Structure-activity models of oral clearance, cytotoxicity, and LD50: A screen for promising anticancer compounds

BMC Pharmacology

Volumn 8, Issue , 2008, Pages

  Boik, John C ^a   Newman, Robert A ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRAQUINONE; ANTINEOPLASTIC AGENT; FLAVONOID; NATURAL PRODUCT;

ALGORITHM; ARTICLE; CANCER CELL; DATA BASE; DRUG ACTIVITY; DRUG CLEARANCE; DRUG CYTOTOXICITY; DRUG IDENTIFICATION; HUMAN; HUMAN CELL; IN VITRO STUDY; LD 50; QUANTITATIVE STRUCTURE ACTIVITY RELATION; ANIMAL; BIOLOGICAL MODEL; CHEMISTRY; COMPARATIVE STUDY; DRUG EFFECT; DRUG SCREENING; METABOLIC CLEARANCE RATE; METHODOLOGY; ORAL DRUG ADMINISTRATION; PHYSIOLOGY; RAT; TUMOR CELL LINE;

ADMINISTRATION, ORAL; ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DRUG EVALUATION, PRECLINICAL; HUMANS; LETHAL DOSE 50; METABOLIC CLEARANCE RATE; MODELS, BIOLOGICAL; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; RATS;

EID: 47349088057     PISSN: None     EISSN: 14712210     Source Type: Journal    
DOI: 10.1186/1471-2210-8-12     Document Type: Article

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