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Volumn 4, Issue 14, 2002, Pages 2397-2400

Studies directed toward the total synthesis of discodermolide: Asymmetric synthesis of the C1-C14 fragment

Author keywords

[No Author keywords available]

Indexed keywords

ALKANE; ANTINEOPLASTIC AGENT; CARBAMIC ACID DERIVATIVE; DISCODERMOLIDE; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; LACTONE; PYRONE DERIVATIVE;

EID: 0037062876     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol026139r     Document Type: Article
Times cited : (53)

References (58)
  • 2
    • 85022401932 scopus 로고
    • Gunasekera, S. P.; Gunasekera, M.; Longley, R. E.; Schulte, G. K. J. Org. Chem. 1990, 55, 4912-4915. Additions and corrections: J. Org. Chem. 1991, 56, 1346.
    • (1991) J. Org. Chem. , vol.56 , pp. 1346
  • 32
    • 0041494737 scopus 로고    scopus 로고
    • Ph.D. Thesis, Harvard University, Cambridge, MA
    • (g) Halstead, D. P. Ph.D. Thesis, Harvard University, Cambridge, MA, 1998.
    • (1998)
    • Halstead, D.P.1
  • 43
    • 0041494736 scopus 로고    scopus 로고
    • note
    • Other debenzylation conditions, such as hydrogenation, transfer hydrogenation, or metal in liquid ammonia reduction either gave back starting material or caused decomposition of the substrate.
  • 47
    • 0042496546 scopus 로고    scopus 로고
    • note
    • 2 as a solvent allowed us to upscale the aldol reaction and run it with reproducibly good yields on a 20-500 mg scale.
  • 48
    • 0041995728 scopus 로고    scopus 로고
    • note
    • The relative stereochemistry was assigned by NOE analysis of the acetal, derived from 22: (Matrix Presented)


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.