The usefulness of cyclic diamidines with different core-substituents as antitumor agents

Bioorganic Chemistry

Volumn 36, Issue 4, 2008, Pages 183-189

  Spychała, Jarosław ^a  

^a ADAM MICKIEWICZ UNIVERSITY   (Poland)

Author keywords

Antitumor; Carbazoles; Fluorenes; Furans; Imidazolines; Piperidines; Pyrenes; Tetrahydropyrimidines; Triazines; Xylenes

Indexed keywords

2,5 BIS[4 (4,5,6,7,8,9 HEXAHYDRO 1H BENZIMIDAZOL 2 YL)PHENYL]FURAN; 2,7 BIS(4,5 DIHYDRO 4 METHYL 1H IMIDAZOL 2 YL)FLUORENE; 2,7 BIS(4,5 DIHYDRO 4,4 DIMETHYL 1H IMIDAZOL 2 YL)FLUORENE; 3,6 BIS(4,5 DIHYDRO 1H IMIDAZOL 2 YL) 9 METHYLCARBAZOLE; 4,6 BIS[3 (4,5 DIHYDRO 4 METHYL 1H IMIDAZOL 2 YL)PHENYL] 2 DIMETHYLAMINO 1,3,5 TRIAZINE; 4,6 BIS[4 (4,5 DIHYDRO 4 METHYL 1H IMIDAZOL 2 YL)PHENYL] 2 DIMETHYLAMINO 1,3,5 TRIAZINE; AMIDINE; ANTINEOPLASTIC AGENT; CARBAZOLE DERIVATIVE; N,N' BIS[4 (4,5 DIHYDRO 4 METHYL 1H IMIDAZOL 2 YL)BENZYL] 4,4' PROPYLENEBISPIPERIDINE; TRIAZINE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL STRAIN COLO 205; CELL STRAIN HL 60; CELL STRAIN MOLT 4; CELL STRAIN NCI H522; CELL STRAIN SF 268; CENTRAL NERVOUS SYSTEM TUMOR; COLON CANCER; CONTROLLED STUDY; CYTOTOXICITY; DNA BINDING; GLIOMA; HUMAN; HUMAN CELL; IN VITRO STUDY; KIDNEY CANCER; LEUKEMIA CELL; LUNG NON SMALL CELL CANCER; OVARY CANCER; PRIORITY JOURNAL; PROSTATE CANCER; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MOLECULAR STRUCTURE; PENTAMIDINE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 46149115603     PISSN: 00452068     EISSN: 10902120     Source Type: Journal    
DOI: 10.1016/j.bioorg.2008.05.002     Document Type: Article

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