Bioavailability and pharmacokinetic disposition of tacrine in elderly patients with Alzheimer's disease

Journal of Psychiatry and Neuroscience

Volumn 21, Issue 5, 1996, Pages 334-339

  Sitar, Daniel S ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

Author keywords

Alzheimer's disease; pharmacokinetics; tacrine

Indexed keywords

TACRINE;

AGED; ALZHEIMER DISEASE; AREA UNDER THE CURVE; ARTICLE; BIOAVAILABILITY; CLINICAL ARTICLE; DRUG BLOOD LEVEL; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG URINE LEVEL; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; MALE; ORAL DRUG ADMINISTRATION; PHARMACODYNAMICS;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; BIOLOGICAL AVAILABILITY; CROSS-OVER STUDIES; FEMALE; HUMANS; MALE; MIDDLE AGED; NOOTROPIC AGENTS; TACRINE;

EID: 0030449513     PISSN: 11804882     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (2)

1. Ahlin A, Adern A, Junthe T, Ohman G, Nyback H. 1992. Pharmacokinetics of tetrahydroaminoacridine: relations to clinical and biochemical effects in Alzheimer's patients. Int Clin Psychopharmacol 7:29-36.
2. Ahlin A, Hassan M, Junthe T, Nyback H. 1994. Tacrine in Alzheimer's disease: pharmacokinetic and clinical comparison of oral and rectal administration. Int Clin Psychopharmacol 9:263-70.