메뉴 건너뛰기




Volumn 354, Issue 2, 2007, Pages 567-573

CCN3/NOV inhibits BMP-2-induced osteoblast differentiation by interacting with BMP and Notch signaling pathways

Author keywords

BMP; CCN3; Hey1; Notch; NOV; Osteoblasts

Indexed keywords

ADENOVIRUS VECTOR; ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; CYSTEINE RICH PROTEIN 3; MESSENGER RNA; NEPHROBLASTOMA OVEREXPRESSED PROTEIN; NOTCH RECEPTOR; OSTEOCALCIN; PROTEIN; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG;

EID: 33846553080     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.01.029     Document Type: Article
Times cited : (90)

References (26)
  • 1
    • 0030690556 scopus 로고    scopus 로고
    • The missing bone
    • Rodan G.A., and Harada S. The missing bone. Cell 89 (1997) 677-680
    • (1997) Cell , vol.89 , pp. 677-680
    • Rodan, G.A.1    Harada, S.2
  • 2
    • 0034455051 scopus 로고    scopus 로고
    • Regulation of osteoblast differentiation mediated by bone morphogenetic proteins, hedgehogs, and Cbfa1
    • Yamaguchi A., Komori T., and Suda T. Regulation of osteoblast differentiation mediated by bone morphogenetic proteins, hedgehogs, and Cbfa1. Endocr. Rev. 21 (2000) 393-411
    • (2000) Endocr. Rev. , vol.21 , pp. 393-411
    • Yamaguchi, A.1    Komori, T.2    Suda, T.3
  • 4
    • 0025857671 scopus 로고
    • Recombinant human bone morphogenetic protein-2 stimulates osteoblastic maturation and inhibits myogenic differentiation in vitro
    • Yamaguchi A., Katagiri T., Ikeda T., Wozney J.M., Rosen V., Wang E.A., Kahn A.J., Suda T., and Yoshiki S. Recombinant human bone morphogenetic protein-2 stimulates osteoblastic maturation and inhibits myogenic differentiation in vitro. J. Cell Biol. 113 (1991) 681-687
    • (1991) J. Cell Biol. , vol.113 , pp. 681-687
    • Yamaguchi, A.1    Katagiri, T.2    Ikeda, T.3    Wozney, J.M.4    Rosen, V.5    Wang, E.A.6    Kahn, A.J.7    Suda, T.8    Yoshiki, S.9
  • 5
    • 0030678549 scopus 로고    scopus 로고
    • Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation
    • Ducy P., Zhang R., Geoffroy V., Ridall A.L., and Karsenty G. Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation. Cell 89 (1997) 747-754
    • (1997) Cell , vol.89 , pp. 747-754
    • Ducy, P.1    Zhang, R.2    Geoffroy, V.3    Ridall, A.L.4    Karsenty, G.5
  • 6
    • 0042891942 scopus 로고    scopus 로고
    • BMP-2-induced Runx2 expression is mediated by Dlx5, and TGF-beta 1 opposes the BMP-2-induced osteoblast differentiation by suppression of Dlx5 expression
    • Lee M.H., Kim Y.J., Kim H.J., Park H.D., Kang A.R., Kyung H.M., Sung J.H., Wozney J.M., Kim H.J., and Ryoo H.M. BMP-2-induced Runx2 expression is mediated by Dlx5, and TGF-beta 1 opposes the BMP-2-induced osteoblast differentiation by suppression of Dlx5 expression. J. Biol. Chem. 278 (2003) 34387-34394
    • (2003) J. Biol. Chem. , vol.278 , pp. 34387-34394
    • Lee, M.H.1    Kim, Y.J.2    Kim, H.J.3    Park, H.D.4    Kang, A.R.5    Kyung, H.M.6    Sung, J.H.7    Wozney, J.M.8    Kim, H.J.9    Ryoo, H.M.10
  • 9
    • 0037059614 scopus 로고    scopus 로고
    • The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation
    • Nakashima K., Zhou X., Kunkel G., Zhang Z., Deng J.M., Behringer R.R., and de Crombrugghe B. The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell 108 (2002) 17-29
    • (2002) Cell , vol.108 , pp. 17-29
    • Nakashima, K.1    Zhou, X.2    Kunkel, G.3    Zhang, Z.4    Deng, J.M.5    Behringer, R.R.6    de Crombrugghe, B.7
  • 10
    • 18144384703 scopus 로고    scopus 로고
    • Critical regulation of bone morphogenetic protein-induced osteoblastic differentiation by Delta1/Jagged1-activated Notch1 signaling
    • Nobta M., Tsukazaki T., Shibata Y., Xin C., Moriishi T., Sakano S., Shindo H., and Yamaguchi A. Critical regulation of bone morphogenetic protein-induced osteoblastic differentiation by Delta1/Jagged1-activated Notch1 signaling. J. Biol. Chem. 280 (2005) 15842-15848
    • (2005) J. Biol. Chem. , vol.280 , pp. 15842-15848
    • Nobta, M.1    Tsukazaki, T.2    Shibata, Y.3    Xin, C.4    Moriishi, T.5    Sakano, S.6    Shindo, H.7    Yamaguchi, A.8
  • 11
    • 0037119414 scopus 로고    scopus 로고
    • The nephroblastoma overexpressed gene (NOV/ccn3) protein associates with Notch1 extracellular domain and inhibits myoblast differentiation via Notch signaling pathway
    • Sakamoto K., Yamaguchi S., Ando R., Miyawaki A., Kabasawa Y., Takagi M., Li C.L., Perbal B., and Katsube K. The nephroblastoma overexpressed gene (NOV/ccn3) protein associates with Notch1 extracellular domain and inhibits myoblast differentiation via Notch signaling pathway. J. Biol. Chem. 277 (2002) 29399-29405
    • (2002) J. Biol. Chem. , vol.277 , pp. 29399-29405
    • Sakamoto, K.1    Yamaguchi, S.2    Ando, R.3    Miyawaki, A.4    Kabasawa, Y.5    Takagi, M.6    Li, C.L.7    Perbal, B.8    Katsube, K.9
  • 15
    • 0033623771 scopus 로고    scopus 로고
    • Effects of CTGF/Hcs24, a hypertrophic chondrocyte-specific gene product, on the proliferation and differentiation of osteoblastic cells in vitro
    • Nishida T., Nakanishi T., Asano M., Shimo T., and Takigawa M. Effects of CTGF/Hcs24, a hypertrophic chondrocyte-specific gene product, on the proliferation and differentiation of osteoblastic cells in vitro. J. Cell Physiol. 184 (2000) 197-206
    • (2000) J. Cell Physiol. , vol.184 , pp. 197-206
    • Nishida, T.1    Nakanishi, T.2    Asano, M.3    Shimo, T.4    Takigawa, M.5
  • 16
    • 19944427451 scopus 로고    scopus 로고
    • Connective tissue growth factor (CTGF) is regulated by Wnt and bone morphogenetic proteins signaling in osteoblast differentiation of mesenchymal stem cells
    • Luo Q., Kang Q., Si W., Jiang W., Park J.K., Peng Y., Li X., Luu H.H., Luo J., Montag A.G., Haydon R.C., and He T.C. Connective tissue growth factor (CTGF) is regulated by Wnt and bone morphogenetic proteins signaling in osteoblast differentiation of mesenchymal stem cells. J. Biol. Chem. 279 (2004) 55958-55968
    • (2004) J. Biol. Chem. , vol.279 , pp. 55958-55968
    • Luo, Q.1    Kang, Q.2    Si, W.3    Jiang, W.4    Park, J.K.5    Peng, Y.6    Li, X.7    Luu, H.H.8    Luo, J.9    Montag, A.G.10    Haydon, R.C.11    He, T.C.12
  • 17
    • 33645816535 scopus 로고    scopus 로고
    • CCN1/Cyr61 is regulated by the canonical Wnt signal and plays an important role in Wnt3A-induced osteoblast differentiation of mesenchymal stem cells
    • Si W., Kang Q., Luu H.H., Park J.K., Luo Q., Song W.X., Jiang W., Luo X., Li X., Yin H., Montag A.G., Haydon R.C., and He T.C. CCN1/Cyr61 is regulated by the canonical Wnt signal and plays an important role in Wnt3A-induced osteoblast differentiation of mesenchymal stem cells. Mol. Cell Biol. 26 (2006) 2955-2964
    • (2006) Mol. Cell Biol. , vol.26 , pp. 2955-2964
    • Si, W.1    Kang, Q.2    Luu, H.H.3    Park, J.K.4    Luo, Q.5    Song, W.X.6    Jiang, W.7    Luo, X.8    Li, X.9    Yin, H.10    Montag, A.G.11    Haydon, R.C.12    He, T.C.13
  • 18
    • 0036051343 scopus 로고    scopus 로고
    • Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta
    • Abreu J.G., Ketpura N.I., Reversade B., and De Robertis E.M. Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta. Nat. Cell Biol. 4 (2002) 599-604
    • (2002) Nat. Cell Biol. , vol.4 , pp. 599-604
    • Abreu, J.G.1    Ketpura, N.I.2    Reversade, B.3    De Robertis, E.M.4
  • 19
    • 33646102224 scopus 로고    scopus 로고
    • Expression and regulation of CCN genes in murine osteoblasts
    • Parisi M.S., Gazzerro E., Rydziel S., and Canalis E. Expression and regulation of CCN genes in murine osteoblasts. Bone 38 (2006) 671-677
    • (2006) Bone , vol.38 , pp. 671-677
    • Parisi, M.S.1    Gazzerro, E.2    Rydziel, S.3    Canalis, E.4
  • 20
    • 12944326284 scopus 로고    scopus 로고
    • Mouse hesr1 and hesr2 genes are redundantly required to mediate Notch signaling in the developing cardiovascular system
    • Kokubo H., Miyagawa-Tomita S., Nakazawa M., Saga Y., and Johnson R.L. Mouse hesr1 and hesr2 genes are redundantly required to mediate Notch signaling in the developing cardiovascular system. Dev. Biol. 278 (2005) 301-309
    • (2005) Dev. Biol. , vol.278 , pp. 301-309
    • Kokubo, H.1    Miyagawa-Tomita, S.2    Nakazawa, M.3    Saga, Y.4    Johnson, R.L.5
  • 21
    • 2942561008 scopus 로고    scopus 로고
    • Isolation and characterization of a mesenchymal cell line that differentiates into osteoblasts in response to BMP-2 from calvariae of GFP transgenic mice
    • Kadowaki A., Tsukazaki T., Hirata K., Shibata Y., Okubo Y., Bessho K., Komori T., Yoshida N., and Yamaguchi A. Isolation and characterization of a mesenchymal cell line that differentiates into osteoblasts in response to BMP-2 from calvariae of GFP transgenic mice. Bone 34 (2004) 993-1003
    • (2004) Bone , vol.34 , pp. 993-1003
    • Kadowaki, A.1    Tsukazaki, T.2    Hirata, K.3    Shibata, Y.4    Okubo, Y.5    Bessho, K.6    Komori, T.7    Yoshida, N.8    Yamaguchi, A.9
  • 23
    • 4444246433 scopus 로고    scopus 로고
    • Coordinated activation of notch, Wnt, and transforming growth factor-beta signaling pathways in bone morphogenic protein 2-induced osteogenesis. Notch target gene Hey1 inhibits mineralization and Runx2 transcriptional activity
    • Zamurovic N., Cappellen D., Rohner D., and Susa M. Coordinated activation of notch, Wnt, and transforming growth factor-beta signaling pathways in bone morphogenic protein 2-induced osteogenesis. Notch target gene Hey1 inhibits mineralization and Runx2 transcriptional activity. J. Biol. Chem. 279 (2004) 37704-37715
    • (2004) J. Biol. Chem. , vol.279 , pp. 37704-37715
    • Zamurovic, N.1    Cappellen, D.2    Rohner, D.3    Susa, M.4
  • 25
    • 33646550902 scopus 로고    scopus 로고
    • Notch 1 overexpression inhibits osteoblastogenesis by suppressing Wnt/beta-catenin but not bone morphogenetic protein signaling
    • Deregowski V., Gazzerro E., Priest L., Rydziel S., and Canalis E. Notch 1 overexpression inhibits osteoblastogenesis by suppressing Wnt/beta-catenin but not bone morphogenetic protein signaling. J. Biol. Chem. 281 (2006) 6203-6210
    • (2006) J. Biol. Chem. , vol.281 , pp. 6203-6210
    • Deregowski, V.1    Gazzerro, E.2    Priest, L.3    Rydziel, S.4    Canalis, E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.