.1    Correia Pontes, N.N.2    da Silva, V.O.3
  • 21
    • 0242320930 scopus 로고    scopus 로고
    • Immunotherapy against murine experimental visceral leishmaniasis with the FML-vaccine
    • Santos WR, Aguiar IA, Paraguai de Souza E, et al. Immunotherapy against murine experimental visceral leishmaniasis with the FML-vaccine. Vaccine 2003;21:4668-76
    • (2003) Vaccine , vol.21 , pp. 4668-4676
    • Santos, W.R.1    Aguiar, I.A.2    Paraguai de Souza, E.3
  • 22
    • 2442716621 scopus 로고    scopus 로고
    • Effective immunotherapy against canine visceral leishmaniasis with the FML-vaccine
    • Borja-Cabrera GP, Cruz Mendes A, Paraguai de Souza E, et al. Effective immunotherapy against canine visceral leishmaniasis with the FML-vaccine. Vaccine 2004;22:2234-43
    • (2004) Vaccine , vol.22 , pp. 2234-2243
    • Borja-Cabrera, G.P.1    Cruz Mendes, A.2    Paraguai de Souza, E.3
  • 23
    • 0033953695 scopus 로고    scopus 로고
    • Subunit vaccination of mice against new world cutaneous leishmaniasis: Comparison of three proteins expressed in amastigotes and six adjuvants
    • Aebischer T, Wolfram M, Patzer SI, et al. Subunit vaccination of mice against new world cutaneous leishmaniasis: comparison of three proteins expressed in amastigotes and six adjuvants. Infect Immun 2000;68:1328-36
    • (2000) Infect Immun , vol.68 , pp. 1328-1336
    • Aebischer, T.1    Wolfram, M.2    Patzer, S.I.3
  • 24
    • 0031842834 scopus 로고    scopus 로고
    • Human and murine immune responses to a novel Leishmania major recombinant protein encoded by members of a multicopy gene family
    • Webb JR, Campos-Neto A, Ovendale PJ, et al. Human and murine immune responses to a novel Leishmania major recombinant protein encoded by members of a multicopy gene family. Infect Immun 1998;66(7):3279-89
    • (1998) Infect Immun , vol.66 , Issue.7 , pp. 3279-3289
    • Webb, J.R.1    Campos-Neto, A.2    Ovendale, P.J.3
  • 25
    • 0035001263 scopus 로고    scopus 로고
    • Protection against cutaneous leishmaniasis induced by recombinant antigens in murine and nonhuman primate models of the human disease
    • Campos-Neto A, Porrozzi R, Greeson K, et al. Protection against cutaneous leishmaniasis induced by recombinant antigens in murine and nonhuman primate models of the human disease. Infect Immun 2001;69:4103-8
    • (2001) Infect Immun , vol.69 , pp. 4103-4108
    • Campos-Neto, A.1    Porrozzi, R.2    Greeson, K.3
  • 26
    • 0035898935 scopus 로고    scopus 로고
    • Paradoxical effects of IL-12 in leishmaniasis in the presence and absence of vaccinating antigen
    • Noormohammadi AH, Hochrein H, Curtis JM, et al. Paradoxical effects of IL-12 in leishmaniasis in the presence and absence of vaccinating antigen. Vaccine 2001;19:4043-52
    • (2001) Vaccine , vol.19 , pp. 4043-4052
    • Noormohammadi, A.H.1    Hochrein, H.2    Curtis, J.M.3
  • 27
    • 0031757985 scopus 로고    scopus 로고
    • Vaccine requirements for sustained cellular immunity to an intracellular parasitic infection
    • Gurunathan S, Prussin C, Sacks DL, Seder RA. Vaccine requirements for sustained cellular immunity to an intracellular parasitic infection. Nat Med 1998;4:1409-15
    • (1998) Nat Med , vol.4 , pp. 1409-1415
    • Gurunathan, S.1    Prussin, C.2    Sacks, D.L.3    Seder, R.A.4
  • 28
    • 17444429293 scopus 로고    scopus 로고
    • Second-generation vaccines against leishmaniasis
    • Coler RN, Reed SG. Second-generation vaccines against leishmaniasis. Trends Parasitol 2005;21:244-9
    • (2005) Trends Parasitol , vol.21 , pp. 244-249
    • Coler, R.N.1    Reed, S.G.2
  • 29
    • 0036073291 scopus 로고    scopus 로고
    • Immunization with a polyprotein vaccine consisting of the T-Cell antigens thiol-specific antioxidant, Leishmania major stress-inducible protein 1, and Leishmania elongation initiation factor protects against leishmaniasis
    • Coler RN, Skeiky YA, Bernards K, et al. Immunization with a polyprotein vaccine consisting of the T-Cell antigens thiol-specific antioxidant, Leishmania major stress-inducible protein 1, and Leishmania elongation initiation factor protects against leishmaniasis. Infect Immun 2002;70:4215-25
    • (2002) Infect Immun , vol.70 , pp. 4215-4225
    • Coler, R.N.1    Skeiky, Y.A.2    Bernards, K.3
  • 30
    • 0037055963 scopus 로고    scopus 로고
    • Protective efficacy of a tandemly linked, multi-subunit recombinant leishmanial vaccine (Leish-111f) formulated in MPL adjuvant
    • Skeiky YA, Coler RN, Brannon M, et al. Protective efficacy of a tandemly linked, multi-subunit recombinant leishmanial vaccine (Leish-111f) formulated in MPL adjuvant. Vaccine 2002;20:3292-303
    • (2002) Vaccine , vol.20 , pp. 3292-3303
    • Skeiky, Y.A.1    Coler, R.N.2    Brannon, M.3
  • 31
    • 34547870667 scopus 로고    scopus 로고
    • Leish-111f, a recombinant polyprotein vaccine that protects against visceral leishmaniasis by elicitation of CD4+ T cells
    • Coler RN, Goto Y, Bogatzki L, et al. Leish-111f, a recombinant polyprotein vaccine that protects against visceral leishmaniasis by elicitation of CD4+ T cells. Infect Immun 2007;75:4648-54
    • (2007) Infect Immun , vol.75 , pp. 4648-4654
    • Coler, R.N.1    Goto, Y.2    Bogatzki, L.3
  • 32
    • 26644448719 scopus 로고    scopus 로고
    • Failure of a multi-subunit recombinant leishmanial vaccine (MML) to protect dogs from Leishmania infantum infection and to prevent disease progression in infected animals
    • Gradoni L, Foglia Manzillo V, Pagano A, et al. Failure of a multi-subunit recombinant leishmanial vaccine (MML) to protect dogs from Leishmania infantum infection and to prevent disease progression in infected animals. Vaccine 2005;23:5245-51
    • (2005) Vaccine , vol.23 , pp. 5245-5251
    • Gradoni, L.1    Foglia Manzillo, V.2    Pagano, A.3
  • 33
    • 35148820174 scopus 로고    scopus 로고
    • Consultation meeting on the development of therapeutic vaccines for post-kala azar dermal leishmaniasis
    • Ghalib H, Modabber F. Consultation meeting on the development of therapeutic vaccines for post-kala azar dermal leishmaniasis. Kinetoplastid Biol Dis 2007;6:7
    • (2007) Kinetoplastid Biol Dis , vol.6 , pp. 7
    • Ghalib, H.1    Modabber, F.2
  • 34
    • 0032521881 scopus 로고    scopus 로고
    • CpG oligodeoxynucleotides trigger protective and curative Th1 responses in lethal murine leishmaniasis
    • Zimmermann S, Egeter O, Hausmann S, et al. CpG oligodeoxynucleotides trigger protective and curative Th1 responses in lethal murine leishmaniasis. J Immunol 1998;160:3627-30
    • (1998) J Immunol , vol.160 , pp. 3627-3630
    • Zimmermann, S.1    Egeter, O.2    Hausmann, S.3
  • 35
    • 0033536013 scopus 로고    scopus 로고
    • Immunostimulatory oligodeoxynucleotides promote protective immunity and provide systemic therapy for leishmaniasis via IL-12- and IFN-gamma-dependent mechanisms
    • Walker PS, Scharton-Kersten T, Krieg AM, et al. Immunostimulatory oligodeoxynucleotides promote protective immunity and provide systemic therapy for leishmaniasis via IL-12- and IFN-gamma-dependent mechanisms. Proc Natl Acad Sci USA 1999;96:6970-5
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 6970-6975
    • Walker, P.S.1    Scharton-Kersten, T.2    Krieg, A.M.3
  • 36
    • 0037124332 scopus 로고    scopus 로고
    • Vaccination with heat-killed Leishmania antigen or recombinant leishmanial protein and CpG oligodeoxynucleotides induces long-term memory CD4+ and CD8+ T cell responses and protection against Leishmania major infection
    • Rhee EG, Mendez S, Shah JA, et al. Vaccination with heat-killed Leishmania antigen or recombinant leishmanial protein and CpG oligodeoxynucleotides induces long-term memory CD4+ and CD8+ T cell responses and protection against Leishmania major infection. J Exp Med 2002;195:1565-73
    • (2002) J Exp Med , vol.195 , pp. 1565-1573
    • Rhee, E.G.1    Mendez, S.2    Shah, J.A.3
  • 37
    • 23344435672 scopus 로고    scopus 로고
    • Prevention and treatment of cutaneous leishmaniasis in primates by using synthetic type D/A oligodeoxynucleotides expressing CpG motifs
    • Flynn B, Wang V, Sacks DL, et al. Prevention and treatment of cutaneous leishmaniasis in primates by using synthetic type D/A oligodeoxynucleotides expressing CpG motifs. Infect Immun 2005;73:4948-54
    • (2005) Infect Immun , vol.73 , pp. 4948-4954
    • Flynn, B.1    Wang, V.2    Sacks, D.L.3
  • 38
    • 0034142182 scopus 로고    scopus 로고
    • Delineation of a CpG phosphorothioate oligodeoxynucleotide for activating primate immune responses in vitro and in vivo
    • Hartmann G, Weeratna RD, Ballas ZK, et al. Delineation of a CpG phosphorothioate oligodeoxynucleotide for activating primate immune responses in vitro and in vivo. J Immunol 2000;164:1617-24
    • (2000) J Immunol , vol.164 , pp. 1617-1624
    • Hartmann, G.1    Weeratna, R.D.2    Ballas, Z.K.3
  • 39
    • 0037407856 scopus 로고    scopus 로고
    • CpG oligodeoxynucleotides protect normal and SIV-infected macaques from Leishmania infection
    • Verthelyi D, Gursel M, Kenney RT, et al. CpG oligodeoxynucleotides protect normal and SIV-infected macaques from Leishmania infection. J Immunol 2003;170:4717-23
    • (2003) J Immunol , vol.170 , pp. 4717-4723
    • Verthelyi, D.1    Gursel, M.2    Kenney, R.T.3
  • 40
    • 0041322722 scopus 로고    scopus 로고
    • Coinjection with CpG-containing immunostimulatory oligodeoxynucleotides reduces the pathogenicity of a live vaccine against cutaneous leishmaniasis but maintains its potency and durability
    • Mendez S, Tabbara K, Belkaid Y, et al. Coinjection with CpG-containing immunostimulatory oligodeoxynucleotides reduces the pathogenicity of a live vaccine against cutaneous leishmaniasis but maintains its potency and durability. Infect Immun 2003;71:5121-9
    • (2003) Infect Immun , vol.71 , pp. 5121-5129
    • Mendez, S.1    Tabbara, K.2    Belkaid, Y.3
  • 41
    • 33845578705 scopus 로고    scopus 로고
    • Immunomodulatory effects associated with a live vaccine against Leishmania major containing CpG oligodeoxynucleotides
    • Wu W, Weigand L, Belkaid Y, Mendez S. Immunomodulatory effects associated with a live vaccine against Leishmania major containing CpG oligodeoxynucleotides. Eur J Immunol 2006;36:3238-47
    • (2006) Eur J Immunol , vol.36 , pp. 3238-3247
    • Wu, W.1    Weigand, L.2    Belkaid, Y.3    Mendez, S.4
  • 42
    • 0027141144 scopus 로고
    • Effective immunization against cutaneous leishmaniasis with recombinant bacille Calmette-Guérin expressing the Leishmania surface proteinase gp63
    • Connell ND, Medina-Acosta E, McMaster WR, et al. Effective immunization against cutaneous leishmaniasis with recombinant bacille Calmette-Guérin expressing the Leishmania surface proteinase gp63. Proc Natl Acad Sci USA 1993;90:11473-7
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 11473-11477
    • Connell, N.D.1    Medina-Acosta, E.2    McMaster, W.R.3
  • 43
    • 0033959560 scopus 로고    scopus 로고
    • BCG expressing LCR1 of Leishmania chagasi induces protective immunity in susceptible mice
    • Streit JA, Recker TJ, Donelson JE, Wilson ME. BCG expressing LCR1 of Leishmania chagasi induces protective immunity in susceptible mice. Exp Parasitol 2000;94:33-41
    • (2000) Exp Parasitol , vol.94 , pp. 33-41
    • Streit, J.A.1    Recker, T.J.2    Donelson, J.E.3    Wilson, M.E.4
  • 44
    • 0025178056 scopus 로고
    • Oral Salmonella typhimurium (AroA-) vaccine expressing a major leishmanial surface protein (gp63) preferentially induces T helper 1 cells and protective immunity against leishmaniasis
    • Yang DM, Fairweather N, Button LL, et al. Oral Salmonella typhimurium (AroA-) vaccine expressing a major leishmanial surface protein (gp63) preferentially induces T helper 1 cells and protective immunity against leishmaniasis. J Immunol 1990;145:2281-5
    • (1990) J Immunol , vol.145 , pp. 2281-2285
    • Yang, D.M.1    Fairweather, N.2    Button, L.L.3
  • 45
    • 0033961616 scopus 로고    scopus 로고
    • Listeria monocytogenes as a short-lived delivery system for the induction of type 1 cell-mediated immunity against the p36/LACK antigen of Leishmania major
    • Soussi N, Milon G, Colle JH, et al. Listeria monocytogenes as a short-lived delivery system for the induction of type 1 cell-mediated immunity against the p36/LACK antigen of Leishmania major. Infect Immun 2000;68:1498-506
    • (2000) Infect Immun , vol.68 , pp. 1498-1506
    • Soussi, N.1    Milon, G.2    Colle, J.H.3
  • 46
    • 0035851346 scopus 로고    scopus 로고
    • Attenuated Toxoplasma gondii ts-4 mutants engineered to express the Leishmania antigen KMP-11 elicit a specific immune response in BALB/c mice
    • Ramírez JR, Gilchrist K, Robledo S, Sepúlveda, et al. Attenuated Toxoplasma gondii ts-4 mutants engineered to express the Leishmania antigen KMP-11 elicit a specific immune response in BALB/c mice. Vaccine 2001;20:455-61
    • (2001) Vaccine , vol.20 , pp. 455-461
    • Ramírez, J.R.1    Gilchrist, K.2    Robledo, S.3    Sepúlveda4
  • 47
    • 0032704475 scopus 로고    scopus 로고
    • The protective capacities of histone H1 against experimental murine cutaneous leishmaniasis
    • Solioz N, Blum-Tirouvanziam U, Jacquet R, et al. The protective capacities of histone H1 against experimental murine cutaneous leishmaniasis. Vaccine 1999;18:850-9
    • (1999) Vaccine , vol.18 , pp. 850-859
    • Solioz, N.1    Blum-Tirouvanziam, U.2    Jacquet, R.3
  • 48
    • 0242333153 scopus 로고    scopus 로고
    • Masina S, M Gicheru M, Demotz SO, Fasel NJ. Protection against cutaneous leishmaniasis in outbred vervet monkeys using a recombinant histone H1 antigen. J Infect Dis 2003;188:1250-7
    • Masina S, M Gicheru M, Demotz SO, Fasel NJ. Protection against cutaneous leishmaniasis in outbred vervet monkeys using a recombinant histone H1 antigen. J Infect Dis 2003;188:1250-7
  • 49
    • 0033577295 scopus 로고    scopus 로고
    • Long-term protection of mice against Leishmania major with a synthetic peptide vaccine
    • Spitzer N, Jardim A, Lippert D, Olafson RW. Long-term protection of mice against Leishmania major with a synthetic peptide vaccine. Vaccine 1999;17:1298-300
    • (1999) Vaccine , vol.17 , pp. 1298-1300
    • Spitzer, N.1    Jardim, A.2    Lippert, D.3    Olafson, R.W.4
  • 50
    • 0037035854 scopus 로고    scopus 로고
    • Recombinant cysteine proteinases-based vaccines against Leishmania major in BALB/c mice: The partial protection relies on interferon gamma producing CD8(+) T lymphocyte activation
    • Rafati S, Kariminia A, Seyde-Eslami S, et al. Recombinant cysteine proteinases-based vaccines against Leishmania major in BALB/c mice: the partial protection relies on interferon gamma producing CD8(+) T lymphocyte activation. Vaccine 2002;20:2439-47
    • (2002) Vaccine , vol.20 , pp. 2439-2447
    • Rafati, S.1    Kariminia, A.2    Seyde-Eslami, S.3
  • 51
    • 2342461107 scopus 로고    scopus 로고
    • Immunization with the hybrid protein vaccine, consisting of Leishmania major cysteine proteinaaes Type I (CPB) and Type II (CPA), partially protects against leishmaniasis
    • Zadeh-Vakili A, Taheri T, Taslimi Y, et al. Immunization with the hybrid protein vaccine, consisting of Leishmania major cysteine proteinaaes Type I (CPB) and Type II (CPA), partially protects against leishmaniasis. Vaccine 2004;22:1930-40
    • (2004) Vaccine , vol.22 , pp. 1930-1940
    • Zadeh-Vakili, A.1    Taheri, T.2    Taslimi, Y.3
  • 52
    • 2942557170 scopus 로고    scopus 로고
    • DNA vaccines and adjuvants
    • Stevenson FK. DNA vaccines and adjuvants. Immunol Rev 2004;199:5-8
    • (2004) Immunol Rev , vol.199 , pp. 5-8
    • Stevenson, F.K.1
  • 54
    • 0036085692 scopus 로고    scopus 로고
    • Prime-boost immunization strategies for infectious diseases
    • McShane H. Prime-boost immunization strategies for infectious diseases. Curr Opin Mol Ther 2002;4:23-7
    • (2002) Curr Opin Mol Ther , vol.4 , pp. 23-27
    • McShane, H.1
  • 56
    • 36549027818 scopus 로고    scopus 로고
    • CD8 cytotoxic T cells in cutaneous leishmaniasis
    • Ruiz JH, Becker I. CD8 cytotoxic T cells in cutaneous leishmaniasis. Parasite Immunol 2007;29:671-8
    • (2007) Parasite Immunol , vol.29 , pp. 671-678
    • Ruiz, J.H.1    Becker, I.2
  • 57
    • 0027997083 scopus 로고
    • Genetic vaccination against leishmaniasis
    • Xu D, Liew FY. Genetic vaccination against leishmaniasis. Vaccine 1994;2:1534-6
    • (1994) Vaccine , vol.2 , pp. 1534-1536
    • Xu, D.1    Liew, F.Y.2
  • 58
    • 1842584437 scopus 로고    scopus 로고
    • A comparative evaluation of different DNA vaccine candidates against experimental murine leishmaniasis due to L. major
    • Ahmed SB, Bahloul C, Robbana C, et al. A comparative evaluation of different DNA vaccine candidates against experimental murine leishmaniasis due to L. major. Vaccine 2004;22:1631-9
    • (2004) Vaccine , vol.22 , pp. 1631-1639
    • Ahmed, S.B.1    Bahloul, C.2    Robbana, C.3
  • 59
    • 0032388140 scopus 로고    scopus 로고
    • Vaccination with recombinant parasite surface antigen 2 from Leishmania major induces a Th1 type of immune response but does not protect against infection
    • Sjölander A, Baldwin TM, Curtis JM, et al. Vaccination with recombinant parasite surface antigen 2 from Leishmania major induces a Th1 type of immune response but does not protect against infection. Vaccine 1998;16:2077-84
    • (1998) Vaccine , vol.16 , pp. 2077-2084
    • Sjölander, A.1    Baldwin, T.M.2    Curtis, J.M.3
  • 60
    • 0034237654 scopus 로고    scopus 로고
    • Therapy of murine cutaneous leishmaniasis by DNA vaccination
    • Handman E, Noormohammadi AH, Curtis JM, et al. Therapy of murine cutaneous leishmaniasis by DNA vaccination. Vaccine 2000;18:3011-7
    • (2000) Vaccine , vol.18 , pp. 3011-3017
    • Handman, E.1    Noormohammadi, A.H.2    Curtis, J.M.3
  • 61
    • 0037449085 scopus 로고    scopus 로고
    • DNA vaccines induce partial protection against Leishmania mexicana
    • Dumonteil E, Maria Jesus RS, Javier EO, et al. DNA vaccines induce partial protection against Leishmania mexicana. Vaccine 2003;21:2161-8
    • (2003) Vaccine , vol.21 , pp. 2161-2168
    • Dumonteil, E.1    Maria Jesus, R.S.2    Javier, E.O.3
  • 62
    • 0030822043 scopus 로고    scopus 로고
    • Vaccination with DNA encoding the immunodominant LACK parasite antigen confers protective immunity to mice infected with Leishmania major
    • Gurunathan S, Sacks DL, Brown DR, et al. Vaccination with DNA encoding the immunodominant LACK parasite antigen confers protective immunity to mice infected with Leishmania major. J Exp Med 1997;186:1137-47
    • (1997) J Exp Med , vol.186 , pp. 1137-1147
    • Gurunathan, S.1    Sacks, D.L.2    Brown, D.R.3
  • 63
    • 0037073555 scopus 로고    scopus 로고
    • DNA vaccination with linear minimalistic (MIDGE) vectors confers protection against Leishmania major infection in mice
    • López-Fuertes L, Pérez-Jiménez E, Vila-Coro AJ, et al. DNA vaccination with linear minimalistic (MIDGE) vectors confers protection against Leishmania major infection in mice. Vaccine 2002; 21:247-57
    • (2002) Vaccine , vol.21 , pp. 247-257
    • López-Fuertes, L.1    Pérez-Jiménez, E.2    Vila-Coro, A.J.3
  • 64
    • 3342986328 scopus 로고    scopus 로고
    • Intranasal vaccination against cutaneous leishmaniasis with a particulated leishmanial antigen or DNA encoding LACK
    • Pinto EF, Pinheiro RO, Rayol A, et al. Intranasal vaccination against cutaneous leishmaniasis with a particulated leishmanial antigen or DNA encoding LACK. Infect Immun 2004;72:4521-7
    • (2004) Infect Immun , vol.72 , pp. 4521-4527
    • Pinto, E.F.1    Pinheiro, R.O.2    Rayol, A.3
  • 65
    • 0034911854 scopus 로고    scopus 로고
    • Leishmania donovani p36 (LACK) DNA vaccine is highly immunogenic but not protective against experimental visceral leishmaniasis
    • Melby PC, Yang J, Zhao W, et al. Leishmania donovani p36 (LACK) DNA vaccine is highly immunogenic but not protective against experimental visceral leishmaniasis. Infect Immun 2001;69:4719-25
    • (2001) Infect Immun , vol.69 , pp. 4719-4725
    • Melby, P.C.1    Yang, J.2    Zhao, W.3
  • 66
    • 27944452329 scopus 로고    scopus 로고
    • Intramuscular immunization with p36(LACK) DNA vaccine induces IFN-gamma production but does not protect BALB/c mice against Leishmania chagasi intravenous challenge
    • Marques-da-Silva EA, Coelho EA, Gomes DC, et al. Intramuscular immunization with p36(LACK) DNA vaccine induces IFN-gamma production but does not protect BALB/c mice against Leishmania chagasi intravenous challenge. Parasitol Res 2005;98:67-74
    • (2005) Parasitol Res , vol.98 , pp. 67-74
    • Marques-da-Silva, E.A.1    Coelho, E.A.2    Gomes, D.C.3
  • 67
    • 0242349620 scopus 로고    scopus 로고
    • The Leishmania infantum acidic ribosomal protein P0 administered as a DNA vaccine confers protective immunity to Leishmania major infection in BALB/c mice
    • Iborra S, Soto M, Carrión J, et al. The Leishmania infantum acidic ribosomal protein P0 administered as a DNA vaccine confers protective immunity to Leishmania major infection in BALB/c mice. Infect Immun 2003;71:6562-72
    • (2003) Infect Immun , vol.71 , pp. 6562-6572
    • Iborra, S.1    Soto, M.2    Carrión, J.3
  • 68
    • 0242286560 scopus 로고    scopus 로고
    • DNA immunization with the gene encoding P4 nuclease of Leishmania amazonensis protects mice against cutaneous leishmaniasis
    • Campbell K, Diao H, Ji J, Soong L. DNA immunization with the gene encoding P4 nuclease of Leishmania amazonensis protects mice against cutaneous leishmaniasis. Infect Immun 2003;71:6270-8
    • (2003) Infect Immun , vol.71 , pp. 6270-6278
    • Campbell, K.1    Diao, H.2    Ji, J.3    Soong, L.4
  • 69
    • 0035858106 scopus 로고    scopus 로고
    • A protective cocktail vaccine against murine cutaneous leishmaniasis with DNA encoding cysteine proteinases of Leishmania major
    • Rafati S, Salmanian AH, Taheri T, et al. A protective cocktail vaccine against murine cutaneous leishmaniasis with DNA encoding cysteine proteinases of Leishmania major. Vaccine 2001;19:3369-75
    • (2001) Vaccine , vol.19 , pp. 3369-3375
    • Rafati, S.1    Salmanian, A.H.2    Taheri, T.3
  • 70
    • 4444242838 scopus 로고    scopus 로고
    • Vaccination with a plasmid DNA cocktail encoding the nucleosomal histones of Leishmania confers protection against murine cutaneous leishmaniasis
    • Iborra S, Soto M, Carrión J, et al. Vaccination with a plasmid DNA cocktail encoding the nucleosomal histones of Leishmania confers protection against murine cutaneous leishmaniasis. Vaccine 2004;22:3865-76
    • (2004) Vaccine , vol.22 , pp. 3865-3876
    • Iborra, S.1    Soto, M.2    Carrión, J.3
  • 71
    • 42649113387 scopus 로고    scopus 로고
    • Immunization strategies against visceral leishmaniasis with the nucleosomal histones of Leishmania infantum encoded in DNA vaccine or pulsed in dendritic cells
    • Carrión J, Folgueira C, Alonso C. Immunization strategies against visceral leishmaniasis with the nucleosomal histones of Leishmania infantum encoded in DNA vaccine or pulsed in dendritic cells. Vaccine 2008;26:2537-44
    • (2008) Vaccine , vol.26 , pp. 2537-2544
    • Carrión, J.1    Folgueira, C.2    Alonso, C.3
  • 72
    • 0035972008 scopus 로고    scopus 로고
    • Protection against Leishmania donovani infection by DNA vaccination: Increased DNA vaccination efficiency through inhibiting the cellular p53 response
    • Ghosh A, Labrecque S, Matlashewski G. Protection against Leishmania donovani infection by DNA vaccination: increased DNA vaccination efficiency through inhibiting the cellular p53 response. Vaccine 2001;19:3169-78
    • (2001) Vaccine , vol.19 , pp. 3169-3178
    • Ghosh, A.1    Labrecque, S.2    Matlashewski, G.3
  • 73
    • 34548096105 scopus 로고    scopus 로고
    • Evaluation of immune responses and protection induced by A2 and nucleoside hydrolase (NH) DNA vaccines against Leishmania chagasi and Leishmania amazonensis experimental infections
    • Zanin FH, Coelho EA, Tavares CA, et al. Evaluation of immune responses and protection induced by A2 and nucleoside hydrolase (NH) DNA vaccines against Leishmania chagasi and Leishmania amazonensis experimental infections. Microbes Infect 2007;9:1070-7
    • (2007) Microbes Infect , vol.9 , pp. 1070-1077
    • Zanin, F.H.1    Coelho, E.A.2    Tavares, C.A.3
  • 74
    • 0037424132 scopus 로고    scopus 로고
    • Vaccination with DNA encoding ORFF antigen confers protective immunity in mice infected with Leishmania donovani
    • Sukumaran B, Tewary P, Saxena S, Madhubala R. Vaccination with DNA encoding ORFF antigen confers protective immunity in mice infected with Leishmania donovani. Vaccine 2003;21:1292-9
    • (2003) Vaccine , vol.21 , pp. 1292-1299
    • Sukumaran, B.1    Tewary, P.2    Saxena, S.3    Madhubala, R.4
  • 75
    • 33344475047 scopus 로고    scopus 로고
    • Co-administration of IL-12 DNA with rORFF antigen confers long-term protective immunity against experimental visceral leishmaniaisis
    • Tewary P, Saxena S, Madhubala R. Co-administration of IL-12 DNA with rORFF antigen confers long-term protective immunity against experimental visceral leishmaniaisis. Vaccine 2006;24:2409-16
    • (2006) Vaccine , vol.24 , pp. 2409-2416
    • Tewary, P.1    Saxena, S.2    Madhubala, R.3
  • 76
    • 18944378937 scopus 로고    scopus 로고
    • Kinetoplastid membrane protein-11 DNA vaccination induces complete protection against both pentavalent antimonial-sensitive and -resistant strains of Leishmania donovani that correlates with inducible nitric oxide synthase activity and IL-4 generation: Evidence for mixed Th1- and Th2-like responses in visceral leishmaniasis
    • Basu R, Bhaumik S, Basu JM, et al. Kinetoplastid membrane protein-11 DNA vaccination induces complete protection against both pentavalent antimonial-sensitive and -resistant strains of Leishmania donovani that correlates with inducible nitric oxide synthase activity and IL-4 generation: evidence for mixed Th1- and Th2-like responses in visceral leishmaniasis. J Immunol 2005;174:7160-71
    • (2005) J Immunol , vol.174 , pp. 7160-7171
    • Basu, R.1    Bhaumik, S.2    Basu, J.M.3
  • 77
    • 12844258219 scopus 로고    scopus 로고
    • Cross-protective efficacy of a prophylactic Leishmania donovani DNA vaccine against visceral and cutaneous murine leishmaniasis
    • Aguilar-Be I, da Silva Zardo R, Paraguai de Souza E, et al. Cross-protective efficacy of a prophylactic Leishmania donovani DNA vaccine against visceral and cutaneous murine leishmaniasis. Infect Immun 2005;73:812-9
    • (2005) Infect Immun , vol.73 , pp. 812-819
    • Aguilar-Be, I.1    da Silva Zardo, R.2    Paraguai de Souza, E.3
  • 78
    • 33746786089 scopus 로고    scopus 로고
    • Immunotherapy against visceral leishmaniasis with the nucleoside hydrolase-DNA vaccine of Leishmania donovani
    • Gamboa-León R, Paraguai de Souza E, Borja-Cabrera GP, et al. Immunotherapy against visceral leishmaniasis with the nucleoside hydrolase-DNA vaccine of Leishmania donovani. Vaccine 2006;24:4863-73
    • (2006) Vaccine , vol.24 , pp. 4863-4873
    • Gamboa-León, R.1    Paraguai de Souza, E.2    Borja-Cabrera, G.P.3
  • 79
    • 0032560547 scopus 로고    scopus 로고
    • Boosting with recombinant vaccinia increases immunogenicity and protective efficacy of malaria DNA vaccine
    • Sedegah M, Jones TR, Kaur M, et al. Boosting with recombinant vaccinia increases immunogenicity and protective efficacy of malaria DNA vaccine. Proc Natl Acad Sci USA 1998;95:7648-53
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 7648-7653
    • Sedegah, M.1    Jones, T.R.2    Kaur, M.3
  • 80
    • 0037081386 scopus 로고    scopus 로고
    • A heterologous prime-boost regime using DNA and recombinant vaccinia virus expressing the Leishmania infantum P36/LACK antigen protects BALB/c mice from cutaneous leishmaniasis
    • Gonzalo RM, del Real G, Rodriguez JR, et al. A heterologous prime-boost regime using DNA and recombinant vaccinia virus expressing the Leishmania infantum P36/LACK antigen protects BALB/c mice from cutaneous leishmaniasis. Vaccine 2002;20:1226-31
    • (2002) Vaccine , vol.20 , pp. 1226-1231
    • Gonzalo, R.M.1    del Real, G.2    Rodriguez, J.R.3
  • 81
    • 0037295526 scopus 로고    scopus 로고
    • The combination of DNA vectors expressing IL-12 + IL-18 elicits high protective immune response against cutaneous leishmaniasis after priming with DNA-p36/LACK and the cytokines, followed by a booster with a vaccinia virus recombinant expressing p36/LACK
    • Tapia E, Pérez-Jiménez E, López-Fuertes L, et al. The combination of DNA vectors expressing IL-12 + IL-18 elicits high protective immune response against cutaneous leishmaniasis after priming with DNA-p36/LACK and the cytokines, followed by a booster with a vaccinia virus recombinant expressing p36/LACK. Microbes Infect 2003;5:73-84
    • (2003) Microbes Infect , vol.5 , pp. 73-84
    • Tapia, E.1    Pérez-Jiménez, E.2    López-Fuertes, L.3
  • 82
    • 0037726800 scopus 로고    scopus 로고
    • Protection in dogs against visceral leishmaniasis caused by Leishmania infantum is achieved by immunization with a heterologous prime-boost regime using DNA and vaccinia recombinant vectors expressing LACK
    • Ramniro MJ, Zárate JJ, Hanke T, et al. Protection in dogs against visceral leishmaniasis caused by Leishmania infantum is achieved by immunization with a heterologous prime-boost regime using DNA and vaccinia recombinant vectors expressing LACK. Vaccine 2003;21:2474-84
    • (2003) Vaccine , vol.21 , pp. 2474-2484
    • Ramniro, M.J.1    Zárate, J.J.2    Hanke, T.3
  • 83
    • 33646072495 scopus 로고    scopus 로고
    • MVA-LACK as a safe and efficient vector for vaccination against leishmaniasis
    • Pérez-Jiménez E, Kochan G, Gherardi MM, Esteban M. MVA-LACK as a safe and efficient vector for vaccination against leishmaniasis. Microbes Infect 2006;8:810-22
    • (2006) Microbes Infect , vol.8 , pp. 810-822
    • Pérez-Jiménez, E.1    Kochan, G.2    Gherardi, M.M.3    Esteban, M.4
  • 84
    • 23344439229 scopus 로고    scopus 로고
    • Heterologous prime-boost vaccination with the LACK antigen protects against murine visceral leishmaniasis
    • Dondji B, Pérez-Jimenez E, Goldsmith-Pestana K, et al. Heterologous prime-boost vaccination with the LACK antigen protects against murine visceral leishmaniasis. Infect Immun 2005;73:5286-9
    • (2005) Infect Immun , vol.73 , pp. 5286-5289
    • Dondji, B.1    Pérez-Jimenez, E.2    Goldsmith-Pestana, K.3
  • 85
    • 37549005549 scopus 로고    scopus 로고
    • Heterologous prime-boost vaccination with a non-replicative vaccinia recombinant vector expressing LACK confers protection against canine visceral leishmaniasis with a predominant Th1-specific immune response
    • Ramos I, Alonso A, Marcen JM, et al. Heterologous prime-boost vaccination with a non-replicative vaccinia recombinant vector expressing LACK confers protection against canine visceral leishmaniasis with a predominant Th1-specific immune response. Vaccine 2008;26:333-44
    • (2008) Vaccine , vol.26 , pp. 333-344
    • Ramos, I.1    Alonso, A.2    Marcen, J.M.3
  • 86
    • 3342965738 scopus 로고    scopus 로고
    • DNA-Salmonella enterica serovar Typhimurium primer-booster vaccination biases towards T helper 1 responses and enhances protection against Leishmania major infection in mice
    • Lange UG, Mastroeni P, Blackwell JM, Stober CB. DNA-Salmonella enterica serovar Typhimurium primer-booster vaccination biases towards T helper 1 responses and enhances protection against Leishmania major infection in mice. Infect Immun 2004;72:4924-8
    • (2004) Infect Immun , vol.72 , pp. 4924-4928
    • Lange, U.G.1    Mastroeni, P.2    Blackwell, J.M.3    Stober, C.B.4
  • 87
    • 32844459122 scopus 로고    scopus 로고
    • Prime-boost vaccination using cysteine proteinases type I and II of Leishmania infantum confers protective immunity in murine visceral leishmaniasis
    • Rafati S, Zahedifard F, Nazgouee F. Prime-boost vaccination using cysteine proteinases type I and II of Leishmania infantum confers protective immunity in murine visceral leishmaniasis. Vaccine 2006;24:2169-75
    • (2006) Vaccine , vol.24 , pp. 2169-2175
    • Rafati, S.1    Zahedifard, F.2    Nazgouee, F.3
  • 88
    • 21044441505 scopus 로고    scopus 로고
    • Protective vaccination against experimental canine visceral leishmaniasis using a combination of DNA and protein immunization with cysteine proteinases type I and II of L. infantum
    • Rafati S, Nakhaee A, Taheri T, et al. Protective vaccination against experimental canine visceral leishmaniasis using a combination of DNA and protein immunization with cysteine proteinases type I and II of L. infantum. Vaccine 2005;23:3716-25
    • (2005) Vaccine , vol.23 , pp. 3716-3725
    • Rafati, S.1    Nakhaee, A.2    Taheri, T.3
  • 89
    • 20444402610 scopus 로고    scopus 로고
    • A heterologous prime-boost vaccination regimen using ORFF DNA and recombinant ORFF protein confers protective immunity against experimental visceral leishmaniasis
    • Tewary P, Jain M, Sahani MH, et al. A heterologous prime-boost vaccination regimen using ORFF DNA and recombinant ORFF protein confers protective immunity against experimental visceral leishmaniasis. J Infect Dis 2005;191:2130-7
    • (2005) J Infect Dis , vol.191 , pp. 2130-2137
    • Tewary, P.1    Jain, M.2    Sahani, M.H.3
  • 90
    • 0031739890 scopus 로고    scopus 로고
    • Antigen-pulsed epidermal Langerhans cells protect susceptible mice from infection with the intracellular parasite Leishmania major
    • Flohé SB, Bauer C, Flohé S, Moll H. Antigen-pulsed epidermal Langerhans cells protect susceptible mice from infection with the intracellular parasite Leishmania major. Eur J Immunol 1998; 28:3800-11
    • (1998) Eur J Immunol , vol.28 , pp. 3800-3811
    • Flohé, S.B.1    Bauer, C.2    Flohé, S.3    Moll, H.4
  • 91
    • 0033214404 scopus 로고    scopus 로고
    • Dendritic cell (DC)-based anti-infective strategies: DCs engineered to secrete IL-12 are a potent vaccine in a murine model of an intracellular infection
    • Ahuja SS, Reddick RL, Sato N, et al. Dendritic cell (DC)-based anti-infective strategies: DCs engineered to secrete IL-12 are a potent vaccine in a murine model of an intracellular infection. J Immunol 1999;163:3890-7
    • (1999) J Immunol , vol.163 , pp. 3890-3897
    • Ahuja, S.S.1    Reddick, R.L.2    Sato, N.3
  • 92
    • 0347297137 scopus 로고    scopus 로고
    • Dendritic cell (DC)-based protection against an intracellular pathogen is dependent upon DC-derived IL-12 and can be induced by molecularly defined antigens
    • Berberich C, Ramírez-Pineda JR, Hambrecht C, et al. Dendritic cell (DC)-based protection against an intracellular pathogen is dependent upon DC-derived IL-12 and can be induced by molecularly defined antigens. J Immunol 2003;170:3171-9
    • (2003) J Immunol , vol.170 , pp. 3171-3179
    • Berberich, C.1    Ramírez-Pineda, J.R.2    Hambrecht, C.3
  • 93
    • 2442473115 scopus 로고    scopus 로고
    • Dendritic cells (DC) activated by CpG DNA ex vivo are potent inducers of host resistance to an intracellular pathogen that is independent of IL-12 derived from the immunizing DC
    • Ramírez-Pineda JR, Fröhlich A, Berberich C, Moll H. Dendritic cells (DC) activated by CpG DNA ex vivo are potent inducers of host resistance to an intracellular pathogen that is independent of IL-12 derived from the immunizing DC. J Immunol 2004;172:6281-9
    • (2004) J Immunol , vol.172 , pp. 6281-6289
    • Ramírez-Pineda, J.R.1    Fröhlich, A.2    Berberich, C.3    Moll, H.4
  • 94
    • 34247490635 scopus 로고    scopus 로고
    • Adoptive transfer of dendritic cells pulsed with Leishmania infantum nucleosomal histones confers protection against cutaneous leishmaniasis in BALB/c mice
    • Carrión J, Nieto A, Soto M, Alonso C. Adoptive transfer of dendritic cells pulsed with Leishmania infantum nucleosomal histones confers protection against cutaneous leishmaniasis in BALB/c mice. Microbes Infect 2007;9:735-43
    • (2007) Microbes Infect , vol.9 , pp. 735-743
    • Carrión, J.1    Nieto, A.2    Soto, M.3    Alonso, C.4
  • 95
    • 0016328268 scopus 로고
    • Liposomes as immunological adjuvants
    • Allison AG, Gregoriadis G. Liposomes as immunological adjuvants. Nature 1974;252:252
    • (1974) Nature , vol.252 , pp. 252
    • Allison, A.G.1    Gregoriadis, G.2
  • 96
    • 0024309571 scopus 로고
    • Vaccination against murine cutaneous leishmaniasis by using Leishmania major antigen/liposomes. Optimization and assessment of the requirement for intravenous immunization
    • Kahl LP, Scott CA, Lelchuk R, et al. Vaccination against murine cutaneous leishmaniasis by using Leishmania major antigen/liposomes. Optimization and assessment of the requirement for intravenous immunization. J Immunol 1989;142:4441-9
    • (1989) J Immunol , vol.142 , pp. 4441-4449
    • Kahl, L.P.1    Scott, C.A.2    Lelchuk, R.3
  • 97
    • 0023886330 scopus 로고
    • Effective immunization against cutaneous leishmaniasis with defined membrane antigens reconstituted into liposomes
    • Russell DG, Alexander J. Effective immunization against cutaneous leishmaniasis with defined membrane antigens reconstituted into liposomes. J Immunol 1988;140:1274-9
    • (1988) J Immunol , vol.140 , pp. 1274-1279
    • Russell, D.G.1    Alexander, J.2
  • 98
    • 19944385594 scopus 로고    scopus 로고
    • Influence of phospholipid composition on the adjuvanticity and protective efficacy of liposome-encapsulated Leishmania donovani antigens
    • Mazumdar T, Anam K, Ali N. Influence of phospholipid composition on the adjuvanticity and protective efficacy of liposome-encapsulated Leishmania donovani antigens. J Parasitol 2005;91:269-74
    • (2005) J Parasitol , vol.91 , pp. 269-274
    • Mazumdar, T.1    Anam, K.2    Ali, N.3
  • 99
    • 1542330963 scopus 로고    scopus 로고
    • A mixed Th1/Th2 response elicited by a liposomal formulation of Leishmania vaccine instructs Th1 responses and resistance to Leishmania donovani in susceptible BALB/c mice
    • Mazumdar T, Anam K, Ali N. A mixed Th1/Th2 response elicited by a liposomal formulation of Leishmania vaccine instructs Th1 responses and resistance to Leishmania donovani in susceptible BALB/c mice. Vaccine 2004;22:1162-71
    • (2004) Vaccine , vol.22 , pp. 1162-1171
    • Mazumdar, T.1    Anam, K.2    Ali, N.3
  • 100
    • 32544433906 scopus 로고    scopus 로고
    • + T-cell immune response and protect hamsters against visceral leishmaniasis
    • + T-cell immune response and protect hamsters against visceral leishmaniasis. Vaccine 2006;24:1800-10
    • (2006) Vaccine , vol.24 , pp. 1800-1810
    • Sharma, S.K.1    Dube, A.2    Nadeem, A.3
  • 101
    • 0030976397 scopus 로고    scopus 로고
    • Adjuvanticity and protective immunity elicited by Leishmania donovani antigens encapsulated in positively charged liposomes
    • Afrin F, Ali N. Adjuvanticity and protective immunity elicited by Leishmania donovani antigens encapsulated in positively charged liposomes. Infect Immun 1997;65:2371-7
    • (1997) Infect Immun , vol.65 , pp. 2371-2377
    • Afrin, F.1    Ali, N.2
  • 102
    • 0033842983 scopus 로고    scopus 로고
    • Induction of partial protection against Leishmania donovani by promastigote antigens in negatively charged liposomes
    • Afrin F, Anam K, Ali N. Induction of partial protection against Leishmania donovani by promastigote antigens in negatively charged liposomes. J Parasitol 2000;86:730-5
    • (2000) J Parasitol , vol.86 , pp. 730-735
    • Afrin, F.1    Anam, K.2    Ali, N.3
  • 103
    • 0030970746 scopus 로고    scopus 로고
    • Protection of mice against visceral leishmaniasis by immunization with promastigote antigen incorporated in liposomes
    • Ali N, Afrin F. Protection of mice against visceral leishmaniasis by immunization with promastigote antigen incorporated in liposomes. J Parasitol 1997;83:70-5
    • (1997) J Parasitol , vol.83 , pp. 70-75
    • Ali, N.1    Afrin, F.2
  • 104
    • 34547578743 scopus 로고    scopus 로고
    • Leishmanial antigens in liposomes promote protective immunity and provide immunotherapy against visceral leishmaniasis via polariazed Th1 response
    • Bhowmick S, Ravindran R, Ali N. Leishmanial antigens in liposomes promote protective immunity and provide immunotherapy against visceral leishmaniasis via polariazed Th1 response. Vaccine 2007;25:6544-56
    • (2007) Vaccine , vol.25 , pp. 6544-6556
    • Bhowmick, S.1    Ravindran, R.2    Ali, N.3
  • 105
    • 40749103367 scopus 로고    scopus 로고
    • gp63 in stable cationic liposomes confers sustained vaccine immunity to susceptible BALB/c mice infected with Leishmania donovani
    • Bhowmick S, Ravindran R, Ali N. gp63 in stable cationic liposomes confers sustained vaccine immunity to susceptible BALB/c mice infected with Leishmania donovani. Infect Immun 2008;76:1003-15
    • (2008) Infect Immun , vol.76 , pp. 1003-1015
    • Bhowmick, S.1    Ravindran, R.2    Ali, N.3
  • 106
    • 0343938832 scopus 로고    scopus 로고
    • Delivery of lipids and liposomal proteins to the cytoplasm and Golgi of antigen-presenting cells
    • Rao M, Alving CR. Delivery of lipids and liposomal proteins to the cytoplasm and Golgi of antigen-presenting cells. Adv Drug Deliv Rev 2000;41:171-88
    • (2000) Adv Drug Deliv Rev , vol.41 , pp. 171-188
    • Rao, M.1    Alving, C.R.2
  • 107
    • 2342625401 scopus 로고    scopus 로고
    • Interaction of dendritic cells with antigen-containing liposomes: Effect of bilayer composition
    • Foged C, Arigita C, Sundblad A, et al. Interaction of dendritic cells with antigen-containing liposomes: effect of bilayer composition. Vaccine 2004;22:1903-13
    • (2004) Vaccine , vol.22 , pp. 1903-1913
    • Foged, C.1    Arigita, C.2    Sundblad, A.3
  • 108
    • 0035575703 scopus 로고    scopus 로고
    • Efficient delivery of Antennapedia homeodomain fused to CTL epitope with liposomes into dendritic cells results in the activation of CD8+ T cells
    • Chikh GG, Kong S, Bally MB, et al. Efficient delivery of Antennapedia homeodomain fused to CTL epitope with liposomes into dendritic cells results in the activation of CD8+ T cells. J Immunol 2001;167:6462-70
    • (2001) J Immunol , vol.167 , pp. 6462-6470
    • Chikh, G.G.1    Kong, S.2    Bally, M.B.3
  • 109
    • 0032816878 scopus 로고    scopus 로고
    • Nakanishi T, Kunisawa J, Hayashi A, et al. Positively charged liposome functions as an efficient immunoadjuvant in inducing cell-mediated immune response to soluble proteins. J Control Release 1999;61:233-40
    • Nakanishi T, Kunisawa J, Hayashi A, et al. Positively charged liposome functions as an efficient immunoadjuvant in inducing cell-mediated immune response to soluble proteins. J Control Release 1999;61:233-40
  • 110
    • 0034882516 scopus 로고    scopus 로고
    • On the mechanism whereby cationic lipids promote intracellular delivery of polynucleic acids
    • Hafez IM, Maurer N, Cullis PR. On the mechanism whereby cationic lipids promote intracellular delivery of polynucleic acids. Gene Ther 2001;8:1188-96
    • (2001) Gene Ther , vol.8 , pp. 1188-1196
    • Hafez, I.M.1    Maurer, N.2    Cullis, P.R.3
  • 112
    • 36549050775 scopus 로고    scopus 로고
    • Non-coding pDNA bearing immunostimulatory sequences co-entrapped with leishmanial antigens in cationic liposomes elicits almost complete protection against experimental visceral leishmaniasis in BALB/c mice
    • Mazumder S, Ravindran R, Banerjee A, Ali N. Non-coding pDNA bearing immunostimulatory sequences co-entrapped with leishmanial antigens in cationic liposomes elicits almost complete protection against experimental visceral leishmaniasis in BALB/c mice. Vaccine 2007;25:8771-81
    • (2007) Vaccine , vol.25 , pp. 8771-8781
    • Mazumder, S.1    Ravindran, R.2    Banerjee, A.3    Ali, N.4
  • 113
    • 34447513762 scopus 로고    scopus 로고
    • The role of CpG ODN in enhancement of immune response and protection in BALB/c mice immunized with recombinant major surface glycoprotein of Leishmania (rgp63) encapsulated in cationic liposome
    • Jaafari MR, Badiee A, Khamesipour A, et al. The role of CpG ODN in enhancement of immune response and protection in BALB/c mice immunized with recombinant major surface glycoprotein of Leishmania (rgp63) encapsulated in cationic liposome. Vaccine 2007;25:6107-17
    • (2007) Vaccine , vol.25 , pp. 6107-6117
    • Jaafari, M.R.1    Badiee, A.2    Khamesipour, A.3
  • 114
    • 36348945135 scopus 로고    scopus 로고
    • Therapeutic applications of synthetic CpG oligodeoxynucleotides as TLR9 agonists for immune modulation
    • Jurk M, Vollmer J. Therapeutic applications of synthetic CpG oligodeoxynucleotides as TLR9 agonists for immune modulation. Biodrugs 2007;21:387-401
    • (2007) Biodrugs , vol.21 , pp. 387-401
    • Jurk, M.1    Vollmer, J.2
  • 116
    • 48449092989 scopus 로고    scopus 로고
    • Immunization with Toll-like receptor 7/8 agonist vaccine adjuvants increases protective immunity against Leishmania major in BALB/c mice
    • In press
    • Zhang WW, Matlashewski G. Immunization with Toll-like receptor 7/8 agonist vaccine adjuvants increases protective immunity against Leishmania major in BALB/c mice. Infect Immun 2008; In press
    • (2008) Infect Immun
    • Zhang, W.W.1    Matlashewski, G.2
  • 117
    • 36749099986 scopus 로고    scopus 로고
    • A needle-free approach for topical immunization: Antigen delivery via vesicular carrier system(s)
    • Mahor S, Gupta PN, Rawat A, Vyas SP. A needle-free approach for topical immunization: antigen delivery via vesicular carrier system(s). Curr Med Chem 2007;14:2898-910
    • (2007) Curr Med Chem , vol.14 , pp. 2898-2910
    • Mahor, S.1    Gupta, P.N.2    Rawat, A.3    Vyas, S.P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.