DNA vaccines and adjuvants

Immunological Reviews

Volumn 199, Issue , 2004, Pages 5-8

  Stevenson, Freda K ^a  

^a UNIVERSITY HOSPITAL SOUTHAMPTON NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DNA VACCINE; MALARIA VACCINE;

ANTIGEN EXPRESSION; BIOLOGICAL WARFARE; CANCER; GENE EXPRESSION; GENE GUN; GENE TARGETING; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; IMMUNE RESPONSE; IMMUNE SYSTEM; IMMUNITY; IMMUNOGENICITY; INFECTION; MALARIA; NONHUMAN; PRIORITY JOURNAL; REVIEW; VACCINATION;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; HUMANS; INFECTION; VACCINES, DNA;

EID: 2942557170     PISSN: 01052896     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0105-2896.2004.00146.x     Document Type: Review

References (12)

1. Wolff JA, et al. Direct gene transfer into mouse muscle in vivo. Science 1990;247:1465-1468.
2. Ulmer JB, et al. Heterologous protection against influenza by injection of DNA encoding a viral protein. Science 1993;259:1745-1749.
3. Tang DC, DeVit M, Johnston SA. Genetic immunization is a simple method for eliciting an immune response. Nature 1992;356:152-154.
4. Krieg AM. CpG motifs in bacterial DNA and their immune effects. Annu Rev Immunol 2002;20:709-760.
5. Hemmi H, et al. A Toll-like receptor recognizes bacterial DNA. Nature 2000;408:740-745.
6. Spies B, et al. Vaccination with plasmid DNA activates dendritic cells via toll-like receptor 9 (TLR9) but functions in TLR9-deficient mice. J Immunol 2003;171:5908-5912.
7. Doe B, Selby M, Barnett S, Baenziger J, Walker CM. Induction of cytotoxic T lymphocytes by intramuscular immunization with plasmid DNA is facilitated by bone marrow-derived cells. Proc Natl Acad Sci USA 1996;93:8578-8583.
8. Corr M, Lee DJ, Carson DA, Tighe H. Gene vaccination with naked plasmid DNA: mechanism of CTL priming. J Exp Med 1996;184:1555-1560.
9. Torres CA, Iwasaki A, Barber BH, Robinson HL. Differential dependence on target site tissue for gene gun and intramuscular DNA immunizations. J Immunol 1997;158:4529-4532.
10. Houde M, et al. Phagosomes are competent organelles for antigen cross-presentation. Nature 2003;425:402-406.
11. Condon C, Watkins SC, Celluzzi CM, Thompson K, LD. DNA-based immunization by in vivo transfection of dendritic cells. Nat Med 1996;2:1122-1128.
12. Cho JH, Youn JW, Sung YC. Cross-priming as a predominant mechanism for inducing CD8(+) T cell responses in gene gun DNA immunization. J Immunol 2001;167:5549-5557.