-
1
-
-
41349116135
-
The eukaryotic genome as an RNA machine
-
Amaral, P. P., Dinger, M. E., Mercer, T. R. and Mattick, J. S. (2008) The eukaryotic genome as an RNA machine. Science 319, 1787-1789
-
(2008)
Science
, vol.319
, pp. 1787-1789
-
-
Amaral, P.P.1
Dinger, M.E.2
Mercer, T.R.3
Mattick, J.S.4
-
2
-
-
24644446398
-
Ribo-gnome: The big world of small RNAs
-
Zamore, P. D. and Haley, B. (2005) Ribo-gnome: the big world of small RNAs. Science 309, 1519-1524
-
(2005)
Science
, vol.309
, pp. 1519-1524
-
-
Zamore, P.D.1
Haley, B.2
-
3
-
-
4644309196
-
The functions of animal microRNAs
-
Ambros, V. (2004) The functions of animal microRNAs. Nature 431, 350-355
-
(2004)
Nature
, vol.431
, pp. 350-355
-
-
Ambros, V.1
-
4
-
-
39949083375
-
Conserved themes in small-RNA-mediated transposon control
-
Girard, A. and Hannon, G. J. (2008) Conserved themes in small-RNA-mediated transposon control. Trends Cell Biol. 18, 136-148
-
(2008)
Trends Cell Biol
, vol.18
, pp. 136-148
-
-
Girard, A.1
Hannon, G.J.2
-
6
-
-
41149147013
-
Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure
-
Chen, J. F., Murchison, E. P., Tang, R., Callis, T. E., Tatsuguchi, M., Deng, Z., Rojas, M., Hammond, S. M., Schneider, M. D., Selzman, C. H. et al. (2008) Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure. Proc. Natl. Acad. Sci. U.S.A. 105, 2111-2116
-
(2008)
Proc. Natl. Acad. Sci. U.S.A
, vol.105
, pp. 2111-2116
-
-
Chen, J.F.1
Murchison, E.P.2
Tang, R.3
Callis, T.E.4
Tatsuguchi, M.5
Deng, Z.6
Rojas, M.7
Hammond, S.M.8
Schneider, M.D.9
Selzman, C.H.10
-
7
-
-
0036828639
-
The Argonaute family: Tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis
-
Carmell, M. A., Xuan, Z., Zhang, M. Q. and Hannon, G. J. (2002) The Argonaute family: tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis. Genes Dev. 16, 2733-2742
-
(2002)
Genes Dev
, vol.16
, pp. 2733-2742
-
-
Carmell, M.A.1
Xuan, Z.2
Zhang, M.Q.3
Hannon, G.J.4
-
8
-
-
33750366095
-
Argonaute: A scaffold for the function of short regulatory BNAs
-
Parker, J. S. and Barford, D. (2006) Argonaute: a scaffold for the function of short regulatory BNAs. Trends Biochem. Sci. 31, 622-630
-
(2006)
Trends Biochem. Sci
, vol.31
, pp. 622-630
-
-
Parker, J.S.1
Barford, D.2
-
9
-
-
33845774243
-
-
Tolia, N. H. and Joshua-Tor, L. (2007) Slicer and the Argonautes. Nat. Chem. Biol. 3, 36-43
-
Tolia, N. H. and Joshua-Tor, L. (2007) Slicer and the Argonautes. Nat. Chem. Biol. 3, 36-43
-
-
-
-
10
-
-
34249810892
-
Argonaute proteins: Mediators of RNA silencing
-
Peters, L. and Meister, G. (2007) Argonaute proteins: mediators of RNA silencing. Mol. Cell 26, 611-623
-
(2007)
Mol. Cell
, vol.26
, pp. 611-623
-
-
Peters, L.1
Meister, G.2
-
11
-
-
37549014207
-
Argonaute proteins: Key players in RNA silencing
-
Hutvagner, G. and Simard, M. J. (2008) Argonaute proteins: key players in RNA silencing. Nat. Rev. Mol. Cell Biol. 9, 22-32
-
(2008)
Nat. Rev. Mol. Cell Biol
, vol.9
, pp. 22-32
-
-
Hutvagner, G.1
Simard, M.J.2
-
12
-
-
0036792769
-
Fragile X-related protein and VIG associate with the RNA interference machinery
-
Caudy, A. A., Myers, M., Hannon, G. J. and Hammond, S. M. (2002) Fragile X-related protein and VIG associate with the RNA interference machinery. Genes Dev. 16, 2491-2496
-
(2002)
Genes Dev
, vol.16
, pp. 2491-2496
-
-
Caudy, A.A.1
Myers, M.2
Hannon, G.J.3
Hammond, S.M.4
-
13
-
-
0037144546
-
A microRNA in a multiple-turnover RNAi enzyme complex
-
Hutvagner, G. and Zamore, P. D. (2002) A microRNA in a multiple-turnover RNAi enzyme complex. Science 297, 2056-2060
-
(2002)
Science
, vol.297
, pp. 2056-2060
-
-
Hutvagner, G.1
Zamore, P.D.2
-
14
-
-
0036791671
-
A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins
-
Ishizuka, A., Siomi, M. C. and Siomi, H. (2002) A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins. Genes Dev. 16, 2497-2508
-
(2002)
Genes Dev
, vol.16
, pp. 2497-2508
-
-
Ishizuka, A.1
Siomi, M.C.2
Siomi, H.3
-
15
-
-
0037087780
-
miRNPs: A novel class of ribonucleoproteins containing numerous microRNAs
-
Mourelatos, Z., Dostie, J., Paushkin, S., Sharma, A., Charroux, B., Abel, L., Rappsilber, J., Mann, M. and Dreyfuss, G. (2002) miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs. Genes Dev. 16, 720-728
-
(2002)
Genes Dev
, vol.16
, pp. 720-728
-
-
Mourelatos, Z.1
Dostie, J.2
Paushkin, S.3
Sharma, A.4
Charroux, B.5
Abel, L.6
Rappsilber, J.7
Mann, M.8
Dreyfuss, G.9
-
16
-
-
4444368187
-
Argonaute2 is the catalytic engine of mammalian RNAi
-
Liu, J., Carmell, M. A., Rivas, F. V., Marsden, C. G., Thomson, J. M., Song, J. J., Hammond, S. M., Joshua-Tor, L. and Hannon, G. J. (2004) Argonaute2 is the catalytic engine of mammalian RNAi. Science 305, 1437-1441
-
(2004)
Science
, vol.305
, pp. 1437-1441
-
-
Liu, J.1
Carmell, M.A.2
Rivas, F.V.3
Marsden, C.G.4
Thomson, J.M.5
Song, J.J.6
Hammond, S.M.7
Joshua-Tor, L.8
Hannon, G.J.9
-
17
-
-
3242736704
-
Human argonaute2 mediates RNA cleavage targeted by miRNAs and SiRNAs
-
Meister, G., Landthaler, M., Patkaniowska, A., Dorsett, Y., Teng, G. and Tuschl, T. (2004) Human argonaute2 mediates RNA cleavage targeted by miRNAs and SiRNAs. Mol. Cell 15, 185-197
-
(2004)
Mol. Cell
, vol.15
, pp. 185-197
-
-
Meister, G.1
Landthaler, M.2
Patkaniowska, A.3
Dorsett, Y.4
Teng, G.5
Tuschl, T.6
-
18
-
-
33745402414
-
A novel class of small RNAs bind to MILI protein in mouse testes
-
Aravin, A., Gaidatzis, D., Pfeffer, S., Lagos-Quintana, M., Landgraf, P., Iovino, N., Morris, P., Brownstein, M. J., Kuramochi-Miyagawa, S., Nakano, T. et al. (2006) A novel class of small RNAs bind to MILI protein in mouse testes. Nature 442, 203-207
-
(2006)
Nature
, vol.442
, pp. 203-207
-
-
Aravin, A.1
Gaidatzis, D.2
Pfeffer, S.3
Lagos-Quintana, M.4
Landgraf, P.5
Iovino, N.6
Morris, P.7
Brownstein, M.J.8
Kuramochi-Miyagawa, S.9
Nakano, T.10
-
19
-
-
33745336617
-
A germline-specific class of small RNAs binds mammalian Piwi proteins
-
Girard, A., Sachidanandam, R., Hannon, G. J. and Carmell, M. A. (2006) A germline-specific class of small RNAs binds mammalian Piwi proteins. Nature 442, 199-202
-
(2006)
Nature
, vol.442
, pp. 199-202
-
-
Girard, A.1
Sachidanandam, R.2
Hannon, G.J.3
Carmell, M.A.4
-
20
-
-
33745621037
-
A novel class of small RNAs in mouse spermatogenic cells
-
Grivna, S. T., Beyret, E., Wang, Z. and Lin, H. (2006) A novel class of small RNAs in mouse spermatogenic cells. Genes Dev. 20, 1709-1714
-
(2006)
Genes Dev
, vol.20
, pp. 1709-1714
-
-
Grivna, S.T.1
Beyret, E.2
Wang, Z.3
Lin, H.4
-
21
-
-
33748339362
-
Involvement of AGO1 and AGO2 in mammalian transcriptional silencing
-
Janowski, B. A., Huffman, K. E., Schwartz, J. C., Ram, R., Nordsell, R., Shames, D. S., Minna, J. D. and Corey, D. R. (2006) Involvement of AGO1 and AGO2 in mammalian transcriptional silencing. Nat. Struct. Mol. Biol. 13, 787-792
-
(2006)
Nat. Struct. Mol. Biol
, vol.13
, pp. 787-792
-
-
Janowski, B.A.1
Huffman, K.E.2
Schwartz, J.C.3
Ram, R.4
Nordsell, R.5
Shames, D.S.6
Minna, J.D.7
Corey, D.R.8
-
22
-
-
3142615372
-
The RNAi revolution
-
Novina, C. D. and Sharp, P. A. (2004) The RNAi revolution. Nature 430, 161-164
-
(2004)
Nature
, vol.430
, pp. 161-164
-
-
Novina, C.D.1
Sharp, P.A.2
-
23
-
-
33644768174
-
Control of translation and mRNA degradation by miRNAs and siRNAs
-
Valencia-Sanchez, M. A., Liu, J., Hannon, G. J. and Parker, R. (2006) Control of translation and mRNA degradation by miRNAs and siRNAs. Genes Dev. 20, 515-524
-
(2006)
Genes Dev
, vol.20
, pp. 515-524
-
-
Valencia-Sanchez, M.A.1
Liu, J.2
Hannon, G.J.3
Parker, R.4
-
24
-
-
4644310115
-
Tethering of human Ago proteins to mRNA mimics the miRNA-mediated repression of protein synthesis
-
Pillai, R. S., Artus, C. G. and Filipowicz, W. (2004) Tethering of human Ago proteins to mRNA mimics the miRNA-mediated repression of protein synthesis. RNA 10, 1518-1525
-
(2004)
RNA
, vol.10
, pp. 1518-1525
-
-
Pillai, R.S.1
Artus, C.G.2
Filipowicz, W.3
-
25
-
-
4444302947
-
Crystal structure of argonaute and its implications for RISC slicer activity
-
Song, J. J., Smith, S. K., Hannon, G. J. and Joshua-Tor, L. (2004) Crystal structure of argonaute and its implications for RISC slicer activity. Science 305, 1434-1437
-
(2004)
Science
, vol.305
, pp. 1434-1437
-
-
Song, J.J.1
Smith, S.K.2
Hannon, G.J.3
Joshua-Tor, L.4
-
26
-
-
18744407284
-
Purified argonaute2 and an siRNA form recombinant human RISC
-
Rivas, F. V., Tolia, N. H., Song, J. J., Aragon, J. P., Liu, J., Hannon, G. J. and Joshua-Tor, L. (2005) Purified argonaute2 and an siRNA form recombinant human RISC. Nat. Struct. Mol. Biol. 12, 340-349
-
(2005)
Nat. Struct. Mol. Biol
, vol.12
, pp. 340-349
-
-
Rivas, F.V.1
Tolia, N.H.2
Song, J.J.3
Aragon, J.P.4
Liu, J.5
Hannon, G.J.6
Joshua-Tor, L.7
-
27
-
-
23144438396
-
Crystal structure of A. aeolicus argonaute, a site-specific DNA-guided endoribonuclease, provides insights into RISC-mediated mRNA cleavage
-
Yuan, Y. R., Pei, Y., Ma, J. B., Kuryavyi, V., Zhadina, M., Meister, G., Chen, H. Y. Dauter, Z., Tuschl, T. and Patel, D. J. (2005) Crystal structure of A. aeolicus argonaute, a site-specific DNA-guided endoribonuclease, provides insights into RISC-mediated mRNA cleavage. Mol. Cell 19, 405-419
-
(2005)
Mol. Cell
, vol.19
, pp. 405-419
-
-
Yuan, Y.R.1
Pei, Y.2
Ma, J.B.3
Kuryavyi, V.4
Zhadina, M.5
Meister, G.6
Chen, H.Y.7
Dauter, Z.8
Tuschl, T.9
Patel, D.J.10
-
28
-
-
34547955952
-
A slicer-independent role for argonaute 2 in hematopoiesis and the microRNA pathway
-
O'Carroll, D., Mecklenbrauker, I., Das, P. P., Santana, A., Koenig, U., Enright, A. J., Miska, E. A. and Tarakhovsky, A. (2007) A slicer-independent role for argonaute 2 in hematopoiesis and the microRNA pathway. Genes Dev. 21, 1999-2004
-
(2007)
Genes Dev
, vol.21
, pp. 1999-2004
-
-
O'Carroll, D.1
Mecklenbrauker, I.2
Das, P.P.3
Santana, A.4
Koenig, U.5
Enright, A.J.6
Miska, E.A.7
Tarakhovsky, A.8
-
29
-
-
36849048778
-
Dual role for argonautes in microRNA processing and posttranscriptional regulation of microRNA expression
-
Diederichs, S. and Haber, D. A. (2007) Dual role for argonautes in microRNA processing and posttranscriptional regulation of microRNA expression. Cell 131, 1097-1108
-
(2007)
Cell
, vol.131
, pp. 1097-1108
-
-
Diederichs, S.1
Haber, D.A.2
-
30
-
-
33744973775
-
Relief of microRNA-mediated translational repression in human cells subjected to stress
-
Bhattacharyya, S. N., Habermacher, R., Martine, U., Closs, E. I. and Filipowicz, W. (2006) Relief of microRNA-mediated translational repression in human cells subjected to stress. Cell 125, 1111-1124
-
(2006)
Cell
, vol.125
, pp. 1111-1124
-
-
Bhattacharyya, S.N.1
Habermacher, R.2
Martine, U.3
Closs, E.I.4
Filipowicz, W.5
-
31
-
-
36749026906
-
Switching from repression to activation: MicroRNAs can up-regulate translation
-
Vasudevan, S., Tong, Y. and Steitz, J. A. (2007) Switching from repression to activation: microRNAs can up-regulate translation. Science 318, 1931-1934
-
(2007)
Science
, vol.318
, pp. 1931-1934
-
-
Vasudevan, S.1
Tong, Y.2
Steitz, J.A.3
-
32
-
-
33845295461
-
Quantitative analysis of Argonaute protein reveals microRNA-dependent localization to stress granules
-
Leung, A. K., Calabrese, J. M. and Sharp, P. A. (2006) Quantitative analysis of Argonaute protein reveals microRNA-dependent localization to stress granules. Proc. Natl. Acad. Sci. U.S.A. 103, 18125-18130
-
(2006)
Proc. Natl. Acad. Sci. U.S.A
, vol.103
, pp. 18125-18130
-
-
Leung, A.K.1
Calabrese, J.M.2
Sharp, P.A.3
-
33
-
-
24644480213
-
Inhibition of translational initiation by Let-7 microRNA in human cells
-
Pillai, R. S., Bhattacharyya, S. N., Artus, C. G., Zoller, T., Cougot, N., Basyuk, E., Bertrand, E. and Filipowicz, W. (2005) Inhibition of translational initiation by Let-7 microRNA in human cells. Science 309, 1573-1576
-
(2005)
Science
, vol.309
, pp. 1573-1576
-
-
Pillai, R.S.1
Bhattacharyya, S.N.2
Artus, C.G.3
Zoller, T.4
Cougot, N.5
Basyuk, E.6
Bertrand, E.7
Filipowicz, W.8
-
34
-
-
20444427566
-
Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies
-
Sen, G. L. and Blau, H. M. (2005) Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies. Nat. Cell Biol. 7, 633-636
-
(2005)
Nat. Cell Biol
, vol.7
, pp. 633-636
-
-
Sen, G.L.1
Blau, H.M.2
-
35
-
-
22144478256
-
MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies
-
Liu, J., Valencia-Sanchez, M. A., Hannon, G. J. and Parker, R. (2005) MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies. Nat. Cell Biol. 7, 719-723
-
(2005)
Nat. Cell Biol
, vol.7
, pp. 719-723
-
-
Liu, J.1
Valencia-Sanchez, M.A.2
Hannon, G.J.3
Parker, R.4
-
36
-
-
15744392181
-
Regulation of zipper-interacting protein kinase activity in vitro and in vivo by multisite phosphorylation
-
Graves, P. R., Winkfield, K. M. and Haystead, T. A. (2005) Regulation of zipper-interacting protein kinase activity in vitro and in vivo by multisite phosphorylation. J. Biol. Chem. 280, 9363-9374
-
(2005)
J. Biol. Chem
, vol.280
, pp. 9363-9374
-
-
Graves, P.R.1
Winkfield, K.M.2
Haystead, T.A.3
-
37
-
-
0025998840
-
Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates
-
Boyle, W. J., van der Geer, P. and Hunter, T. (1991) Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates. Methods Enzymol. 201, 110-149
-
(1991)
Methods Enzymol
, vol.201
, pp. 110-149
-
-
Boyle, W.J.1
van der Geer, P.2
Hunter, T.3
-
38
-
-
0027212498
-
Solubilization and purification of enzymatically active glutathione S-transferase (pGEX) fusion proteins
-
Frangioni, J. V. and Neel, B. G. (1993) Solubilization and purification of enzymatically active glutathione S-transferase (pGEX) fusion proteins. Anal. Biochem. 210, 179-187
-
(1993)
Anal. Biochem
, vol.210
, pp. 179-187
-
-
Frangioni, J.V.1
Neel, B.G.2
-
39
-
-
0027739284
-
The substrate specificity and structure of mitogen-activated protein (MAP) kinase-activated protein kinase-2
-
Stokoe, D., Caudwell, B., Cohen, P. T. and Cohen, P. (1993) The substrate specificity and structure of mitogen-activated protein (MAP) kinase-activated protein kinase-2. Biochem. J. 296, 843-849
-
(1993)
Biochem. J
, vol.296
, pp. 843-849
-
-
Stokoe, D.1
Caudwell, B.2
Cohen, P.T.3
Cohen, P.4
-
40
-
-
33244471768
-
MAPKAP kinases - MKs - two's company, three's a crowd
-
Gaestel, M. (2006) MAPKAP kinases - MKs - two's company, three's a crowd. Nat. Rev. Mol. Cell Biol. 7, 120-130
-
(2006)
Nat. Rev. Mol. Cell Biol
, vol.7
, pp. 120-130
-
-
Gaestel, M.1
-
41
-
-
34247364093
-
Mechanisms of microRNA-mediated gene regulation in animal cells
-
Nilsen, T. W. (2007) Mechanisms of microRNA-mediated gene regulation in animal cells. Trends Genet. 23, 243-249
-
(2007)
Trends Genet
, vol.23
, pp. 243-249
-
-
Nilsen, T.W.1
-
42
-
-
33846277696
-
Repression of protein synthesis by miRNAs: How many mechanisms?
-
Pillai, R. S., Bhattacharyya, S. N. and Filipowicz, W. (2007) Repression of protein synthesis by miRNAs: how many mechanisms? Trends Cell Biol. 17, 118-126
-
(2007)
Trends Cell Biol
, vol.17
, pp. 118-126
-
-
Pillai, R.S.1
Bhattacharyya, S.N.2
Filipowicz, W.3
-
43
-
-
34347335707
-
P-body formation is a consequence, not the cause, of RNA-mediated gene silencing
-
Eulalio, A., Behm-Ansmant, I., Schweizer, D. and Izaurralde, E. (2007) P-body formation is a consequence, not the cause, of RNA-mediated gene silencing. Mol. Cell. Biol. 27, 3970-3981
-
(2007)
Mol. Cell. Biol
, vol.27
, pp. 3970-3981
-
-
Eulalio, A.1
Behm-Ansmant, I.2
Schweizer, D.3
Izaurralde, E.4
-
44
-
-
33745894330
-
Translation repression in human cells by microRNA-induced gene silencing requires RCK/p54
-
Chu, C. Y. and Rana, T. M. (2006) Translation repression in human cells by microRNA-induced gene silencing requires RCK/p54. PLoS Biol. 4, e210
-
(2006)
PLoS Biol
, vol.4
-
-
Chu, C.Y.1
Rana, T.M.2
-
45
-
-
34548478113
-
Small interfering RNA-mediated silencing induces target-dependent assembly of GW/P bodies
-
Lian, S., Fritzler, M. J., Katz, J., Hamazaki, T., Terada, N., Satoh, M. and Chan, E. K. (2007) Small interfering RNA-mediated silencing induces target-dependent assembly of GW/P bodies. Mol. Biol. Cell 18, 3375-3387
-
(2007)
Mol. Biol. Cell
, vol.18
, pp. 3375-3387
-
-
Lian, S.1
Fritzler, M.J.2
Katz, J.3
Hamazaki, T.4
Terada, N.5
Satoh, M.6
Chan, E.K.7
|