-
1
-
-
0035073210
-
In vitro and in vivo induction of bone formation using a recombinant adenoviral vector carrying the human BMP-2 gene
-
Cheng SL, Lou J, Wright NM, Lai CF, Avioli LV, Riew KD. In vitro and in vivo induction of bone formation using a recombinant adenoviral vector carrying the human BMP-2 gene. Calcif Tissue Int 2001; 68:87-94.
-
(2001)
Calcif Tissue Int
, vol.68
, pp. 87-94
-
-
Cheng, S.L.1
Lou, J.2
Wright, N.M.3
Lai, C.F.4
Avioli, L.V.5
Riew, K.D.6
-
2
-
-
0036046175
-
Ex vivo gene therapy with stromal cells transduced with a retroviral vector containing the BMP4 gene completely heals critical size calvarial defect in rats
-
Gysin R, Wergedal JE, Sheng MH, Kasukawa Y, Miyakoshi N, Chen ST, Peng H, Lau KH, Mohan S, Baylink DJ. Ex vivo gene therapy with stromal cells transduced with a retroviral vector containing the BMP4 gene completely heals critical size calvarial defect in rats. Gene Ther 2002;9:991-9.
-
(2002)
Gene Ther
, vol.9
, pp. 991-999
-
-
Gysin, R.1
Wergedal, J.E.2
Sheng, M.H.3
Kasukawa, Y.4
Miyakoshi, N.5
Chen, S.T.6
Peng, H.7
Lau, K.H.8
Mohan, S.9
Baylink, D.J.10
-
3
-
-
0033852160
-
Ex vivo gene therapy to produce bone using different cell types
-
Musgrave DS, Bosch P, Lee JY, Pelinkovic D, Ghivizzani SC, Whalen J, Niyibizi C, Huard J. Ex vivo gene therapy to produce bone using different cell types. Clin Orthop 2000;378:290-305.
-
(2000)
Clin Orthop
, vol.378
, pp. 290-305
-
-
Musgrave, D.S.1
Bosch, P.2
Lee, J.Y.3
Pelinkovic, D.4
Ghivizzani, S.C.5
Whalen, J.6
Niyibizi, C.7
Huard, J.8
-
4
-
-
0036295715
-
Adenoviral BMP-2 gene transfer in mesenchyinal stem cells: In vitro and in vivo bone formation on biodegradable polymer scaffolds
-
Partridge K, Yang X, Clarke NM, Okubo Y, Besshof K, Sebald W, Howdle SM, Shakesheff KM, Oreffo RO. Adenoviral BMP-2 gene transfer in mesenchyinal stem cells: in vitro and in vivo bone formation on biodegradable polymer scaffolds. Biochem Biophys Res Commun 2002;292:144-152.
-
(2002)
Biochem Biophys Res Commun
, vol.292
, pp. 144-152
-
-
Partridge, K.1
Yang, X.2
Clarke, N.M.3
Okubo, Y.4
Besshof, K.5
Sebald, W.6
Howdle, S.M.7
Shakesheff, K.M.8
Oreffo, R.O.9
-
5
-
-
0031685274
-
Induction of bone formation using a recombinant adenoviral vector carrying the human BMP-2 gene in a rabbit spinal fusion model
-
Riew KD, Wright NM, Cheng S, Avioli LV, Lou J. Induction of bone formation using a recombinant adenoviral vector carrying the human BMP-2 gene in a rabbit spinal fusion model. Calcif Tissue Int 1998; 63:357-60.
-
(1998)
Calcif Tissue Int
, vol.63
, pp. 357-360
-
-
Riew, K.D.1
Wright, N.M.2
Cheng, S.3
Avioli, L.V.4
Lou, J.5
-
6
-
-
0035345628
-
Engineered human mesenchyinal stem cells: A novel platform for skeletal cell mediated gene therapy
-
Turgeman G, Pittman DD, Muller R, Kurkalli BG, Zhou S, Pelled G, Peyser A, Zilberman Y, Moutsatsos IK, Gazit D. Engineered human mesenchyinal stem cells: a novel platform for skeletal cell mediated gene therapy. J Gene Med 2001;3:240-51.
-
(2001)
J Gene Med
, vol.3
, pp. 240-251
-
-
Turgeman, G.1
Pittman, D.D.2
Muller, R.3
Kurkalli, B.G.4
Zhou, S.5
Pelled, G.6
Peyser, A.7
Zilberman, Y.8
Moutsatsos, I.K.9
Gazit, D.10
-
7
-
-
0032941836
-
Gene-enhanced tissue engineering: Applications for bone healing using cultured periosteal cells transduced retrovirally with the BMP-7 gene
-
Breitbart AS, Grande DA, Mason JM, Barcia M, James T, Grant RT. Gene-enhanced tissue engineering: applications for bone healing using cultured periosteal cells transduced retrovirally with the BMP-7 gene. Ann Plast Surg 1999;42:488-95.
-
(1999)
Ann Plast Surg
, vol.42
, pp. 488-495
-
-
Breitbart, A.S.1
Grande, D.A.2
Mason, J.M.3
Barcia, M.4
James, T.5
Grant, R.T.6
-
8
-
-
0034605069
-
Clonal isolation of muscle-derived cells capable of enhancing muscle regeneration and bone healing
-
Lee JY, Qu-Petersen Z, Cao B, Kimura S, Jankowski R, Cummins J, Usas A, Gates C, Robbins P, Wernig A, Huard J. Clonal isolation of muscle-derived cells capable of enhancing muscle regeneration and bone healing. J Cell Biol 2000;150:1085-100.
-
(2000)
J Cell Biol
, vol.150
, pp. 1085-1100
-
-
Lee, J.Y.1
Qu-Petersen, Z.2
Cao, B.3
Kimura, S.4
Jankowski, R.5
Cummins, J.6
Usas, A.7
Gates, C.8
Robbins, P.9
Wernig, A.10
Huard, J.11
-
9
-
-
0034917376
-
Effect of bone morphogenetic protein-2-expressing muscle-derived cells on healing of critical-sized bone defects in mice
-
Lee JY, Musgrave D, Pelinkovic D, Fukushima K, Cummins J, Usas A, Robbins P, Fu FH, Huard J. Effect of bone morphogenetic protein-2-expressing muscle-derived cells on healing of critical-sized bone defects in mice. J Bone Joint Surg Am 2001;83:1032-9.
-
(2001)
J Bone Joint Surg Am
, vol.83
, pp. 1032-1039
-
-
Lee, J.Y.1
Musgrave, D.2
Pelinkovic, D.3
Fukushima, K.4
Cummins, J.5
Usas, A.6
Robbins, P.7
Fu, F.H.8
Huard, J.9
-
10
-
-
0036019199
-
Enhancement of bone healing based on ex vivo gene therapy using human muscle-derived cells expressing bone morphogenetic protein 2
-
Lee JY, Peng H, Usas A, Musgrave D, Cummins J, Pelinkovic D, Jankowski R, Ziran B, Robbins P, Huard J. Enhancement of bone healing based on ex vivo gene therapy using human muscle-derived cells expressing bone morphogenetic protein 2. Hum Gene Ther 2002;13:1201-11.
-
(2002)
Hum Gene Ther
, vol.13
, pp. 1201-1211
-
-
Lee, J.Y.1
Peng, H.2
Usas, A.3
Musgrave, D.4
Cummins, J.5
Pelinkovic, D.6
Jankowski, R.7
Ziran, B.8
Robbins, P.9
Huard, J.10
-
11
-
-
0036151114
-
Human skeletal muscle cells in ex vivo gene therapy to deliver bone morphogenetic protein-2
-
Musgrave DS, Pruchnic R, Bosch P, Ziran BH, Whalen J, Huard J. Human skeletal muscle cells in ex vivo gene therapy to deliver bone morphogenetic protein-2. J Bone Joint Surg Br 2002;84:120-7.
-
(2002)
J Bone Joint Surg Br
, vol.84
, pp. 120-127
-
-
Musgrave, D.S.1
Pruchnic, R.2
Bosch, P.3
Ziran, B.H.4
Whalen, J.5
Huard, J.6
-
12
-
-
0034776261
-
Muscle-based gene therapy and tissue engineering
-
Pelinkovic D, Lee JY, Adachi N, Fu FH, Huard J. Muscle-based gene therapy and tissue engineering. Crit Rev Eukaryot Gene Expr 2001; 11:121-9.
-
(2001)
Crit Rev Eukaryot Gene Expr
, vol.11
, pp. 121-129
-
-
Pelinkovic, D.1
Lee, J.Y.2
Adachi, N.3
Fu, F.H.4
Huard, J.5
-
13
-
-
0033914783
-
Gene therapy for bone formation: In vitro and in vivo osteogenic activity of an adenovirus expressing BMP7
-
Franceschi RT, Wang D, Krebsbach PH, Rutherford RB. Gene therapy for bone formation: in vitro and in vivo osteogenic activity of an adenovirus expressing BMP7. J Cell Biochem 2000;78:476-86.
-
(2000)
J Cell Biochem
, vol.78
, pp. 476-486
-
-
Franceschi, R.T.1
Wang, D.2
Krebsbach, P.H.3
Rutherford, R.B.4
-
14
-
-
0034690624
-
Gene therapy-directed osteogenesis: BMP-7-transduced human fibroblasts form bone in vivo
-
Krebsbach PH, Gu K, Franceschi RT, Rutherford RB. Gene therapy-directed osteogenesis: BMP-7-transduced human fibroblasts form bone in vivo. Hum Gene Ther 2000;11:1201-10.
-
(2000)
Hum Gene Ther
, vol.11
, pp. 1201-1210
-
-
Krebsbach, P.H.1
Gu, K.2
Franceschi, R.T.3
Rutherford, R.B.4
-
15
-
-
0032739075
-
Suppression of arthritic bone destruction by adenovirus-mediated csk gene transfer to synoviocytes and osteoclasts
-
Takayanagi H, Juji T, Miyazaki T, Iizuka H, Takahashi T, Isshiki M, Okada M, Tanaka Y, Koshihara Y, Oda H, Kurokawa T, Nakamura K, Tanaka S. Suppression of arthritic bone destruction by adenovirus-mediated csk gene transfer to synoviocytes and osteoclasts. J Clin Invest 1999;104:137-46.
-
(1999)
J Clin Invest
, vol.104
, pp. 137-146
-
-
Takayanagi, H.1
Juji, T.2
Miyazaki, T.3
Iizuka, H.4
Takahashi, T.5
Isshiki, M.6
Okada, M.7
Tanaka, Y.8
Koshihara, Y.9
Oda, H.10
Kurokawa, T.11
Nakamura, K.12
Tanaka, S.13
-
16
-
-
0036604082
-
Possible involvement of the vascular endothelial growth factor-Flt-1-focal adhesion kinase pathway in chemotaxis and the cell proliferation of osteoclast precursor cells in arthritic joints
-
Matsumoto Y, Tanaka K, Hirata G, Hanada M, Matsuda S, Shuto T, Iwamoto Y. Possible involvement of the vascular endothelial growth factor-Flt-1-focal adhesion kinase pathway in chemotaxis and the cell proliferation of osteoclast precursor cells in arthritic joints. J Immunol 2002;168:5824-31.
-
(2002)
J Immunol
, vol.168
, pp. 5824-5831
-
-
Matsumoto, Y.1
Tanaka, K.2
Hirata, G.3
Hanada, M.4
Matsuda, S.5
Shuto, T.6
Iwamoto, Y.7
-
17
-
-
0034707671
-
Reciprocal role of ERK and NF-kappaB pathways in survival and activation of osteoclasts
-
Miyazaki T, Katagiri H, Kanegae Y, Takayanagi H, Sawada Y, Yamamoto A, Pando MP, Asano T, Verma IM, Oda H, Nakamura K, Tanaka S. Reciprocal role of ERK and NF-kappaB pathways in survival and activation of osteoclasts. J Cell Biol 2000;148:333-42.
-
(2000)
J Cell Biol
, vol.148
, pp. 333-342
-
-
Miyazaki, T.1
Katagiri, H.2
Kanegae, Y.3
Takayanagi, H.4
Sawada, Y.5
Yamamoto, A.6
Pando, M.P.7
Asano, T.8
Verma, I.M.9
Oda, H.10
Nakamura, K.11
Tanaka, S.12
-
18
-
-
0031752946
-
Modulation of osteoclast function by adenovirus vector-induced epidermal growth factor receptor
-
Tanaka S, Takahashi T, Takayanagi H, Miyazaki T, Oda H, Nakamura K, Hirai H, Kurokawa T. Modulation of osteoclast function by adenovirus vector-induced epidermal growth factor receptor. J Bone Miner Res 1998;13:1714-20.
-
(1998)
J Bone Miner Res
, vol.13
, pp. 1714-1720
-
-
Tanaka, S.1
Takahashi, T.2
Takayanagi, H.3
Miyazaki, T.4
Oda, H.5
Nakamura, K.6
Hirai, H.7
Kurokawa, T.8
-
19
-
-
0036019364
-
Bone morphogenetic protein-transduced human fibroblasts convert to osteoblasts and form bone in vivo
-
Rutherford RB, Moalli M, Franceschi RT, Wang D, Gu K, Krebsbach PH. Bone morphogenetic protein-transduced human fibroblasts convert to osteoblasts and form bone in vivo. Tissue Eng 2002;8:441-52.
-
(2002)
Tissue Eng
, vol.8
, pp. 441-452
-
-
Rutherford, R.B.1
Moalli, M.2
Franceschi, R.T.3
Wang, D.4
Gu, K.5
Krebsbach, P.H.6
-
20
-
-
0035080361
-
Infection efficiency of type 5 adenoviral vectors in synovial tissue can be enhanced with a type 16 fiber
-
Goossens PH, Havenga MJ, Pieterman E, Lemckert AA, Breedveld FC, Bout A, Huizinga TW. Infection efficiency of type 5 adenoviral vectors in synovial tissue can be enhanced with a type 16 fiber. Arthritis Rheum 2002;44:570-7.
-
(2002)
Arthritis Rheum
, vol.44
, pp. 570-577
-
-
Goossens, P.H.1
Havenga, M.J.2
Pieterman, E.3
Lemckert, A.A.4
Breedveld, F.C.5
Bout, A.6
Huizinga, T.W.7
-
21
-
-
0036738338
-
Synergistic enhancement of bone formation and healing by stem cell-expressed VEGF and bone morphogenetic protein-4
-
Peng H, Wright V, Usas A, Gearhart B, Shen HC, Cummins J, Huard J. Synergistic enhancement of bone formation and healing by stem cell-expressed VEGF and bone morphogenetic protein-4. J Clin Invest 2002;110:751-9.
-
(2002)
J Clin Invest
, vol.110
, pp. 751-759
-
-
Peng, H.1
Wright, V.2
Usas, A.3
Gearhart, B.4
Shen, H.C.5
Cummins, J.6
Huard, J.7
-
22
-
-
0030684749
-
Targeted disruption of Cbfal results in a complete lack of bone formation owing to maturational arrest of osteoblasts
-
Komori T, Yagi H, Nomura S, Yamaguchi A, Sasaki K, Deguchi K, Shimizu Y, Bronson RT, Gao YH, Inada M, Sato M, Okamoto R, Kitamura Y, Yoshiki S, Kishimoto T. Targeted disruption of Cbfal results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell 1997;89:755-64.
-
(1997)
Cell
, vol.89
, pp. 755-764
-
-
Komori, T.1
Yagi, H.2
Nomura, S.3
Yamaguchi, A.4
Sasaki, K.5
Deguchi, K.6
Shimizu, Y.7
Bronson, R.T.8
Gao, Y.H.9
Inada, M.10
Sato, M.11
Okamoto, R.12
Kitamura, Y.13
Yoshiki, S.14
Kishimoto, T.15
-
23
-
-
0034455051
-
Regulation of osteoblast differentiation mediated by bone morphogenetic proteins, hedgehogs, and
-
Yamaguchi A, Komori T, Suda T. Regulation of osteoblast differentiation mediated by bone morphogenetic proteins, hedgehogs, and Cbfal. Endocr Rev 2000;21:393-411.
-
(2000)
Cbfal Endocr Rev
, vol.21
, pp. 393-411
-
-
Yamaguchi, A.1
Komori, T.2
Suda, T.3
-
24
-
-
0025857671
-
Recombinant human bone morphogenetic protein-2 stimulates osteoblastic maturation and inhibits myogenic differentiation in vitro
-
Yamaguchi A, Katagiri T, Ikeda T, Wozney JM, Rosen V, Wang EA, Kahn AJ, Suda T, Yoshiki S. Recombinant human bone morphogenetic protein-2 stimulates osteoblastic maturation and inhibits myogenic differentiation in vitro. J Cell Biol 1991;113:681-7.
-
(1991)
J Cell Biol
, vol.113
, pp. 681-687
-
-
Yamaguchi, A.1
Katagiri, T.2
Ikeda, T.3
Wozney, J.M.4
Rosen, V.5
Wang, E.A.6
Kahn, A.J.7
Suda, T.8
Yoshiki, S.9
-
25
-
-
0029914457
-
Effects of BMP-2, BMP-4, and BMP-6 on osteoblastic differentiation of bone marrow-derived stromal cell lines, ST2 and MC3T3-G2/PA6
-
Yamaguchi A, Ishizuya T, Kintou N, Wada Y, Katagiri T, Wozney JM, Rosen V, Yoshiki S. Effects of BMP-2, BMP-4, and BMP-6 on osteoblastic differentiation of bone marrow-derived stromal cell lines, ST2 and MC3T3-G2/PA6. Biochem Biophys Res Commun 1996; 220:366-71.
-
(1996)
Biochem Biophys Res Commun
, vol.220
, pp. 366-371
-
-
Yamaguchi, A.1
Ishizuya, T.2
Kintou, N.3
Wada, Y.4
Katagiri, T.5
Wozney, J.M.6
Rosen, V.7
Yoshiki, S.8
-
26
-
-
0025114650
-
The non-osteogenic mouse pluripotent cell line, C3H10T1/2, is induced to differentiate into osteoblastic cells by recombinant human bone morphogenetic protein-2
-
Katagiri T, Yamaguchi A, Ikeda T, Yoshiki S, Wozney JM, Rosen V, Wang EA, Tanaka H, Omura S, Suda T. The non-osteogenic mouse pluripotent cell line, C3H10T1/2, is induced to differentiate into osteoblastic cells by recombinant human bone morphogenetic protein-2. Biochem Biophys Res Commun 1990;172:295-9.
-
(1990)
Biochem Biophys Res Commun
, vol.172
, pp. 295-299
-
-
Katagiri, T.1
Yamaguchi, A.2
Ikeda, T.3
Yoshiki, S.4
Wozney, J.M.5
Rosen, V.6
Wang, E.A.7
Tanaka, H.8
Omura, S.9
Suda, T.10
-
27
-
-
0027946689
-
Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage
-
Katagiri T, Yamaguchi A, Komaki M, Abe E, Takahashi N, Ikeda T, Rosen V, Wozney JM, Fujisawa-Sehara A, Suda T. Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage. J Cell Biol 1994;127:1755-66.
-
(1994)
J Cell Biol
, vol.127
, pp. 1755-1766
-
-
Katagiri, T.1
Yamaguchi, A.2
Komaki, M.3
Abe, E.4
Takahashi, N.5
Ikeda, T.6
Rosen, V.7
Wozney, J.M.8
Fujisawa-Sehara, A.9
Suda, T.10
-
28
-
-
0030666372
-
Cbfal, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development
-
Otto F, Thornell AP, Crompton T, Denzel A, Gilmour KC, Rosewell IR, Stamp GW, Beddington RS, Mundlos S, Olsen BR, Selby PB, Owen MJ. Cbfal, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development. Cell 1997;89:765-71.
-
(1997)
Cell
, vol.89
, pp. 765-771
-
-
Otto, F.1
Thornell, A.P.2
Crompton, T.3
Denzel, A.4
Gilmour, K.C.5
Rosewell, I.R.6
Stamp, G.W.7
Beddington, R.S.8
Mundlos, S.9
Olsen, B.R.10
Selby, P.B.11
Owen, M.J.12
-
29
-
-
0030678549
-
Osf2/Cbfal: A transcriptional activator of osteoblast differentiation
-
Ducy P, Zhang R, Geoffroy V, Ridall AL, Karsenty G. Osf2/Cbfal: a transcriptional activator of osteoblast differentiation. Cell 1997;89:747-54.
-
(1997)
Cell
, vol.89
, pp. 747-754
-
-
Ducy, P.1
Zhang, R.2
Geoffroy, V.3
Ridall, A.L.4
Karsenty, G.5
-
30
-
-
0030904130
-
Green mice as a source of ubiquitous green cells
-
Okabe M, Ikawa M, Kominami K, Nakanishi T, Nishimune Y. Green mice as a source of ubiquitous green cells. FEBS Lett 1997;407:313-9.
-
(1997)
FEBS Lett
, vol.407
, pp. 313-319
-
-
Okabe, M.1
Ikawa, M.2
Kominami, K.3
Nakanishi, T.4
Nishimune, Y.5
-
31
-
-
0033533606
-
Expression of bone morphogenetic protein-2 via adenoviral vector in C2C12 myoblasts induces differentiation into the osteoblast lineage
-
Okubo Y, Bessho K, Fujimura K, Iizuka T, Miyatake S. Expression of bone morphogenetic protein-2 via adenoviral vector in C2C12 myoblasts induces differentiation into the osteoblast lineage. Biochem Biophys Res Commun 1999;262:739-43.
-
(1999)
Biochem Biophys Res Commun
, vol.262
, pp. 739-743
-
-
Okubo, Y.1
Bessho, K.2
Fujimura, K.3
Iizuka, T.4
Miyatake, S.5
-
32
-
-
0036900947
-
Core-binding factor β interacts with Runx2 and is required for skeletal development
-
Yoshida CA, Furuichi T, Fujita T, Fukuyama R, Kanatani N, Kobayashi S, Satake M, Takada K, Komori T. Core-binding factor β interacts with Runx2 and is required for skeletal development. Nat Genet 2002;32:633-8.
-
(2002)
Nat Genet
, vol.32
, pp. 633-638
-
-
Yoshida, C.A.1
Furuichi, T.2
Fujita, T.3
Fukuyama, R.4
Kanatani, N.5
Kobayashi, S.6
Satake, M.7
Takada, K.8
Komori, T.9
-
33
-
-
0034908229
-
The effects of transplantation of osteoblastic cells with bone morphogenetic protein (BMP)/camer complex on bone repair
-
Tamura S, Kataoka H, Matsui Y, Shionoya Y, Ohno K, Michi K, Takahashi K, Yamaguchi A. The effects of transplantation of osteoblastic cells with bone morphogenetic protein (BMP)/camer complex on bone repair. Bone 2001;29:169-75.
-
(2001)
Bone
, vol.29
, pp. 169-175
-
-
Tamura, S.1
Kataoka, H.2
Matsui, Y.3
Shionoya, Y.4
Ohno, K.5
Michi, K.6
Takahashi, K.7
Yamaguchi, A.8
-
34
-
-
0036830322
-
Cell-type-dependent up-regulation of in vitro mineralization after overexpression of the osteoblast-specific transcription factor Runx2/Cbfal
-
Byers BA, Pavlath GK, Murphy TJ, Karsenty G, Garcia AJ. Cell-type-dependent up-regulation of in vitro mineralization after overexpression of the osteoblast-specific transcription factor Runx2/Cbfal. J Bone Miner Res 2002;17:1931-44.
-
(2002)
J Bone Miner Res
, vol.17
, pp. 1931-1944
-
-
Byers, B.A.1
Pavlath, G.K.2
Murphy, T.J.3
Karsenty, G.4
Garcia, A.J.5
|