Functional recovery after human umbilical cord blood cells transplantation with brain-derived neutrophic factor into the spinal cord injured rat

Acta Neurochirurgica

Volumn 147, Issue 9, 2005, Pages 985-992

  Kuh, S U ^a   Cho, Y E ^a   Yoon, D H ^a   Kim, K N ^a   Ha, Y ^b  

^a Yonsei University   (South Korea)

^b Inha University School of Medicine   (South Korea)

Author keywords

BDNF; Cell transplantation; Human umbilical cord blood cells (HUCBs); Spinal cord injury

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN STEM; CELL DIFFERENTIATION; CELL TRANSFER; CELL TRANSPLANTATION; CONTROLLED STUDY; CONVALESCENCE; IMMUNOFLUORESCENCE TEST; IMMUNOGOLD LABELING; MALE; MOTOR PERFORMANCE; NERVE CELL; NERVE FIBER REGENERATION; NONHUMAN; PRIORITY JOURNAL; RAT; RETROGRADE NERVE FIBER TRANSPORT; SCORING SYSTEM; SPINAL CORD INJURY; UMBILICAL CORD BLOOD;

ANIMALS; BIOLOGICAL MARKERS; BRAIN STEM; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; CORD BLOOD STEM CELL TRANSPLANTATION; EFFERENT PATHWAYS; GLIAL FIBRILLARY ACIDIC PROTEIN; GRAFT SURVIVAL; GROWTH CONES; HUMANS; MALE; MICROTUBULE-ASSOCIATED PROTEINS; NERVE REGENERATION; NEUROGLIA; NEURONS; PLURIPOTENT STEM CELLS; RATS; RATS, SPRAGUE-DAWLEY; RECOVERY OF FUNCTION; SPINAL CORD INJURIES; TRANSPLANTATION, HETEROLOGOUS; TREATMENT OUTCOME;

EID: 23844436492     PISSN: 00016268     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00701-005-0538-y     Document Type: Article

References (37)

1. DM Basso MS Beattie JC Bresnahan DK Anderson AI Faden JA Gruner 1996 MASCIS evaluation of open field locomotor scores: effects of experience and teamwork on reliability. Multicenter Animal Spinal Cord Injury Study. J Neurotrauma 13 343 359
2. H Bernstein-Goral BS Bregman 1993 Spinal cord transplants support the regeneration of axotomized neurons after spinal cord lesions at birth: a quantitative double-labeling study. Exp Neurol 123 118 132
3. AR Bicknese HS Goodwin CO Quinn VC Henderson SN Chien DA Wall 2002 Human umbilical cord blood cells can be induced to express markers for neurons and glia. Cell Transplant 11 261 264
4. A Blesch P Lu MH Tuszynski 2002 Neurotrophic factors, gene therapy, and neural stem cells for spinal cord repair. Brain Res Bull 57 833 838
5. BS Bregman M McAtee HN Dai PL Kuhn 1997 Neurotrophic factors increase axonal growth after spinal cord injury and transplantation in the adult rat. Exp Neurol 148 475 494
6. L Buzanska EK Machaj B Zablocka Z Pojda K Domanska-Janik 2002 Human cord blood-derived cells attain neuronal and glial features in vitro. J Cell Sci 115 2131 2138
7. J Chen Y Li M Chopp 2000 Intracerebral transplantation of bone marrow with BDNF after MCAo in rat. Neuropharmacology 39 711 716
8. JV Coumans TT Lin HN Dai L MacArthur M McAtee C Nash 2001 Axonal regeneration and functional recovery after complete spinal cord transection in rats by delayed treatment with transplants and neurotrophins. J Neurosci 21 9334 9344
9. M Dezawa 2002 Central and peripheral nerve regeneration by transplantation of Schwann cells and transdifferentiated bone marrow stromal cells. Anat Sci Int 77 12 25
10. PS Diener BS Bregman 1994 Neurotrophic factors prevent the death of CNS neurons after spinal cord lesions in newborn rats. Neuroreport 5 1913 1917
11. RJ Franklin 2002 Remyelination of the demyelinated CNS: the case for and against transplantation of central, peripheral and olfactory glia. Brain Res Bull 57 827 832
12. EL Goh D Ma GL Ming H Song 2003 Adult neural stem cells and repair of the adult central nervous system. J Hematother Stem Cell Res 12 671 679
13. HS Goodwin AR Bicknese SN Chien BD Bogucki CO Quinn DA Wall 2001 Multilineage differentiation activity by cells isolated from umbilical cord blood: expression of bone, fat, and neural markers. Biol Blood Marrow Transplant 7 581 588
14. JD Guest D Hesse L Schnell ME Schwab MB Bunge RP Bunge 1997 Influence of IN-1 antibody and acidic FGF-fibrin glue on the response of injured corticospinal tract axons to human Schwann cell grafts. J Neurosci Res 50 888 905
15. Y Ha JU Choi DH Yoon DS Yeon JJ Lee HO Kim 2001 Neural phenotype expression of cultured human cord blood cells in vitro. Neuroreport 12 3523 3527
16. FP Hamers AJ Lankhorst TJ van Laar WB Veldhuis WH Gispen 2001 Automated quantitative gait analysis during overground locomotion in the rat: its application to spinal cord contusion and transection injuries. J Neurotrauma 18 187 201
17. JD Houle JH Ye 1997 Changes occur in the ability to promote axonal regeneration as the post-injury period increases. Neuroreport 8 751 755
18. JD Houle JH Ye 1999 Survival of chronically-injured neurons can be prolonged by treatment with neurotrophic factors. Neuroscience 94 929 936
19. DA Houweling JT van Asseldonk AJ Lankhorst FP Hamers D Martin PR Bar 1998 Local application of collagen containing brain-derived neurotrophic factor decreases the loss of function after spinal cord injury in the adult rat. Neurosci Lett 251 193 196
20. K Ishii M Toda Y Nakai H Asou M Watanabe M Nakamura 2001 Increase of oligodendrocyte progenitor cells after spinal cord injury. J Neurosci Res 65 500 507
21. BK Kwon W Tetzlaff 2001 Spinal cord regeneration: from gene to transplants. Spine 26 S13 S22
22. P Lu LL Jones EY Snyder MH Tuszynski 2003 Neural stem cells constitutively secrete neurotrophic factors and promote extensive host axonal growth after spinal cord injury. Exp Neurol 181 115 129
23. JW McDonald MJ Howard 2002 Repairing the damaged spinal cord: a summary of our early success with embryonic stem cell transplantation and remyelination. Prog Brain Res 137 299 309
24. GA Metz D Merkler V Dietz ME Schwab K Fouad 2000 Efficient testing of motor function in spinal cord injured rats. Brain Res 883 165 177
25. T Murakami Y Fujimoto Y Yasunaga O Ishida N Tanaka Y Ikuta 2003 Transplanted neuronal progenitor cells in a peripheral nerve gap promote nerve repair. Brain Res 974 17 24
26. M Nakamura Y Toyama 2003 Transplantation of neural stem cells into spinal cord after injury. Nippon Rinsho 61 463 468
27. A Privat 2003 Repair of the mammalian central nervous system: the "spinal cord" model. Bull Acad Natl Med 187 345 357
28. JR Sanchez-Ramos 2002 Neural cells derived from adult bone marrow and umbilical cord blood. J Neurosci Res 69 880 893
29. SW Scheff DA Saucier ME Cain 2002 A statistical method for analyzing rating scale data: the BBB locomotor score. J Neurotrauma 19 1251 1260
30. U Slawinska 2002 Transplants as a therapy after spinal cord injury. Neurol Neurochir Pol 36 [Suppl 1] 73 94
31. S Song J Sanchez-Ramos 2002 Preparation of neural progenitors from bone marrow and umbilical cord blood. Methods Mol Biol 198 79 88
32. Y Sun J Shi SL Fu PH Lu XM Xu 2003 Effects of embryonic neural stem cells and glial cell line-derived neurotrophic factor in the repair of spinal cord injury. Sheng Li Xue Bao 55 349 354
33. M Vroemen L Aigner J Winkler N Weidner 2003 Adult neural progenitor cell grafts survive after acute spinal cord injury and integrate along axonal pathways. Eur J Neurosci 18 743 751
34. NR West V Leblanc GH Collins 2001 Support of axonal regrowth by endogenous mechanisms following spinal cord injury in adult rats. Neuropathology 21 188 202
35. S Woerly VD Doan F Evans-Martin CG Paramore JD Peduzzi 2001 Spinal cord reconstruction using NeuroGel implants and functional recovery after chronic injury. J Neurosci Res 66 1187 1197
36. XM Xu V Guenard N Kleitman P Aebischer MB Bunge 1995 A combination of BDNF and NT-3 promotes supraspinal axonal regeneration into Schwann cell grafts in adult rat thoracic spinal cord. Exp Neurol 134 261 272
37. T Zigova S Song AE Willing JE Hudson MB Newman S Saporta 2002 Human umbilical cord blood cells express neural antigens after transplantation into the developing rat brain. Cell Transplant 11 265 274