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Volumn 624, Issue 1-2, 2001, Pages 239-243

Asymmetric allylboration for the synthesis of β-hydroxy-δ-lactone unit of statin drug analogs

Author keywords

Allylboration; Asymmetric synthesis; Epoxidation; Metathesis; Reduction

Indexed keywords


EID: 0001514115     PISSN: 0022328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-328X(01)00665-9     Document Type: Article
Times cited : (42)

References (72)
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    • (c) http://www.pharminfo.com/ pubs/msb/statins.html.
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    • Mevacor® is a trademark of Merck & Co
    • Mevacor® is a trademark of Merck & Co.
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    • Launched in the market (Merck & Co.) in 1988. FDA approved new dose ranges for Zocor® in 1998
    • Launched in the market (Merck & Co.) in 1988. FDA approved new dose ranges for Zocor® in 1998.
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    • Pravachol is a trademark of Bristol-Myers Squibb. FDA approved in 1996
    • Pravachol is a trademark of Bristol-Myers Squibb. FDA approved in 1996.
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    • FDA approved in 1996, Lipitor® is a trademark of Pfizer (Parke-Davis)
    • FDA approved in 1996, Lipitor® is a trademark of Pfizer (Parke-Davis).
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    • 0346541137 scopus 로고    scopus 로고
    • Launched in the market in 1995. Baycol® is a trademark of Bayer in the USA
    • Launched in the market in 1995. Baycol® is a trademark of Bayer in the USA.
  • 11
    • 0345910028 scopus 로고    scopus 로고
    • Lescol is a trademark of Novartis Pharma AG
    • Lescol is a trademark of Novartis Pharma AG.
  • 12
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    • Statin drugs constituted ∼ 6% of the total annual sale of the top 200 drugs in 1999, worth $125 billion in the USA. Lipitor, $3.0b; Zocor, $2.3b; Pravacol, $1.18b; Mevacor, $389.5m; and Lescol, $268.1m. For a listing of the top 200 prescription drugs, see: http://www.rxlist.com and a listing of the top 200 drugs in sales, see: http://www.pharmacyline.com.
  • 13
    • 0347171431 scopus 로고    scopus 로고
    • Statin drugs constituted ∼ 6% of the total annual sale of the top 200 drugs in 1999, worth $125 billion in the USA. Lipitor, $3.0b; Zocor, $2.3b; Pravacol, $1.18b; Mevacor, $389.5m; and Lescol, $268.1m. For a listing of the top 200 prescription drugs, see: http://www.rxlist.com and a listing of the top 200 drugs in sales, see: http://www.pharmacyline.com.
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    • 1H-NMR spectroscopy
    • 1H-NMR spectroscopy.
  • 59
    • 0345910019 scopus 로고    scopus 로고
    • Chiralcel® OD-H™ is a product of Chiral Technologies, Inc. Exton, PA
    • Chiralcel® OD-H™ is a product of Chiral Technologies, Inc. Exton, PA.
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    • 0032924763 scopus 로고    scopus 로고
    • and references cited therein
    • (b) Wright, D.L. Current Org. Chem. 3 (1999) 211 and references cited therein.
    • (1999) Current Org. Chem. , vol.3 , pp. 211
    • Wright, D.L.1
  • 72
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    • Wiley-Interscience, New York, 1975 Reprinted edition, Aldrich Chemical Co. Inc., Milwaukee, WI, Chapter 9
    • H.C. Brown, G.W. Kramer, A.B. Levy, M.M. Midland, Organic Syntheses via Boranes, Wiley-Interscience, New York, 1975 Reprinted edition, vol. 1. Aldrich Chemical Co. Inc., Milwaukee, WI, 1997, Chapter 9.
    • (1997) Organic Syntheses Via Boranes , vol.1
    • Brown, H.C.1    Kramer, G.W.2    Levy, A.B.3    Midland, M.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.