A short synthesis of the C15-C21 segment of (+)-discodermolide, based on an asymmetric approach from achiral 2-methyl-1,3-propanediol to versatile enantiopure stereotriads

Tetrahedron Letters

Volumn 43, Issue 36, 2002, Pages 6373-6376

  Shahid, Kazi A ^a   Li, Yong Nan ^b   Okazaki, Momotoshi ^a   Shuto, Yoshihiro ^a   Goto, Fumitaka ^c   Kiyooka, Syun Ichi ^b  

^a EHIME UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c OTSUKA PHARMACEUTICAL CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2 METHYL 1,3 PROPANEDIOL DIOCTANOATE; ALDEHYDE; BROMINE DERIVATIVE; DISCODERMOLIDE; OXAZABOROLIDINE DERIVATIVE; PROPANEDIOL DERIVATIVE; SILICON DERIVATIVE; UNCLASSIFIED DRUG;

ALDOL REACTION; ARTICLE; ASYMMETRIC SYNTHESIS; CHIRALITY; DRUG SYNTHESIS; ENANTIOMER; RACEMIC MIXTURE;

EID: 0037009708     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(02)01373-4     Document Type: Article

References (28)

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28. 3, 100 MHz) δ (ppm) -5.4, -5.3, -4.1, -3.9, 10.4, 14.2, 14.4, 15.3, 18.3, 18.4, 26.0, 26.1, 38.6, 38.8, 44.8, 55.3, 60.2, 64.4, 74.4, 75.4, 81.8, 113.7, 129.0, 131.5, 159.1, 174.4.