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Volumn 57, Issue 2, 2008, Pages 75-83

Advances in genomic research on hepatitis C virus with a useful tool, replicon system

Author keywords

Hepatitis C virus; Lipid raft; Rb; Replicon; VX950

Indexed keywords

4' AZIDOCYTIDINE 2',3',5' TRIISOBUTYRATE; 5 CYCLOPROPYL 2 (4 FLUOROPHENYL) 6 [N (2 HYDROXYETHYL)METHANESULFONAMIDO] N METHYLBENZOFURAN 3 CARBOXAMIDE; A 689; A 831; A 837093; ANTIVIRUS AGENT; BILB 1941; CASTANOSPERMINE 6 BUTYRATE; CYCLOSPORIN A [4 N METHYLISOLEUCINE]; DEBIO 25; E2 MONOCLONAL ANTIBODY; GS 9190; HEPATITIS C ANTIBODY; INTERFERON; ITMN 191; MK 608; MONOCLONAL ANTIBODY; MYOCRICIN; N [3 AMINO 1 (CYCLOBUTYLMETHYL) 2,3 DIOXOPROPYL] 3 [2 (3 TERT BUTYLUREIDO) 3,3 DIMETHYL 1 OXOBUTYL] 6,6 DIMETHYL 3 AZABICYCLO[3.1.0]HEXANE 2 CARBOXAMIDE; PEGINTERFERON; PEGINTERFERON ALPHA2B; R 1656; R 7128; RIBAVIRIN; SMALL INTERFERING RNA; TELAPREVIR; TOLL LIKE RECEPTOR 9 AGONIST; UNINDEXED DRUG; VALOPICITABINE; VIRUS RNA;

EID: 47249127753     PISSN: 00229717     EISSN: 18801293     Source Type: Journal    
DOI: 10.2302/kjm.57.75     Document Type: Review
Times cited : (5)

References (69)
  • 2
    • 0028785460 scopus 로고
    • A novel sequence found at the 3′ terminus of hepatitis C virus genome
    • Tanaka T, Kato N, Cho MJ, Shimotohno K: A novel sequence found at the 3′ terminus of hepatitis C virus genome. Biochem Biophys Res Commun 1995; 215: 744-749
    • (1995) Biochem Biophys Res Commun , vol.215 , pp. 744-749
    • Tanaka, T.1    Kato, N.2    Cho, M.J.3    Shimotohno, K.4
  • 5
    • 0029161576 scopus 로고
    • Comparison of full-length sequences of interferon-sensitive and resistant hepatitis C virus 1b. Sensitivity to interferon is conferred by amino acid substitutions in the NS5A region
    • N Enomoto, I Sakuma, Y Asahina, M Kurosaki, T Murakami, C Yamamoto, N Izumi, F Marumo, C Sato: Comparison of full-length sequences of interferon-sensitive and resistant hepatitis C virus 1b. Sensitivity to interferon is conferred by amino acid substitutions in the NS5A region. J Clin Invest 1995; 96: 224-230
    • (1995) J Clin Invest , vol.96 , pp. 224-230
    • Enomoto, N.1    Sakuma, I.2    Asahina, Y.3    Kurosaki, M.4    Murakami, T.5    Yamamoto, C.6    Izumi, N.7    Marumo, F.8    Sato, C.9
  • 8
    • 0024509701 scopus 로고
    • Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome
    • Choo QL, Kuo G, Weiner AJ, Overby LR, Bradley DW, Houghton M: Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. Science 1989; 244: 359-362
    • (1989) Science , vol.244 , pp. 359-362
    • Choo, Q.L.1    Kuo, G.2    Weiner, A.J.3    Overby, L.R.4    Bradley, D.W.5    Houghton, M.6
  • 12
    • 0037370622 scopus 로고    scopus 로고
    • Efficient replication of hepatitis C virus genotype 1a RNAs in cell culture
    • Blight KJ, McKeating JA, Marcotrigiano J, Rice CM: Efficient replication of hepatitis C virus genotype 1a RNAs in cell culture. J Virol 2003; 77: 3181-3190
    • (2003) J Virol , vol.77 , pp. 3181-3190
    • Blight, K.J.1    McKeating, J.A.2    Marcotrigiano, J.3    Rice, C.M.4
  • 14
    • 0036190918 scopus 로고    scopus 로고
    • Selectable subgenomic and genome-length dicistronic RNAs derived from an infectious molecular clone of the HCV-N strain of hepatitis C virus replicate efficiently in cultured Huh7 cells
    • Ikeda M, Yi M, Li K, Lemon SM: Selectable subgenomic and genome-length dicistronic RNAs derived from an infectious molecular clone of the HCV-N strain of hepatitis C virus replicate efficiently in cultured Huh7 cells. J Virol 2002; 76: 2997-3006.
    • (2002) J Virol , vol.76 , pp. 2997-3006
    • Ikeda, M.1    Yi, M.2    Li, K.3    Lemon, S.M.4
  • 15
    • 0035157218 scopus 로고    scopus 로고
    • Mutations in hepatitis C virus RNAs conferring cell culture adaptation
    • Lohmann V, Korner F, Dobierzewska A, Bartenschlager R: Mutations in hepatitis C virus RNAs conferring cell culture adaptation. J Virol 2001; 75: 1437-1449
    • (2001) J Virol , vol.75 , pp. 1437-1449
    • Lohmann, V.1    Korner, F.2    Dobierzewska, A.3    Bartenschlager, R.4
  • 16
    • 2442659173 scopus 로고    scopus 로고
    • Polymorphism of NS5B protein relates to early clearance of hepatitis C virus by interferon plus ribavirin: A pilot study
    • Kumagai N, Takahashi N, Kinoshita M, Tsunematsu S, Tsuchimoto K, Saito H, Ishii H, Hibi T: Polymorphism of NS5B protein relates to early clearance of hepatitis C virus by interferon plus ribavirin: a pilot study. J Viral Hepat 2004; 11: 225-235
    • (2004) J Viral Hepat , vol.11 , pp. 225-235
    • Kumagai, N.1    Takahashi, N.2    Kinoshita, M.3    Tsunematsu, S.4    Tsuchimoto, K.5    Saito, H.6    Ishii, H.7    Hibi, T.8
  • 17
    • 40549128699 scopus 로고    scopus 로고
    • Possible molecular mechanism of the relationship between NS5B polymorphisms and early clearance of hepatitis C virus during interferon plus ribavirin treatment
    • Nakamura M, Saito H, Ikeda M, Tada S, Kumagai N, Kato N, Shimotohno K, Hibi T: Possible molecular mechanism of the relationship between NS5B polymorphisms and early clearance of hepatitis C virus during interferon plus ribavirin treatment. J Med Virol 2008; 80: 632-639
    • (2008) J Med Virol , vol.80 , pp. 632-639
    • Nakamura, M.1    Saito, H.2    Ikeda, M.3    Tada, S.4    Kumagai, N.5    Kato, N.6    Shimotohno, K.7    Hibi, T.8
  • 18
    • 0037370622 scopus 로고    scopus 로고
    • Efficient replication of hepatitis C virus genotype 1a RNAs in cell culture
    • Blight KJ, McKeating JA, Marcotrigiano J, Rice CM: Efficient replication of hepatitis C virus genotype 1a RNAs in cell culture. J Virol 2003; 77: 3181-3190
    • (2003) J Virol , vol.77 , pp. 3181-3190
    • Blight, K.J.1    McKeating, J.A.2    Marcotrigiano, J.3    Rice, C.M.4
  • 25
    • 0346118919 scopus 로고    scopus 로고
    • Hepatitis C virus non-structural proteins in the probable membranous compartment function in viral genome replication
    • Miyanari Y, Hijikata M, Yamaji M, Hosaka M, Takahashi H, Shimotohno K: Hepatitis C virus non-structural proteins in the probable membranous compartment function in viral genome replication. J Biol Chem 2003; 278: 50301-50308
    • (2003) J Biol Chem , vol.278 , pp. 50301-50308
    • Miyanari, Y.1    Hijikata, M.2    Yamaji, M.3    Hosaka, M.4    Takahashi, H.5    Shimotohno, K.6
  • 26
    • 0345144016 scopus 로고    scopus 로고
    • Identification of the hepatitis C virus RNA replication complex in Huh-7 cells harboring subgenomic replicons
    • Gosert R, Egger D, Lohmann V, Bartenschlager R, Blum HE, Bienz K, Moradpour D: Identification of the hepatitis C virus RNA replication complex in Huh-7 cells harboring subgenomic replicons. J Virol 2003; 77: 5487-5492
    • (2003) J Virol , vol.77 , pp. 5487-5492
    • Gosert, R.1    Egger, D.2    Lohmann, V.3    Bartenschlager, R.4    Blum, H.E.5    Bienz, K.6    Moradpour, D.7
  • 27
    • 0036204740 scopus 로고    scopus 로고
    • A positive-strand RNA virus replication complex parallels form and function of retrovirus capsids
    • Schwartz M, Chen J, Janda M, Sullivan M, den Boon J, Ahlquist P: A positive-strand RNA virus replication complex parallels form and function of retrovirus capsids. Mol Cell 2002; 9: 505-514
    • (2002) Mol Cell , vol.9 , pp. 505-514
    • Schwartz, M.1    Chen, J.2    Janda, M.3    Sullivan, M.4    den Boon, J.5    Ahlquist, P.6
  • 33
    • 11844265960 scopus 로고    scopus 로고
    • Benefit of hepatitis C virus core antigen assay in prediction of therapeutic response to interferon and ribavirin combination therapy
    • Takahashi M, Saito H, Higashimoto M, Atsukawa K, Ishii H: Benefit of hepatitis C virus core antigen assay in prediction of therapeutic response to interferon and ribavirin combination therapy. J Clin Microbiol 2005; 43: 186-191
    • (2005) J Clin Microbiol , vol.43 , pp. 186-191
    • Takahashi, M.1    Saito, H.2    Higashimoto, M.3    Atsukawa, K.4    Ishii, H.5
  • 34
    • 33947322237 scopus 로고    scopus 로고
    • Role of erythrocytes as a reservoir for ribavirin and relationship with adverse reactions in the early phase of interferon combination therapy for chronic hepatitis C virus infections
    • Saito H, Tada S, Ebinuma H, Ishii H, Kashiwazaki K, Takahashi M, Tsukada N, Nishida J, Tanaka S, Shiozaki H, Hibi T: Role of erythrocytes as a reservoir for ribavirin and relationship with adverse reactions in the early phase of interferon combination therapy for chronic hepatitis C virus infections. J Clin Microbiol 2006; 44:3562-3568
    • (2006) J Clin Microbiol , vol.44 , pp. 3562-3568
    • Saito, H.1    Tada, S.2    Ebinuma, H.3    Ishii, H.4    Kashiwazaki, K.5    Takahashi, M.6    Tsukada, N.7    Nishida, J.8    Tanaka, S.9    Shiozaki, H.10    Hibi, T.11
  • 35
    • 0142182744 scopus 로고    scopus 로고
    • Cyclosporin A suppresses replication of hepatitis C virus genome in cultured hepatocytes
    • Watashi K, Hijikata M, Hosaka M, Yamaji M, Shimotohno K: Cyclosporin A suppresses replication of hepatitis C virus genome in cultured hepatocytes. Hepatology 2003; 38:1282-1288
    • (2003) Hepatology , vol.38 , pp. 1282-1288
    • Watashi, K.1    Hijikata, M.2    Hosaka, M.3    Yamaji, M.4    Shimotohno, K.5
  • 36
    • 0037057583 scopus 로고    scopus 로고
    • Cyclosporins: Structure-activity relationships for the inhibition of the human MDR1 P-glycoprotein ABC transporter
    • Loor F, Tiberghien F, Wenandy T, Didier A, Traber R: Cyclosporins: structure-activity relationships for the inhibition of the human MDR1 P-glycoprotein ABC transporter. J Med Chem 2002; 45: 4598-4612
    • (2002) J Med Chem , vol.45 , pp. 4598-4612
    • Loor, F.1    Tiberghien, F.2    Wenandy, T.3    Didier, A.4    Traber, R.5
  • 37
    • 0346103657 scopus 로고    scopus 로고
    • Disruption of hepatitis C virus RNA replication through inhibition of host protein geranylgeranylation
    • Ye J, Wang C, Sumpter R, Jr., Brown MS, Goldstein JL, Gale M, Jr: Disruption of hepatitis C virus RNA replication through inhibition of host protein geranylgeranylation. Proc Natl Acad Sci U S A 2003; 100: 15865-15870
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 15865-15870
    • Ye, J.1    Wang, C.2    Sumpter Jr., R.3    Brown, M.S.4    Goldstein, J.L.5    Gale Jr, M.6
  • 38
    • 0038102952 scopus 로고    scopus 로고
    • Combined interferon α2b and cyclosporin A in the treatment of chronic hepatitis C: Controlled trial
    • Inoue K, Sekiyama K, Yamada M, Watanabe T, Yasuda H, Yoshiba M: Combined interferon α2b and cyclosporin A in the treatment of chronic hepatitis C: controlled trial. J Gastroenterol 2003; 38: 567-572
    • (2003) J Gastroenterol , vol.38 , pp. 567-572
    • Inoue, K.1    Sekiyama, K.2    Yamada, M.3    Watanabe, T.4    Yasuda, H.5    Yoshiba, M.6
  • 40
    • 33645911783 scopus 로고    scopus 로고
    • Evaliation of the anti-hepatitis C virus effects of cyclophilin inhibitors, cyclosporine A, and NIM 811
    • Goto K, Watashi K, Murata T, Hishiki T, Hijikata M, SHimotohno K: Evaliation of the anti-hepatitis C virus effects of cyclophilin inhibitors, cyclosporine A, and NIM 811. Biochem Biophys Res Commun 2006; 343: 879-884
    • (2006) Biochem Biophys Res Commun , vol.343 , pp. 879-884
    • Goto, K.1    Watashi, K.2    Murata, T.3    Hishiki, T.4    Hijikata, M.5    SHimotohno, K.6
  • 42
    • 33745903898 scopus 로고    scopus 로고
    • Different anti-HCV profiles of statins and their potential for combination therapy with interferon
    • Ikeda M, Abe K, Yamada M, Dansako H, Naka K, Kato N: Different anti-HCV profiles of statins and their potential for combination therapy with interferon. Hepatology 2006; 44: 117-125
    • (2006) Hepatology , vol.44 , pp. 117-125
    • Ikeda, M.1    Abe, K.2    Yamada, M.3    Dansako, H.4    Naka, K.5    Kato, N.6
  • 45
    • 0037687422 scopus 로고    scopus 로고
    • Regulation of interferon regulatory factor-3 by the hepatitis C virus serine protease
    • Foy E, Li K, Wang C, Sumpter R, Ikeda M, Lemon SM, Gale M: Regulation of interferon regulatory factor-3 by the hepatitis C virus serine protease. Science 2003; 300: 1145-1148
    • (2003) Science , vol.300 , pp. 1145-1148
    • Foy, E.1    Li, K.2    Wang, C.3    Sumpter, R.4    Ikeda, M.5    Lemon, S.M.6    Gale, M.7
  • 47
    • 23344440213 scopus 로고    scopus 로고
    • VX-950 (Vertex/Mitsubishi)
    • Summa V. VX-950 (Vertex/Mitsubishi). Curr Opin Investig Drugs 2005; 8: 831-837
    • (2005) Curr Opin Investig Drugs , vol.8 , pp. 831-837
    • Summa, V.1
  • 52
    • 33744477373 scopus 로고    scopus 로고
    • Nucleoside analog inhibitors of hepatitis C virus replicationInfect
    • Carroll SS, Olsen DB: Nucleoside analog inhibitors of hepatitis C virus replicationInfect. Disord Drug Targets 2006; 6: 17-29
    • (2006) Disord Drug Targets , vol.6 , pp. 17-29
    • Carroll, S.S.1    Olsen, D.B.2
  • 54
    • 34249065785 scopus 로고    scopus 로고
    • Early Viral Response to CpG 10101, a new investigational antiviral TLR9 agonist, in combination with pegylated interferon and/or ribavirin, in prior relapse HCV responders: Preliminary report of a randomized phase 1 study
    • McHutchison J, Ghalib R, Lawitz E, Freilich B, Kwo P, Masciari F, Himes JL, Al-Adhami M, Bacon B: Early Viral Response to CpG 10101, a new investigational antiviral TLR9 agonist, in combination with pegylated interferon and/or ribavirin, in prior relapse HCV responders: preliminary report of a randomized phase 1 study. Gastroenterology 2006; 130: S1062
    • (2006) Gastroenterology , vol.130
    • McHutchison, J.1    Ghalib, R.2    Lawitz, E.3    Freilich, B.4    Kwo, P.5    Masciari, F.6    Himes, J.L.7    Al-Adhami, M.8    Bacon, B.9
  • 56
    • 0028876839 scopus 로고
    • A family of transcriptional adaptor proteins targeted by the E1A oncoprotein
    • Arany Z, Newsome D, Oldread E, Livingston DM, Eckner R: A family of transcriptional adaptor proteins targeted by the E1A oncoprotein. Nature 1995; 374: 81-84
    • (1995) Nature , vol.374 , pp. 81-84
    • Arany, Z.1    Newsome, D.2    Oldread, E.3    Livingston, D.M.4    Eckner, R.5
  • 57
    • 0033912223 scopus 로고    scopus 로고
    • Adenovirus E1B 55-Kilodalton Oncoprotein Inhibits p53 Acetylation by PCAF
    • Liu Y, April L. Colosimo AL, Yang XJ, Liao D: Adenovirus E1B 55-Kilodalton Oncoprotein Inhibits p53 Acetylation by PCAF. Mol Cell Biol 2000; 20: 5540-5553
    • (2000) Mol Cell Biol , vol.20 , pp. 5540-5553
    • Liu, Y.1    April, L.2    Colosimo, A.L.3    Yang, X.J.4    Liao, D.5
  • 58
  • 59
    • 0034673702 scopus 로고    scopus 로고
    • HTLV-1 tax oncoprotein represses the p53-mediated trans-activation function through coactivator CBP sequestration
    • Ariumi Y, Kaida A, Lin JY, Hirota M, Masui O, Yamaoka S, Taya Y, Shimotohno K: HTLV-1 tax oncoprotein represses the p53-mediated trans-activation function through coactivator CBP sequestration. Oncogene 2000; 19: 1491-1499
    • (2000) Oncogene , vol.19 , pp. 1491-1499
    • Ariumi, Y.1    Kaida, A.2    Lin, J.Y.3    Hirota, M.4    Masui, O.5    Yamaoka, S.6    Taya, Y.7    Shimotohno, K.8
  • 60
    • 0033568491 scopus 로고    scopus 로고
    • The E6 protein of human papillomavirus type 16 binds to and inhibits co-activation by CBP and p300
    • Patel D, Huang SM, Baglia LA, McCance DJ: The E6 protein of human papillomavirus type 16 binds to and inhibits co-activation by CBP and p300. EMBO J 1999; 18: 5061-5072
    • (1999) EMBO J , vol.18 , pp. 5061-5072
    • Patel, D.1    Huang, S.M.2    Baglia, L.A.3    McCance, D.J.4
  • 61
    • 0034629279 scopus 로고    scopus 로고
    • Inactivation of interferon regulatory factor-1 tumor suppressor protein by HPV E7 oncoprotein. Implication for the E7-mediated immune evasion mechanism in cervical carcinogenesis
    • Park JS, Kim EJ, Kwon HJ, Hwang ES, Namkoong SE, Um SJ: Inactivation of interferon regulatory factor-1 tumor suppressor protein by HPV E7 oncoprotein. Implication for the E7-mediated immune evasion mechanism in cervical carcinogenesis. J Biol Chem 2000; 275: 6764-6769
    • (2000) J Biol Chem , vol.275 , pp. 6764-6769
    • Park, J.S.1    Kim, E.J.2    Kwon, H.J.3    Hwang, E.S.4    Namkoong, S.E.5    Um, S.J.6
  • 62
    • 0142123224 scopus 로고    scopus 로고
    • Modulation of retinoid signaling by a cytoplasmic viral protein via sequestration of Sp110b, a potent transcriptional corepressor of retinoic acid receptor, from the nucleus
    • Watashi K, Hijikata M, Tagawa A, Doi T, Marusawa H, Shimotohno K: Modulation of retinoid signaling by a cytoplasmic viral protein via sequestration of Sp110b, a potent transcriptional corepressor of retinoic acid receptor, from the nucleus. Mol Cell Biol 2003; 23: 7498-7509
    • (2003) Mol Cell Biol , vol.23 , pp. 7498-7509
    • Watashi, K.1    Hijikata, M.2    Tagawa, A.3    Doi, T.4    Marusawa, H.5    Shimotohno, K.6
  • 64
    • 0025905183 scopus 로고
    • The E2F transcription factor is a cellular target for the RB protein
    • Chellappan SP, Hiebert S, Mudryj M, Horowitz JM, Nevins, JR: The E2F transcription factor is a cellular target for the RB protein. Cell 1991; 65: 1053-1061
    • (1991) Cell , vol.65 , pp. 1053-1061
    • Chellappan, S.P.1    Hiebert, S.2    Mudryj, M.3    Horowitz, J.M.4    Nevins, J.R.5
  • 65
    • 0037313618 scopus 로고    scopus 로고
    • Coordinated regulation of life and death by RB
    • Chau BN, Wang JY: Coordinated regulation of life and death by RB. Nat Rev Cancer 2003; 3: 130-138
    • (2003) Nat Rev Cancer , vol.3 , pp. 130-138
    • Chau, B.N.1    Wang, J.Y.2
  • 66
    • 29144483321 scopus 로고    scopus 로고
    • Downregulation of the retinoblastoma tumor suppressor by the hepatitis C virus NS5B RNA-dependent RNA polymerase
    • Munakata T, Nakamura M, Liang Y, Li K, Lemon SM: Downregulation of the retinoblastoma tumor suppressor by the hepatitis C virus NS5B RNA-dependent RNA polymerase. Proc Natl Acad Sci USA 2005; 102: 18159-18164
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 18159-18164
    • Munakata, T.1    Nakamura, M.2    Liang, Y.3    Li, K.4    Lemon, S.M.5
  • 67
    • 0023914010 scopus 로고
    • Association between an oncogene and an anti-oncogene: The adenovirus E1A proteins bind to the retinoblastoma gene product
    • Whyte P, Buchkovich KJ, Horowitz JM, Friend SH, Raybuck M, Weinberg RA, Harlow E: Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product. Nature 1988; 334: 124-129
    • (1988) Nature , vol.334 , pp. 124-129
    • Whyte, P.1    Buchkovich, K.J.2    Horowitz, J.M.3    Friend, S.H.4    Raybuck, M.5    Weinberg, R.A.6    Harlow, E.7
  • 68
    • 0024535228 scopus 로고
    • The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product
    • Dyson N, Howley PM, Munger K, Harlow E: The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product. Science 1989; 243: 934-937
    • (1989) Science , vol.243 , pp. 934-937
    • Dyson, N.1    Howley, P.M.2    Munger, K.3    Harlow, E.4
  • 69
    • 2642601106 scopus 로고    scopus 로고
    • Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7
    • Lee JO, Russo AA, Pavletich NP: Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7. Nature 1998; 391: 859-865
    • (1998) Nature , vol.391 , pp. 859-865
    • Lee, J.O.1    Russo, A.A.2    Pavletich, N.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.