메뉴 건너뛰기




Volumn 21, Issue 6, 2008, Pages 345-355

Over-expression of the thrombin receptor (PAR-1) in the placenta in preeclampsia: A mechanism for the intersection of coagulation and inflammation

Author keywords

Immunohistochemistry; PAR 1; Preterm; Tethered ligand; Trophoblast; Villous infarct

Indexed keywords

PROTEINASE ACTIVATED RECEPTOR 1; THROMBIN RECEPTOR;

EID: 47349114249     PISSN: 14767058     EISSN: 14764954     Source Type: Journal    
DOI: 10.1080/14767050802034859     Document Type: Article
Times cited : (42)

References (143)
  • 1
    • 0015393205 scopus 로고
    • On the pathogenesis of placental infarcts in pre-eclampsia
    • Brosens I, Renaer M. On the pathogenesis of placental infarcts in pre-eclampsia. J Obstet Gynaecol Br Commonw 1972;79:794-799.
    • (1972) J Obstet Gynaecol Br Commonw , vol.79 , pp. 794-799
    • Brosens, I.1    Renaer, M.2
  • 2
    • 0036547768 scopus 로고    scopus 로고
    • Placental pathology in early onset pre-eclampsia and intra-uterine growth restriction in women with and without thrombophilia
    • Sikkema JM, Franx A, Bruinse HW, van der Wijk NG, de Valk HW, Nikkels PG. Placental pathology in early onset pre-eclampsia and intra-uterine growth restriction in women with and without thrombophilia. Placenta 2002;23:337-342.
    • (2002) Placenta , vol.23 , pp. 337-342
    • Sikkema, J.M.1    Franx, A.2    Bruinse, H.W.3    van der Wijk, N.G.4    de Valk, H.W.5    Nikkels, P.G.6
  • 3
    • 47349100695 scopus 로고    scopus 로고
    • Histologic lesions of the placenta: Villi, fetal stem arteries, intervillous spcae and maternal arteries in decidua
    • 2nd ed. London: Taylor Francis;
    • Faye-Petersen OM, Heller DS, Joshi VV. Histologic lesions of the placenta: villi, fetal stem arteries, intervillous spcae and maternal arteries in decidua. The Handbook of Placental Pathology. 2nd ed. London: Taylor Francis; 2006. pp 53-79.
    • (2006) The Handbook of Placental Pathology , pp. 53-79
    • Faye-Petersen, O.M.1    Heller, D.S.2    Joshi, V.V.3
  • 6
    • 0242593789 scopus 로고    scopus 로고
    • The frequency and severity of placental findings in women with preeclampsia are gestational age dependent
    • Moldenhauer JS, Stanek J, Warshak C, Khoury J, Sibai B. The frequency and severity of placental findings in women with preeclampsia are gestational age dependent. Am J Obstet Gynecol 2003;189:1173-1177.
    • (2003) Am J Obstet Gynecol , vol.189 , pp. 1173-1177
    • Moldenhauer, J.S.1    Stanek, J.2    Warshak, C.3    Khoury, J.4    Sibai, B.5
  • 8
    • 17044420868 scopus 로고    scopus 로고
    • Placental diagnostic criteria and clinical correlation - a workshop report
    • Redline RW, Heller D, Keating S, Kingdom J. Placental diagnostic criteria and clinical correlation - a workshop report. Placenta 2005;26(Suppl. A):S114-S117.
    • (2005) Placenta , vol.26 , Issue.SUPPL. A
    • Redline, R.W.1    Heller, D.2    Keating, S.3    Kingdom, J.4
  • 9
    • 0030981132 scopus 로고    scopus 로고
    • Markers of intravascular coagulation and fibrinolysis in preeclampsia: Association with intrauterine growth retardation
    • Schjetlein R, Haugen G, Wisloff F. Markers of intravascular coagulation and fibrinolysis in preeclampsia: association with intrauterine growth retardation. Acta Obstet Gynecol Scand 1997;76:541-546.
    • (1997) Acta Obstet Gynecol Scand , vol.76 , pp. 541-546
    • Schjetlein, R.1    Haugen, G.2    Wisloff, F.3
  • 10
    • 0027312177 scopus 로고
    • Evaluation of six markers of haemostatic system in normal pregnancy and pregnancy complicated by hypertension or pre-eclampsia
    • Cadroy Y, Grandjean H, Pichon J, Desprats R, Berrebi A, Fournie A, Boneu B. Evaluation of six markers of haemostatic system in normal pregnancy and pregnancy complicated by hypertension or pre-eclampsia. Br J Obstet Gynaecol 1993;100:416-420.
    • (1993) Br J Obstet Gynaecol , vol.100 , pp. 416-420
    • Cadroy, Y.1    Grandjean, H.2    Pichon, J.3    Desprats, R.4    Berrebi, A.5    Fournie, A.6    Boneu, B.7
  • 12
    • 0022221113 scopus 로고    scopus 로고
    • Stenberg PE, McEver RP, Shuman MA, Jacques YV, Bainton DF. A platelet alpha-granule membrane protein (GMP-140) is expressed on the plasma membrane after activation. J Cell Biol 1985;101:880-886.
    • Stenberg PE, McEver RP, Shuman MA, Jacques YV, Bainton DF. A platelet alpha-granule membrane protein (GMP-140) is expressed on the plasma membrane after activation. J Cell Biol 1985;101:880-886.
  • 14
    • 0027123107 scopus 로고
    • Molecular and cellular biology of blood coagulation
    • Furie B, Furie BC. Molecular and cellular biology of blood coagulation. N Engl J Med 1992;326:800-806.
    • (1992) N Engl J Med , vol.326 , pp. 800-806
    • Furie, B.1    Furie, B.C.2
  • 15
    • 0027367669 scopus 로고
    • Introduction: Blood coagulation
    • Mann KG, Lorand L. Introduction: blood coagulation. Methods Enzymol 1993;222:1-10.
    • (1993) Methods Enzymol , vol.222 , pp. 1-10
    • Mann, K.G.1    Lorand, L.2
  • 16
    • 0242585716 scopus 로고    scopus 로고
    • Blood coagulation
    • Dahlback B. Blood coagulation. Lancet 2000;355:1627-1632.
    • (2000) Lancet , vol.355 , pp. 1627-1632
    • Dahlback, B.1
  • 17
    • 0141707850 scopus 로고    scopus 로고
    • Thrombin and fibrinolysis
    • Nesheim M. Thrombin and fibrinolysis. Chest 2003;124:33S-39S.
    • (2003) Chest , vol.124
    • Nesheim, M.1
  • 18
    • 0024391784 scopus 로고
    • Stimulated secretion of endothelial von Willebrand factor is accompanied by rapid redistribution to the cell surface of the intracellular granule membrane protein GMP-140
    • Hattori R, Hamilton KK, Fugate RD, McEver RP, Sims PJ. Stimulated secretion of endothelial von Willebrand factor is accompanied by rapid redistribution to the cell surface of the intracellular granule membrane protein GMP-140. J Biol Chem 1989;264:7768-7771.
    • (1989) J Biol Chem , vol.264 , pp. 7768-7771
    • Hattori, R.1    Hamilton, K.K.2    Fugate, R.D.3    McEver, R.P.4    Sims, P.J.5
  • 19
    • 0028121374 scopus 로고
    • Regulation of vascular endothelial barrier function
    • Lum H, Malik AB. Regulation of vascular endothelial barrier function. Am J Physiol 1994;267:L223-L241.
    • (1994) Am J Physiol , vol.267
    • Lum, H.1    Malik, A.B.2
  • 21
    • 0020570701 scopus 로고
    • Monocyte chemotaxis: Stimulation by specific exosite region in thrombin
    • Bar-Shavit R, Kahn A, Wilner GD, Fenton JW. Monocyte chemotaxis: stimulation by specific exosite region in thrombin. Science 1983;220:728-731.
    • (1983) Science , vol.220 , pp. 728-731
    • Bar-Shavit, R.1    Kahn, A.2    Wilner, G.D.3    Fenton, J.W.4
  • 22
    • 0022470963 scopus 로고
    • Thrombin-induced chemotaxis and aggregation of neutrophils
    • Bizios R, Lai L, Fenton JW, Malik AB. Thrombin-induced chemotaxis and aggregation of neutrophils. J Cell Physiol 1986;128:485-490.
    • (1986) J Cell Physiol , vol.128 , pp. 485-490
    • Bizios, R.1    Lai, L.2    Fenton, J.W.3    Malik, A.B.4
  • 23
    • 0024230860 scopus 로고
    • The specific binding of thrombin to human polymorphonuclear leucocytes
    • Sonne O. The specific binding of thrombin to human polymorphonuclear leucocytes. Scand J Clin Lab Invest 1988;48:831-838.
    • (1988) Scand J Clin Lab Invest , vol.48 , pp. 831-838
    • Sonne, O.1
  • 24
    • 0026705071 scopus 로고
    • A role for alpha-thrombin in polymorphonuclear leukocyte recruitment during inflammation
    • Drake WT, Issekutz AC. A role for alpha-thrombin in polymorphonuclear leukocyte recruitment during inflammation. Semin Thromb Hemost 1992;18:333-340.
    • (1992) Semin Thromb Hemost , vol.18 , pp. 333-340
    • Drake, W.T.1    Issekutz, A.C.2
  • 25
    • 0026462843 scopus 로고
    • Thrombin enhancement of interleukin-1 and tumor necrosis factor-alpha induced polymorphonuclear leukocyte migration
    • Drake WT, Lopes NN, Fenton JW, Issekutz AC. Thrombin enhancement of interleukin-1 and tumor necrosis factor-alpha induced polymorphonuclear leukocyte migration. Lab Invest 1992;67:617-627.
    • (1992) Lab Invest , vol.67 , pp. 617-627
    • Drake, W.T.1    Lopes, N.N.2    Fenton, J.W.3    Issekutz, A.C.4
  • 27
    • 33847613816 scopus 로고    scopus 로고
    • Inflammation and hemostasis: A bidirectional interaction
    • Franchini M, Veneri D, Lippi G. Inflammation and hemostasis: a bidirectional interaction. Clin Lab 2007;53:63-67.
    • (2007) Clin Lab , vol.53 , pp. 63-67
    • Franchini, M.1    Veneri, D.2    Lippi, G.3
  • 28
    • 0031744875 scopus 로고    scopus 로고
    • Proteinase-activated receptors: Novel mechanisms of signaling by serine proteases
    • Dery O, Corvera CU, Steinhoff M, Bunnett NW. Proteinase-activated receptors: novel mechanisms of signaling by serine proteases. Am J Physiol 1998;274:C1429-C1452.
    • (1998) Am J Physiol , vol.274
    • Dery, O.1    Corvera, C.U.2    Steinhoff, M.3    Bunnett, N.W.4
  • 29
    • 0032748545 scopus 로고    scopus 로고
    • Protease-activated receptors and platelet function
    • Coughlin SR. Protease-activated receptors and platelet function. Thromb Haemost 1999;82:353-356.
    • (1999) Thromb Haemost , vol.82 , pp. 353-356
    • Coughlin, S.R.1
  • 30
    • 0034648757 scopus 로고    scopus 로고
    • Thrombin signalling and protease-activated receptors
    • Coughlin SR. Thrombin signalling and protease-activated receptors. Nature 2000;407:258-264.
    • (2000) Nature , vol.407 , pp. 258-264
    • Coughlin, S.R.1
  • 31
    • 0034921205 scopus 로고    scopus 로고
    • Protease-activated receptors in vascular biology
    • Coughlin SR. Protease-activated receptors in vascular biology. Thromb Haemost 2001;86:298-307.
    • (2001) Thromb Haemost , vol.86 , pp. 298-307
    • Coughlin, S.R.1
  • 32
    • 33846541231 scopus 로고    scopus 로고
    • Protease activated receptors: Clinical relevance to hemostasis and inflammation
    • Landis RC. Protease activated receptors: clinical relevance to hemostasis and inflammation. Hematol Oncol Clin North Am 2007;21:103-113.
    • (2007) Hematol Oncol Clin North Am , vol.21 , pp. 103-113
    • Landis, R.C.1
  • 33
    • 0030032791 scopus 로고    scopus 로고
    • Cellular consequences of thrombin-receptor activation
    • Grand RJ, Turnell AS, Grabham PW. Cellular consequences of thrombin-receptor activation. Biochem J 1996;313(Pt 2):353-368.
    • (1996) Biochem J , vol.313 , Issue.PART 2 , pp. 353-368
    • Grand, R.J.1    Turnell, A.S.2    Grabham, P.W.3
  • 34
    • 0035952643 scopus 로고    scopus 로고
    • Protease activated receptors: Theme and variations
    • O'Brien PJ, Molino M, Kahn M, Brass LF. Protease activated receptors: theme and variations. Oncogene 2001;20:1570-1581.
    • (2001) Oncogene , vol.20 , pp. 1570-1581
    • O'Brien, P.J.1    Molino, M.2    Kahn, M.3    Brass, L.F.4
  • 36
    • 0026690665 scopus 로고
    • Cloned platelet thrombin receptor is necessary for thrombin-induced platelet activation
    • Hung DT, Vu TK, Wheaton VI, Ishii K, Coughlin SR. Cloned platelet thrombin receptor is necessary for thrombin-induced platelet activation. J Clin Invest 1992;89:1350-1353.
    • (1992) J Clin Invest , vol.89 , pp. 1350-1353
    • Hung, D.T.1    Vu, T.K.2    Wheaton, V.I.3    Ishii, K.4    Coughlin, S.R.5
  • 37
    • 0034581513 scopus 로고    scopus 로고
    • Thrombin regulates the expression of proangiogenic cytokines via proteolytic activation of protease-activated receptor-1
    • Naldini A, Carney DH, Pucci A, Pasquali A, Carraro F. Thrombin regulates the expression of proangiogenic cytokines via proteolytic activation of protease-activated receptor-1. Gen Pharmacol 2000;35:255-259.
    • (2000) Gen Pharmacol , vol.35 , pp. 255-259
    • Naldini, A.1    Carney, D.H.2    Pucci, A.3    Pasquali, A.4    Carraro, F.5
  • 38
    • 33747826872 scopus 로고    scopus 로고
    • Induction of IL-6 release from human T cells by PAR-1 and PAR-2 agonists
    • Li T, He S. Induction of IL-6 release from human T cells by PAR-1 and PAR-2 agonists. Immunol Cell Biol 2006;84:461-466.
    • (2006) Immunol Cell Biol , vol.84 , pp. 461-466
    • Li, T.1    He, S.2
  • 39
    • 33746449323 scopus 로고    scopus 로고
    • Induction of interleukin-6 release from monocytes by serine proteinases and its potential mechanisms
    • Li T, Wang H, He S. Induction of interleukin-6 release from monocytes by serine proteinases and its potential mechanisms. Scand J Immunol 2006;64:10-16.
    • (2006) Scand J Immunol , vol.64 , pp. 10-16
    • Li, T.1    Wang, H.2    He, S.3
  • 40
    • 2142651737 scopus 로고    scopus 로고
    • Role of protease-activated receptors in the vascular system
    • Hirano K, Kanaide H. Role of protease-activated receptors in the vascular system. J Atheroscler Thromb 2003;10:211-225.
    • (2003) J Atheroscler Thromb , vol.10 , pp. 211-225
    • Hirano, K.1    Kanaide, H.2
  • 42
    • 0030008312 scopus 로고    scopus 로고
    • Role of the thrombin receptor in development and evidence for a second receptor
    • Connolly AJ, Ishihara H, Kahn ML, Farese RV Jr, Coughlin SR. Role of the thrombin receptor in development and evidence for a second receptor. Nature 1996;381:516-519.
    • (1996) Nature , vol.381 , pp. 516-519
    • Connolly, A.J.1    Ishihara, H.2    Kahn, M.L.3    Farese Jr, R.V.4    Coughlin, S.R.5
  • 44
    • 0037783288 scopus 로고    scopus 로고
    • Extracellular mediators in atherosclerosis and thrombosis: Lessons from thrombin receptor knockout mice
    • Major CD, Santulli RJ, Derian CK, Andrade-Gordon P. Extracellular mediators in atherosclerosis and thrombosis: lessons from thrombin receptor knockout mice. Arterioscler Thromb Vasc Biol 2003;23:931-939.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 931-939
    • Major, C.D.1    Santulli, R.J.2    Derian, C.K.3    Andrade-Gordon, P.4
  • 46
    • 0141425735 scopus 로고    scopus 로고
    • Thrombin receptors and protease-activated receptor-2 in human placentation: Receptor activation mediates extravillous trophoblast invasion in vitro
    • O'Brien PJ, Koi H, Parry S, Brass LF, Strauss JF III, Wang LP, Tomaszewski JE, Christenson LK. Thrombin receptors and protease-activated receptor-2 in human placentation: receptor activation mediates extravillous trophoblast invasion in vitro. Am J Pathol 2003;163:1245-1254.
    • (2003) Am J Pathol , vol.163 , pp. 1245-1254
    • O'Brien, P.J.1    Koi, H.2    Parry, S.3    Brass, L.F.4    Strauss III, J.F.5    Wang, L.P.6    Tomaszewski, J.E.7    Christenson, L.K.8
  • 47
    • 0036342618 scopus 로고    scopus 로고
    • Expression of thrombin receptors in endothelial cells and neutrophils from normal and preeclamptic pregnancies
    • Wang Y, Gu Y, Lucas MJ. Expression of thrombin receptors in endothelial cells and neutrophils from normal and preeclamptic pregnancies. J Clin Endocrinol Metab 2002;87:3728-3734.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 3728-3734
    • Wang, Y.1    Gu, Y.2    Lucas, M.J.3
  • 51
    • 0032126662 scopus 로고    scopus 로고
    • Modified antithrombin III levels during normal pregnancy and relationship with prothrombin fragment F1 + 2 and thrombin-antithrombin complexes
    • Reber G, Amiral J, de Moerloose P. Modified antithrombin III levels during normal pregnancy and relationship with prothrombin fragment F1 + 2 and thrombin-antithrombin complexes. Thromb Res 1998;91:45-47.
    • (1998) Thromb Res , vol.91 , pp. 45-47
    • Reber, G.1    Amiral, J.2    de Moerloose, P.3
  • 52
    • 0025364585 scopus 로고
    • Thrombin-antithrombin III complex levels in normal pregnancy with hypertensive disorders and after delivery
    • Reinthaller A, Mursch-Edlmayr G, Tatra G. Thrombin-antithrombin III complex levels in normal pregnancy with hypertensive disorders and after delivery. Br J Obstet Gynaecol 1990;97:506-510.
    • (1990) Br J Obstet Gynaecol , vol.97 , pp. 506-510
    • Reinthaller, A.1    Mursch-Edlmayr, G.2    Tatra, G.3
  • 53
    • 0344589384 scopus 로고    scopus 로고
    • Generation of thrombin in blood plasma of non-pregnant and pregnant women studied through concentration of thrombin-antithrombin III complexes
    • Uszynski M. Generation of thrombin in blood plasma of non-pregnant and pregnant women studied through concentration of thrombin-antithrombin III complexes. Eur J Obstet Gynecol Reprod Biol 1997;75:127-131.
    • (1997) Eur J Obstet Gynecol Reprod Biol , vol.75 , pp. 127-131
    • Uszynski, M.1
  • 55
    • 0031968737 scopus 로고    scopus 로고
    • Blood macrophage colony-stimulating factor and thrombin-antithrombin III complex concentrations in pregnancy and preeclampsia
    • Hayashi M, Numaguchi M, Ohkubo N, Yaoi Y. Blood macrophage colony-stimulating factor and thrombin-antithrombin III complex concentrations in pregnancy and preeclampsia. Am J Med Sci 1998;315:251-257.
    • (1998) Am J Med Sci , vol.315 , pp. 251-257
    • Hayashi, M.1    Numaguchi, M.2    Ohkubo, N.3    Yaoi, Y.4
  • 56
    • 0036866908 scopus 로고    scopus 로고
    • Characterization of five marker levels of the hemostatic system and endothelial status in normotensive pregnancy and pre-eclampsia
    • Hayashi M, Inoue T, Hoshimoto K, Negishi H, Ohkura T, Inaba N. Characterization of five marker levels of the hemostatic system and endothelial status in normotensive pregnancy and pre-eclampsia. Eur J Haematol 2002;69:297-302.
    • (2002) Eur J Haematol , vol.69 , pp. 297-302
    • Hayashi, M.1    Inoue, T.2    Hoshimoto, K.3    Negishi, H.4    Ohkura, T.5    Inaba, N.6
  • 57
    • 0023190964 scopus 로고
    • Preeclampsia as chronic disseminated intravascular coagulation. Study of two parameters: Thrombin-antithrombin III complex and D-dimers
    • Kobayashi T, Terao T. Preeclampsia as chronic disseminated intravascular coagulation. Study of two parameters: thrombin-antithrombin III complex and D-dimers. Gynecol Obstet Invest 1987;24:170-178.
    • (1987) Gynecol Obstet Invest , vol.24 , pp. 170-178
    • Kobayashi, T.1    Terao, T.2
  • 62
    • 0036258709 scopus 로고    scopus 로고
    • Elevated levels of serum macrophage colony-stimulating factor in normotensive pregnancies complicated by intrauterine fetal growth restriction
    • Hayashi M, Ohkura T. Elevated levels of serum macrophage colony-stimulating factor in normotensive pregnancies complicated by intrauterine fetal growth restriction. Exp Hematol 2002;30:388-393.
    • (2002) Exp Hematol , vol.30 , pp. 388-393
    • Hayashi, M.1    Ohkura, T.2
  • 63
    • 0015274596 scopus 로고
    • Primary and secondary platelet aggregation in uraemia
    • Ballard HS, Marcus AJ. Primary and secondary platelet aggregation in uraemia. Scand J Haematol 1972;9:198-203.
    • (1972) Scand J Haematol , vol.9 , pp. 198-203
    • Ballard, H.S.1    Marcus, A.J.2
  • 66
    • 0035183392 scopus 로고    scopus 로고
    • Plasma levels of thrombin-antithrombin complexes predict preterm premature rupture of the fetal membranes
    • Rosen T, Kuczynski E, O'Neill LM, Funai EF, Lockwood CJ. Plasma levels of thrombin-antithrombin complexes predict preterm premature rupture of the fetal membranes. J Matern Fetal Med 2001;10:297-300.
    • (2001) J Matern Fetal Med , vol.10 , pp. 297-300
    • Rosen, T.1    Kuczynski, E.2    O'Neill, L.M.3    Funai, E.F.4    Lockwood, C.J.5
  • 67
    • 0033833790 scopus 로고    scopus 로고
    • The mechanisms underlying the stimulatory effects of thrombin on myometrial smooth muscle
    • Elovitz MA, Ascher-Landsberg J, Saunders T, Phillippe M. The mechanisms underlying the stimulatory effects of thrombin on myometrial smooth muscle. Am J Obstet Gynecol 2000;183:674-681.
    • (2000) Am J Obstet Gynecol , vol.183 , pp. 674-681
    • Elovitz, M.A.1    Ascher-Landsberg, J.2    Saunders, T.3    Phillippe, M.4
  • 69
    • 0036169572 scopus 로고    scopus 로고
    • Thrombin-enhanced matrix metalloproteinase-1 expression: A mechanism linking placental abruption with premature rupture of the membranes
    • Rosen T, Schatz F, Kuczynski E, Lam H, Koo AB, Lockwood CJ. Thrombin-enhanced matrix metalloproteinase-1 expression: a mechanism linking placental abruption with premature rupture of the membranes. J Matern Fetal Neonatal Med 2002;11:11-17.
    • (2002) J Matern Fetal Neonatal Med , vol.11 , pp. 11-17
    • Rosen, T.1    Schatz, F.2    Kuczynski, E.3    Lam, H.4    Koo, A.B.5    Lockwood, C.J.6
  • 70
    • 24044528534 scopus 로고    scopus 로고
    • Thrombin-dependent regulation of matrix metalloproteinase (MMP)- 9 levels in human fetal membranes
    • Stephenson CD, Lockwood CJ, Ma Y, Guller S. Thrombin-dependent regulation of matrix metalloproteinase (MMP)- 9 levels in human fetal membranes. J Matern Fetal Neonatal Med 2005;18:17-22.
    • (2005) J Matern Fetal Neonatal Med , vol.18 , pp. 17-22
    • Stephenson, C.D.1    Lockwood, C.J.2    Ma, Y.3    Guller, S.4
  • 71
    • 0031825025 scopus 로고    scopus 로고
    • Normal pregnancy and preeclampsia both produce inflammatory changes in peripheral blood leukocytes akin to those of sepsis
    • Sacks GP, Studena K, Sargent K, Redman CW. Normal pregnancy and preeclampsia both produce inflammatory changes in peripheral blood leukocytes akin to those of sepsis. Am J Obstet Gynecol 1998;179:80-86.
    • (1998) Am J Obstet Gynecol , vol.179 , pp. 80-86
    • Sacks, G.P.1    Studena, K.2    Sargent, K.3    Redman, C.W.4
  • 72
    • 0036097618 scopus 로고    scopus 로고
    • Normal pregnancy is associated with peripheral leukocyte activation
    • Luppi P, Haluszczak C, Trucco M, Deloia JA. Normal pregnancy is associated with peripheral leukocyte activation. Am J Reprod Immunol 2002;47:72-81.
    • (2002) Am J Reprod Immunol , vol.47 , pp. 72-81
    • Luppi, P.1    Haluszczak, C.2    Trucco, M.3    Deloia, J.A.4
  • 75
    • 35348965534 scopus 로고    scopus 로고
    • Placental cytokines and preeclampsia
    • Keelan JA, Mitchell MD. Placental cytokines and preeclampsia. Front Biosci 2007;12:2706-2727.
    • (2007) Front Biosci , vol.12 , pp. 2706-2727
    • Keelan, J.A.1    Mitchell, M.D.2
  • 76
    • 0032957844 scopus 로고    scopus 로고
    • Preeclampsia: An excessive maternal inflammatory response to pregnancy
    • Redman CW, Sacks GP, Sargent IL. Preeclampsia: an excessive maternal inflammatory response to pregnancy. Am J Obstet Gynecol 1999;180:499-506.
    • (1999) Am J Obstet Gynecol , vol.180 , pp. 499-506
    • Redman, C.W.1    Sacks, G.P.2    Sargent, I.L.3
  • 77
    • 0033795740 scopus 로고    scopus 로고
    • Lipid-mediated endothelial dysfunction: A common factor to preeclampsia and chronic vascular disease
    • Gratacos E. Lipid-mediated endothelial dysfunction: a common factor to preeclampsia and chronic vascular disease. Eur J Obstet Gynecol Reprod Biol 2000;92:63-66.
    • (2000) Eur J Obstet Gynecol Reprod Biol , vol.92 , pp. 63-66
    • Gratacos, E.1
  • 78
    • 0035693703 scopus 로고    scopus 로고
    • The relationship between hemodynamics and inflammatory activation in women at risk for preeclampsia
    • Carr DB, McDonald GB, Brateng D, Desai M, Thach CT, Easterling TR. The relationship between hemodynamics and inflammatory activation in women at risk for preeclampsia. Obstet Gynecol 2001;98:1109-1116.
    • (2001) Obstet Gynecol , vol.98 , pp. 1109-1116
    • Carr, D.B.1    McDonald, G.B.2    Brateng, D.3    Desai, M.4    Thach, C.T.5    Easterling, T.R.6
  • 82
    • 0141838133 scopus 로고    scopus 로고
    • Pre-eclampsia, the placenta and the maternal systemic inflammatory response - a review
    • Redman CW, Sargent IL. Pre-eclampsia, the placenta and the maternal systemic inflammatory response - a review. Placenta 2003;24(Suppl. A):S21-S27.
    • (2003) Placenta , vol.24 , Issue.SUPPL. A
    • Redman, C.W.1    Sargent, I.L.2
  • 83
  • 84
    • 0042669785 scopus 로고    scopus 로고
    • Th1/Th2 balance in preeclampsia
    • Saito S, Sakai M. Th1/Th2 balance in preeclampsia. J Reprod Immunol 2003;59:161-173.
    • (2003) J Reprod Immunol , vol.59 , pp. 161-173
    • Saito, S.1    Sakai, M.2
  • 87
    • 20444409135 scopus 로고    scopus 로고
    • Latest advances in understanding preeclampsia
    • Redman CW, Sargent IL. Latest advances in understanding preeclampsia. Science 2005;308:1592-1594.
    • (2005) Science , vol.308 , pp. 1592-1594
    • Redman, C.W.1    Sargent, I.L.2
  • 88
    • 32044450078 scopus 로고    scopus 로고
    • Monocytes of preeclamptic women spontaneously synthesize pro-inflammatory cytokines
    • Luppi P, Deloia JA. Monocytes of preeclamptic women spontaneously synthesize pro-inflammatory cytokines. Clin Immunol 2006;118:268-275.
    • (2006) Clin Immunol , vol.118 , pp. 268-275
    • Luppi, P.1    Deloia, J.A.2
  • 90
    • 33745865210 scopus 로고    scopus 로고
    • Anti-inflammatory interventions in pregnancy: Now and the future
    • Elovitz MA. Anti-inflammatory interventions in pregnancy: now and the future. Semin Fetal Neonatal Med 2006;11:327-332.
    • (2006) Semin Fetal Neonatal Med , vol.11 , pp. 327-332
    • Elovitz, M.A.1
  • 95
    • 0020550530 scopus 로고
    • Analysis of mononuclear cell subsets in pregnancies with intrauterine growth retardation. Evidence of chronic B-lymphocyte activation
    • Selvaggi L, Lucivero G, Iannone A, dell'Osso A, Loverro G, Antonaci S, Bonomo L, Bettocchi S. Analysis of mononuclear cell subsets in pregnancies with intrauterine growth retardation. Evidence of chronic B-lymphocyte activation. J Perinat Med 1983;11:213-217.
    • (1983) J Perinat Med , vol.11 , pp. 213-217
    • Selvaggi, L.1    Lucivero, G.2    Iannone, A.3    dell'Osso, A.4    Loverro, G.5    Antonaci, S.6    Bonomo, L.7    Bettocchi, S.8
  • 96
    • 0021833191 scopus 로고
    • Serum growth-promoting activity in human newborns. Relationship of thymidine activity with birth weight and the length of gestation
    • Bozzola M, Chirico G, Chiara A, Gasparoni A, Schimpff RM. Serum growth-promoting activity in human newborns. Relationship of thymidine activity with birth weight and the length of gestation. Acta Paediatr Scand 1985;74:534-538.
    • (1985) Acta Paediatr Scand , vol.74 , pp. 534-538
    • Bozzola, M.1    Chirico, G.2    Chiara, A.3    Gasparoni, A.4    Schimpff, R.M.5
  • 98
    • 33748450585 scopus 로고    scopus 로고
    • Complement activation induces dysregulation of angiogenic factors and causes fetal rejection and growth restriction
    • Girardi G, Yarilin D, Thurman JM, Holers VM, Salmon JE. Complement activation induces dysregulation of angiogenic factors and causes fetal rejection and growth restriction. J Exp Med 2006;203:2165-2175.
    • (2006) J Exp Med , vol.203 , pp. 2165-2175
    • Girardi, G.1    Yarilin, D.2    Thurman, J.M.3    Holers, V.M.4    Salmon, J.E.5
  • 99
    • 13844296844 scopus 로고    scopus 로고
    • A cohort study found that white blood cell count and endocrine markers predicted preterm birth in symptomatic women
    • Campbell MK, Challis JR, DaSilva O, Bocking AD. A cohort study found that white blood cell count and endocrine markers predicted preterm birth in symptomatic women. J Clin Epidemiol 2005;58:304-310.
    • (2005) J Clin Epidemiol , vol.58 , pp. 304-310
    • Campbell, M.K.1    Challis, J.R.2    DaSilva, O.3    Bocking, A.D.4
  • 100
    • 0025940386 scopus 로고
    • Neutrophil attractant/activating peptide-1/interleukin-8 in term and preterm parturition
    • Romero R, Ceska M, Avila C, Mazor M, Behnke E, Lindley I. Neutrophil attractant/activating peptide-1/interleukin-8 in term and preterm parturition. Am J Obstet Gynecol 1991;165:813-820.
    • (1991) Am J Obstet Gynecol , vol.165 , pp. 813-820
    • Romero, R.1    Ceska, M.2    Avila, C.3    Mazor, M.4    Behnke, E.5    Lindley, I.6
  • 101
    • 0024636255 scopus 로고
    • Prostaglandins, inflammation, and preterm labor
    • Bry K, Hallman M. Prostaglandins, inflammation, and preterm labor. J Perinatol 1989;9:60-65.
    • (1989) J Perinatol , vol.9 , pp. 60-65
    • Bry, K.1    Hallman, M.2
  • 103
    • 23944464960 scopus 로고    scopus 로고
    • Soto E, Romero R, Richani K, Espinoza J, Nien JK, Chaiworapongsa T, Santolaya-Forgas J, Edwin SS, Mazor M. Anaphylatoxins in preterm and term labor. J Perinat Med 2005;33:306-313.
    • Soto E, Romero R, Richani K, Espinoza J, Nien JK, Chaiworapongsa T, Santolaya-Forgas J, Edwin SS, Mazor M. Anaphylatoxins in preterm and term labor. J Perinat Med 2005;33:306-313.
  • 105
    • 0037527953 scopus 로고    scopus 로고
    • Maternal serum interleukin-6, interleukin-8, tumor necrosis factor-alpha and interferon-gamma in preterm labor
    • Bahar AM, Ghalib HW, Moosa RA, Zaki ZM, Thomas C, Nabri OA. Maternal serum interleukin-6, interleukin-8, tumor necrosis factor-alpha and interferon-gamma in preterm labor. Acta Obstet Gynecol Scand 2003;82:543-549.
    • (2003) Acta Obstet Gynecol Scand , vol.82 , pp. 543-549
    • Bahar, A.M.1    Ghalib, H.W.2    Moosa, R.A.3    Zaki, Z.M.4    Thomas, C.5    Nabri, O.A.6
  • 106
    • 20744450270 scopus 로고    scopus 로고
    • Preterm delivery predicted by soluble CD163 and CRP in women with symptoms of preterm delivery
    • Vogel I, Grove J, Thorsen P, Moestrup SK, Uldbjerg N, Moller HJ. Preterm delivery predicted by soluble CD163 and CRP in women with symptoms of preterm delivery. BJOG 2005;112:737-742.
    • (2005) BJOG , vol.112 , pp. 737-742
    • Vogel, I.1    Grove, J.2    Thorsen, P.3    Moestrup, S.K.4    Uldbjerg, N.5    Moller, H.J.6
  • 108
    • 0036817354 scopus 로고    scopus 로고
    • The changes of circulating lymphocyte sub-populations in women with preterm labour: A case-controlled study
    • Sendag F, Itil IM, Terek MC, Yilmaz H. The changes of circulating lymphocyte sub-populations in women with preterm labour: a case-controlled study. Aust N Z J Obstet Gynaecol 2002;42:358-361.
    • (2002) Aust N Z J Obstet Gynaecol , vol.42 , pp. 358-361
    • Sendag, F.1    Itil, I.M.2    Terek, M.C.3    Yilmaz, H.4
  • 114
    • 0033532076 scopus 로고    scopus 로고
    • Thrombin induces proteinase-activated receptor-1 gene expression in endothelial cells via activation of Gi-linked Ras/mitogen- activated protein kinase pathway
    • Ellis CA, Malik AB, Gilchrist A, Hamm H, Sandoval R, Voyno-Yasenetskaya T, Tiruppathi C. Thrombin induces proteinase-activated receptor-1 gene expression in endothelial cells via activation of Gi-linked Ras/mitogen- activated protein kinase pathway. J Biol Chem 1999;274:13718-13727.
    • (1999) J Biol Chem , vol.274 , pp. 13718-13727
    • Ellis, C.A.1    Malik, A.B.2    Gilchrist, A.3    Hamm, H.4    Sandoval, R.5    Voyno-Yasenetskaya, T.6    Tiruppathi, C.7
  • 117
    • 0037667751 scopus 로고    scopus 로고
    • Activation of mast cells induced by agonists of proteinase-activated receptors under normal conditions and during acute inflammation in rats
    • Dugina TN, Kiseleva EV, Glusa E, Strukova SM. Activation of mast cells induced by agonists of proteinase-activated receptors under normal conditions and during acute inflammation in rats. Eur J Pharmacol 2003;471:141-147.
    • (2003) Eur J Pharmacol , vol.471 , pp. 141-147
    • Dugina, T.N.1    Kiseleva, E.V.2    Glusa, E.3    Strukova, S.M.4
  • 118
    • 0036533649 scopus 로고    scopus 로고
    • Activation of protease-activated receptor (PAR)-1, PAR-2, and PAR-4 stimulates IL-6, IL-8, and prostaglandin E2 release from human respiratory epithelial cells
    • Asokananthan N, Graham PT, Fink J, Knight DA, Bakker AJ, McWilliam AS, Thompson PJ, Stewart GA. Activation of protease-activated receptor (PAR)-1, PAR-2, and PAR-4 stimulates IL-6, IL-8, and prostaglandin E2 release from human respiratory epithelial cells. J Immunol 2002;168:3577-3585.
    • (2002) J Immunol , vol.168 , pp. 3577-3585
    • Asokananthan, N.1    Graham, P.T.2    Fink, J.3    Knight, D.A.4    Bakker, A.J.5    McWilliam, A.S.6    Thompson, P.J.7    Stewart, G.A.8
  • 120
    • 0041328272 scopus 로고    scopus 로고
    • The agonist of the protease-activated receptor-1 (PAR) but not PAR3 mimics thrombin-induced vascular endothelial growth factor release in human smooth muscle cells
    • Arisato T, Sarker KP, Kawahara K, Nakata M, Hashiguchi T, Osame M, Kitajima I, Maruyama I. The agonist of the protease-activated receptor-1 (PAR) but not PAR3 mimics thrombin-induced vascular endothelial growth factor release in human smooth muscle cells. Cell Mol Life Sci 2003;60:1716-1724.
    • (2003) Cell Mol Life Sci , vol.60 , pp. 1716-1724
    • Arisato, T.1    Sarker, K.P.2    Kawahara, K.3    Nakata, M.4    Hashiguchi, T.5    Osame, M.6    Kitajima, I.7    Maruyama, I.8
  • 121
    • 0034614895 scopus 로고    scopus 로고
    • Protease-activated receptor 1 mediates thrombin-dependent, cell-mediated renal inflammation in crescentic glomerulonephritis
    • Cunningham MA, Rondeau E, Chen X, Coughlin SR, Holdsworth SR, Tipping PG. Protease-activated receptor 1 mediates thrombin-dependent, cell-mediated renal inflammation in crescentic glomerulonephritis. J Exp Med 2000;191:455-462.
    • (2000) J Exp Med , vol.191 , pp. 455-462
    • Cunningham, M.A.1    Rondeau, E.2    Chen, X.3    Coughlin, S.R.4    Holdsworth, S.R.5    Tipping, P.G.6
  • 122
    • 0035979691 scopus 로고    scopus 로고
    • A role for thrombin receptor signaling in endothelial cells during embryonic development
    • Griffin CT, Srinivasan Y, Zheng YW, Huang W, Coughlin SR. A role for thrombin receptor signaling in endothelial cells during embryonic development. Science 2001;293:1666-1670.
    • (2001) Science , vol.293 , pp. 1666-1670
    • Griffin, C.T.1    Srinivasan, Y.2    Zheng, Y.W.3    Huang, W.4    Coughlin, S.R.5
  • 124
  • 126
    • 8644254439 scopus 로고    scopus 로고
    • Angiogenic imbalance in the pathophysiology of preeclampsia: Newer insights
    • Bdolah Y, Sukhatme VP, Karumanchi SA. Angiogenic imbalance in the pathophysiology of preeclampsia: newer insights. Semin Nephrol 2004;24:548-556.
    • (2004) Semin Nephrol , vol.24 , pp. 548-556
    • Bdolah, Y.1    Sukhatme, V.P.2    Karumanchi, S.A.3
  • 127
    • 9244257839 scopus 로고    scopus 로고
    • Hypoxia and sFlt-1 in preeclampsia: The "chicken-and-egg" question
    • Karumanchi SA, Bdolah Y. Hypoxia and sFlt-1 in preeclampsia: the "chicken-and-egg" question. Endocrinology 2004;145:4835-4837.
    • (2004) Endocrinology , vol.145 , pp. 4835-4837
    • Karumanchi, S.A.1    Bdolah, Y.2
  • 132
    • 26244444083 scopus 로고    scopus 로고
    • Recent advances in understanding of preeclampsia
    • Bdolah Y, Karumanchi SA, Sachs BP. Recent advances in understanding of preeclampsia. Croat Med J 2005;46:728-736.
    • (2005) Croat Med J , vol.46 , pp. 728-736
    • Bdolah, Y.1    Karumanchi, S.A.2    Sachs, B.P.3
  • 133
    • 27444433714 scopus 로고    scopus 로고
    • Circulating angiogenic factors in the pathogenesis and prediction of preeclampsia
    • Lam C, Lim KH, Karumanchi SA. Circulating angiogenic factors in the pathogenesis and prediction of preeclampsia. Hypertension 2005;46:1077-1085.
    • (2005) Hypertension , vol.46 , pp. 1077-1085
    • Lam, C.1    Lim, K.H.2    Karumanchi, S.A.3
  • 135
    • 17844372519 scopus 로고    scopus 로고
    • Soluble Fms-like tyrosine kinase 1 and endothelial dysfunction in the pathogenesis of preeclampsia
    • Maynard SE, Venkatesha S, Thadhani R, Karumanchi SA. Soluble Fms-like tyrosine kinase 1 and endothelial dysfunction in the pathogenesis of preeclampsia. Pediatr Res 2005;57:1R-7R.
    • (2005) Pediatr Res , vol.57
    • Maynard, S.E.1    Venkatesha, S.2    Thadhani, R.3    Karumanchi, S.A.4
  • 136
    • 21444452423 scopus 로고    scopus 로고
    • Extra-placental expression of vascular endothelial growth factor receptor-1, (Flt-1) and soluble Flt-1 (sFlt-1), by peripheral blood mononuclear cells (PBMCs) in normotensive and preeclamptic pregnant women
    • Rajakumar A, Michael HM, Rajakumar PA, Shibata E, Hubel CA, Karumanchi SA, Thadhani R, Wolf M, Harger G, Markovic N. Extra-placental expression of vascular endothelial growth factor receptor-1, (Flt-1) and soluble Flt-1 (sFlt-1), by peripheral blood mononuclear cells (PBMCs) in normotensive and preeclamptic pregnant women. Placenta 2005;26:563-573.
    • (2005) Placenta , vol.26 , pp. 563-573
    • Rajakumar, A.1    Michael, H.M.2    Rajakumar, P.A.3    Shibata, E.4    Hubel, C.A.5    Karumanchi, S.A.6    Thadhani, R.7    Wolf, M.8    Harger, G.9    Markovic, N.10
  • 138
    • 18044370643 scopus 로고    scopus 로고
    • Circulating angiogenic factors in preeclampsia
    • Levine RJ, Karumanchi SA. Circulating angiogenic factors in preeclampsia. Clin Obstet Gynecol 2005;48:372-386.
    • (2005) Clin Obstet Gynecol , vol.48 , pp. 372-386
    • Levine, R.J.1    Karumanchi, S.A.2
  • 142
    • 33645895289 scopus 로고    scopus 로고
    • Serum sFlt1 concentration during preeclampsia and mid trimester blood pressure in healthy nulliparous women
    • Levine RJ, Qian C, Maynard SE, Yu KF, Epstein FH, Karumanchi SA. Serum sFlt1 concentration during preeclampsia and mid trimester blood pressure in healthy nulliparous women. Am J Obstet Gynecol 2006;194:1034-1041.
    • (2006) Am J Obstet Gynecol , vol.194 , pp. 1034-1041
    • Levine, R.J.1    Qian, C.2    Maynard, S.E.3    Yu, K.F.4    Epstein, F.H.5    Karumanchi, S.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.