Zfp64 participates in Notch signaling and regulates differentiation in mesenchymal cells

Journal of Cell Science

Volumn 121, Issue 10, 2008, Pages 1613-1623

  Sakamoto, Kei ^a   Tamamura, Yoshihiro ^a   Katsube, Ken Ichi ^a   Yamaguchi, Akira ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Notch; Runx2; Zinc finger protein 64

Indexed keywords

NOTCH1 RECEPTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR HES 1; TRANSCRIPTION FACTOR HEY 1; TRANSCRIPTION FACTOR RUNX2; ZINC FINGER PROTEIN; ZINC FINGER PROTEIN 64;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; MESENCHYME CELL; MOUSE; MUSCLE DEVELOPMENT; NONHUMAN; NUCLEOTIDE SEQUENCE; OSTEOBLAST; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TRANSACTIVATION; UPREGULATION;

ANIMALS; BASE SEQUENCE; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL CYCLE PROTEINS; CELL DIFFERENTIATION; CELL LINE; CORE BINDING FACTOR ALPHA 1 SUBUNIT; DNA-BINDING PROTEINS; HOMEODOMAIN PROTEINS; HUMANS; MESENCHYMAL STEM CELLS; MESODERM; MICE; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; RECEPTOR, NOTCH1; SIGNAL TRANSDUCTION; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; UP-REGULATION;

EID: 46249088059     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.023119     Document Type: Article

References (42)

1. Dahlqvist, C., Blokzijl, A., Chapman, G., Falk, A., Dannaeus, K., Ibanez, C. F. and Lendahl, U. (2003). Functional Notch signaling is required for BMP4-induced inhibition of myogenic differentiation. Development 130, 6089-6099.
2. de Jong, D. S., Vaes, B. L., Dechering, K. J., Feijen, A., Hendriks, J. M., Wehrens, R., Mummery, C. L., van Zoelen, E. J., Olijve, W. and Steegenga, W. T. (2004). Identification of novel regulators associated with early-phase osteoblast differentiation. J. Bone Miner Res. 19, 947-958.
3. Deregowski, V., Gazzerro, E., Priest, L., Rydziel, S. and Canalis, E. (2006). Notch 1 overexpression inhibits osteoblastogenesis by suppressing Wnt/beta-catenin but not bone morphogenetic protein signaling. J Biol. Chem. 281, 6203-6210.
4. Ducy, P. (2000). Cbfa1: a molecular switch in osteoblast biology. Dev. Dyn. 219, 461-471.
5. Ehebauer, M., Hayward, P. and Martinez-Arias, A. (2006). Notch signaling pathway. Sci. STKE 2006, cm7.
6. Fryer, C. J., White, J. B. and Jones, K. A. (2004). Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover. Mol. Cell 16, 509-520.
7. Gaikwad, J. S., Cavender, A. and D'Souza, R. N. (2001). Identification of tooth-specific downstream targets of Runx2. Gene 279, 91-97.
8. Gersbach, C. A., Byers, B. A., Pavlath, G. K. and Garcia, A. J. (2004). Runx2/Cbfa1 stimulates transdifferentiation of primary skeletal myoblasts into a mineralizing osteoblastic phenotype. Exp. Cell Res. 300, 406-417.
9. Gupta-Rossi, N., Le Bail, O., Gonen, H., Brou, C., Logeat, F., Six, E., Ciechanover, A. and Israel, A. (2001). Functional interaction between SEL-10, an F-box protein, and the nuclear form of activated Notch1 receptor. J. Biol. Chem. 276, 34371-34378.
10. Hirata, K., Tsukazaki, T., Kadowaki, A., Furukawa, K., Shibata, Y., Moriishi, T., Okubo, Y., Bessho, K., Komori, T., Mizuno, A. et al. (2003). Transplantation of skin fibroblasts expressing BMP-2 promotes bone repair more effectively than those expressing Runx2. Bone 32, 502-512.
11. Hubbard, E. J., Dong, Q. and Greenwald, I. (1996). Evidence for physical and functional association between EMB-5 and LIN-12 in Caenorhabditis elegans. Science 273, 112-115,
12. Itoh, F., Itoh, S., Goumans, M. J., Valdimarsdottir, G., Iso, T., Dotto, G. P, Hamamori, Y., Kedes, L., Kato, M. and ten Dijke, P. (2004). Synergy and antagonism between Notch and BMP receptor signaling pathways in endothelial cells. EMBO J 23, 541-551.
13. Katagiri, T., Yamaguchi, A., Komaki, M., Abe, E., Takahashi, N., Ikeda, T., Rosen, V., Wozney, J. M., Fujisawa-Sehara, A. and Suda, T. (1994). Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage. J. Cell Biol. 127, 1755-1766.
14. Komori, T. (2005). Regulation of skeletal development by the Runx family of transcription factors. J. Cell. Biochem. 95, 445-453.
15. Kopan, R., Nye, J. S. and Weintraub, H. (1994). The intracellular domain of mouse Notch: a constitutively activated repressor of myogenesis directed at the basic helix-loop-helix region of MyoD. Development 120, 2385-2396.
16. Lee, J. S., Thomas, D. M., Gutierrez, G., Carty, S. A., Yanagawa, S. and Hinds, P. W. (2006). HES1 cooperates with pRb to activate RUNX2-dependent transcription. J. Bone Miner Res. 21, 921-933.
17. Liu, T., Gao, Y., Sakamoto, K., Minamizato, T., Furukawa, K., Tsukazaki, T., Shibata, Y., Bessho, K., Komori, T. and Yantaguchi, A. (2007). BMP-2 promotes differentiation of osteoblasts and chondroblasts to Runx2-deficient cell lines. J. Cell. Physiol. 211, 728-735.
18. Mackay, J. P. and Crossley, M. (1998). Zinc fingers are sticking together. Trends Biochem. Sci. 23, 1-4.
19. Matsuno, K., Eastman, D., Mitsiades, T., Quinn, A. M., Carcanciu, M. L., Ordentlich, P., Kadesch, T. and Artavanis-Tsakonas, S. (1998). Human deltex is a conserved regulator of Notch signalling. Nat. Genet. 19, 74-78.
20. McLarren, K. W., Lo, R., Grbavec, D., Thirunavukkarasu, K., Karsenty, G. and Stifani, S. (2000). The mammalian basic helix loop helix protein HES-1 binds to and modulates the transactivating function of the runt-related factor Cbfal. J. Biol. Chem. 275, 530-538.
21. Minamizato, T., Sakamoto, K., Liu, T., Kokubo, H., Katsube, K. I., Perbal, B., Nakamura, S. and Yamaguchi, A. (2007). CCN3/NOV inhibits BMP-2-induced osteoblast differentiation by interacting with BMP arid Notch signaling pathways. Biochem. Biophys. Res. Commun. 354, 567-573.
22. Nam, Y., Weng, A. P., Aster, J. C. and Blacklow, S. C. (2003). Structural requirements for assembly of the CSL.intracellular Notch 1.Mastermind-like 1 transcriptional activation complex. J. Biol. Chem. 278, 21232-21239.
23. Nam, Y., Sliz, P., Pear, W. S., Aster, J. C. and Blacklow, S. C. (2007). Cooperative assembly of higher-order Notch complexes functions as a switch to induce transcription. Proc. Natl. Acad. Sci. USA 104, 2103-2108.
24. Nobta, M., Tsukazaki, T., Shibata, Y., Xin, C., Moriishi, T., Sakano, S., Shindo, H. and Yamaguchi, A. (2005). Critical regulation of bone morphogenetic protein-induced osteoblastic differentiation by Deltal/ Jaggedl-activated Notchl signaling. J. Biol. Chem. 280, 15842-15848.
25. Nofziger, D., Miyamoto, A., Lyons, K. M. and Weinmaster, G. (1999), Notch signaling imposes two distinct blocks in the differentiation of C2C12 myoblasts. Development 126, 1689-1702.
26. Oberg, C., Li, J., Pauley, A., Wolf, E., Gurney, M. and Lendahl, U. (2001). The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian Sel10 homolog. J. Biol. Chem. 276, 35847-35853.
27. Sakamoto, K., Nakamura, H., Takagi, M., Takeda, S. and Katsube, K. (1998). Ectopic expression of lunatic Fringe leads to downregulation of Serrate-1 in the developing chick neural tube; analysis using in ovo electroporation transfection technique. FEBS Lett. 426, 337-341.
28. Sakamoto, K., Yamaguchi, S., Ando, R., Miyawaki, A., Kabasawa, Y., Takagi, M., Li, C. L., Perbal, B. and Katsube, K. (2002). The nephroblastoma overexpressed gene (NOV/ccn3) protein associates with Notchl extracellular domain and inhibits myoblast differentiation via Notch signaling pathway. J. Biol. Chem. 277, 29399-29405.
29. Sakamoto, K., Chao, W. S., Katsube, K. and Yamaguchi, A. (2005). Distinct roles of EGF repeats for the Notch signaling system. Exp. Cell Res. 302, 281-291.
30. Sciaudone, M., Gazzerro, E., Priest, L., Delany, A. M. and Canalis, E. (2003). Notch 1 impairs osteoblastic cell differentiation. Endocrinology 144, 5631-5639.
31. Shawber, C., Nofziger, D., Hsieh, J. J., Lindsell, C., Bogler, O., Hayward, D. and Weinmaster, G. (1996). Notch signaling inhibits muscle cell differentiation through a CBF1-independent pathway. Development 122, 3765-3773.
32. Shindo, K., Kawashima, N., Sakamoto, K., Yamaguchi, A., Umezawa, A., Takagi, M., Katsube, K. and Suda, H. (2003). Osteogenic differentiation of the mesenchymal progenitor cells, Kusa is suppressed by Notch signaling. Exp. Cell Res. 290, 370-380.
33. Stelzl, U., Worm, U., Lalowski, M., Haenig, C., Brembeck, F. H., Goehler, H., Stroedicke, M., Zenkner, M., Schoenherr, A., Koeppen, S. et al. (2005). A human protein-protein interaction network: a resource for annotating the proteome. Cell 122, 957-968.
34. Sun, Y., Lowther, W., Kato, K., Bianco, C., Kenney, N., Strizzi, L., Raafat, D., Hirota, M., Khan, N. I. Bargo, S. et al. (2005). Notch4 intracellular domain binding to Smad3 and inhibition of the TGF-beta signaling. Oncogene 24, 5365-5374.
35. Takizawa, T., Ochiai, W., Nakashima, K. and Taga, T. (2003). Enhanced gene activation by Notch and BMP signaling cross-talk. Nucleic Acids Res. 31, 5723-5731.
36. Tezuka, K., Yasuda, M., Watanabe, N., Morimura, N., Kuroda, K., Miyatani, S. and Hozumi, N. (2002). Stimulation of osteoblastic cell differentiation by Notch. J. Bone Miner. Res. 17, 231-239.
37. Wang, W. and Malcolm, B. A. (1999). Two-stage PCR protocol allowing introduction of multiple mutations, deletions and insertions using QuikChange Site-Directed Mutagenesis. Biotechniques 26, 680-682.
38. Weng, A. P., Ferrando, A. A., Lee, W., Morris, J. P., 4th, Silverman, L. B., Sanchez-Irizarry, C., Blacklow, S. C., Look, A. T. and Aster, J. C. (2004). Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia. Science 306, 269-271.
39. Wilson, A. and Radtke, F. (2006). Multiple functions of Notch signaling in self-renewing organs and cancer. FEBS Lett. 580, 2860-2868.
40. Wu, G., Lyapina, S., Das, I., Li, J., Gurney, M., Pauley, A., Choi, L, Deshaies, R. J. and Kitajewski, J. (2001). SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation. Mol. Cell. Biol. 21, 7403-7415.
41. Zamurovic, N., Cappellen, D., Rohner, D. and Susa, M. (2004). Coordinated activation of notch, Wnt, and transforming growth factor-beta signaling pathways in bone morphogenic protein 2-induced osteogenesis. Notch target gene Hey1 inhibits mineralization and Runx2 transcriptional activity. J. Biol. Chem. 279, 37704-37715.
42. Zhou, S., Fujimuro, M., Hsieh, J. J., Chen, L., Miyamoto, A., Weinmaster, G. and Hayward, S. D. (2000). SKIP, a CBF1-associated protein, interacts with the ankyrin repeat domain of NotchIC To facilitate NotchIC function. Mol. Cell. Biol. 20, 2400-2410.