Failure of a multi-subunit recombinant leishmanial vaccine (MML) to protect dogs from Leishmania infantum infection and to prevent disease progression in infected animals

Vaccine

Volumn 23, Issue 45, 2005, Pages 5245-5251

  Gradoni, L ^a   Foglia Manzillo, V ^b   Pagano, A ^b   Piantedosi, D ^b   De Luna, R ^b   Gramiccia, M ^a   Scalone, A ^a   Di Muccio, T ^a   Oliva, G ^b  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Canine leishmaniasis; Leishmania; Recombinant polyprotein; Vaccine

Indexed keywords

ADJUPRIME ADJUVANT; IMMUNOLOGICAL ADJUVANT; LEISH 111F ANTIGEN; LEISHMANIA VACCINE; PARASITE ANTIGEN; PHOSPHORYL LIPID A; RECOMBINANT VACCINE; SUBUNIT VACCINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DISEASE TRANSMISSION; DOG; DRUG EFFICACY; FEMALE; ITALY; LEISHMANIA INFANTUM; LEISHMANIASIS; LYMPHOCYTE PROLIFERATION; MALE; MICROSCOPY; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PSYCHODIDAE; SEROLOGY; VACCINATION;

ANIMALS; ANTIGENS, PROTOZOAN; CELL PROLIFERATION; DISEASE PROGRESSION; DISEASE RESERVOIRS; DNA, COMPLEMENTARY; DOG DISEASES; DOGS; ENZYME-LINKED IMMUNOSORBENT ASSAY; IMMUNIZATION, SECONDARY; IMMUNOGLOBULIN G; ITALY; LEISHMANIA INFANTUM; LEISHMANIASIS, VISCERAL; LYMPHOCYTES; PROTOZOAN VACCINES; PSYCHODIDAE; RECOMBINANT PROTEINS; TICKS; VACCINATION;

EID: 26644448719     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2005.07.001     Document Type: Article

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