Diastereoselective dihydroxylation and regioselective deoxygenation of dihydropyranones: A novel protocol for the stereoselective synthesis of C 1-C8 and C15-C21 subunits of (+)-discodermolide

Journal of Organic Chemistry

Volumn 69, Issue 19, 2004, Pages 6294-6304

  Ramachandran, P Veeraraghavan ^a   Prabhudas, Bodhuri ^a   Chandra, J Subash ^a   Reddy, M Venkat Ram ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON; HYDROXYLATION; ISOTOPES; OXIDATION; STEREOCHEMISTRY; SYNTHESIS (CHEMICAL);

DIASTEREOSELECTIVE DIHYDROXYLATION; DIHYDROPYRANONES; LACTONES; REGIOSELECTIVITY;

KETONES;

1,3 BETA HYDROXY DELTA LACTONE DERIVATIVE; ALPHA PYRANONE DERIVATIVE; BORANE DERIVATIVE; DIHYDROPYRANONE DERIVATIVE; DISCODERMOLIDE; LACTONE DERIVATIVE; PACLITAXEL; PINENE; PYRAN DERIVATIVE; REAGENT; UNCLASSIFIED DRUG;

ACETALIZATION; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL REACTION; CHIRALITY; CONTROLLED STUDY; DEOXYGENATION; DEPROTECTION REACTION; DIASTEREOISOMER; DIHYDROXYLATION; DRUG CYTOTOXICITY; DRUG HYDROLYSIS; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; IODINATION; MICROTUBULE; OPTICAL ROTATION; PHARMACOPHORE; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; RING CLOSING METATHESIS; STEREOCHEMISTRY; TECHNIQUE; TRANS ISOMER;

EID: 4644220374     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo0492416     Document Type: Article

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