-
1
-
-
0034654497
-
Controlling TGF-β signaling
-
Massague J, Chen YG. Controlling TGF-β signaling. Genes Dev. 2000; 14: 627-644.
-
(2000)
Genes Dev
, vol.14
, pp. 627-644
-
-
Massague, J.1
Chen, Y.G.2
-
2
-
-
0032529159
-
Smads and early developmental signaling by the TGFβ superfamily
-
Whitman M. Smads and early developmental signaling by the TGFβ superfamily. Genes Dev. 1998; 12: 2445-2462.
-
(1998)
Genes Dev
, vol.12
, pp. 2445-2462
-
-
Whitman, M.1
-
3
-
-
0032101178
-
Direct binding of Smad3 and Smad4 to critical TGF β-inducible element in the promoter of human plasminogen activator inhibitor-type1 gene
-
Dennler S, Itoh S, Vivien D, ten Dijke P, Huet S, Gauthier JM. Direct binding of Smad3 and Smad4 to critical TGF β-inducible element in the promoter of human plasminogen activator inhibitor-type1 gene. EMBO J 1998; 17: 3091-3100.
-
(1998)
EMBO J
, vol.17
, pp. 3091-3100
-
-
Dennler, S.1
Itoh, S.2
Vivien, D.3
ten Dijke, P.4
Huet, S.5
Gauthier, J.M.6
-
4
-
-
0034678908
-
Transcriptional control by the TGF-β/ Smad signaling system
-
Massuge J, Wotton D. Transcriptional control by the TGF-β/ Smad signaling system. EMBO J 2000; 19: 1745-1754.
-
(2000)
EMBO J
, vol.19
, pp. 1745-1754
-
-
Massuge, J.1
Wotton, D.2
-
5
-
-
28544446478
-
Requirement for SnoN oncoprotein in transforming growth factor β-induced oncogenic transformation of fibroblast cells
-
Zhu Q, Person-White S, Luo K. Requirement for SnoN oncoprotein in transforming growth factor β-induced oncogenic transformation of fibroblast cells. Mol Cell Biol 2005; 24: 10731-10744.
-
(2005)
Mol Cell Biol
, vol.24
, pp. 10731-10744
-
-
Zhu, Q.1
Person-White, S.2
Luo, K.3
-
6
-
-
0032934979
-
Targeted disruption of Smad3 reveals an essential role in transforming growth factor-β -mediated signal transduction
-
Datto MB, Frederick JP, Pan L, Borton AJ, Zhuang Y, Wang XF. Targeted disruption of Smad3 reveals an essential role in transforming growth factor-β -mediated signal transduction. Mol Cell Biol 1999; 19: 2495-2504.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 2495-2504
-
-
Datto, M.B.1
Frederick, J.P.2
Pan, L.3
Borton, A.J.4
Zhuang, Y.5
Wang, X.F.6
-
7
-
-
0033104503
-
Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-β
-
Yang X, Letterio JJ, Lechleider RJ, et al. Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-β. EMBO J 1999; 18: 1280-1291.
-
(1999)
EMBO J
, vol.18
, pp. 1280-1291
-
-
Yang, X.1
Letterio, J.J.2
Lechleider, R.J.3
-
8
-
-
0032482751
-
Failure of egg cylinder elongation and mesoderm induction in mouse embryos lacking the tumor suppressor Smad2
-
Weinstein M, Yang X, Li C, Xu X, Gotay J, Deng CX. Failure of egg cylinder elongation and mesoderm induction in mouse embryos lacking the tumor suppressor Smad2. Proc Natl Acad Sci USA 1998; 95: 9378-9383.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 9378-9383
-
-
Weinstein, M.1
Yang, X.2
Li, C.3
Xu, X.4
Gotay, J.5
Deng, C.X.6
-
9
-
-
0032565859
-
Smad2 role in mesoderm formation, left-right patterning and craniofacial development
-
Nomura M, Li E. Smad2 role in mesoderm formation, left-right patterning and craniofacial development. Nature 1998; 393: 786-790.
-
(1998)
Nature
, vol.393
, pp. 786-790
-
-
Nomura, M.1
Li, E.2
-
10
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 1998; 391: 806-811.
-
(1998)
Nature
, vol.391
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
Kostas, S.A.4
Driver, S.E.5
Mello, C.C.6
-
11
-
-
0033669621
-
Post-transcriptional gene silencing across kingdoms
-
Cogoni C, Macino G. Post-transcriptional gene silencing across kingdoms. Curr Opin Genet Dev 2000; 10: 638-694.
-
(2000)
Curr Opin Genet Dev
, vol.10
, pp. 638-694
-
-
Cogoni, C.1
Macino, G.2
-
13
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in mammalian cell culture
-
Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in mammalian cell culture. Nature 2001; 411: 494-498.
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
14
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
Brummelkamp TR, Bernards R, Agami R. A system for stable expression of short interfering RNAs in mammalian cells. Cell 2002; 296: 550-553.
-
(2002)
Cell
, vol.296
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
16
-
-
0037022382
-
Stable suppression of gene expression by RNAi in mammalian cell
-
Paddison PJ, Caudy AA, Hannon GJ. Stable suppression of gene expression by RNAi in mammalian cell. Proc Natl Acad Sci USA 2002; 99: 1443-1448.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 1443-1448
-
-
Paddison, P.J.1
Caudy, A.A.2
Hannon, G.J.3
-
17
-
-
1542336952
-
Rational siRNA design for RNA interference
-
Reynolds A, Leake D, Boese Q, Scaringe S, Marshall WS, Khvorova A. Rational siRNA design for RNA interference. Nat Biotechnol 2004; 22: 326-330.
-
(2004)
Nat Biotechnol
, vol.22
, pp. 326-330
-
-
Reynolds, A.1
Leake, D.2
Boese, Q.3
Scaringe, S.4
Marshall, W.S.5
Khvorova, A.6
-
18
-
-
0035905766
-
Role for a bidentate ribonuclease in the initiation step of RNA interference
-
Bernstein E, Caudy AA, Hammond SM, Hannon GJ. Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 2001; 409: 363-366.
-
(2001)
Nature
, vol.409
, pp. 363-366
-
-
Bernstein, E.1
Caudy, A.A.2
Hammond, S.M.3
Hannon, G.J.4
-
19
-
-
0037062951
-
RNA interference
-
Hannon GJ. RNA interference. Nature 2002; 418: 244-251.
-
(2002)
Nature
, vol.418
, pp. 244-251
-
-
Hannon, G.J.1
-
20
-
-
1642538990
-
Vector-based in vivo RNA interfence: Dose- and time- dependent suppression of transgene expression
-
Kobayashi N, Matsui Y, Kawase A, et al. Vector-based in vivo RNA interfence: dose- and time- dependent suppression of transgene expression. J Pharmacol Exp Ther 2004; 308: 688-693.
-
(2004)
J Pharmacol Exp Ther
, vol.308
, pp. 688-693
-
-
Kobayashi, N.1
Matsui, Y.2
Kawase, A.3
-
21
-
-
0037197914
-
RNA interfence by expression of short- interfering RNAs and hairpin RNAs in mammalian cells
-
Yu JY, DeRuiter SL, Turner DL. RNA interfence by expression of short- interfering RNAs and hairpin RNAs in mammalian cells. Proc Natl Acad Sci USA 2002; 99: 6047-6052.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 6047-6052
-
-
Yu, J.Y.1
DeRuiter, S.L.2
Turner, D.L.3
-
22
-
-
0036074161
-
RNA interference in human cells is restricted to the cytoplasm
-
Zeng Y, Cullen BR. RNA interference in human cells is restricted to the cytoplasm. RNA 2002; 8: 855-860.
-
(2002)
RNA
, vol.8
, pp. 855-860
-
-
Zeng, Y.1
Cullen, B.R.2
-
23
-
-
0037111232
-
Small interfering RNA-mediated gene sileneing in T-lymphocytes
-
McManus MT, Haines BB, Dillon CP, et al. Small interfering RNA-mediated gene sileneing in T-lymphocytes. J Immunol 2002; 169: 5754-5760.
-
(2002)
J Immunol
, vol.169
, pp. 5754-5760
-
-
McManus, M.T.1
Haines, B.B.2
Dillon, C.P.3
-
24
-
-
0037117550
-
A DNA vector-based RNAi technology to suppress gene expression in mammalian cells
-
Sui GC, Soohoo C, Affar el B, et al. A DNA vector-based RNAi technology to suppress gene expression in mammalian cells. Proc Natl Acad Sci USA 2002; 99: 5515-5520.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 5515-5520
-
-
Sui, G.C.1
Soohoo, C.2
Affar el, B.3
-
25
-
-
0036351317
-
Analysis of gene function in somatic mammlian cells using small interfering RNAs
-
Elbashir SM, Harborth J, Weber K, Tuschl T. Analysis of gene function in somatic mammlian cells using small interfering RNAs. Methods 2002; 26: 199-213.
-
(2002)
Methods
, vol.26
, pp. 199-213
-
-
Elbashir, S.M.1
Harborth, J.2
Weber, K.3
Tuschl, T.4
-
26
-
-
0142165224
-
Functional siRNAs and miRNA exhibit strand bias
-
Khvorova A, Reynolds A, Jayasena SD. Functional siRNAs and miRNA exhibit strand bias. Cell 2003; 115: 209-216.
-
(2003)
Cell
, vol.115
, pp. 209-216
-
-
Khvorova, A.1
Reynolds, A.2
Jayasena, S.D.3
-
27
-
-
0035863097
-
RNA interference is mediated by 21- and 22- nucleotide RNAs
-
Elbashir SM, Lendeckel W, Tuschl T. RNA interference is mediated by 21- and 22- nucleotide RNAs. Genes Dev 2001; 15: 188-200.
-
(2001)
Genes Dev
, vol.15
, pp. 188-200
-
-
Elbashir, S.M.1
Lendeckel, W.2
Tuschl, T.3
-
28
-
-
0034680863
-
Critical role of Smads and AP-1 complex in transforming growth factorbeta-dependent apoptosis
-
Yamamura Y, Hua X, Bergelson S, Lodish HF. Critical role of Smads and AP-1 complex in transforming growth factorbeta-dependent apoptosis. J Biol Chem 2000; 275: 36295-36302.
-
(2000)
J Biol Chem
, vol.275
, pp. 36295-36302
-
-
Yamamura, Y.1
Hua, X.2
Bergelson, S.3
Lodish, H.F.4
-
29
-
-
0033602186
-
A short amino-acid sequence in MH1domain is responsible for functional differences between Smad2 and Smad3
-
Dennler S, Huet S, Gauthier JM. A short amino-acid sequence in MH1domain is responsible for functional differences between Smad2 and Smad3. Oncogene 1999; 18: 1643-1648.
-
(1999)
Oncogene
, vol.18
, pp. 1643-1648
-
-
Dennler, S.1
Huet, S.2
Gauthier, J.M.3
-
30
-
-
0035827581
-
Functional characterization of transforming growth factor signaling in Smad2-and Smad3-deficient fibroblasts
-
Piek E, Ju WJ, Heyer J, et al. Functional characterization of transforming growth factor signaling in Smad2-and Smad3-deficient fibroblasts. J Biol Cell 2001; 276: 19945-19953.
-
(2001)
J Biol Cell
, vol.276
, pp. 19945-19953
-
-
Piek, E.1
Ju, W.J.2
Heyer, J.3
-
31
-
-
33645704946
-
EM703 improves bleomycin-induces pulmonary fibrosis in mice by the inhibition of TGF-β signaling in lung fibroblasts
-
Li YJ, Azuma A, Usuki J, et al. EM703 improves bleomycin-induces pulmonary fibrosis in mice by the inhibition of TGF-β signaling in lung fibroblasts. Respir Res 2006; 7: 16.
-
(2006)
Respir Res
, vol.7
, pp. 16
-
-
Li, Y.J.1
Azuma, A.2
Usuki, J.3
-
32
-
-
0036293202
-
Regulation of Smad3 expression in bleomycin-induced pulmonary fibrosis: A negative feedback loop of TGF-β singnaling
-
Zhao Y, Geverd DA. Regulation of Smad3 expression in bleomycin-induced pulmonary fibrosis: a negative feedback loop of TGF-β singnaling. Biochem Biophys Res Commun 2002; 294: 319-323.
-
(2002)
Biochem Biophys Res Commun
, vol.294
, pp. 319-323
-
-
Zhao, Y.1
Geverd, D.A.2
-
33
-
-
26244439497
-
The endogenous ratio of Smad2 and Smad3 influences the cytostatic function of Smad3
-
Kim SG, Kim HA, Jong HS, et al. The endogenous ratio of Smad2 and Smad3 influences the cytostatic function of Smad3. Mol Biol Cell 2005; 16: 4672-4683.
-
(2005)
Mol Biol Cell
, vol.16
, pp. 4672-4683
-
-
Kim, S.G.1
Kim, H.A.2
Jong, H.S.3
-
34
-
-
0036670339
-
Nucleocytoplasmic shuttling of Smads 2, 3, and 4 permits sensing of TGF-β receptor activity
-
Inman GJ, Nicolás FJ, Hill CS. Nucleocytoplasmic shuttling of Smads 2, 3, and 4 permits sensing of TGF-β receptor activity. Mol Cell 2002; 10: 283-294.
-
(2002)
Mol Cell
, vol.10
, pp. 283-294
-
-
Inman, G.J.1
Nicolás, F.J.2
Hill, C.S.3
-
35
-
-
0034618406
-
Functional consequences of tumorigenic missense mutations in the aminoterminal domain of Smad4
-
Moren A, Itoh S, Moustakas A, ten Dijke P, Heldin C-H. Functional consequences of tumorigenic missense mutations in the aminoterminal domain of Smad4. Oncogene 2000; 19: 4396-4404.
-
(2000)
Oncogene
, vol.19
, pp. 4396-4404
-
-
Moren, A.1
Itoh, S.2
Moustakas, A.3
ten Dijke, P.4
Heldin, C.-H.5
-
36
-
-
0035123060
-
The L3 loop and C-terminal phosphorylation jointly define Smad protein trimerization
-
Chacko BM, Qin B, Correia JJ, Lam SS, de Caestecker MP, Lin K. The L3 loop and C-terminal phosphorylation jointly define Smad protein trimerization. Nat Struct Biol 2001; 8: 248-253.
-
(2001)
Nat Struct Biol
, vol.8
, pp. 248-253
-
-
Chacko, B.M.1
Qin, B.2
Correia, J.J.3
Lam, S.S.4
de Caestecker, M.P.5
Lin, K.6
-
37
-
-
0035827668
-
Formation of a stable heterodimer between Smad2 and Smad4
-
Wu JW, Fairman R, Penry J, Shi Y. Formation of a stable heterodimer between Smad2 and Smad4. J Biol Chem 2001; 276: 20688-20694.
-
(2001)
J Biol Chem
, vol.276
, pp. 20688-20694
-
-
Wu, J.W.1
Fairman, R.2
Penry, J.3
Shi, Y.4
-
38
-
-
0030690337
-
Dual role of the Smad4/DPC4 tumor suppressor in TGF inducible transcriptional complexes
-
Liu F, Pouponnot C, Massague J. Dual role of the Smad4/DPC4 tumor suppressor in TGF inducible transcriptional complexes. Genes Dev 1997; 11: 3157-3167.
-
(1997)
Genes Dev
, vol.11
, pp. 3157-3167
-
-
Liu, F.1
Pouponnot, C.2
Massague, J.3
-
39
-
-
0034695483
-
Targeted disruption in murine cells reveals variable requirement for Smad4 in transforming growth factor betarelated signaling
-
Sirard C, Kim S, Mirtsos C, et al. Targeted disruption in murine cells reveals variable requirement for Smad4 in transforming growth factor betarelated signaling. J Biol Chem 2000; 21: 2063-2070.
-
(2000)
J Biol Chem
, vol.21
, pp. 2063-2070
-
-
Sirard, C.1
Kim, S.2
Mirtsos, C.3
|