Molecular mechanisms of lymphocyte homing to peripheral lymph nodes

Journal of Experimental Medicine

Volumn 187, Issue 2, 1998, Pages 205-216

  Warnock, R Aaron ^a,b   Askari, Sanaz ^c   Butcher, Eugene C ^a,b   Von Andrian, Ulrich H ^c,d  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VA PALO ALTO HEALTH CARE SYSTEM   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d CENTER FOR BLOOD RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

L SELECTIN; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; FEMALE; LYMPH NODE; LYMPHOCYTE ACTIVATION; LYMPHOCYTE HOMING; MALE; MONONUCLEAR CELL; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL;

ADOPTIVE TRANSFER; ANIMALS; CELL ADHESION; CELL MOVEMENT; ENDOTHELIUM, VASCULAR; FEMALE; GTP-BINDING PROTEINS; INTEGRINS; LEUKOCYTES; LYMPH NODES; LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; LYMPHOCYTES; MALE; MICE; MICE, INBRED BALB C; SIGNAL TRANSDUCTION; VENULES;

EID: 0031965102     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.187.2.205     Document Type: Article

References (61)

1. Gowans, J.L., and E.J. Knight. 1964. The route of re-circulation of lymphocytes in the rat. Proc. R. Soc. Lond. B. Biol. 159:257-282.
2. Butcher, E.C., R.G. Scollay, and I.L. Weissman. 1980. Organ specificity of lymphocyte migration: mediation by highly selective lymphocyte interaction with organ-specific determinants on high endothelial venules. Eur. J. Immunol. 10:556-561.
3. Butcher, E.C., and L.J. Picker. 1996. Lymphocyte homing and homeostasis. Science. 272:60-66.
4. Butcher, E.C. 1991. Leukocyte-endothelial cell recognition: three (or more) steps to specificity and diversity. Cell. 67: 1033-1036.
5. Shimizu, Y. W. Newman, Y. Tanaka, and S. Shaw. 1992. Lymphocyte interactions with endothelial cells. Immunol. Today. 13:106-112.
6. Springer, T.A. 1994. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multi-step paradigm. Cell. 76:301-314.
7. 2 integrins in vivo. Proc. Natl. Acad. Sci. USA. 88:7538-7542.
8. Lawrence, M.B., and T.A. Springer. 1991. Leukocytes roll on a selectin at physiologic flow rates: distinction from and prerequisite for adhesion through integrins. Cell. 65:859-873.
9. Bargatze, R.F., and E.C. Butcher. 1993. Rapid G protein-regulated activation event involved in lymphocyte binding to high endothelial venules. J. Exp. Med. 178:367-372.
10. Lawrence, M.B., E.L. Berg, E.C. Butcher, and T.A. Springer. 1995. Rolling of lymphocytes and neutrophils on peripheral node addressin and subsequent arrest on ICAM-1 in shear flow. Eur. J. Immunol. 25:1025-1031.
11. Bargatze, R.F., M.A. Jutila, and E.C. Butcher. 1995. Distinct roles of L-selectin and integrins α4β7 and LFA-1 in lymphocyte homing to Peyer's patch-HEV in situ: the multistep model confirmed and refined. Immunity. 3:99-108.
12. Arbonès, M.L., D.C. Ord, K. Ley, H. Ratech, C. Maynard-Curry, G. Otten, D.J. Capon, and T.F. Tedder. 1994. Lymphocyte homing and leukocyte rolling and migration are impaired in L-selectin-deficient mice. Immunity. 1:247-260.
13. Wagner, N., J. Lohler, E.J. Kunkel, K. Ley, E. Leung, G. Krissansen, K. Rajewsky, and W. Müller. 1996. Critical role for β7 integrins in formation of the gut-associated lymphoid tissue. Nature. 382:366-370.
14. Gallatin, W.M., I.L. Weissman, and E.C. Butcher. 1983. A cell-surface molecule involved in organ-specific homing of lymphocytes. Nature. 304:30-34.
15. Streeter, P.R., B.T.N. Rouse, and E.C. Butcher. 1988. Immunohistologic and functional characterization of a vascular addressin involved in lymphocyte homing into peripheral lymph nodes. J. Cell Biol. 107:1853-1862.
16. Tedder, T.F., D.A. Steeber, and P. Pizcueta. 1995. L-selectin-deficient mice have impaired leukocyte recruitment into inflammatory sites. J. Exp. Med. 181:2259-2264.
17. Catalina, M.D., M.C. Carroll, H. Arizpe, A. Takashima, P. Estess, and M.H. Siegelman. 1996. The route of antigen entry determines the requirement for L-selectin during immune responses. J. Exp. Med. 184:2341-2351.
18. Xu, J., I.S. Grewal, G.P. Geba, and R.A. Flavell. 1996. Impaired primary T cell responses in L-selectin-deficient mice. J. Exp. Med. 183:589-598.
19. Hamann, A., D.J. Westrich, A. Duijevstijn, E.C. Butcher, H. Baisch, R. Harder, and H.G. Thiele. 1988. Evidence for an accessory role of LFA-1 in lymphocyte-high endothelium interaction during homing. J. Immunol. 140:693-699.
20. Schmits, R., T.M. Kundig, D.M. Baker, G. Shumaker, J.J. Simard, G. Duncan, A. Wakeham, A. Shahiman, A. van der Heiden, M.F. Bachmann, et al. 1996. LFA-1-deficient mice show normal CTL responses to virus but fail to reject immunogenic tumor. J. Exp. Med. 183:1415-1426.
21. Spangrude, G.J., B.A. Braaten, and R.A. Daynes. 1984. Molecular mechanisms of lymphocyte extravasation. I. Studies of two selective inhibitors of lymphocyte recirculation. J. Immunol. 132:354-362.
22. Chaffin, K.E., C.R. Beals, T.M. Wilkie, K.A. Forbush, M.I. Simon, and R.M. Perlmutter. 1990. Dissection of thymocyte signaling pathways by in vivo expression of pertussis toxin ADP-ribosyltransferase. EMBO (Eur. Mol. Biol. Organ.) J. 9: 3821-3829.
23. Pizza, M., A. Covacci, A. Bartoloni, M. Perugini, L. Nencioni, M.T. De Magistris, L. Villa, D. Nucci, R. Manetti, and M. Bugnoli. 1989. Mutants of pertussis toxin suitable for vaccine development. Science. 246:497-500.
24. Sanchez-Madrid, F., P. Simon, S. Thompson, and T.A. Springer. 1983. Mapping of antigenic and functional epitopes on the α and β subunits of two related glycoproteins involved in cell interactions, LFA-1 and Mac-1. J. Exp. Med. 158:586-602.
25. von Andrian, U.H. 1996. Intravital microscopy of the peripheral lymph node microcirculation in mice. Microcirculation. 3:287-300.
26. Pries, A.R. 1988. A versatile video image analysis system for microcirculatory research. Int. J. Microcirc. Clin. Exp. 7:327-345.
27. Stewart, M., and N. Hogg. 1996. Regulation of leukocyte integrin function: Affinity vs. avidity. J. Cell. Biochem. 61: 554-561.
28. 2-integrin-mediated neutrophil adhesion at physiological shear rates in vivo. Am. J. Physiol. 263:H1034-H1044.
29. 4-integrin, P-selectin, and E-selectin in an allergic model of inflammation. J. Exp. Med. 185:1077-1087.
30. De Bruyn, P.P., and Y. Cho. 1990. Structure and function of high endothelial postcapillary venules in lymphocyte circulation. Nature. 84:85-101.
31. Marchesi, V.T., and J.L. Gowans. 1963. The migration of lymphocytes through the endothelium of venules in lymph nodes: an electron microscope study. Proc. R. Soc. Lond. B. Biol. 159:283-290.
32. Kikuta, A., and S.D. Rosen. 1994. Localization of ligands for L-selectin in mouse peripheral lymph node high endothelial cells by colloidal gold conjugates. Blood. 84:3766-3775.
33. Sasaki, K., Y. Okouchi, H.-J. Rothkötter, and K. Pabst. 1996. Ultrastructural localization of the intercellular adhesion molecule (ICAM-1) on the cell surface of high endothelial venules in lymph nodes. Anat. Rec. 244:105-111.
34. Laudanna, C., G. Constantin, P. Baron, E. Scarpini, G. Scarlato, G. Cabrini, C. Dechecchi, F. Rossi, M.A. Cassatella, and G. Berton. 1994. Sulfatides trigger increase of cytosolic free calcium and enhanced expression of tumor necrosis factor-α and interleukin-8 mRNA in human neutrophils. J. Biol. Chem. 269:4021-4026.
35. Brenner, B., E. Gulbins, K. Schlottmann, U. Koppenhoefer, G.L. Busch, B. Walzog, M. Steinhausen, K.M. Coggeshall, O. Linderkamp, and F. Lang. 1997. L-selectin activates the Ras pathway via the tyrosine kinase p56lck. Proc. Natl. Acad. Sci. USA. 93:15376-15381.
36. Sikorski, M.A., D.E. Staunton, and J.W. Mier. 1996. L-selectin crosslinking induces integrin-dependent adhesion: evidence for a signaling pathway involving PTK but not PKC. Cell Adhes. Commun. 4:355-367.
37. Hwang, S.T., M.S. Singer, P.A. Giblin, T.A. Yednock, K.B. Bacon, S.I. Simon, and S.D. Rosen. 1996. GlyCAM-1, a physiologic ligand for L-selectin, activates β 2 integrins on naive peripheral lymphocytes. J. Exp. Med. 184:1343-1348.
38. Picker, L.J., and E.C. Butcher. 1992. Physiological and molecular mechanisms of lymphocyte homing. Annu. Rev. Immunol. 10:561-591.
39. Williams, M.B., and E.C. Butcher. 1997. Homing of naïve and memory T lymphocyte subsets to Peyer's patches, lymph nodes, and spleen. J. Immunol. 159:1746-1752.
40. Mackay, C. 1993. Homing of naive, memory and effector lymphocytes. Curr. Opin. Immunol. 5:423-427.
41. Diacovo, T.G., K.D. Puri, R.A. Warnock, T.A. Springer, and U.H. von Andrian. 1996. Platelet-mediated lymphocyte delivery to high endothelial venules. Science. 273:252-255.
42. Diacovo, T.G., M.D. Catalina, M.H. Siegelman, and U.H. von Andrian. 1998. Circulating activated platelets reconstitute lymphocyte homing and peripheral immunity in L-selectin-deficient mice J. Exp. Med. 187:197-204.
43. Shier, P., G. Otulakowski, K. Ngo, J. Panakos, E. Chourmouzis, L. Christjansen, C.Y. Lau, and W.P. Fung-Leung. 1996. Impaired immune responses toward alloantigens and tumor cells but normal thymic selection in mice deficient in the β2 integrin leukocyte function-associated antigen-1. J. Immunol. 157:5375-5386.
44. Dustin, M.L., and T.A. Springer. 1989. T cell receptor cross-linking transiently stimulates adhesiveness through LFA-1. Nature. 341:619-624.
45. van Kooyk, Y., P. van de Wiel-van Kemenade, P. Weder, T.W. Kuijpers, and C.G. Figdor. 1989. Enhancement of LFA-1-mediated cell adhesion by triggering through CD2 or CD3 on T lymphocytes. Nature. 342:811-813.
46. Laudanna, C., J.J. Campbell, and E.C. Butcher. 1996. Role of Rho in chemoattractant-activated leukocyte adhesion through integrins. Science. 271:981-983.
47. Campbell, J.J., J. Hedrick, A. Zlotnik, M.A. Siani, D.A. Thompson, and E.C. Butcher. 1998. Novel chemokines trigger rapid arrest of rolling lymphocytes under physiologic shear. Science. In press.
48. Nickoloff, B.J., and R.S. Mitra. 1988. Phorbol ester treatment enhances binding of the mononuclear leukocytes to autologous and allogenic gamma-interferon-treated keratinocytes, which are blocked by anti-LFA-1 monoclonal antibody. J. Investig. Dermatol. 90:684-689.
49. Andrew, D.P., C. Berlin, S. Honda, T. Yoshino, A. Hamann, B. Holzmann, P.J. Kilshaw, and E.C. Butcher. 1994. Distinct but overlapping epitopes are involved in α4β7-mediated adhesion to vascular cell adhesion molecule-1, mucosal addressin-1, fibronectin, and lymphocyte aggregation. J. Immunol. 153:3847-3861.
50. Jung, T.M., W.M. Gallatin, I.L. Weissman, and M.O. Dailey. 1988. Down-regulation of homing receptors after T cell activation. J. Immunol. 141:4110-4117.
51. Lewinsohn, D.M., K.F. Bargatze, and E.C. Butcher. 1987. Leukocyte-endothelial cell recognition: evidence of a common molecular mechanism shared by neutrophils, lymphocytes, and other leukocytes. J. Immunol. 138:4313-4321.
52. May, M.J., G. Entwistle, M.J. Humphries, and A. Ager. 1993. VCAM-1 is a CS1 peptide-inhibitable adhesion molecule expressed by lymph node high endothelium. J. Cell. Sci. 106:109-119.
53. Szabo, M.C., E.C. Butcher, and L.M. McEvoy. 1997. Specialization of mucosal follicular dendritic cells revealed by mucosal addressin-cell adhesion molecule-1 display. J. Immunol. 158:5584-5588.
54. Hahne, M., M. Lenter, U. Jäger, S. Isenmann, and D. Vestweber. 1993. VCAM-1 is not involved in LPAM-1 (α4βp/ α4β7) mediated binding of lymphoma cells to high endothelial venules of mucosa-associated lymph nodes. Eur. J. Cell. Biol. 61:290-298.
55. Nakache, M., E.L. Berg, P.R. Streeter, and E.C. Butcher. 1989. The mucosal vascular addressin is a tissue-specific endothelial cell adhesion molecule for circulating lymphocytes. Nature. 337:179-181.
56. Hamann, A., D.P. Andrew, D. Jablonski-Westrich, B. Holzmann, and E.C. Butcher. 1994. Role of α4-integrins in lymphocyte homing to mucosal tissues in vivo. J. Immunol. 152: 3282-3293.
57. Hamann, A., D. Jablonski-Westrich, V. Jonas, and H.-G. Thiele. 1991. Homing receptors reexamined: mouse LECAM-1 (MEL-14 antigen) is involved in lymphocyte migration into gut-associated lymphoid tissue. Eur. J. Immunol. 21:2925-2929.
58. Miura, S., Y. Tsuzuki, I. Kurose, M. Suematsu, T. Shigematsu, H. Kimura, H. Higuchi, H. Serizawa, H. Yagita, K. Okumura, et al. 1996. Endotoxin stimulates lymphocyte-endothelial interactions in rat intestinal Peyer's patches and villus mucosa. Am. J. Physiol. 271:G282-G292.
59. Jalkanen, S., R.F. Bargatze, J. de los Toyos, and E.C. Butcher. 1987. Lymphocyte recognition of high endothelium: antibodies to distinct epitopes of an 85-95 kD glycoprotein antigen differentially inhibit lymphocyte binding to lymph node, mucosal and synovial endothelial cells. J. Cell Biol. 105:983-993.
60. McEvoy, L.M., H. Sun, J.G. Frelinger, and E.C. Butcher. 1997. Anti-CD43 Inhibition of T Cell Homing. J. Exp. Med. 185:1493-1498.
61. Salmi, M., and S. Jalkanen. 1996. Human vascular adhesion protein 1 (VAP-1) is a unique sialoglycoprotein that mediates carbohydrate-dependent binding of lymphocytes to endothelial cells. J. Exp. Med. 183:569-579.