Effective clearance of intracellular Leishmania major in vivo requires pten in macrophages

European Journal of Immunology

Volumn 38, Issue 5, 2008, Pages 1331-1340

  Kuroda, Shoko ^a   Nishio, Miki ^a,b   Sasaki, Takehiko ^a   Horie, Yasuo ^a   Kawahara, Koichi ^a,b   Sasaki, Masato ^a   Natsui, Miyuki ^a   Matozaki, Takashi ^c   Tezuka, Hiroyuki ^a   Ohteki, Toshiaki ^a   Förster, Irmgard ^d   Wak, Tak W ^e   Nakano, Toru ^f   Suzuki, Akira ^a,b  

^a AKITA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c GUNMA UNIVERSITY   (Japan)

^d HEINRICH HEINE UNIVERSITY   (Germany)

^e UNIVERSITY OF TORONTO   (Canada)

^f OSAKA UNIVERSITY   (Japan)

Author keywords

Leishmania; Macrophage; Pten

Indexed keywords

ARGINASE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; LIGAND; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PHOSPHATASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; TENSIN; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; CRE RECOMBINASE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTEGRASE; INTERLEUKIN DERIVATIVE; LYSOZYME; LYSOZYME M, MOUSE; NITRITE; NOS2 PROTEIN, MOUSE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PHOSPHATIDYLINOSITOL 3,4,5-TRIPHOSPHATE; POLYPHOSPHOINOSITIDE; PTEN PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL MUTANT; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVITY; IN VITRO STUDY; IN VIVO STUDY; INFECTION SENSITIVITY; LEISHMANIA MAJOR; LEISHMANIASIS; LYMPH NODE; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SOUTHERN BLOTTING; TH1 CELL; WESTERN BLOTTING; WILD TYPE; ANIMAL; C57BL MOUSE; DISEASE PREDISPOSITION; DRUG EFFECT; DRUG POTENTIATION; ENZYMOLOGY; GENE DELETION; GENE EXPRESSION; GENETICS; IMMUNOLOGY; METABOLISM; PARASITOLOGY; PATHOLOGY; PERITONEUM MACROPHAGE; PHYSIOLOGY; SKIN LEISHMANIASIS; TRANSGENIC MOUSE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ARGINASE; DISEASE SUSCEPTIBILITY; GENE DELETION; GENE EXPRESSION; INTEGRASES; INTERFERON TYPE II; INTERLEUKINS; LEISHMANIA MAJOR; LEISHMANIASIS, CUTANEOUS; LYMPH NODES; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MURAMIDASE; NITRIC OXIDE SYNTHASE TYPE II; NITRITES; PHOSPHATIDYLINOSITOL PHOSPHATES; PTEN PHOSPHOHYDROLASE; TOLL-LIKE RECEPTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 47049086825     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200737302     Document Type: Article

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