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Volumn 170, Issue 6, 2003, Pages 3171-3179

Dendritic cell (DC)-based protection against an intracellular pathogen is dependent upon DC-derived IL-12 and can be induced by molecularly defined antigens

Author keywords

[No Author keywords available]

Indexed keywords

ELONGATION FACTOR; GLYCOPROTEIN; GLYCOPROTEIN GP 63; INITIATION FACTOR; INITIATION FACTOR 4A; INTERLEUKIN 12; MEMBRANE ANTIGEN; MEMBRANE PROTEIN; PARASITE ANTIGEN; PROTEIN KINASE C; UNCLASSIFIED DRUG;

EID: 0347297137     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.170.6.3171     Document Type: Article
Times cited : (106)

References (53)
  • 1
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau, J., and R. M. Steinman. 1998. Dendritic cells and the control of immunity. Nature 392:245.
    • (1998) Nature , vol.392 , pp. 245
    • Banchereau, J.1    Steinman, R.M.2
  • 2
    • 0034995061 scopus 로고    scopus 로고
    • Dendritic cells as sensors of infection
    • Reis e Sousa, C. 2001. Dendritic cells as sensors of infection. Immunity 14:495.
    • (2001) Immunity , vol.14 , pp. 495
    • Reis e Sousa, C.1
  • 4
    • 0034278725 scopus 로고    scopus 로고
    • Dendritic cell regulation of Th1-Th2 development
    • Moser, M., and K. M. Murphy. 2000. Dendritic cell regulation of Th1-Th2 development. Nat. Immunol. 1:199.
    • (2000) Nat. Immunol. , vol.1 , pp. 199
    • Moser, M.1    Murphy, K.M.2
  • 5
    • 0034305809 scopus 로고    scopus 로고
    • Kinetics of dendritic cell activation: Impact on priming of Th1, Th2 and nonpolarized T cells
    • Langenkamp, A., M. Messi, A. Lanzavecchia, and F. Sallusto. 2000. Kinetics of dendritic cell activation: impact on priming of Th1, Th2 and nonpolarized T cells. Nat. Immunol. 1:311.
    • (2000) Nat. Immunol. , vol.1 , pp. 311
    • Langenkamp, A.1    Messi, M.2    Lanzavecchia, A.3    Sallusto, F.4
  • 7
    • 0000060327 scopus 로고    scopus 로고
    • In vivo microbial stimulation induces rapid CD40 ligand-independent production of interleukin 12 by dendritic cells and their redistribution to T cell areas
    • Reis e Sousa, C., S. Hieny, T. Scharton-Kersten, D. Jankovic, H. Charest, R. Germain, and A. Sher. 1997. In vivo microbial stimulation induces rapid CD40 ligand-independent production of interleukin 12 by dendritic cells and their redistribution to T cell areas. J. Exp. Med. 186:1819.
    • (1997) J. Exp. Med. , vol.186 , pp. 1819
    • Reis e Sousa, C.1    Hieny, S.2    Scharton-Kersten, T.3    Jankovic, D.4    Charest, H.5    Germain, R.6    Sher, A.7
  • 8
    • 0030058647 scopus 로고    scopus 로고
    • Therapy of murine tumors with tumor peptide-pulsed dendritic cells: Dependence on T cells, B7 costimulation, and T helper cell 1-associated cytokines
    • Zitvogel, L., J. L. Mayordomo, T. Tjandrawan, A. B. DeLeo, M. R. Clarke, M. T. Lotze, and W. J. Storkus. 1996. Therapy of murine tumors with tumor peptide-pulsed dendritic cells: dependence on T cells, B7 costimulation, and T helper cell 1-associated cytokines. J. Exp. Med. 183:87.
    • (1996) J. Exp. Med. , vol.183 , pp. 87
    • Zitvogel, L.1    Mayordomo, J.L.2    Tjandrawan, T.3    DeLeo, A.B.4    Clarke, M.R.5    Lotze, M.T.6    Storkus, W.J.7
  • 10
    • 0032036433 scopus 로고    scopus 로고
    • Physical interaction between dendritic cells and tumor cells results in an immunogen that induces protective and therapeutic tumor rejection
    • Celluzzi, C. M., and L. D. Falo, Jr. 1998. Physical interaction between dendritic cells and tumor cells results in an immunogen that induces protective and therapeutic tumor rejection. J. Immunol. 160:3081.
    • (1998) J. Immunol. , vol.160 , pp. 3081
    • Celluzzi, C.M.1    Falo L.D., Jr.2
  • 13
    • 0033405438 scopus 로고    scopus 로고
    • Vaccination with Mage-3A1 peptide-pulsed mature, monocyte-derived dendritic cells expands specific cytotoxic T cells and induces regression of some metastases in advanced stage IV melanoma
    • Thumer, B., I. Haendle, C. Röder, D. Dieckmann, P. Keikavoussi, H. Jonuleit, A. Bender, C. Maczek, D. Schreiner, P. von den Driesch, et al. 1999. Vaccination with Mage-3A1 peptide-pulsed mature, monocyte-derived dendritic cells expands specific cytotoxic T cells and induces regression of some metastases in advanced stage IV melanoma. J. Exp. Med. 190:1669.
    • (1999) J. Exp. Med. , vol.190 , pp. 1669
    • Thumer, B.1    Haendle, I.2    Röder, C.3    Dieckmann, D.4    Keikavoussi, P.5    Jonuleit, H.6    Bender, A.7    Maczek, C.8    Schreiner, D.9    Von den Driesch, P.10
  • 14
    • 0034756243 scopus 로고    scopus 로고
    • Dendritic cells as vectors for vaccination against infectious diseases
    • Moll, H., and C. Berberich. 2001. Dendritic cells as vectors for vaccination against infectious diseases. Int. J. Med. Microbiol. 291:323.
    • (2001) Int. J. Med. Microbiol. , vol.291 , pp. 323
    • Moll, H.1    Berberich, C.2
  • 15
    • 0028933795 scopus 로고
    • The regulation of immunity to Leishmania major
    • Reiner S. L., and R. M. Locksley. 1995. The regulation of immunity to Leishmania major. Annu. Rev. Immunol. 13:151.
    • (1995) Annu. Rev. Immunol. , vol.13 , pp. 151
    • Reiner, S.L.1    Locksley, R.M.2
  • 16
    • 43949166190 scopus 로고
    • Epidermal Langerhans cells are critical for immunoregulation of cutaneous leishmaniasis
    • Moll, H. 1993. Epidermal Langerhans cells are critical for immunoregulation of cutaneous leishmaniasis. Immunol. Today 14:383.
    • (1993) Immunol. Today , vol.14 , pp. 383
    • Moll, H.1
  • 17
    • 0028949382 scopus 로고
    • Dendritic cells in Leishmania major-immune mice harbor persistent parasites and mediate an antigen-specific T cell immune response
    • Moll, H., S. Flohé, and M. Röllinghoff. 1995. Dendritic cells in Leishmania major-immune mice harbor persistent parasites and mediate an antigen-specific T cell immune response. Eur. J. Immunol. 25:693.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 693
    • Moll, H.1    Flohé, S.2    Röllinghoff, M.3
  • 18
    • 0031889474 scopus 로고    scopus 로고
    • Dendritic cells, but not macrophages, produce IL-12 immediately following Leishmania donovani infection
    • Gorak, P. M., C. R. Engwerda, and P. M. Kaye. 1998. Dendritic cells, but not macrophages, produce IL-12 immediately following Leishmania donovani infection. Eur. J. Immunol. 28:687.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 687
    • Gorak, P.M.1    Engwerda, C.R.2    Kaye, P.M.3
  • 19
    • 0032547859 scopus 로고    scopus 로고
    • Uptake of Leishmania major amastigotes results in activation and interleukin 12 release from murine skin-derived dendritic cells: Implications for the initiation of anti-Leishmania immunity
    • von Stebut, E., Y. Belkaid, T. Jakob, D. L. Sacks, and M. C. Udey. 1998. Uptake of Leishmania major amastigotes results in activation and interleukin 12 release from murine skin-derived dendritic cells: implications for the initiation of anti-Leishmania immunity. J. Exp. Med. 188:1547.
    • (1998) J. Exp. Med. , vol.188 , pp. 1547
    • Von Stebut, E.1    Belkaid, Y.2    Jakob, T.3    Sacks, D.L.4    Udey, M.C.5
  • 20
    • 0031739890 scopus 로고    scopus 로고
    • Antigen-pulsed epidermal Langerhans cells protect susceptible mice from infection with the intracellular parasite Leishmania major
    • Flohé, S. B., C. Bauer, S. Flohé, and H. Moll. 1998. Antigen-pulsed epidermal Langerhans cells protect susceptible mice from infection with the intracellular parasite Leishmania major. Eur. J. Immunol. 28:3800.
    • (1998) Eur. J. Immunol. , vol.28 , pp. 3800
    • Flohé, S.B.1    Bauer, C.2    Flohé, S.3    Moll, H.4
  • 21
    • 0029849205 scopus 로고    scopus 로고
    • Resistance to Leishmania major induced by tolerance to a single antigen
    • Julia, V., M. Rassoulzadegan, and N. Glaichenhaus. 1996. Resistance to Leishmania major induced by tolerance to a single antigen. Science 274:421.
    • (1996) Science , vol.274 , pp. 421
    • Julia, V.1    Rassoulzadegan, M.2    Glaichenhaus, N.3
  • 23
    • 0030822043 scopus 로고    scopus 로고
    • Vaccination with DNA encoding the immunodominant LACK parasite antigen confers protective immunity to mice infected with Leishmania major
    • Gurunathan, S., D. L. Sacks, D. R. Brown, S. L. Reiner, H. Charest, N. Glaichenhaus, and R. A. Seder. 1997. Vaccination with DNA encoding the immunodominant LACK parasite antigen confers protective immunity to mice infected with Leishmania major. J. Exp. Med. 186:1137.
    • (1997) J. Exp. Med. , vol.186 , pp. 1137
    • Gurunathan, S.1    Sacks, D.L.2    Brown, D.R.3    Reiner, S.L.4    Charest, H.5    Glaichenhaus, N.6    Seder, R.A.7
  • 24
    • 0028929566 scopus 로고
    • A recombinant Leishmania antigen that stimulates human peripheral blood mononuclear cells to express a Th1-type cytokine profile and to produce interleukin 12
    • Skeiky, Y. A. W., J. A. Guderian, D. R. Benson, O. Bacelar, E. M. Carvalho, M. Kubin, R. Badaro, G. Trinchieri, and S. G. Reed. 1995. A recombinant Leishmania antigen that stimulates human peripheral blood mononuclear cells to express a Th1-type cytokine profile and to produce interleukin 12. J. Exp. Med. 181:1527.
    • (1995) J. Exp. Med. , vol.181 , pp. 1527
    • Skeiky, Y.A.W.1    Guderian, J.A.2    Benson, D.R.3    Bacelar, O.4    Carvalho, E.M.5    Kubin, M.6    Badaro, R.7    Trinchieri, G.8    Reed, S.G.9
  • 25
    • 0027141144 scopus 로고
    • Effective immunization against cutaneous leishmaniasis with recombinant bacille Calmette-Guérin expressing the Leishmania surface proteinase gp63
    • Connell, N. D., E. Medina-Acosta, W. R. McMaster, B. R. Bloom, and D. G. Russell. 1993. Effective immunization against cutaneous leishmaniasis with recombinant bacille Calmette-Guérin expressing the Leishmania surface proteinase gp63. Proc. Natl. Acad. Sci. USA 90:11473.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 11473
    • Connell, N.D.1    Medina-Acosta, E.2    McMaster, W.R.3    Bloom, B.R.4    Russell, D.G.5
  • 26
    • 0022652645 scopus 로고
    • The involvement of the major surface glycoprotein (gp63) of Leishmania promastigotes in attachment to macrophages
    • Russell, D. G., and H. Wilhelm. 1986. The involvement of the major surface glycoprotein (gp63) of Leishmania promastigotes in attachment to macrophages. J. Immunol. 136:2613.
    • (1986) J. Immunol. , vol.136 , pp. 2613
    • Russell, D.G.1    Wilhelm, H.2
  • 27
    • 0025172078 scopus 로고
    • Molecular cloning and characterization of the immunologically protective surface glycoprotein GP46/M-2 of Leishmania amazonensis
    • Lohman, K. L., P. J. Langer, and D. McMahon-Pratt. 1990. Molecular cloning and characterization of the immunologically protective surface glycoprotein GP46/M-2 of Leishmania amazonensis. Proc. Natl. Acad. Sci. USA 87:8393.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 8393
    • Lohman, K.L.1    Langer, P.J.2    McMahon-Pratt, D.3
  • 28
    • 0035851346 scopus 로고    scopus 로고
    • Attenuated Toxoplasma gondii ts-4 mutants engineered to express the Leishmania antigen KMP-11 elicit a specific immune response in BALB/c mice
    • Ramírez, J. R., K. Gilchrist, S. Robledo, J. C. Sepulveda, H. Moll, D. Soldati, and C. Berberich. 2001. Attenuated Toxoplasma gondii ts-4 mutants engineered to express the Leishmania antigen KMP-11 elicit a specific immune response in BALB/c mice. Vaccine 20:455.
    • (2001) Vaccine , vol.20 , pp. 455
    • Ramírez, J.R.1    Gilchrist, K.2    Robledo, S.3    Sepulveda, J.C.4    Moll, H.5    Soldati, D.6    Berberich, C.7
  • 29
    • 0030002111 scopus 로고    scopus 로고
    • Genetically resistant mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response
    • Mattner, F., J. Magram, J. Ferrante, P. Launois, K. Di Padova, R. Behin, M. K. Gately, J. A. Louis, and G. Alber. 1996. Genetically resistant mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response. Eur. J. Immunol. 26:1553.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 1553
    • Mattner, F.1    Magram, J.2    Ferrante, J.3    Launois, P.4    Di Padova, K.5    Behin, R.6    Gately, M.K.7    Louis, J.A.8    Alber, G.9
  • 32
    • 0030004213 scopus 로고    scopus 로고
    • Presentation of the protective parasite antigen LACK by Leishmania-infected macrophages
    • Prina, E., T. Lang, N. Glaichenhaus, and J. C. Antoine. 1996. Presentation of the protective parasite antigen LACK by Leishmania-infected macrophages. J. Immunol. 156:4318.
    • (1996) J. Immunol. , vol.156 , pp. 4318
    • Prina, E.1    Lang, T.2    Glaichenhaus, N.3    Antoine, J.C.4
  • 33
    • 0027472098 scopus 로고
    • Structurally distinct genes for the surface protease of Leishmania mexicana are developmentally regulated
    • Medina-Acosta, E., R. E. Karess, and D. G. Russell. 1993. Structurally distinct genes for the surface protease of Leishmania mexicana are developmentally regulated. Mol. Biochem. Parasitol. 57:31.
    • (1993) Mol. Biochem. Parasitol. , vol.57 , pp. 31
    • Medina-Acosta, E.1    Karess, R.E.2    Russell, D.G.3
  • 34
    • 0032518324 scopus 로고    scopus 로고
    • Cloning, sequencing, and expression of the PSA genes from Leishmania infantum
    • Jiménez-Ruiz, A., C. Boceta, P. Bonay, J. M. Requena, and C. Alonso. 1998. Cloning, sequencing, and expression of the PSA genes from Leishmania infantum. Eur. J. Biochem. 251:389.
    • (1998) Eur. J. Biochem. , vol.251 , pp. 389
    • Jiménez-Ruiz, A.1    Boceta, C.2    Bonay, P.3    Requena, J.M.4    Alonso, C.5
  • 35
    • 0031001121 scopus 로고    scopus 로고
    • Cloning of genes and expression and antigenicity analysis of the Leishmania infantum KMP-11 protein
    • Berberich, C., J. M. Requena, and C. Alonso. 1997. Cloning of genes and expression and antigenicity analysis of the Leishmania infantum KMP-11 protein. Exp. Parasitol. 85:105.
    • (1997) Exp. Parasitol. , vol.85 , pp. 105
    • Berberich, C.1    Requena, J.M.2    Alonso, C.3
  • 38
    • 0002750572 scopus 로고
    • Enrichment of epidermal Langerhans cells
    • G. Schuler, ed. CRC Press, Boca Raton
    • Schuler, G., and F. Koch. 1990. Enrichment of epidermal Langerhans cells. In Epidermal Langerhans Cells, G. Schuler, ed. CRC Press, Boca Raton, p. 139.
    • (1990) Epidermal Langerhans Cells , pp. 139
    • Schuler, G.1    Koch, F.2
  • 39
    • 0019468220 scopus 로고
    • Limiting dilution assays for the determination of immunocompetent cell frequencies. I. Data analysis
    • Taswell, C. 1981. Limiting dilution assays for the determination of immunocompetent cell frequencies. I. Data analysis. J. Immunol. 126:1614.
    • (1981) J. Immunol. , vol.126 , pp. 1614
    • Taswell, C.1
  • 40
    • 0033012030 scopus 로고    scopus 로고
    • An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow
    • Lutz, M. B., N. Kukutsch, A. L. J. Ogilvie, S. Rossner, F. Koch, N. Romani, and G. Schuler. 1999. An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow. J. Immunol. Methods 223:77.
    • (1999) J. Immunol. Methods , vol.223 , pp. 77
    • Lutz, M.B.1    Kukutsch, N.2    Ogilvie, A.L.J.3    Rossner, S.4    Koch, F.5    Romani, N.6    Schuler, G.7
  • 41
    • 0030695354 scopus 로고    scopus 로고
    • A Leishmania protein that modulates interleukin (IL)-12, IL-10 and tumor necrosis factor-α production and expression of B7-1 in human monocyte-derived antigen-presenting cells
    • Probst, P., Y. A. W. Skeiky, M. Steeves, A. Gervassi, K. H. Grabstein, and S. G. Reed. 1997. A Leishmania protein that modulates interleukin (IL)-12, IL-10 and tumor necrosis factor-α production and expression of B7-1 in human monocyte-derived antigen-presenting cells. Eur. J. Immunol. 27:2634.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 2634
    • Probst, P.1    Skeiky, Y.A.W.2    Steeves, M.3    Gervassi, A.4    Grabstein, K.H.5    Reed, S.G.6
  • 42
    • 0031569223 scopus 로고    scopus 로고
    • Bacterial lipopolysaccharide stimulates the production of cytokines and the expression of costimulatory molecules by human peripheral blood dendritic cells: Evidence for a soluble CD14-dependent pathway
    • Verhasselt, V., C. Buelens, F. Willems, D. De Groote, N. Haeffner-Cavaillon, and M. Goldman. 1997. Bacterial lipopolysaccharide stimulates the production of cytokines and the expression of costimulatory molecules by human peripheral blood dendritic cells: evidence for a soluble CD14-dependent pathway. J. Immunol. 158:2919.
    • (1997) J. Immunol. , vol.158 , pp. 2919
    • Verhasselt, V.1    Buelens, C.2    Willems, F.3    De Groote, D.4    Haeffner-Cavaillon, N.5    Goldman, M.6
  • 44
    • 0029077326 scopus 로고
    • IL-12 is required for natural killer cell activation and subsequent T helper 1 cell development in experimental leishmaniasis
    • Scharton-Kersten, T., L. C. Afonso, M. Wysocka, G. Trinchieri, and P. Scott. 1995. IL-12 is required for natural killer cell activation and subsequent T helper 1 cell development in experimental leishmaniasis. J. Immunol. 154:5320.
    • (1995) J. Immunol. , vol.154 , pp. 5320
    • Scharton-Kersten, T.1    Afonso, L.C.2    Wysocka, M.3    Trinchieri, G.4    Scott, P.5
  • 45
    • 0034533054 scopus 로고    scopus 로고
    • Leishmania major-infected murine Langerhans cell-like dendritic cells from susceptible mice release IL-12 after infection and vaccinate against experimental cutaneous leishmaniasis
    • von Stebut, E., Y. Belkaid, B. V. Nguyen, M., Cushing, D. L. Sacks, and M. C. Udey. 2000. Leishmania major-infected murine Langerhans cell-like dendritic cells from susceptible mice release IL-12 after infection and vaccinate against experimental cutaneous leishmaniasis. Eur. J. Immunol. 30:3498.
    • (2000) Eur. J. Immunol. , vol.30 , pp. 3498
    • Von Stebut, E.1    Belkaid, Y.2    Nguyen, B.V.3    Cushing, M.4    Sacks, D.L.5    Udey, M.C.6
  • 46
    • 0030859333 scopus 로고    scopus 로고
    • Borrelia burgdorferi-pulsed dendritic cells induce a protective immune response against tick-transmitted spirochetes
    • Mbow, M. L., N. Zeidner, N. Panella, R. G. Titus, and J. Piesman. 1997. Borrelia burgdorferi-pulsed dendritic cells induce a protective immune response against tick-transmitted spirochetes. Infect. Immun. 65:3386.
    • (1997) Infect. Immun. , vol.65 , pp. 3386
    • Mbow, M.L.1    Zeidner, N.2    Panella, N.3    Titus, R.G.4    Piesman, J.5
  • 47
    • 0032494186 scopus 로고    scopus 로고
    • Vaccination against chlamydial genital tract infection after immunization with dendritic cells pulsed ex vivo with nonviable Chlamydia
    • Su, H., R. Messer, W. Whitmire, E. Fischer, J. C. Portis, and H. D. Caldwell. 1998. Vaccination against chlamydial genital tract infection after immunization with dendritic cells pulsed ex vivo with nonviable Chlamydia. J. Exp. Med. 188:809.
    • (1998) J. Exp. Med. , vol.188 , pp. 809
    • Su, H.1    Messer, R.2    Whitmire, W.3    Fischer, E.4    Portis, J.C.5    Caldwell, H.D.6
  • 49
    • 0027248719 scopus 로고
    • Langerhans cells transport Leishmania major from the infected skin to the draining lymph node for presentation to antigen-specific T cells
    • Moll, H., H. Fuchs, C. Blank, and M. Röllinghoff. 1993. Langerhans cells transport Leishmania major from the infected skin to the draining lymph node for presentation to antigen-specific T cells. Eur. J. Immunol. 23:1595.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 1595
    • Moll, H.1    Fuchs, H.2    Blank, C.3    Röllinghoff, M.4
  • 52
    • 0036533626 scopus 로고    scopus 로고
    • Polarized Th cell response induction by transferred antigen-pulsed dendritic cells is dependent on IL-4 or IL-12 production by recipient cells
    • MacDonald, A. S., and E. J. Pearce. 2002. Polarized Th cell response induction by transferred antigen-pulsed dendritic cells is dependent on IL-4 or IL-12 production by recipient cells. J. Immunol. 168:3127.
    • (2002) J. Immunol. , vol.168 , pp. 3127
    • MacDonald, A.S.1    Pearce, E.J.2
  • 53
    • 0032528348 scopus 로고    scopus 로고
    • Human dendritic cell (DC)-based anti-infective therapy: Engineering DCs to secrete functional IFN-γ and IL-12
    • Ahuja, S. S., S. Mummidi, H. L. Malech, and S. K. Ahuja. 1998. Human dendritic cell (DC)-based anti-infective therapy: engineering DCs to secrete functional IFN-γ and IL-12. J. Immunol. 161:868.
    • (1998) J. Immunol. , vol.161 , pp. 868
    • Ahuja, S.S.1    Mummidi, S.2    Malech, H.L.3    Ahuja, S.K.4


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