A topological sub-structural approach for predicting human intestinal absorption of drugs

European Journal of Medicinal Chemistry

Volumn 39, Issue 11, 2004, Pages 905-916

  Pérez, Miguel Angel Cabrera ^a   Sanz, Marival Bermejo ^b   Torres, Liliana Ramos ^a   Évalos, Ricardo Grau ^a   González, Maykel Pérez ^a   Díaz, Humberto González ^a  

^a CENTRAL UNIVERSITY OF LAS VILLAS   (Cuba)

^b UNIVERSITY OF VALENCIA   (Spain)

Author keywords

Discriminant analysis; In silico; Intestinal absorption; Sub structural approach

Indexed keywords

ALPRENOLOL; AZTREONAM; BETAXOLOL; BUMETANIDE; CEFADROXIL; CHLORAMPHENICOL; CHLORPHENESIN; CLONIDINE; DESIPRAMINE; DIAZEPAM; FLUCONAZOLE; GUANFACINE; HYDROCORTISONE; IBUPROFEN; KETOPROFEN; NAPROXEN; OFLOXACIN; ONDANSETRON; OXAZEPAM; PEFLOXACIN; PHENAZONE; PRACTOLOL; PREDNISOLONE; SULBACTAM; SULTOPRIDE; TENIDAP; TESTOSTERONE; TRIMETHOPRIM; UNINDEXED DRUG; WARFARIN;

ARTICLE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; INTESTINE ABSORPTION; PREDICTION; QUANTITATIVE STRUCTURE ACTIVITY RELATION; VALIDATION PROCESS;

BIOLOGICAL AVAILABILITY; HUMANS; INTESTINAL ABSORPTION; INTESTINAL MUCOSA; MODELS, THEORETICAL; PHARMACEUTICAL PREPARATIONS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 6344252814     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejmech.2004.06.012     Document Type: Article

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